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The Light Study, a Long-Term Research Study of Investigational Weight Loss Drug Contrave®, Begins Enrolling Patients …
Posted: June 6, 2012 at 10:17 pm
SAN DIEGO, June 6, 2012 /PRNewswire/ --Orexigen Therapeutics, Inc. (OREX) today announced that the Light Study, a long-term research study of Contrave (naltrexone SR/bupropion SR), a new, investigational drug being evaluated for weight loss, has begun enrolling patients at clinical sites throughout the United States. The Light Study is designed to assess the cardiovascular health outcomes of Contrave.
To view the multimedia assets associated with this release, please click: http://www.multivu.com/mnr/56480-lightstudy
Nearly 93 million Americans are affected by obesity, and that number is predicted to increase to 120 million Americans within the next five years.[i] More than one-third of adults in the United States are affected by obesity[ii]. Obesity increases the risk of heart disease, type 2 diabetes, some types of cancer, sleep apnea, and a variety of other conditions. Medical research suggests that losing just five percent of your body weight can significantly improve your health and reduce the risk of complications from type 2 diabetes and heart disease.[iii],[iv]
"We need new alternatives to fight the growing obesity epidemic in the United States," said Steven E. Nissen, M.D., Lead Investigator of the Light Study and Chairman of the Robert and Suzanne Tomsich Department of Cardiovascular Medicine at the Cleveland Clinic.[v] "One critical test of any weight loss treatment is its impact on cardiovascular health. The Light Study uses an innovative design that focuses on determining the safety and effectiveness of Contrave in patients who actually lose weight during treatment. This approach simulates how weight loss drugs are used in clinical practice. We think this trial design is a potentially important innovation in the development of new obesity therapies because it is sufficiently rigorous for regulatory authorities and feasible for drug developers, while also incorporating specific elements to help protect the safety of patients."
"Most people cannot achieve long term weight loss by diet and exercise alone," said Steven R. Smith, M.D., Professor and Scientific Director of The Florida Hospital Sanford-Burnham Translational Research Institute for Metabolism and Diabetes. "The Light Study is an important clinical research study evaluating the cardiovascular health outcomes of Contrave, which is designed to reduce appetite, increase metabolism, and control cravings and overeating behaviors."
In an effort to raise awareness of the obesity epidemic, the potential need for new and diverse treatment options, the benefits of reducing weight to improve certain measures of health and well being, and the Light Study, the Obesity Action Coalition (OAC) has partnered with Orexigen to launch the "Take Five to Live Light" campaign. The campaign encourages those affected by obesity to take five minutes to learn how losing just 5 percent of their weight can benefit cardiovascular health and to take five minutes to get screened for the Light Study. Individuals interested in participating in the Light Study can visit http://www.lightstudy.com to see if they qualify.
"We are proud to join forces with the OAC to educate the millions of Americans affected by obesity about the health benefits of weight loss," said Michael Narachi, President and Chief Executive Officer of Orexigen. "The OAC is a strong voice for those affected by obesity and an important partner in the fight against this epidemic. We encourage those who are interested in joining this cause to consider becoming a member of the OAC."
"The disease of obesity is extremely complex and requires a multidisciplinary team approach to treat it," said Joe Nadglowski, OAC President and CEO. "Many individuals affected by the disease of obesity need access to safe and effective treatment options; however, options are currently limited and new weight-loss management approaches are desperately needed. The OAC is excited to work with Orexigen to support obesity research for safe and effective options through the Light Study. This type of research is imperative in order to offer individuals affected by obesity valid, safe and effective tools to combat their weight and increase their quality of health."
Individuals may qualify for the Light Study if they are men age 45 or older or women age 50 or older; need to lose weight; and have a cardiovascular risk factor, such as heart disease or type 2 diabetes with certain heart risk factors.
