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District Courts In New Jersey And New York Dismiss Securities Class Actions Against Life Science Companies Emphasizing the High Pleading Bar With…

Posted: May 6, 2020 at 12:45 pm

The United States District Courts for the District of New Jersey and the Southern District of New York recently dismissed putative securities class action complaints filed against life science companies in Smith v. Antares Pharma, Inc., et al. and Schaffer v. Nabriva Therapeutics PLC, et al.[1] The decisions make clear that the duty to disclose, imposed on life science companies by the federal securities laws, does not cover all conceivable information investors may find or consider relevant. Moreover, both courts held life science companies are not prohibited from expressing optimism about the prospects of FDA approval for products simply because of less-than-positive feedback from the regulator during the review process. The decisions, and their implications, are discussed below.

Antares Pharma Complaint

On December 21, 2016, Antares Pharma, Inc. (Antares) announced it submitted a New Drug Application (NDA) with respect to Phase 3 clinical studies, conducted in 2014 and 2015, for a testosterone replacement therapy (TRT) drug called QuickShot Testosterone which is currently marketed as Xyosted. Its stock price increased with the announcement. In October 2017, after Antares announced an October 11 FDA letter identifying deficiencies with the NDA, its common stock fell 37.80%. One week later, the FDA issued a Complete Response Letter (CRL) that rejected the NDA and identified clinically meaningful increases in blood pressure and incidents of depression and suicide. On January 11, 2018, Antares disclosed a 12.7% rate of hypertension observed in one of its Phase 3 studies.

Antares submitted a revised NDA in April 2018, which was approved by the FDA on October 1, 2018 with a black boxed warning for blood pressure increases, as well as warnings for risks of depression and suicide. Plaintiff contends Antaress stock price decreased 3% [o]n the heels of the revelation of approval with the requirement of a black box warning and risk of depression and suicide.

Nabriva Therapeutics Complaint

During the class period, Nabriva Therapeutics PLC (Nabriva) had only two products being considered by the FDA for marketing approval; it was not generating revenues from product sales, and did not expect to, unless one of the two drug candidates received approval. In October 2018, Nabriva filed a NDA with respect to Contepo, a drug intended to treat complicated urinary tract infections; this prompted FDA review, which would conclude with a final decision from the FDA by April 30, 2019. On December 14, 2018, the FDA issued a Form 483 letter[2] identifying inspectional observations it made, after visiting the manufacturing plant, that suggested the plant was not in compliance with applicable standards. Nabriva made several statements regarding the Contepo NDA during the class period, none of which mentioned the FDAs Form 483. Ultimately, the FDA did not approve the Contepo NDA. Instead, it issued a CRL withholding approval based substantially on the issues identified in the Form 483 letter. Upon this news, Nabrivas share price declined over 27%.

On August 16, 2019, Nabriva announced it would resubmit the Contepo NDA after rectifying the issues identified in the CRL. Because resubmission would retrigger a six-month review cycle, the FDA would likely not approve Contepo in 2019. Plaintiff alleged statements Nabriva made during the class period were misleading because they led investors to believe the FDA would approve the Contepo NDA in 2019, even though the Form 483 demonstrated that approval would be delayed beyond that year.

Dismissals of the Complaints

In both cases, the complaints were dismissed in their entireties, emphasizing that a life science companys duty to disclose is not unlimited and that it is not enough to plead that an optimistic forward-looking statement regarding approval prospects or timing of approval turns out to be incorrect.

Duty to Disclose

The Supreme Court has made clear that Section 10(b) of the Securities Exchange Act and Rule 10b5 do not create an affirmative duty to disclose any and all material information. Disclosure is required . . . only when necessary to make . . . statements made, in the light of the circumstances under which they were made, not misleading.[3]

In this vein, the Antares decision rejected plaintiffs argument that the failure to disclose the exact statistical risk of any adverse event was not actionable where the specific adverse event was identified as a common side-effect. The court similarly rejected plaintiffs allegation regarding the failure to provide data demonstrating the adverse event risks of its drug compared to the risks of other TRT treatments on the market, emphasizing that there was no duty to disclose such information unless Antares had disclosed some other comparative safety data that would render this omission misleading.

Puffery

The two dismissals also reiterate that puffery or vague statements of corporate optimism are not actionable under Section 10(b) and Rule 10b-5 because they are so general that a reasonable investor would not rely on them.

For example, the Antares court deemed statements that the drug was found to be safe, showed positive . . . safe data and that nothing unusual occurred regarding the FDAs review of the drug as vague and general statements of optimism. The court explained statements cannot be read in a vacuum, concluding a reasonable investor would understand Antaress statements on the drugs safety in light of the disclosure of adverse events. The Nabriva court similarly held company press release statements describing Contepos NDA submission as another major milestone, and Contepo as a first in class antibiotic, as classic examples of puffery because both are vaguely optimistic descriptions that make no particularly definite assertions of existing fact and thus provide little basis to mislead a reasonable investor.

Forward-Looking Statements

The dismissals also emphasized the protections afforded forward-looking statements under the safe harbor provision of the Private Securities Litigation Reform Act (PSLRA).

The Nabriva court rejected challenges to statements made by the company in its March 12, 2019 10-K regarding the risk of delay in FDA approval. Plaintiff argued that the characterization of the delay as a risk rather than a certainty was misleading in light of the concerns raised in the FDAs December 2018 Form 483 and that as a result the statement was not a forward-looking statement but rather a misstatement of existing fact. The court rejected the contention that the risks identified had already materialized, reasoning that the expected approval date was still over four months away and that the Form 483 reflected interim feedback and not a final decision.

Opinions

In dismissing the complaints, the courts reiterated that interpretations of clinical data are opinions and emphasized the heightened pleading requirements with respect to opinion statements following the Supreme Courts decision in Omnicare.[4]

In Antares, the court rejected plaintiffs argument regarding the falsity of the companys opinion about the physiologically normal benefits of the drug, concluding that plaintiff had failed to allege that the opinion was either objectively or subjectively false. The court explained that incidents of hypertension, depression or suicide did not render false the companys opinion regarding the drugs ability to provide patients with physiologically normal and steady levels of testosterone.

The court also held a statement regarding the positive safety data resulting from the study was an interpretation of the clinical trial data and as such an opinion. It reasoned the statement was not actionable absent facts showing Antares did not honestly believe the studies produced positive safety data and lacked a reasonable basis. [5] Similarly, the court held plaintiff failed to allege Antares lacked a reasonable basis for its opinion that the drug was safe, and noted a failure to allege that Antares was aware of this comparative risk data when [it] made the statement.

Conclusion

Antares and Nabriva are helpful precedents for pharmaceutical companies defending against securities class action lawsuits based on optimistic statements made about products undergoing FDA approval. The decisions emphasize that alleged misstatements cannot be read in a vacuum, and indicate that plaintiffs cannot simply rely on less-than-stellar feedback from the FDA, coupled with statements of corporate optimism made during the drug approval process.

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Revitalize You MD Reveals That Demand for Botox Remains Strong in Georgia – Press Release – Digital Journal

Posted: May 6, 2020 at 12:45 pm

Revitalize You M.D., based in Roswell, Georgia, has revealed that even with all restrictions due to the Covid-19 crisis situation, the demand for Botox in the state of Georgia is still growing. Botox offers a way to minimize or get rid of aging lines and wrinkles, which are the major feature of the skin aging process. Ever since the US Food and Drug Administration (FDA) has approved the cosmetic use of botulinum toxin, it has become one of the most common minimally invasive procedures, with more than 3 million treatments being done annually. Meanwhile, Revitalize You M.D. ensures that they only utilize top quality injectables, such as Botox.

