This post was first published in 2017 but has been reviewed and updated in October 2020.
Theres a lot of confusing information and advice out there around sugar.
Does it cause cancer? Does sugar feed cancer cells, making them grow more aggressively? And how does the sugar we consume through food and drink affect our health, and what can be done about this?
In this post were taking a long hard look at sugar.
Well focus specifically on sugar and cancer, busting some myths and covering what researchers are studying in the hopes of finding new ways to treat people with cancer.
And well cover why the amount of sugar in our diets is cause for concern. A high-sugar diet can be bad news when it comes to cancer risk, but not for the reasons that often appear in the headlines.
But first the basics, what our bodies need sugar for and where it comes from in our diet.
Search for sugar and cancer on the internet and it doesnt take long to find alarming warnings that sugar is the white death and cancers favourite food.
But this idea that sugar is responsible for kick-starting or fuelling a cancers growth is an over-simplification of some complicated biology. Lets start with what sugar actually is.
Sugar comes in many different forms. The simplest form is just as a single molecule, such as glucose and fructose. These molecules of simple sugars can also stick together, either in pairs or as longer chains of molecules. All of these combinations of molecules are carbohydrates, and are our bodys main source of energy.
The form of sugar most of us will be familiar with is table sugar, which is a simple sugar that dissolves in water and gives things a sweet taste. Its proper name is sucrose, and its made up of crystals of glucose and fructose. Table sugar is refined, meaning its been processed to extract it from a natural source (usually sugar beet). Unprocessed foods can be high in simple sugars too, for example honey (also made mostly of glucose and fructose) is nearly pure sugar.
As chains of sugar get longer, they lose their sweet taste and wont dissolve in water anymore. These chains are called polysaccharides and form a large component of starchy foods. Starchy foods such as rice, bread, pasta and vegetables like potatoes might not taste sweet, but they are high in carbohydrate too.
Sugar, in some form, is in many things we eat. And this is good, because our bodies rely heavily on it to work.
Nearly every single part of our body is made of living cells. And its these cells that help us see, breathe, feel, think and much more.
While their jobs in the body may differ, one thing all these cells have in common is that they need energy to survive and perform their duties.
Cells somehow need to turn nutrients in our diet into a form of energy that they can use, called ATP. It would take a long time to explain this (if youre interested you might want to read more), but simplistically the process starts with glucose.
Glucose is the basic fuel that powers every single one of our cells. If we eat or drink things that are high in glucose, such as fizzy drinks, the glucose gets absorbed straight into our blood ready for our cells to use. If a starchy food, such as pasta, is on the menu, the enzymes in our saliva and digestive juices break it down and convert it into glucose. And if for some reason theres no carbohydrate in our diet, cells can turn fat and protein into glucose as a last resort, because they need glucose to survive.
Its here that sugar and cancer start to collide, because cancer is a disease of cells.
Cancer cells usually grow quickly, multiplying at a fast rate, which takes a lot of energy. This means they need lots of glucose. Cancer cells also need lots of other nutrients too, such as amino acids and fats; its not just sugar they crave.
Heres where the myth that sugar fuels cancer was born: if cancer cells need lots of glucose, then cutting sugar out of our diet must help stop cancer growing, and could even stop it developing in the first place. Unfortunately, its not that simple. All our healthy cells need glucose too, and theres no way of telling our bodies to let healthy cells have the glucose they need, but not give it to cancer cells.
Theres no evidence that following a sugar-free diet lowers the risk of getting cancer, or boosts the chances of surviving if you are diagnosed.
And following severely restricted diets with very low amounts of carbohydrate could damage health in the long term by eliminating foods that are good sources of fibre and vitamins.
This is particularly important for cancer patients, because some treatments can result in weight loss and put the body under a lot of stress. So poor nutrition from restrictive diets could also hamper recovery, or even be life-threatening.
Although theres no evidence that cutting carbohydrates from our diet will help treat cancer, important research has shown that understanding the abnormal ways that cancer cells make energy could lead to new treatments.
Back in the 50s, a scientist called Otto Warburg noticed that cancer cells use a different chemical process from normal cells to turn glucose into energy.
Healthy cells use a series of chemical reactions in small cellular batteries called mitochondria. The Warburg Effect, as it was dubbed following Ottos discovery, describes how cancer cells bypass their batteries to generate energy more rapidly to meet demand.
This shortcut for making energy might be a weakness for some cancers that gives researchers an advantage for developing new treatments.