In addition to the potential to receive Contrave, all who qualify and choose to participate in the Light Study will be part of an innovative, comprehensive weight management program called WeightMate. Delivered through an internet-based platform by accredited health and fitness professionals, WeightMate provides a convenient, progressive nutrition and exercise program with goal setting and tracking tools. WeightMate is powered by Sharecare, an interactive health and wellness social platform providing people with access to expert-developed answers, information and programs to live their healthiest life. Sharecare was created by Jeff Arnold, the founder of WebMD, and Dr. Mehmet Oz of "The Dr. Oz Show", to connect individuals with health experts and simplify the search for high-quality healthcare information.
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The Light Study, a Long-Term Research Study of Investigational Weight Loss Drug Contrave®, Begins Enrolling Patients ...
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Weight loss industry 'feeds off fat anxiety'
Posted: June 6, 2012 at 10:17 pm
WARWICK SMITH/Fairfax NZ
NOW AND THEN: Andrew Dickson's weight loss experience led to his thesis on weight anxiety and the role he says the dieting industry plays in perpetuating it.
Fat is a moral issue, according to new research that says the multibillion-dollar weight loss industry profits from manipulating people's anxieties.
Massey University PhD student Andrew Dickson decided to look into the industry after losing about 40 kilograms over four months from a starting weight of 135kg.
His thesis, The Other Side of Weight Loss, says those involved in the industry, such as Jenny Craig and Weight Watchers as well as government anti-obesity campaigns, personal trainers and reality TV shows such as The Biggest Loser were all complicit in giving "people something to attach to their anxiety".
Mr Dickson's own rapid weight loss in 2006 continued when he was prescribed the now-banned appetite suppressing drug Reductil.
He began feeling "ludicrously happy" as he started shedding about 5kg a week. Exercising about once a week "to the point of moderate dehydration", he would weigh himself "to get the thrill of a low weight appearing on the digital read-out. The scales and calorie counters were my gospel."
The dieting see-saw forced him into a cycle of "anxious tailspins" and that was when he decided to get to the heart of the phenomenon dubbed "weight anxiety".
After dropping to a low of about 85kg, Mr Dickson, a Massey management lecturer, now weighs 105kg. "The Western world is obsessed with the the 'right body' there's no right body and no wrong body."
He said one of the key props of the "fattist regime" was the Body Mass Index a flawed formula that divides weight by height-squared, which he said overstated the link between size and health.
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Safe Weight-Loss Tips for Wedding Season
Posted: June 6, 2012 at 10:16 pm
Over the years, brides-to-be have taken drastic measures to lose weight ahead of the Big Day: drinking a concoction of lemon juice, water, syrup, and cayenne pepper, wiring their mouths shut, and taking a pregnancy hormone while following the 500-calorie hCG diet.
But a feeding tube?
Yes, indeed. News media were abuzz recently with stories of brides resorting to the K-E Diet, in which a feeding tube funnels a slow drip of 800 calories of protein, water, and fatno carbs from the nose, down the esophagus, and into a person's stomach each day for 10 days. The draw: Patients can lose up to 20 pounds, says Oliver Di Pietro, a Florida-based internal medicine physician who charges $1,500 for the plan. One bride, his patient, reportedly had the tube removed after eight days because she had already lost the weight she wanted.
Medical and nutrition professionals immediately responded. "Rapid weight loss increases the risk of heart arrhythmias, dehydration, and electrolyte disturbances," says Ethan Lazarus, a family doctor in Denver who specializes in obesity medicine. Shedding pounds this quickly, he says, makes it likely that you will lose more lean body mass and water than fat. This can slow metabolism and result in an instant regain of weight once you go off the diet. "You may gain more than you lost," says Lazarus. Other effects include shrunken fingers and feet and a drooping facewhich can result in a loose wedding ring, flopping shoes, and a blushing bride with a dull expression, he says. And while the risk of inserting a feeding tube is small, Lazarus notes the possibility of lacerations in the sinuses (the tube goes down through the nose) and the esophagus, and some brides may experience vomiting and nausea.