Rachael Clark, a spokesperson for Revitalize You M.D., says, The world-famous botulinum toxin has been developed to treat moderate to severe frown lines. But thats not all what Botox is good for. At Revitalize You MD, we administer Botox treatments to improve hyperhidrosis or severe underarm sweating. We inject 50 units of Botox in each armpit to paralyze these overactive sweat glands, which cause you to start sweating less as a result.

Among the FDA approved products for treating wrinkles, the neuromodulators Botox and Dysport are for the purpose of minimizing or getting rid of the lines between the eyebrows, on the forehead, and around eyes through the relaxation of the muscles that cause the development of dynamic and static lines or wrinkles. Thus, the three most popular and medical uses of Botox are for treating forehead lines, crows feet lines, and frown lines. In addition, it can also be used for treating migraines and hyperhidrosis, which is excessive sweating of the hands, underarms, or feet. Those who would like to learn more about Revitalize You M.D. may want to check out their Instagram page.

Treatment with Botox results in the gradual relaxation of the muscles, allowing the overlaying skin to look smooth and without wrinkles. Either provided alone or in combination with other facial rejuvenation treatments, people can experience a significant enhancement in their appearance. An important advantage is that sedation or anesthesia is not required, and there is no recovery period that will prevent people from returning to work immediately. The results will become noticeable within three to seven days, and the effect of the treatment will usually last for about four to six months.

Revitalize You M.D. also offers other anti-aging treatments, aside from Botox. These are the hormone replacement therapy, IV therapy, and weight loss programs. Hormone replacement therapy is used to counteract the hormone imbalance that men and women alike experience as they age. For instance, when men reach the ages of 40 to 55, they start to experience a decline in their testosterone levels, which is known as andropause. Andropause has a number of symptoms, including increased fatigue, reduced energy levels, low sex drive, decreased strength and muscle mass, depression, lack of mental focus, and erectile dysfunction. Mens testosterone therapy is available at Revitalize You M.D. for andropause.

For women, the hormonal imbalance problems can occur from their late 30s and beyond. Symptoms include foggy memory, persistent weight gains, muscle loss, unexpected and excessive sweating vaginal dryness, consistent and growing fatigue, and lack of sexual desire. Hormone replacement therapy for women differs from that of men because of the symptoms, which means that that the timing and the treatments will differ.

Intravenous (IV) therapy is another treatment used to counteract the effects of aging. This offers a way to feed vitamins, minerals, and amino acids directly into the patients bloodstream to treat intracellular nutrient deficiencies. An important advantage of IV therapy is that it bypasses the gastrointestinal (GI) tract and the nutrients go directly into the system. Oral administration of the nutrients is much slower because they have to go through the GI system first before the nutrients can get into the bloodstream.

Those who are interested in Botox and other cosmetic treatments offered by Revitalize You M.D. may want to check out the Revitalize You M.D. website, including their GMB website, or contact them on the phone, or through email.

###

For more information about Revitalize You MD, contact the company here:

Revitalize You MDRachael Clark+1 678-304-1850info@revitalizeyoumd.com1105 Upper Hembree Rd ste b, Roswell,GA 30076, US

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Hormone Replacement Therapy Market Trends, Analysis and Forecast till 2029 Aminet Market Reports – amitnetserver

Posted: May 6, 2020 at 12:45 pm

The research study on Global Hormone Replacement Therapy market 2019 presents an extensive analysis of current Hormone Replacement Therapy market size, drivers, trends, opportunities, challenges, as well as key Hormone Replacement Therapy market segments. Further, it explains various definitions and classification of the Hormone Replacement Therapy industry, applications, and chain structure.In continuation of this data, the Hormone Replacement Therapy report covers various marketing strategies followed by key players and distributors. Also explains Hormone Replacement Therapy marketing channels, potential buyers and development history. The intent of global Hormone Replacement Therapy research report is to depict the information to the user regarding Hormone Replacement Therapy market forecast and dynamics for the upcoming years. The Hormone Replacement Therapy study lists the essential elements which influence the growth of Hormone Replacement Therapy industry. Long-term evaluation of the worldwide Hormone Replacement Therapy market share from diverse countries and regions is roofed within the Hormone Replacement Therapy report. Additionally, includes Hormone Replacement Therapy type wise and application wise consumption figures.

The Final Report will cover the impact analysis of COVID-19 on this industry.

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After the basic information, the global Hormone Replacement Therapy Market study sheds light on the Hormone Replacement Therapy technological evolution, tie-ups, acquisition, innovative Hormone Replacement Therapy business approach, new launches and Hormone Replacement Therapy revenue. In addition, the Hormone Replacement Therapy industry growth in distinct regions and Hormone Replacement Therapy R;D status are enclosed within the report.The Hormone Replacement Therapy study also incorporates new investment feasibility analysis of Hormone Replacement Therapy. Together with strategically analyzing the key micro markets, the report also focuses on industry-specific drivers, restraints, opportunities, and challenges in the Hormone Replacement Therapy market.View Source of RelatedReports :

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Global Hormone Replacement Therapy Market Segmentation 2019: Hormone Replacement TherapyThe study also classifies the entire Hormone Replacement Therapy market on basis of leading manufacturers, different types, various applications and diverse geographical regions. Overall Hormone Replacement Therapy market is characterized by the existence of well-known global and regional Hormone Replacement Therapy vendors. These established Hormone Replacement Therapy players have huge essential resources and funds for Hormone Replacement Therapy research as well as developmental activities. Also, the Hormone Replacement Therapy manufacturers focusing on the development of new Hormone Replacement Therapy technologies and feedstock. In fact, this will enhance the competitive scenario of the Hormone Replacement Therapy industry.

The Leading Players involved in global Hormone Replacement Therapy market are:

By Therapy Type (Human Growth Hormone (HGH) Replacement Therapy, Testosterone Replacement Therapy, Thyroid Replacement Therapy, Estrogen Replacement Therapy)

By Application (Growth Hormone Deficiency,Menopause, Hypothyroidism, Male Hypogonadism, and Others)

By Route of Administration (Oral, Parenteral, and Others)

By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) 

By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa )

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Worldwide Hormone Replacement Therapy Market Different Analysis:Competitors Review of Hormone Replacement Therapy Market: Report presents the competitive landscape scenario seen among top Hormone Replacement Therapy players, their company profile, revenue, sales, business tactics and forecast Hormone Replacement Therapy industry situations. Production Review of Hormone Replacement Therapy Market: It illustrates the production volume, capacity with respect to major Hormone Replacement Therapy regions, application, type, and the price. Sales Margin and Revenue Accumulation Review of Hormone Replacement Therapy Market: Eventually explains sales margin and revenue accumulation based on key regions, price, revenue, and Hormone Replacement Therapy target consumer. Supply and Demand Review of Hormone Replacement Therapy Market: Coupled with sales margin, the report depicts the supply and demand seen in major regions, among key players and for every Hormone Replacement Therapy product type. Also interprets the Hormone Replacement Therapy import/export scenario. Other key reviews of Hormone Replacement Therapy Market: Apart from the above information, correspondingly covers the company website, number of employees, contact details of major Hormone Replacement Therapy players, potential consumers and suppliers. Also, the strengths, opportunities, Hormone Replacement Therapy market driving forces and market restraints are studied in this report.