Firstly, it opens up the potential for developing drugs that shut down cancer cells energy-making processes but dont stop healthy cells making energy. And researchers are testing drugs that work in this way.
Secondly, the abnormal processes in cancer cells can also leave them less able to adapt when faced with a lack of other nutrients, like amino acids. These potential vulnerabilities could lead to treatments too.
But these approaches are still experimental, and we dont know yet if treatments that starve cancer cells are safe or if they work.
Its certainly not grounds for cancer patients to try and do it themselves by restricting their diet during treatment and going back to our earlier point, it could be dangerous to do so.
If cutting out sugar doesnt help treat cancer, why then do we encourage people to cut down on sugary foods in our diet advice?
Thats because there is an indirect link between cancer risk and sugar. Eating lots of sugar over time can cause you to gain weight, and robust scientific evidence shows that being overweight or obeseincreases the risk of 13 different types of cancer. In fact, obesityis the single biggest preventable cause of cancer after smoking, which weve written about many times before.
And a study published in 2019 suggested there could be something else going on. Researchers found that people who drank more sugary drinks had a slightly increased risk of cancer, regardless of body weight. The study took weight in to account, but there are still lots of answered questions. More studies will be needed to investigate this.
Its free (or added) sugar were mainly concerned with when it comes to weight gain, not sugar that is naturally found in foods like fruits and milk or healthy starchy foods like wholegrains and pulses (which people should be eating more of*).
One ofthe easiest waysto lower youradded sugaris tocut down on sugary drinks, which are the largest source of sugar in the UK diet.
Some sugary drinks, such as fizzy drinks and energy drinks, can have more than the recommended daily maximum amount offree sugar in one serving alone. And while these extra calories promote weight gain, they offer no other nutritional benefits.
Other obviously sugary foods such as sweets, chocolate, cakes and biscuits are all best kept as treats too. But some foods that have hidden high amounts of added sugar may surprise you. Some breakfast cereals,ready meals (including healthy ones), pasta sauces and yoghurts can have shocking amounts of sugar added to them. Reading nutrition information labels and checking the ingredients list can help you choose lower sugar options.
While there are steps you and your family can take to cut down on added sugar, making these changes can be easier said than done. And its here that governments need to lend a hand.
Multiple cues push us as customers to stack junk food into our shopping baskets, even if we werent planning to, says Professor Linda Bauld, our cancer prevention champion based at the University ofEdinburgh. Thats why we want the Government to help create a better food environment where the healthy choice is the easy choice for everyone.
Were delighted that thesugar tax (Soft Drinks Industry Levy), which came into effect in April 2018, has been successful in removing a huge amount of sugar from fizzy drinks and our diets. This alongside other measures announced in the UK Governments 2020 obesity strategy should help to prevent millions of cases of overweight and obesity, and cancers linked to excess weight in the future, by reducing the amount of sugar the nation consumes.
But the Government hasnt made much progress in its plan to reduce the amount of sugar in the types of foods that are very popular with children. Four years into the programme, industry has failed to meet the voluntary targets set by Government, showing that a voluntary approach just isnt effective. This is also true for front-of-pack nutrition labelling where we want to see a consistent and mandatory approach.
Its also essential that reducing free sugars in our diets alongside other public health considerations be put at the forefront of the UK Governments upcoming trade deal negotiations in 2020 and beyond.
The story about sugar and cancer is complicated.
On the one hand, sugar itself doesnt cause cancer, and theres no way (at the moment) of specifically starving cancer cells of glucose without harming healthy cells too.
Theres also no evidence that adopting a diet very low in carbohydrate will lower your cancer risk or help as a treatment. And for patients, getting adequate nutrition is important for helping their bodies cope with treatment.
But were concerned about the amount of added sugar people are consuming because its promoting weight gain. And being overweight or obese increases the risk of least 13 types of cancer.
So the take home message is that although banishing sugar wont stop cancer in its tracks, we can all reduce our risk of getting cancer by making healthy choices, and lowering the amount of added sugar in our diets is a good way to help maintain a healthy body weight.
Emma
*While foods like fruit, milk and healthy starchy foods are high in carbohydrate, they have other important nutritional benefits. We should all be eating more whole fruits, vegetables, wholegrains and pulses as these nutritious foods are also high in fibre this not only helps your body digest the natural sugar more slowly (which helps you keep a healthy weight), it also reduces the risk of bowel cancer.
More on this topic
See the rest here:
Sugar and cancer what you need to know - Cancer Research UK - Science Blog