Besides, a bride who wants to lose 20 pounds should start at least 10 weeks before the wedding, based on safe weight loss of no more than about two pounds a week, says Heather Mangieri, a registered dietitian and spokesperson for the Academy of Nutrition and Dietetics. (People who are much heavier can safely lose more, especially when they are first starting a weight-loss program, says Melina Jampolis, a physician nutrition specialist and author of The Calendar Diet . Eventually things will level out to 1 to 2 pounds a week for the average person, she says.)
Extreme measures like the K-E Diet aside, taking steps to accelerate weight loss as a key date approaches is perfectly okay if done sensibly. Below, experts share "final countdown" tips (no feeding tubes required).
Eliminate carbs or go low-carb. "The reality is in the short term, there is no question that low-carb diets work better, [for most people]," says Jampolis. "For a 10-day program, the lower you can go," the more weight you'll likely lose, she says. But Jampolis cautions against eating too few carbs, advising that brides consume between 50 and 75 grams per day to safely speed up weight loss. This can be achieved by eating lean protein, leafy greens, and healthy fats, such as nuts and seeds (watch the portions), and cutting back on processed grains, dairy, soy, sugar (including fruit sugar), and starchy vegetables. "Most women don't feel great if they go too low," she says. In the long run, know that low-carb diets have pitfalls, such as being unbalanced and difficult to stick to, says Jampolis.
Shrink and multiply. Eat five or six times a day, spaced out every two, three, or four hours, says Amira Lamb, a holistic nutritionist and personal trainer in New York. This can be three meals and two snacks or all mini meals. Eating regularly helps to maintain stable blood sugar and control hunger, she says. She adds that small meals are also better for digestion.
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Weight Loss Success: Stephanie Cupo Wanted To Get Healthy For Her Daughter And Lost Nearly 70 Pounds
Posted: June 6, 2012 at 10:16 pm
Got a success story of your own? Send it to us at success.stories@huffingtonpost.com and you could be featured on the site!
Name: Stephanie Cupo Age: 31 Height: 5'6" Before Weight: 252 pounds
How I Gained It: I have always been a "big girl." I considered myself to be "fat" in 5th grade, and all the skinny girls started making fun of me. I realized at that point what my ballet teacher meant when she said I had feet like an elephant, and that I should probably give up ballet for something where I could make more noise, like tap. I remember praying at night to wake up and be skinny. I was a very athletic child, so while I was never skinny through high school, I was able to maintain a normal weight of between 140 and 150 pounds.
It wasn't until after high school that I really began packing on the pounds. I dropped out of college at 19, and then dated a guy who liked "big girls" and made it his mission to ensure I was only attractive to him. I didn't break the 200-pound mark until my early 20s, and I decided to start trying crash diet after crash diet. I grew up in a family of naturally skinny people, so I never really learned how to eat properly or diet effectively.
Throughout my 20s, my weight fluctuated between 170 and 220 pounds, depending on what was going on in my life. I met my current husband when I was 24 and 190 pounds, and over the course of four years, my weight ballooned up 250 pounds. I couldn't believe the scale when I went to the doctor's office. At that time, we decided we wanted to try to have a child, and I was having some difficulty getting pregnant and also having health issues with blood pressure and cholesterol -- at 27 years old. So I once again started dieting and exercising the best I knew how and lost 20 pounds.
At 230 pounds, I became pregnant with my beautiful baby girl, Harper. I had such awful morning sickness, I actually ended up losing another 20 pounds in the first four months of my pregnancy and only gaining about 10 back up to her delivery. I had an emergency C-section with Harper on September 1, 2009, and walked out of the hospital five days later at 206 pounds.
Since I had a C-section, I was unable to exercise for several weeks, and once again, I started eating garbage food -- fast food because it was easiest with a husband working full time, a 15-year-old stepson and a newborn. I also had the strangest cravings for Red Bull and Double Stuf Oreo cookies for months after Harper's birth! I thought that was supposed to be over after I was no longer pregnant! I continued to wear my maternity clothes, and I felt myself get bigger and bigger and bigger. Finally, at a doctors' appointment, I weighed in at 252 pounds, my heaviest weight ever. I stopped weighing myself at that point because the number was so depressing, but I believe I probably was up to 260 pounds at my heaviest.