Highlights of Global Hormone Replacement Therapy Market Report:* This report provides in detail analysis of the Hormone Replacement Therapy and provides market size (US$ Million) and Cumulative Annual Growth Rate (CAGR (%)) for the forecast period: 2019 ; 2029. * It also elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for world Hormone Replacement Therapy market. * This study also provides key insights about Hormone Replacement Therapy market drivers, restraints, opportunities, new product launches, approvals, regional outlook, and competitive strategies adopted by the leading Hormone Replacement Therapy players. * It profiles leading players in the worldwide Hormone Replacement Therapy market based on the following parameters ; company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies and future plans. * Insights from Hormone Replacement Therapy report would allow marketers and management authorities of companies to make an informed decision with respect to their future product launches, market expansion, and Hormone Replacement Therapy marketing tactics. * The world Hormone Replacement Therapy industry report caters to various stakeholders in Hormone Replacement Therapy market. That includes investors, device manufacturers, distributors and suppliers for Hormone Replacement Therapy equipment. Especially incorporates government organizations, Hormone Replacement Therapy research and consulting firms, new entrants, and financial analysts. *Various strategy matrices used in analyzing the Hormone Replacement Therapy market would provide stakeholders vital inputs to make strategic decisions accordingly.

Global Hormone Replacement Therapy Market Report Provides Comprehensive Analysis of Following: ; Hormone Replacement Therapy Market segments and sub-segments ; Industry size ; Hormone Replacement Therapy shares ; Hormone Replacement Therapy Market trends and dynamics ; Market Drivers and Hormone Replacement Therapy Opportunities ; Supply and demand of world Hormone Replacement Therapy industry ; Technological inventions in Hormone Replacement Therapy trade ; Hormone Replacement Therapy Marketing Channel Development Trend ; Global Hormone Replacement Therapy Industry Positioning ; Pricing and Brand Strategy ; Distributors/Traders List enclosed in Positioning Hormone Replacement Therapy Market.

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Moreover, the report organizes to provide essential information on current and future Hormone Replacement Therapy market movements, organizational needs and Hormone Replacement Therapy industrial innovations. Additionally, the complete Hormone Replacement Therapy report helps the new aspirants to inspect the forthcoming opportunities in the Hormone Replacement Therapy industry. Investors will get a clear idea of the dominant Hormone Replacement Therapy players and their future forecasts.

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Latest Study explores the Testosterone Replacement Therapy Market Witness Highest Growth in near future – AlgosOnline

Posted: May 5, 2020 at 8:43 pm

The ' Testosterone Replacement Therapy market' research report now available with Market Study Report, LLC, is a compilation of pivotal insights pertaining to market size, competitive spectrum, geographical outlook, contender share, and consumption trends of this industry. The report also highlights the key drivers and challenges influencing the revenue graph of this vertical along with strategies adopted by distinguished players to enhance their footprints in the Testosterone Replacement Therapy market.

Request a sample Report of Testosterone Replacement Therapy Market at:https://www.marketstudyreport.com/request-a-sample/2430747?utm_source=algosonline.com&utm_medium=sp

The latest report on the Testosterone Replacement Therapy market contains a detailed analysis of this marketplace and entails information about various industry segmentations. According to the report, the market is presumed to amass substantial revenue by the end of the forecast duration while expanding at decent growth rate.

Details regarding the industry size, remuneration potential, and volume share are compiled in the report. It further lists out the drivers and challenges that will impact the growth of Testosterone Replacement Therapy market during the estimated timeframe.

The Testosterone Replacement Therapy market with respect to the geographical terrain:

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Additional highlights from the Testosterone Replacement Therapy market report are enlisted below:

Table of Contents:

Executive Summary: It includes key trends of the Testosterone Replacement Therapy market related to products, applications, and other crucial factors. It also provides analysis of the competitive landscape and CAGR and market size of the Testosterone Replacement Therapy market based on production and revenue.

Production and Consumption by Region: It covers all regional markets to which the research study relates. Prices and key players in addition to production and consumption in each regional market are discussed.

Key Players: Here, the report throws light on financial ratios, pricing structure, production cost, gross profit, sales volume, revenue, and gross margin of leading and prominent companies competing in the Testosterone Replacement Therapy market.

Market Segments: This part of the report discusses about product type and application segments of the Testosterone Replacement Therapy market based on market share, CAGR, market size, and various other factors.

Research Methodology: This section discusses about the research methodology and approach used to prepare the report. It covers data triangulation, market breakdown, market size estimation, and research design and/or programs.

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Some of the Major Highlights of TOC covers:

Chapter 1: Methodology & Scope

Definition and forecast parameters

Methodology and forecast parameters

Data Sources

Chapter 2: Executive Summary

Business trends

Regional trends

Product trends

End-use trends

Chapter 3: Testosterone Replacement Therapy Industry Insights

Industry segmentation

Industry landscape

Vendor matrix

Technological and innovation landscape

Chapter 4: Testosterone Replacement Therapy Market, By Region

Chapter 5: Company Profile

Business Overview

Financial Data

Product Landscape

Strategic Outlook

SWOT Analysis

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Testosterone Replacement Therapy Market Size by Top Key Players, Growth Opportunities, Incremental Revenue , Outlook and Forecasts to 2026 – Latest…

Posted: May 5, 2020 at 8:43 pm

Acerus Pharmaceuticals

Global Testosterone Replacement Therapy Market: Competitive Landscape

This section of the report lists various major manufacturers in the market. The competitive analysis helps the reader understand the strategies and collaborations that players focus on in order to survive in the market. The reader can identify the players fingerprints by knowing the companys total sales, the companys total price, and its production by company over the 2020-2026 forecast period.

Global Testosterone Replacement Therapy Market: Regional Analysis

The report provides a thorough assessment of the growth and other aspects of the Testosterone Replacement Therapy market in key regions, including the United States, Canada, Italy, Russia, China, Japan, Germany, and the United Kingdom United Kingdom, South Korea, France, Taiwan, Southeast Asia, Mexico, India and Brazil, etc. The main regions covered by the report are North America, Europe, the Asia-Pacific region and Latin America.

The Testosterone Replacement Therapy market report was prepared after various factors determining regional growth, such as the economic, environmental, technological, social and political status of the region concerned, were observed and examined. The analysts examined sales, production, and manufacturer data for each region. This section analyzes sales and volume by region for the forecast period from 2020 to 2026. These analyzes help the reader understand the potential value of investments in a particular country / region.

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Key Benefits for Stakeholders:

The report provides an in-depth analysis of the size of the Testosterone Replacement Therapy world market, as well as recent trends and future estimates, in order to clarify the upcoming investment pockets.

The report provides data on key growth drivers, constraints and opportunities, as well as their impact assessment on the size of the Testosterone Replacement Therapy market.

Porters 5 Strength Rating shows how effective buyers and suppliers are in the industry.

The quantitative analysis of the Testosterone Replacement Therapy world industry from 2020 to 2026 is provided to determine the potential of the Testosterone Replacement Therapy market.

This Testosterone Replacement Therapy Market Report Answers To Your Following Questions:

Who are the main global players in this Testosterone Replacement Therapy market? What is the profile of your company, its product information, its contact details?

What was the status of the global market? What was the capacity, the production value, the cost and the profit of the market?

What are the forecasts of the global industry taking into account the capacity, the production and the value of production? How high is the cost and profit estimate? What will be the market share, supply, and consumption? What about imports and export?

What is market chain analysis by upstream raw materials and downstream industry?

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Tags: Testosterone Replacement Therapy Market Size, Testosterone Replacement Therapy Market Trends, Testosterone Replacement Therapy Market Growth, Testosterone Replacement Therapy Market Forecast, Testosterone Replacement Therapy Market Analysis

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Male Hypogonadism Market Increasing Demand with Leading Key Players, Revenue Growth Analysis and Industry Share Price, Forecast 2025 – amitnetserver

Posted: May 5, 2020 at 8:43 pm

Global Male Hypogonadism Market: Snapshot

Hypogonadism in males refers to a condition in the male body where the testes show a significantly reduced level of functioning than normal. The overall result of male hypogonadism is a reduction in the rate of biosynthesis of male sex hormones. This state is more commonly known as interrupted stage 1 puberty. Hypoandrogenism, or the low androgen or testosterone level in a male can vary in severity from person to person. It is often the cause of partial or complete infertility. There are multiple forms of male hypogonadism and even more ways to classify them. Most endocrinologists commonly classify male hypogonadism on the basis of the level of defectiveness of the male reproductive system.

In many cases, doctors also measure the level of gonadotropins to classify a patient between primary and secondary male hypogonadism. Primary male hypogonadism refers to the cause of the condition being due to defective gonads. There are different types of primary male hypogonadism, including Turner syndrome and Klinefelter syndrome. Secondary male hypogonadism is caused by defects in pituitary or hypothalamic glands. They include Kallmann syndrome and hypopituitarism.

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Global Male Hypogonadism Market: Overview

Male Hypogonadism refers to a clinical condition, wherein the testes fail to produce enough testosterone leading to delayed puberty or incomplete development. The condition is related to impaired development of muscle mass, development of breast tissues, impaired body hair growth, and lack of deepening of the voice.

The male Hypogonadism market can be segmented by therapy, type, drug delivery, and geography.

The report presents an in-depth analysis of the global male hypogonadism market with current trends and future estimates to explain the imminent investment pockets. The quantitative analysis of the market for the forecast period from 2017 to 2025 will enable stakeholders to capitalize on the prevailing growth opportunities.

Global Male Hypogonadism Market: Trends and Opportunities

The top driver of the male hypogonadism market includes rising prevalence of testosterone deficiency among men, increasing infertility rates, and increasing awareness among individuals about hypogonadism treatment due to awareness drives organized by several governments across the world. Moreover, high risk of hypogonadism among the geriatric population with obesity and diabetes, and increasing prevalence of chronic disorders among the geriatrics are further expected to boost the markets growth.

However, factors such as high side effects of testosterone products are challenging the growth of testosterone replacement therapy market. Top players in the market are focused on research and development to introduce newer products with fewer or negligible side effects and improved results. For example, LPCN 1111, a product which is under development from Lipocine Inc., is a newer testosterone prodrug that utilizes Lipral technology for enhanced systemic absorption and for enhanced solubility of testosterone. Nevertheless, technological advancements are anticipated to extend new opportunities to the markets growth.

Global Male Hypogonadism Market: Regional Overview

The global male Hypogonadism market can be analyzed with respect to the regional segments of North America, Asia Pacific, Europe, Latin America, and the Middle East and Africa. North America held the majority share of the global market in the recent past and is expected to retain its dominant position in the near future. This is mainly due to the rise in the number of individuals suffering from primary and secondary conditions of hypogonadism, and rising awareness among individuals about treatment options for the condition. Moreover, the presence of ultra-modern healthcare infrastructure and increasing popularity of technologically advanced products are expected to offer new opportunities for top players in this market. The region is closely followed by Europe.

Asia Pacific is expected to offer lucrative opportunities to this market due to the modernization of the healthcare infrastructure in the emerging economies of India and China and the increasing awareness about the treatment for the condition. In Asia Pacific, the increasing prevalence of hypogonadism and infertility rates along with the rising geriatric population base with diabetes and obesity are propelling the growth of this market. China, Taiwan, and Malaysia are some of the countries that display the highest rate of male hypogonadism.

Major Companies Mentioned in Report

Some of the key players in the male Hypogonadism market include AbbVie Inc., Astrazeneca plc, Eli Lilly and Company Ltd., Merck & Co. Inc., SA, Finox Biotech, Laboratories Genevrier, Teva Pharmaceutical Industries Ltd., Allergan plc, Bayer AG, Endo International plc, IBSA Institut Biochimque, and Ferring.

Key players are focused on product approval for growth considerations and to cater to the changing demand of the industry. The introduction of innovative and technologically advanced products is also the focus of key players to increase their market share and for serving patients in a better manner.

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Male Hypogonadism Market Increasing Demand with Leading Key Players, Revenue Growth Analysis and Industry Share Price, Forecast 2025 - amitnetserver

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Hormone Replacement Therapy Market Study for 2020 to 2026 Providing Information on Key Players, Growth Drivers and Industry Challenges|Pfizer, AbbVie,…

Posted: May 5, 2020 at 8:43 pm

Complete study of the global Hormone Replacement Therapy market is carried out by the analysts in this report, taking into consideration key factors like drivers, challenges, recent trends, opportunities, advancements, and competitive landscape. This report offers a clear understanding of the present as well as future scenario of the global Hormone Replacement Therapy industry. Research techniques like PESTLE and Porters Five Forces analysis have been deployed by the researchers. They have also provided accurate data on Hormone Replacement Therapy production, capacity, price, cost, margin, and revenue to help the players gain a clear understanding into the overall existing and future market situation.

Key companies operating in the global Hormone Replacement Therapy market include , Eli Lilly, Pfizer, AbbVie, Novo Nordisk, Merck KGaA, Mylan, Bayer, Teva, Novartis, Abbott, Roche, Endo International, Ipsen, ANI Pharmaceuticals, TherapeuticsMD Hormone Replacement Therapy

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Segmental Analysis

The report has classified the global Hormone Replacement Therapy industry into segments including product type and application. Every segment is evaluated based on growth rate and share. Besides, the analysts have studied the potential regions that may prove rewarding for the Hormone Replacement Therapy manufcaturers in the coming years. The regional analysis includes reliable predictions on value and volume, thereby helping market players to gain deep insights into the overall Hormone Replacement Therapy industry.

Global Hormone Replacement Therapy Market Segment By Type:

, Estrogen Hormone, Growth Hormone, Thyroid Hormone, Testosterone Hormone, The proportion of estrogen hormone in 2018 is about 50%, and the proportion is in increasing trend from 2014 to 2018. Hormone Replacement Therapy

Global Hormone Replacement Therapy Market Segment By Application:

Menopause, Hypothyroidism, Growth Hormone Deficiency, Male Hypogonadism, Other Diseases

Competitive Landscape

It is important for every market participant to be familiar with the competitive scenario in the global Hormone Replacement Therapy industry. In order to fulfil the requirements, the industry analysts have evaluated the strategic activities of the competitors to help the key players strengthen their foothold in the market and increase their competitiveness.