Breaking Point: I had blood work done and found that my weight had caused my triglycerides to spike to over 400. I ended up in the hospital a couple of months later in excruciating pain, only to have my gall bladder removed from gallstones. I learned that the gallstones were most likely in direct relation to my weight and extremely high triglycerides, and that if I didn't start losing weight and lower my cholesterol, I could end up in the hospital again with a much more serious issue -- or dead. At 29! Also, I was diagnosed with a herniated disc in my back with sciatica and was losing feeling in my toes, and I was told I could be crippled by the time I was 40 if I didn't lose some weight. My family, particularly my baby girl, made me realize that my weight no longer just affected me. If I was gone, it would destroy my family -- I couldn't do that to them. And I knew it was all in my control! I knew why I was fat! I wasn't fooling myself by saying "Oh, I've always been fat and I'll always be fat." I ate like crap and didn't exercise! Also, as materialistic as it sounds, I was fitting into plus size 18 to 20, and those clothes were getting tight. I couldn't bear the thought of having to buy a 22/24 size. I was disgusted with myself and allowing myself to get to this point. So instead of getting depressed and eating (like I used to do!), I decided it was time for a change!
How I Lost It: After considering gastric bypass and Lap Band surgery, I decided I was going to try this the old-fashioned way -- diet and exercise! I'm a very goal-oriented person, however I also get bored and disappointed very easily, so I knew I had to start setting some realistic, short-term goals to keep myself motivated. My first goal was a simple one: get down to the weight I was before I was pregnant. That weight came off pretty easily, so I kept setting weight goals. When I was bored with the weight-related goals, I started giving myself more materialistic goals, like shopping at non-plus-size stores.
At 209 pounds, I hit a wall. I just couldn't get any more weight or inches to come off. And like some kind of sign, my work decided to start a Weight Watchers at Work program, and I think I was one of the first people to sign up! I love the Weight Watchers program: realistic goals, no food plans to follow, earning points for exercise. I constantly feel like I'm being rewarded, and not being told there is something that I simply can't eat, I just have to eat less of it! Also, weighing in every Friday in front of my co-workers keeps me very honest. I even come to the meetings on Friday mornings on my days off to keep me on track. My coworkers and I call each other out if we see each other eating something in the caf we shouldn't be!
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Should Rex Ryan Appear on NBC's "The Biggest Loser" Weight-Loss Reality Show? Fan's View
Posted: June 5, 2012 at 9:21 pm
NBC's popular weight-loss reality TV series "The Biggest Loser" is hitting the road to find new contestants for Season 14, and I believe New York Jets head coach Rex Ryan would be a great fit for the show.
Ryan, 49, already dropped 90 pounds from his hefty 350-pound frame since undergoing lap-band surgery at NYU Medical Center in March of 2010, but there's plenty more fat left for him to drop.
Working out with world-renowned trainer Bob Harper would push Ryan to new levels in his weight-loss diet and exercise routine, as he's helped hundreds of people successfully lose weight.
According to an LATimes.com report, "Season 14 is scheduled to start airing in January 2013. Casting producers say they are looking for 'charismatic individuals' who are at least 18 years old, are at least 85 pounds overweight and would like a sweet shot at a grand prize of $250,000 for the person who loses the largest percentage of his or her body weight."
Rex Ryan is a charismatic individual who is at least 18 and still 85 pounds overweight. He fits every aspect of the description of contestants they are looking for.
It would be a win-win for all parties involved.
For the coach, it would be a chance for him to get in the best shape of his life, get healthy and feel great.
New York Jets fans need Ryan at the helm for the long-term, so we want him to think about staying healthy.
His large frame is fine for now, but you don't want to be carrying around 350 pounds as you approach your mid-50s and early-60s. That's just asking for a heart attack.
As for "The Biggest Loser," bringing Ryan on board would help to spruce up a stale format. We've already seen him shine bright on reality shows, as his brash personality delighted audiences nationwide when he appeared on HBO's "Hard Knocks."
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Weight-Loss Expert JJ Smith Helps 5 People Lose 50 Pounds in 2 Weeks … Find Out How!
Posted: June 5, 2012 at 9:20 pm
WASHINGTON, June 5, 2012 /PRNewswire/ --Last month 5 lucky participants were selected to participate in a 90 Day Weight Loss Challenge with JJ Smith, Nutritionist and Certified Weight-Loss Expert. In the first two weeks, she helped them lose a combined total of 50 pounds by following her Detox-Eat-Move (DEM) System.
The DEM System is a three-phased system that allows you to get rid of stubborn body fat and reverse some of your health issues and ailments, restoring your body to optimal health. JJ says, "One of the goals of the DEM Weight Loss Challenge is to help others learn how to help their own body burn fat effortlessly. I share my notes on exactly what guidance I gave to each of the 5 participants to help them get healthy, fast weight loss. This allows others to apply the same strategies to their own weight loss journey!" To see photos of the 5 participants and read their weekly reports to learn how JJ Smith has helped them shed 50 pounds in 2 weeks, click here: http://jjsmithonline.com/winners
The DEM System is a nutritionist-designed program that provides easy-to-follow guidelines for eating "clean and balanced" foods that not only help you lose weight, but cause you to look and feel younger and healthier than you have in years. Unlike other weight loss programs that focus on the typical advice of "eat less and exercise more," the DEM System features methods to detoxify the body, balance your hormones, and speed up your metabolism so you can burn more fat effortlessly. You can learn more about the DEM System at http://jjsmithonline.com/products/lose-weight.html.
About JJ Smith:
JJ Smith, http://www.JJSmithOnline.com, is the author of the #1 Amazon Bestseller and USA Today Bestseller, Lose Weight Without Dieting or Working Out. JJ is a nutritionist and certified weight-loss expert who has been featured on The Steve Harvey Morning Show, The Montel Williams Show and The Jamie Foxx Show and on the NBC, FOX, CBS, and CW Network television stations, as well as in the pages of Glamour, Essence, and Ladies Home Journal. Since reclaiming her health, losing weight, and discovering a "second youth" in her forties, bestselling author JJ Smith has become the voice of inspiration to women who want to lose weight, be healthy, and get their sexy back! JJ may be contacted on the web at http://www.JJSmithOnline.com, by email at info@jjsmithonline.com, on Twitter: jjsmithonline and Facebook Page: RealTalkJJ or at 202-558-5543.
This press release was issued through eReleases Press Release Distribution. For more information, visit http://www.ereleases.com.
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Weight-Loss Expert JJ Smith Helps 5 People Lose 50 Pounds in 2 Weeks ... Find Out How!
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VIVUS, Weight Loss, and the Patient Investor
Posted: June 5, 2012 at 8:15 am
By Jordo Bivona - June 4, 2012 | Tickers: ABT, AMLN, GSK, SNY, VVUS | 0 Comments
Jordo is a member of The Motley Fool Blog Network -- entries represent the personal opinions of our bloggers and are not formally edited.
Right from the outset, a child is exposed to a number of body image ideals that establishes the fact that our society places a lot of importance on the way we look. Though naysayers dismiss the importance of one's looks and physical appearance, we all know it way to well that our physical appearance is responsible to some extent for the way we are treated by people around us. With that in mind, the sensitive issue of being overweight always comes into picture. What one needs to understand is the difference between obesity that is linked with lifestyle patterns and obesity that is linked to medical or genetic causes.
In either case, the overweight individual experiences an immense pressure from within and from friends and family to reduce weight either for aesthetic or medical reasons. Either ways, being proactive about losing weight is always a good idea. However, the route to losing weight is what bothers most people. Dietary changes and regular exercise are extremely crucial in the reduction of weight and maintaining a healthy body. Moreover, lifestyle changes can impact a person's quest to losing weight as well. The most controversial of allweight-loss approachesis pharmacotherapy.