Key companies operating in the global Hormone Replacement Therapy market include , Eli Lilly, Pfizer, AbbVie, Novo Nordisk, Merck KGaA, Mylan, Bayer, Teva, Novartis, Abbott, Roche, Endo International, Ipsen, ANI Pharmaceuticals, TherapeuticsMD Hormone Replacement Therapy

Key questions answered in the report:

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TOC

1 Study Coverage1.1 Hormone Replacement Therapy Product Introduction1.2 Market Segments1.3 Key Hormone Replacement Therapy Manufacturers Covered: Ranking by Revenue1.4 Market by Type1.4.1 Global Hormone Replacement Therapy Market Size Growth Rate by Type1.4.2 Estrogen Hormone1.4.3 Growth Hormone1.4.4 Thyroid Hormone1.4.5 Testosterone Hormone1.5 Market by Application1.5.1 Global Hormone Replacement Therapy Market Size Growth Rate by Application1.5.2 Menopause1.5.3 Hypothyroidism1.5.4 Growth Hormone Deficiency1.5.5 Male Hypogonadism1.5.6 Other Diseases1.6 Coronavirus Disease 2019 (Covid-19): Hormone Replacement Therapy Industry Impact1.6.1 How the Covid-19 is Affecting the Hormone Replacement Therapy Industry1.6.1.1 Hormone Replacement Therapy Business Impact Assessment Covid-191.6.1.2 Supply Chain Challenges1.6.1.3 COVID-19s Impact On Crude Oil and Refined Products1.6.2 Market Trends and Hormone Replacement Therapy Potential Opportunities in the COVID-19 Landscape1.6.3 Measures / Proposal against Covid-191.6.3.1 Government Measures to Combat Covid-19 Impact1.6.3.2 Proposal for Hormone Replacement Therapy Players to Combat Covid-19 Impact1.7 Study Objectives1.8 Years Considered 2 Executive Summary2.1 Global Hormone Replacement Therapy Market Size Estimates and Forecasts2.1.1 Global Hormone Replacement Therapy Revenue 2015-20262.1.2 Global Hormone Replacement Therapy Sales 2015-20262.2 Hormone Replacement Therapy Market Size by Region: 2020 Versus 20262.2.1 Global Hormone Replacement Therapy Retrospective Market Scenario in Sales by Region: 2015-20202.2.2 Global Hormone Replacement Therapy Retrospective Market Scenario in Revenue by Region: 2015-2020 3 Global Hormone Replacement Therapy Competitor Landscape by Players3.1 Hormone Replacement Therapy Sales by Manufacturers3.1.1 Hormone Replacement Therapy Sales by Manufacturers (2015-2020)3.1.2 Hormone Replacement Therapy Sales Market Share by Manufacturers (2015-2020)3.2 Hormone Replacement Therapy Revenue by Manufacturers3.2.1 Hormone Replacement Therapy Revenue by Manufacturers (2015-2020)3.2.2 Hormone Replacement Therapy Revenue Share by Manufacturers (2015-2020)3.2.3 Global Hormone Replacement Therapy Market Concentration Ratio (CR5 and HHI) (2015-2020)3.2.4 Global Top 10 and Top 5 Companies by Hormone Replacement Therapy Revenue in 20193.2.5 Global Hormone Replacement Therapy Market Share by Company Type (Tier 1, Tier 2 and Tier 3)3.3 Hormone Replacement Therapy Price by Manufacturers3.4 Hormone Replacement Therapy Manufacturing Base Distribution, Product Types3.4.1 Hormone Replacement Therapy Manufacturers Manufacturing Base Distribution, Headquarters3.4.2 Manufacturers Hormone Replacement Therapy Product Type3.4.3 Date of International Manufacturers Enter into Hormone Replacement Therapy Market3.5 Manufacturers Mergers & Acquisitions, Expansion Plans 4 Breakdown Data by Type (2015-2026)4.1 Global Hormone Replacement Therapy Market Size by Type (2015-2020)4.1.1 Global Hormone Replacement Therapy Sales by Type (2015-2020)4.1.2 Global Hormone Replacement Therapy Revenue by Type (2015-2020)4.1.3 Hormone Replacement Therapy Average Selling Price (ASP) by Type (2015-2026)4.2 Global Hormone Replacement Therapy Market Size Forecast by Type (2021-2026)4.2.1 Global Hormone Replacement Therapy Sales Forecast by Type (2021-2026)4.2.2 Global Hormone Replacement Therapy Revenue Forecast by Type (2021-2026)4.2.3 Hormone Replacement Therapy Average Selling Price (ASP) Forecast by Type (2021-2026)4.3 Global Hormone Replacement Therapy Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End 5 Breakdown Data by Application (2015-2026)5.1 Global Hormone Replacement Therapy Market Size by Application (2015-2020)5.1.1 Global Hormone Replacement Therapy Sales by Application (2015-2020)5.1.2 Global Hormone Replacement Therapy Revenue by Application (2015-2020)5.1.3 Hormone Replacement Therapy Price by Application (2015-2020)5.2 Hormone Replacement Therapy Market Size Forecast by Application (2021-2026)5.2.1 Global Hormone Replacement Therapy Sales Forecast by Application (2021-2026)5.2.2 Global Hormone Replacement Therapy Revenue Forecast by Application (2021-2026)5.2.3 Global Hormone Replacement Therapy Price Forecast by Application (2021-2026) 6 North America6.1 North America Hormone Replacement Therapy by Country6.1.1 North America Hormone Replacement Therapy Sales by Country6.1.2 North America Hormone Replacement Therapy Revenue by Country6.1.3 U.S.6.1.4 Canada6.2 North America Hormone Replacement Therapy Market Facts & Figures by Type6.3 North America Hormone Replacement Therapy Market Facts & Figures by Application 7 Europe7.1 Europe Hormone Replacement Therapy by Country7.1.1 Europe Hormone Replacement Therapy Sales by Country7.1.2 Europe Hormone Replacement Therapy Revenue by Country7.1.3 Germany7.1.4 France7.1.5 U.K.7.1.6 Italy7.1.7 Russia7.2 Europe Hormone Replacement Therapy Market Facts & Figures by Type7.3 Europe Hormone Replacement Therapy Market Facts & Figures by Application 8 Asia Pacific8.1 Asia Pacific Hormone Replacement Therapy by Region8.1.1 Asia Pacific Hormone Replacement Therapy Sales by Region8.1.2 Asia Pacific Hormone Replacement Therapy Revenue by Region8.1.3 China8.1.4 Japan8.1.5 South Korea8.1.6 India8.1.7 Australia8.1.8 Taiwan8.1.9 Indonesia8.1.10 Thailand8.1.11 Malaysia8.1.12 Philippines8.1.13 Vietnam8.2 Asia Pacific Hormone Replacement Therapy Market Facts & Figures by Type8.3 Asia Pacific Hormone Replacement Therapy Market Facts & Figures by Application 9 Latin America9.1 Latin America Hormone Replacement Therapy by Country9.1.1 Latin America Hormone Replacement Therapy Sales by Country9.1.2 Latin America Hormone Replacement Therapy Revenue by Country9.1.3 Mexico9.1.4 Brazil9.1.5 Argentina9.2 Central & South America Hormone Replacement Therapy Market Facts & Figures by Type9.3 Central & South America Hormone Replacement Therapy Market Facts & Figures by Application 10 Middle East and Africa10.1 Middle East and Africa Hormone Replacement Therapy by Country10.1.1 Middle East and Africa Hormone Replacement Therapy Sales by Country10.1.2 Middle East and Africa Hormone Replacement Therapy Revenue by Country10.1.3 Turkey10.1.4 Saudi Arabia10.1.5 UAE10.2 Middle East and Africa Hormone Replacement Therapy Market Facts & Figures by Type10.3 Middle East and Africa Hormone Replacement Therapy Market Facts & Figures by Application 11 Company Profiles11.1 Eli Lilly11.1.1 Eli Lilly Corporation Information11.1.2 Eli Lilly Description, Business Overview and Total Revenue11.1.3 Eli Lilly Sales, Revenue and Gross Margin (2015-2020)11.1.4 Eli Lilly Hormone Replacement Therapy Products Offered11.1.5 Eli Lilly Recent Development11.2 Pfizer11.2.1 Pfizer Corporation Information11.2.2 Pfizer Description, Business Overview and Total Revenue11.2.3 Pfizer Sales, Revenue and Gross Margin (2015-2020)11.2.4 Pfizer Hormone Replacement Therapy Products Offered11.2.5 Pfizer Recent Development11.3 AbbVie11.3.1 AbbVie Corporation Information11.3.2 AbbVie Description, Business Overview and Total Revenue11.3.3 AbbVie Sales, Revenue and Gross Margin (2015-2020)11.3.4 AbbVie Hormone Replacement Therapy Products Offered11.3.5 AbbVie Recent Development11.4 Novo Nordisk11.4.1 Novo Nordisk Corporation Information11.4.2 Novo Nordisk Description, Business Overview and Total Revenue11.4.3 Novo Nordisk Sales, Revenue and Gross Margin (2015-2020)11.4.4 Novo Nordisk Hormone Replacement Therapy Products Offered11.4.5 Novo Nordisk Recent Development11.5 Merck KGaA11.5.1 Merck KGaA Corporation Information11.5.2 Merck KGaA Description, Business Overview and Total Revenue11.5.3 Merck KGaA Sales, Revenue and Gross Margin (2015-2020)11.5.4 Merck KGaA Hormone Replacement Therapy Products Offered11.5.5 Merck KGaA Recent Development11.6 Mylan11.6.1 Mylan Corporation Information11.6.2 Mylan Description, Business Overview and Total Revenue11.6.3 Mylan Sales, Revenue and Gross Margin (2015-2020)11.6.4 Mylan Hormone Replacement Therapy Products Offered11.6.5 Mylan Recent Development11.7 Bayer11.7.1 Bayer Corporation Information11.7.2 Bayer Description, Business Overview and Total Revenue11.7.3 Bayer Sales, Revenue and Gross Margin (2015-2020)11.7.4 Bayer Hormone Replacement Therapy Products Offered11.7.5 Bayer Recent Development11.8 Teva11.8.1 Teva Corporation Information11.8.2 Teva Description, Business Overview and Total Revenue11.8.3 Teva Sales, Revenue and Gross Margin (2015-2020)11.8.4 Teva Hormone Replacement Therapy Products Offered11.8.5 Teva Recent Development11.9 Novartis11.9.1 Novartis Corporation Information11.9.2 Novartis Description, Business Overview and Total Revenue11.9.3 Novartis Sales, Revenue and Gross Margin (2015-2020)11.9.4 Novartis Hormone Replacement Therapy Products Offered11.9.5 Novartis Recent Development11.10 Abbott11.10.1 Abbott Corporation Information11.10.2 Abbott Description, Business Overview and Total Revenue11.10.3 Abbott Sales, Revenue and Gross Margin (2015-2020)11.10.4 Abbott Hormone Replacement Therapy Products Offered11.10.5 Abbott Recent Development11.1 Eli Lilly11.1.1 Eli Lilly Corporation Information11.1.2 Eli Lilly Description, Business Overview and Total Revenue11.1.3 Eli Lilly Sales, Revenue and Gross Margin (2015-2020)11.1.4 Eli Lilly Hormone Replacement Therapy Products Offered11.1.5 Eli Lilly Recent Development11.12 Endo International11.12.1 Endo International Corporation Information11.12.2 Endo International Description, Business Overview and Total Revenue11.12.3 Endo International Sales, Revenue and Gross Margin (2015-2020)11.12.4 Endo International Products Offered11.12.5 Endo International Recent Development11.13 Ipsen11.13.1 Ipsen Corporation Information11.13.2 Ipsen Description, Business Overview and Total Revenue11.13.3 Ipsen Sales, Revenue and Gross Margin (2015-2020)11.13.4 Ipsen Products Offered11.13.5 Ipsen Recent Development11.14 ANI Pharmaceuticals11.14.1 ANI Pharmaceuticals Corporation Information11.14.2 ANI Pharmaceuticals Description, Business Overview and Total Revenue11.14.3 ANI Pharmaceuticals Sales, Revenue and Gross Margin (2015-2020)11.14.4 ANI Pharmaceuticals Products Offered11.14.5 ANI Pharmaceuticals Recent Development11.15 TherapeuticsMD11.15.1 TherapeuticsMD Corporation Information11.15.2 TherapeuticsMD Description, Business Overview and Total Revenue11.15.3 TherapeuticsMD Sales, Revenue and Gross Margin (2015-2020)11.15.4 TherapeuticsMD Products Offered11.15.5 TherapeuticsMD Recent Development 12 Future Forecast by Regions (Countries) (2021-2026)12.1 Hormone Replacement Therapy Market Estimates and Projections by Region12.1.1 Global Hormone Replacement Therapy Sales Forecast by Regions 2021-202612.1.2 Global Hormone Replacement Therapy Revenue Forecast by Regions 2021-202612.2 North America Hormone Replacement Therapy Market Size Forecast (2021-2026)12.2.1 North America: Hormone Replacement Therapy Sales Forecast (2021-2026)12.2.2 North America: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.2.3 North America: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026)12.3 Europe Hormone Replacement Therapy Market Size Forecast (2021-2026)12.3.1 Europe: Hormone Replacement Therapy Sales Forecast (2021-2026)12.3.2 Europe: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.3.3 Europe: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026)12.4 Asia Pacific Hormone Replacement Therapy Market Size Forecast (2021-2026)12.4.1 Asia Pacific: Hormone Replacement Therapy Sales Forecast (2021-2026)12.4.2 Asia Pacific: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.4.3 Asia Pacific: Hormone Replacement Therapy Market Size Forecast by Region (2021-2026)12.5 Latin America Hormone Replacement Therapy Market Size Forecast (2021-2026)12.5.1 Latin America: Hormone Replacement Therapy Sales Forecast (2021-2026)12.5.2 Latin America: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.5.3 Latin America: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026)12.6 Middle East and Africa Hormone Replacement Therapy Market Size Forecast (2021-2026)12.6.1 Middle East and Africa: Hormone Replacement Therapy Sales Forecast (2021-2026)12.6.2 Middle East and Africa: Hormone Replacement Therapy Revenue Forecast (2021-2026)12.6.3 Middle East and Africa: Hormone Replacement Therapy Market Size Forecast by Country (2021-2026) 13 Market Opportunities, Challenges, Risks and Influences Factors Analysis13.1 Market Opportunities and Drivers13.2 Market Challenges13.3 Market Risks/Restraints13.4 Porters Five Forces Analysis13.5 Primary Interviews with Key Hormone Replacement Therapy Players (Opinion Leaders) 14 Value Chain and Sales Channels Analysis14.1 Value Chain Analysis14.2 Hormone Replacement Therapy Customers14.3 Sales Channels Analysis14.3.1 Sales Channels14.3.2 Distributors 15 Research Findings and Conclusion 16 Appendix16.1 Research Methodology16.1.1 Methodology/Research Approach16.1.2 Data Source16.2 Author Details

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Hormone Replacement Therapy Market Study for 2020 to 2026 Providing Information on Key Players, Growth Drivers and Industry Challenges|Pfizer, AbbVie,...