It is controversial because many people misuse weight loss drugs and still many others take the wrong ones, when they may actually require justlifestyle management techniquesincluding dietary changes and an active lifestyle. It is rather difficult to pinpoint and declare who would benefit the most from weight loss drugs. Most physicians agree that those who are morbidly obese and those who are at risk of severe health problems due to their obesity require weight loss medications.
If we were to consider pharmacological agents that reduce or control weight, we would have to wade through murky waters. FDA has approved only orlistat (Xenical) for long-term use. By inhibiting pancreatic lipase, it reduces the absorption of fat in the intestine.GlaxoSmithKline (NYSE: GSK)sells Orlistat as Alli in the U.S. and the U.K. whereasRoche Holding AG (RHHBY.PK)sells it as Xenical in other countries.
There are also generics of orlistat available in Russia and India. It has a risk of liver injury, but the documented cases are few andfar between. Sibutramine is an appetite suppressant that helps by quelling pangs of hunger. It was marketed byAbbott Laboratories (NYSE: ABT)until it was withdrawn from the market due to cardiovascular events and strokes. This drug is similar to Rimonabant, which was withdrawn from the market bySanofi-Aventis (NYSE: SNY)back in 2009 due to several risk factors.
Amylin Pharmaceuticals' (NASDAQ: AMLN)Exenatide is used to treat diabetes but is sometimes used as a weight loss drug as well. However, it is recommended only for those who have Type 2 Diabetes. Amylin's other diabetes drug pramlintide is currently being tested as a treatment for obesity among those who do not have diabetes. Green tea extract, raspberry ketone and other herbal extracts have been used to treat obesity with varying degrees of success. Nonetheless, we must bear in mind that weight loss drugs and treatments by major pharmaceutical companies are very few.
Of the newer drugs that are being investigated, I am particularly impressed withVivus' (NASDAQ: VVUS)Qnexa, which is a combination of the drugs phentermine and topiramate. Phentermine is known to suppress appetite, while topiramate is used as an anticonvulsant but causes weight loss as a side effect. FDAvoted to recommendQnexa as an obesity treatment option in February 2012. Final approval will happen sometime later in 2012. This is certainly going to drive Vivus' stock up the mark and seems to be a very promising drug to help people lose weight.
We must also consider pTeroPure pterostilbene, which is a pure form of trans-pterostilbene found in fruits and the bark of certain trees. Pterostilbene is known to have health properties similar to red wine, as it contains resveratrol. In fact, the company thatdeveloped the ingredient,ChromaDex (CDXC.OB)won the 2010 North American Frost & Sullivan Award for Most Promising Ingredient of the Year. pTeroPure pterostilbene is expected to be used in the treatment of cancer, blood pressure, diabetes, stress and anti-ageing. It is also expected to be a great weight loss drug but that is something that will have to be observed through the next few months.
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Can Weight Loss Surgery Hurt Me?
Posted: June 4, 2012 at 8:13 pm
When considering any type of weight loss surgery, it is important to know all of the potential side effects that come along with it. For instance, one of the most prevalent and most effective types of weight loss surgery, known as gastric banding, also carries a high amount of risk for those that use it. However, for people that qualify for gastric bands, the risk usually merits the return that often comes along with it. This is because the gastric banding obesity surgery is reserved for those that have a BMI or body mass index, at a very unhealthy level, usually around 40. For these people, weight loss surgery may be the best choice because their quality of life is much lower than it is for healthy weight individuals. Gastric band surgery is not without its potential setbacks, many of which include abdominal pain, constipation, seepage, infection, internal bleeding, and nausea. It is a good idea to know these facts when considering gastric banding because it also requires a minor change in lifestyle. For those that have gastric bands, food monitoring is more necessary than with most other weight loss surgery aftermaths.
This is because the body must still receive all the necessary nutrients that it did when not banded. So the individual that has undergone this surgery must know the amount of nutrients that they must consume to keep their weight down and keep their bodily functions at an all time high. The body must operate healthily during the time of which the gastric band is on the top portion of the stomach. Any additional complications can result in any number of adverse side effects.