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The secret life of an anonymous speechwriter to the stars – The Guardian

Posted: May 4, 2020 at 10:45 am

I write speeches for people who can barely read their scripts because public speaking makes them nervous (statistically, public speaking is the number one fear, worse even than death). I write for people who are so compelling and beautiful that they could recite the alphabet and get a standing ovation. I write arguments that are recited in the House and Senate, in the seats of power. My words are on television and in stadiums that hold thousands of eager listeners. Im not there at all. The speeches, toasts and rallying cries I write go further than I ever will: I may not be seen, but I am heard. The words that do not matter when I speak for myself are amplified when I put them in the mouths of others. Because as anyone knows, its not just the words that matter. Its who says them, and when, and how.

Before I started writing for reality TV stars, musicians, political leaders and lecturers, I assumed that everyone wrote their own lines. Why wouldnt I think that? A well-written speech sounds like the person whos giving it. Or at least, it sounds like the person the speaker wants you to believe they are. Now I know that I was naive to assume that any public figure, even one who is a good writer, writes their own speeches and biographies and other ephemera. Ive learned that you are probably hearing something written in the style of by a very talented mimic.

Im an excellent mimic. This makes me a good speechwriter, but when I came out as nonbinary trans, it also became a survival skill. My welfare often depends on whether the non-transgender people around me see me as fully human and that means knowing exactly what to say, when, and in what tone. I needed to sound confident but not overbearing; friendly but not obsequious. My masculine presentation had to be balanced by kindness, consideration of others, and a willingness to cede the floor. I couldnt afford to blunder through any conversation, and I approached every interaction with more awareness and intention than ever before. Honestly, I spent a lot of time thinking about what Fred Rogers would say.

The only place where I didnt need to moderate my tone, where I could speak freely, was in my addiction recovery community. Through the first, dramatic stages of my transition, when my voice broke and when I was so afraid that my anger and panic was unwelcome in the world, the friends I knew there listened to me and encouraged me to keep sharing. They understood that, for people like us, honesty is lifesaving. People who swallowed their feelings relapsed, disappeared and died. I lost many friends to overdoses and substance-related accidents and suicides, silent deaths that went unacknowledged outside of our community. I kept showing up, and I kept talking. Tears, bile, all of me was welcome.

Outside of meetings, I couldnt express myself with the same openness. Although the words I spoke didnt change, my voice and the way I sounded altered the way that others heard me. Short statements, in a deep, gruff voice, can be heard as controlling, dismissive or rude, a sign of un-self-aware male privilege. The anger that commanded respect and interest when I presented as female became a liability as my voice lowered, acquiring the tones of patriarchy. Each word carried more weight, bigger consequences than before. Id had practice writing speeches for other people. Now, I had to learn new lines that were right for my voice and the body that carried it. Once my voice hit a certain frequency, I became my own ghostwriting client: how did I want to be perceived? What character was I playing now?

I started ghostwriting at the end of Barack Obamas first term as president. His writer, Jon Favreau, wrote sonorous lines for Obama. Those wide, soft vowels became musical. Like Winston Churchills, Obamas speeches were written in psalm-form, blocks that mimic the way people speak when they are going off script. The euphony in Obamas campaign speeches, alternately fiery and soothing, changed to the melody of authority once he was in office. I listened to Obama lean on the linguistic patterns of pastors, visionaries and teachers. His speeches used simple, two-syllable words, to avoid making him seem too much like an arugula-eating liberal. They had a signature three-verse structure, with a bridge in the middle. Once Id heard this music, I couldnt un-hear it.

The first time I wrote a speech for money, I was working as a research assistant for the manager of a hedge fund in Oregon. Dave* was also a member of a secret society that met annually for a black-and-white gala dedicated to the brilliance of Winston Churchill. At this gala, he told me, everyone wore a real tuxedo, penguin-style, with tails and a top hat. They slugged gallons of Churchills favorite drink Beefeater martinis and chomped cigars. The gala was a tense time, Dave explained, because of the elaborate system of speeches. Depending on his place in the hierarchy, any one of the guests would be expected to rise and disgorge a brief, bon-motstudded toast.

At that time, my voice was much higher, smoother and sweeter. I had not started hormone replacement therapy (HRT), and I still sounded like a woman. People dont listen to womens voices; they hear women speaking, but not the words they say. Research shows that voices with higher pitches, vocal fry, feminine vocal characteristics like a lisp, and gendered vocal tics such as the repeated use of like are ignored. Over five decades, the fundamental frequency of a test group of womens voices dropped by 23Hz, which correlates with womens entry into a previously male-dominated workplace. I did not have a high voice, but it was undeniably female. I was used to being read as a woman, discounted and ignored. The idea of Dave saying my words to a group of powerful, wealthy strangers shook something loose in me.

There were two caveats: the toast had to include a quote from Churchill that had never been used before, in the hundred-year history of the club; and it had to be short. I labored over this speech, getting stuck on all of the things I would say if I were the one in the spotlight. I could only hear myself and my own opinions. A speech like that would never make it into Daves shirt pocket, much less be read at this gala. I needed to alter my voice. I spent eight hours a day listening to Dave on the phone, as he bragged about the pitchers of sangria the waitress used to bring them from the VQ Cafe, back when Dave was a big deal, when he was young, before this dotcom bullshit. I knew exactly what he sounded like and how he wanted to be heard.

I imagined him, drunk and puffy in his Churchill costume, one hand on the tablecloth next to a plus-size martini and a half-eaten slab of roast beef smeared across a china plate, listing to port as he read the remarks Id written for him. I heard his voice, the money-basted sound of arrogant privilege. I looked at the toast again, picked up my pen, and started over. I was a good listener. I nailed it.

The speech I wrote for Dave was the first of many, and it worked because I stopped trying to write a speech and started imitating the best version of Dave. I wrote a script for the character he wanted to play that night, and it worked. For the duration of my job with him, I wrote his emails, fundraising letters and other speeches. I mocked him to my friends, pitch-perfect lines that could have come right out of his mouth. I said the things he hadnt thought of yet.

For the next six years, I wrote more speeches, lectures and manuscripts, mostly for people who didnt know who I was, aside from the writer. I didnt identify my gender when I did this work. I was just a voice on the phone, transcribing our conversations into ideas and paragraphs that would move an audience to the desired result. Want a million dollars in donations? I can write a speech that will achieve that. Want to pass lifesaving legislation? I can write one for that too. Want to change the way your audience feels about love, survival, health, politics, literature, community or hope? Thats my bread and butter. Sometimes, I wrote for people whose beliefs were diametrically opposed to my own. They were not difficult to mimic. In fact, those pieces were the easiest, because I could never confuse their voices for my own.

Then I started my physical transition. Within a couple of months on testosterone, I developed the usual hoarseness as the hormones affected my vocal fold structure, tissue integrity and thickness. My voice started to drop, a second adolescence. Yet my expressions did not change. When I spoke, my cadence and word choices were still female. I wandered around my subjects and avoided direct answers or simple statements. I preferred to agree without saying yes, refuse without saying no. I wrote in my clients voices, transcribing their desires. I went to meetings and barked about the unmanageable problems in my life: cravings, friends who caught a bad batch and didnt wake up, my disintegrating relationship with my immediate family, my fear of the painkillers that came with top surgery. It was a hard time. I was grateful for any ear, any place where I could go off script.

As I became audibly and physically queer, those spaces disappeared entirely. Id been socialized as female and already knew not to be abrasive in mixed company or share my opinions; before my transition, Id had the distinct experiences of being ignored and talked over by men. However, after a while, cis women stopped hearing me too. Or they heard me but didnt listen. My voice was husky from the early months of HRT. It was weak and airy, as though I had a throat cold; it vaporized in group conversations. I coughed out an idea and watched it disappear. More than once, I shared an opinion in a group and was ignored, but I noticed that when someone else parroted what Id said, they were acknowledged. I was afraid to speak up and challenge others conditional acceptance of me. I had so few places to go where I felt safe, giving up some airtime felt like a fair trade.

I stopped making declarative statements, stopped asserting myself. I kept quiet and listened. I reasoned that my actions spoke louder than my words, and that I didnt need my opinions or feelings acknowledged in order for them to be valid. There was no point in debating with people who didnt hear me when I spoke. I could let most ideas float by, unchallenged and unexplored. They were just noise. They didnt matter.

Then, I was hired to write a piece of testimony for a client, woven together with his personal experience with recovery from addiction. I wrote the first draft straight, drawing from his notes, but I barely had to glance at them to know what I needed to say. I was listening to my own story. Like me, my client had lost friends to preventable overdoses. He, too, struggled to make his voice heard outside of the recovery community. Unlike me, he had found a way and was using his story to create real change. He had access to lawmakers: he was meeting with Congress members, pushing policy to make sure naloxone was available in every sober living home in his state. His story was powerful and it burned in my ears as I wrote it down. I believed what I was writing; I felt the message. Although I wrote in my clients distinctive voice, I knew I was also speaking for myself.

I read the speech out loud in my studio to a hanging photo of my father. I recited it in the park to a smattering of pigeons. I heard the speechs music and the deep, implacable rage underneath it. Although Id written it for my client, I heard my own voice in it. What would I say if I wasnt afraid? I wished I could stand on a stage in front of hundreds of sign-clutching protesters and demand justice, as this client would, jabbing his finger toward the sky. Our time is now. What would I say if people actually listened? I went over the speech again, fine-tuning its message. I imagined my client, one of the bravest people I knew. I wanted to give him words that would speak for him, for me, for everyone who was listening. Every syllable had to move his audience. Lives hung in the balance: if the speech failed, that was one step back. The legislation tied to it might not pass. More people would die.

When I was done, I felt like Id handed over a piece of my heart. Id never cared so much before or put all of myself on the page that way. Id given the best of myself, the self I wished others perceived.

My client delivered the speech. His legislation passed. The news wire picked up the story, amplifying his words. The ripples spread. Later that week, I watched a video of my client on the day he read his story and had the jarring experience of hearing my voice come out of someone elses mouth. From his inflections to his gestures, we could have been mirror images. The crowd roared in all the right places. They resonated with the same passion Id felt when my client first hired me to write for him: his courage, transmittable, went from him to me to the massive audience that hung on his every word.

Although Id set out to be the channel for my clients voice, I had received so much more. I felt his confidence as he spoke. Writing for him awakened my own voice. The next time I heard an acquaintance sneer about dirty addicts who were a waste of resources, I cleared my throat. The person turned to me, eyes narrowed.

Fewer than 10% of people with substance use disorder ever get help of any kind because of stigmatizing language like dirty or clean, I said. The speech Id written trickled out of my mouth. Even people with substantial periods of recovery need support for their mental health. Addiction isnt a moral failing, and its not fair to frame it that way.

To my surprise, they nodded, leaned closer. They heard me. They listened.

* Daves name has been changed.

This story originally appeared on the digital storytelling platform Narratively. Looking for more great work? Here are some suggestions:

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The secret life of an anonymous speechwriter to the stars - The Guardian

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WWE news: Mick Foley wants Nancy Benoit inducted into Hall of Fame – GIVEMESPORT

Posted: May 2, 2020 at 5:46 pm

WWE icon Mick Foley has called for Chris Benoits tragically murdered wife Nancy to be inducted into the WWE Hall of Fame.

In 2007 over a three-day period, between June 22 and June 24, Benoit brutally murdered his wife Nancy and suffocated their seven-year-old son before hanging himself.

In an attempt to remember Nancys life in a different way, Foley has suggested that inducting her into the WWE Hall of Fame would be fitting.

The WWE originally paid tribute to Benoit, but after the murders were uncovered, he was completely erased from the companys history.

Foley took to social media to vent his thoughts, he said: For the past 13 years, Nancy Benoits life has been largely defined in the public eye by how she died. I think it is about time we changed that way of thinking.

Wouldnt it be nice if we could pause for a moment to remember instead, how she lived, how she worked, and to reflect on what her legacy in pro wrestling should be?

After the ring legend reached out to Sandra Toffoloni, Nancys sister, the two instantly started reflecting on the past.

Foley worked closely with Nancy in ECW and even closer with her when Benoit moved to WWE in 2000.

In a separate social media post, Foley addressed his proposal further, as he said: "Its an important discussion. But equally important to me, is that several fans, started talking about the career of Nancy Benoit, and how she should be remembered.

"For the first time I can recall, talk surfaced of Nancy possibly being inducted into the WWE Hall of Fame - a topic I had never really considered it before.

"But seeing the 'Dark Side of the Ring', re-establishing contact with Sandra, and looking back on Nancys career these past couple of weeks has been an eye-opener for me."

The brutal killings of Nancy and seven-year-old Daniel, as well as the suicide of Chris Benoit, were documented on a series called 'Dark Side of the Ring', which Foley narrated.

Scientists will forever be uncertain as to Benoits motive, however, WWE attorney Jerry McDevitt, appearing on Live with Dan Abrams on July 17, 2007, said that Benoit was prescribed testosterone as part of a treatment for testosterone replacement therapy.

This surgery is seen as common medical practice for people who had used steroids in the past.

Foley later on in his social media post said: "I would love to see Nancy inducted into the WWE Hall of Fame - under whatever name or character her family and WWE collectively decide.

"For her work as Fallen Angel, I believe she deserves to be included. For her work as Woman during her first run in WCW when she feuded with Rick Steiner, managed Doom, and managed The 4 Horsemen - I believe she deserves to be included.

"For her run in ECW, and her second run with WCW - where she helped create a fascinating angle that blurred the line between storyline and reality - I believe she deserves to be included.

Inducting Nancy Toffoloni into the WWE Hall of Fame is the right thing to do. Let us remember her, and define her for who she was and what she did in life.

With Foleys status in the company, it is thought his request will be seriously considered.

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WWE news: Mick Foley wants Nancy Benoit inducted into Hall of Fame - GIVEMESPORT

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Testosterone Replacement Therapy Market Overview, Top Companies, Region, Application and Global Forecast by 2026 – Latest Herald

Posted: April 27, 2020 at 9:49 am

Acerus Pharmaceuticals

Global Testosterone Replacement Therapy Market Segmentation

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