Knowledge is absolutely necessary when looking at any kind of weight loss surgery. It is important to know all the possible side effects.
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GenoVive Launches in Mexico; Announces Partnership With Mexico City's Bariatric Support to Bring DNA-Based Weight Loss …
Posted: June 4, 2012 at 8:13 pm
NEW ORLEANS, LA--(Marketwire -06/04/12)- GenoVive, a pioneer in DNA-based, all-natural weight management solutions, today announced the company's first international partnership with Bariatric Support, one of Mexico City's leading bariatric support centers that offers a multi-disciplinary approach to prevention, wellness and weight loss. The partnership brings GenoVive's innovative approach to weight loss to Mexico, including the use of DNA testing that identifies an individual's unique genetic make-up that is the basis for customized meals and exercise plans to optimize weight loss and encourage long-term weight management.
As people in the United States and around the world continue to realize the harmful effects of obesity, GenoVive remains committed to the continued development of a long-term and comprehensive solution to weight management based on individual genetics and personalized nutrition and exercise. The company was founded to exploit the emerging field of nutrigenomics, which is the study of the effects of foods on gene expression and the role certain genes play in weight gain.
GenoVive's partnership with Bariatric Support will also allow for further research into how different cultures and ethnicity affect weight gain, loss and management. In fact, Mexico has the second highest incidence of obesity topped only by the United States.
"Bariatric Support is the ideal partner to launch GenoVive's breakthrough weight management science outside of the United States," said Vic Castellon, founder and CEO, GenoVive LLC. "Bariatric Support enjoys a solid reputation in Mexico City as a leader in weight loss programs. They have an active base of individuals who desire to lose weight in a healthy manner by getting to the root of their weight management challenges through meals and exercise programs developed specifically for their genetic profile. GenoVive remains committed to growing its program in the United States, and now internationally through this initial partnership in Mexico."
"GenoVive's innovative approach to weight loss based on DNA analysis and all-natural meal programs has already resonated tremendously with our patients in Mexico City," said Tatiana Palazuelos, nutritionist with Bariatric Support. "GenoVive's program complements our holistic and comprehensive approach to weight loss which includes physician visits and oversight plus nutrition and psychological counseling. We look forward to growing the partnership to benefit our patient base who desire customized weight loss programs that will work for the long term."
GenoVive's program starts with an easy-to-use, in-home DNA test. GenoVive analyzes the results and designs ideal weight management programs with home-delivered meals based on optimum fats, carbohydrates, proteins, plus exercise that works best with an individual's personal genetic makeup to increase the chances for long-term weight management. Each meal has been created with an optimal balance of macronutrients, vitamins and minerals, and at calorie levels that support healthy and sustainable weight loss.
Because food carries information to genes about the environment and serve as signals to our surrounding cells and can change the expression of certain genes, GenoVive is one of the only national weight management companies to offer meals that contain no growth hormones, antibiotics, preservatives, nitrates, sulfites, artificial sweeteners or sugar alcohols, or other similar incidental ingredients that may not be required to appear on the label.
"We understand obesity's multifactorial causation including lifestyle, eating patterns, psychological disorders, metabolic influence of our patients," said Denise Arcila, lead psychologist at Bariatric Support. "GenoVive complements and completes our multidisciplinary approach and is the only weight management option in Mexico to offer all-natural meals designed for our patients' unique genetic profiles. GenoVive is an easy and effective tool for our patients to learn about portion control while eating nutritionally balanced, all-natural meals which will help them control their weight and health over the long run."
Claudia Gonzales, founder and dietician, Bariatric Support, has been working with obesity patients for nearly 15 years, is already seeing results from patients on the GenoVive plan. "The ability to customize our patients' meals based on their specific genes helps them see results faster and encourages them to make even more lifestyle changes that lead to sustainable weight loss."
About GenoVive LLCFounded in 2008, GenoVive, a division of Genvis Bio Group, LLC, based in New Orleans, LA, represents a new approach to weight loss and sustained healthy eating. GenoVive's geneticists and food scientists developed customized, all-natural meal and exercise programs, featuring ideal combinations of macronutrients based on individual DNA. GenoVive is sold directly to the consumer at GenoVive.com and by phone with convenient home delivery. Follow GenoVive on Twitter @myGenovive, Facebook at http://www.facebook.com/GenoVive, and YouTube at http://www.youtube.com/GenoVivednadiet.
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Good News for Individuals Struggling with Weight Loss
Posted: June 4, 2012 at 8:13 pm
SAN DIEGO--(BUSINESS WIRE)--
A recent weight loss study shows that when participants know their genetic make-up, they have greater success losing weight and lowering their Body Mass Index (BMI). The California Schools VEBA - Pathway Genomics Corporation study evaluated weight loss results of 179 overweight California school employees. Results at 6 months showed that when employees took the Pathway Fit genetic test (of approximately 100 different genes and their variants related to sugar and fat metabolism, eating behaviors, best diet, micronutrients, and other parameters), they had significant weight loss success (some lost up to 40 pounds) when compared to employees who had previously tried to lose weight, under similar conditions, without the genetic test.
Both groups of employees worked with a VEBA health coach to help them develop an exercise and nutrition plan, and all received the same standard of care. However, the employees who knew and utilized their genetic-based diets and behaviors obtained greater weight loss (and other positive effects like decreased blood pressure) when compared with employees who had health coaching and standard of care only.
A participant in the study describes, The genetic study helped me change my overall behaviors and food choices and portion control. The understanding of my overall genes and physical health has helped me work more effectively with my VEBA health coach to achieve my weight loss goals.
The studyconducted in partnership with the California Schools VEBA (VEBA), Healthy Adventures Foundation and Pathway Genomics Corporationcollected interim results in January 2012. Principal investigator, Wendy Hileman, CEO, Healthy Adventures Foundation describes, The findings indicate that when participants have more information about their genetic predisposition, especially concerning exercise, eating behaviors, and diets, they have the validation they need to stick to a tailored program for the long haul, rather than quitting early on.
The Pathway Fit report is a health professional (M.D., D.O., N.P.) ordered saliva DNA test, where the participant simply spits in a plastic tube and sends it to Pathways lab to be analyzed. Through the analysis of genes and their variants (mutations)which are expressed in various organs, such as the brain, stomach, gut, muscle, pancreas, and directly in fat tissueparticipants gain insight about how their bodies process sugars, fats, nutrients and vitamins. This rigorous scientifically validated information is included in a detailed report that shows each participant how he or she may respond to a best diet, certain exercises and eating behaviors, traits such as bitter taste and caffeine metabolism, and his or her potential response to certain foods and micronutrients. Recently, there have been a number of double-blinded studies published showing the utility and positive psychological responses by patients of genetic testing for weight loss or nutrigenomic information (eg. Meisel, et al, Obesity, March 2012)
Michael Nova, M.D., Chief Medical Officer, Pathway Genomics, whose team developed the test says, The results of this preliminary study corroborate with the results were seeing in other areas of weight loss and personal nutrition management. When participants gain more knowledge about themselves, including understanding their metabolism, eating behaviors and response to exercise, as well as suggestions on the best ways to reach and maintain a healthy weight given their genetic predispositions, it helps lead them to make better health decisions and behavior changes for the long term.
Because the results were so compelling, VEBA, along with its other study partners, applied for a grant from the Allen Foundation to help it continue to roll out the relatively inexpensive Pathway Fit test to additional high-risk employees at participating VEBA school districts.
About the California Schools VEBA
The California Schools VEBA is a trust that offers school districts and employee organizations buying power and the structure to provide control over a variety of benefit issues. Benefits trusts continue to positively influence the quality of care delivered by contracted carriers and their providers.They also help members attain superior health care choices, rate stability, portability, affordability and quality for education employees.Total participation in the trust includes 40 southern California school districts and associations. The trust serves both employees and their dependents, totaling more than 89,000 members. For more information, visit http://www.vebaonline.com
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