Category Archives: Testosterone

Those are just the well-known men who have talked about hormone therapies, of course. Speculation surrounds middle-aged rich guys like Jeff Bezos, who is rumored to be an investor in a buzzed-about anti-aging startup and seems to be aging in reverse into Billionaire Mr. Clean, with viral fit pics to match. (For the record, people close to Bezos attribute his transformation strictly to diet and exercise.)

In any case, it's not just the rich and famous: Doctor-approved doping is gaining ground among the everyday guy.

Youd be surprised with how many people are on hormone therapies, says Dr. Jessie Cheung, a dermatologist whose focus, in part, is on these treatments. You look, feel, perform, think, recover, and age better.

Testosterone is associated with physical changes like muscle growth and mental changes like confidence and aggression, though there is robust debate over the extent to which those effects should be understood as masculine, to what extent theyre shaped by existing social context, and whether these therapies show effects at a population level.

In any case, men are seeking these mental and physical changes, and Dr. Cameron Sepah, a professor of psychiatry at the school of medicine at the University of California, San Francisco, has noticed the uptick in popularity. Hes a clinician first, but has something of a vested interest as CEO of Maximus, which offers personalized treatment plans (a monthly membership is $149.99) to help men double their testosterone levels. Maximus men, Sepah claims, report having more energy, motivation, drive, and confidence.

They dont have the need for that afternoon nap anymore when they get sluggish toward the end of the day, he says.

Chris Jones, who joined Maximus about a year ago, is 39 and works as an attorney in Los Angeles. When the pandemic hit, Jones became interested in assessing his overall health. While he says he never felt particularly tired or off-balance, he also had never taken a testosterone test, and was surprised to see that his total level was 260 ng/dL.

Since popping the enclomiphene, Jones says his level has jumped to 730. I definitely feel more energy, more calm, more focus, he says. Just overall stronger and better. The naps and extra cups of coffee he occasionally needed in the afternoons have tapered off. And his verticalJones works with a dunk trainerhas gone up eight inches.

While testosterone therapy provides benefits, some doctors will caution against turning to testosterone replacement right away if youre feeling fatigued or less potent in the bedroom.

Theres all these lifestyle factors that will cause low testosterone or sort of simulate low-testosterone symptoms, says Dr. Kenneth Litwin, a physician who works with Fitzgerald at the Sandy Hook Clinic in Connecticut. If you help the person to identify that and help them work on all those things, they may never need testosterone.

Thats because testosterone levels can be affected by many factors. Getting eight hours of sleep or correcting a nutritional deficiency, like a low level of vitamin D, will restore your testosterone to its natural baseline. Strength training, looking for ways to decrease stress, and cutting out smoking are also key.

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How Testosterone Replacement Therapy Is Transforming Aging - GQ

There are many positive benefits of testosterone therapy. While testosterone is the male hormone, and testosterone replacement therapy is most often used to treat men with low testosterone, you may be surprised to learn that women can benefit from testosterone therapy as well.

Even though testosterone is an androgen, or male hormone, womens bodies do make and need testosterone, albeit, not as much as men, and for different things than men do. Unlike being necessary in vast amounts to provide for the development of maleness in men, in women, testosterone is necessary for:

When a women is experiencing low testosterone, all of the above can be negatively affected.

As in men, a womans testosterone level can fluctuate throughout the day, and can be impacted by many things from diet to her menstrual cycle. However, as in their male counterparts, the most significant drain on testosterone levels in women, occurs from the impact of ageing.

When you think about hormone replacement therapy (HRT) for women, the first thought that usually comes to mind is the typical estrogen therapy that is used to treat menopausal symptoms. However, when a woman is going through menopause, along with estrogen depletion, she is also losing her ability to produce adequate amounts of testosterone. A woman with low testosterone, will have trouble producing new blood cells, maintaining her libido or sex drive, and will find it harder to build muscle and burn fat.

When this is the case she will show the signs of low testosterone. The signs and symptoms of low testosterone in woman include:

Current research indicates that women who are on estrogen replacement for menopausal symptoms, can also benefit when testosterone therapy is added as an adjunct to estrogen replacement in these women. Testosterone, when used in this way, seems to specifically help with the sexual wellness issues typical of post-menopausal women. According to Dr. Alan Malabanan, assistant professor of medicine at Harvard Medical School, Studies of postmenopausal women have found that taking testosterone (often in addition to the hormone therapy women are already taking to treat menopause symptoms) increases sexual desire and pleasure compared with a placebo (inactive treatment).

In addition to helping women with the sexual health issues that often occur as they age, and testosterone levels drop, testosterone therapy has also been shown to help women in other matters of overall health and wellness. One of the most widely respected studies showing testosterones importance in maintaining a womans general health as well as sexual satisfaction was published in 2000 in the New England Journal of Medicine. Using traditionally accepted randomized, double-blind, placebo-controlled methodology, this study concluded that, transdermal testosterone improves sexual function and psychological well-being. Transdermal testosterone is a form of testosterone replacement therapy that is given using transdermal (skin) patches.

In addition to increasing the libido, and increasing health and vitality overall, testosterone therapy in women can also:

Testosterone is vital to the strength, vitality, and wellbeing of both men and women. However, in women, testosterone therapy must be given with particular care. In women, testosterone therapy is rarely given alone, but is prescribed as part of an overall program of Hormone Replacement Therapy (HRT) designed to bring all of her hormones back into proper balance.

Therefore it is imperative that any women who thinks that she may benefit from testosterone therapy, seek her treatment from a doctor, or HRT clinic that is skilled and experienced. This way, she can be sure that she will be getting the very best testosterone therapy tailored to her unique needs, body, and lifestyle.

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Testosterone Replacement Therapy for Women: Pros and Cons

Overview

Hormone replacement therapy is a bit of a misnomer. Its natural for mens testosterone levels to decrease as they get older. So, hormone therapy doesnt replace anything that is naturally missing.

Testosterone is required for:

However, the natural decrease of this hormone in men typically doesnt affect overall health any more than the aging process does. Medical experts disagree about the significance of a testosterone level decrease. They also disagree about the health benefits of hormone therapy use to combat the natural aging process in men, especially given the risks.

Learn more: Is low testosterone dangerous to your health?

Some men with unnaturally low levels of testosterone can benefit from hormone therapy. For example, the condition hypogonadism can cause unnaturally low levels of testosterone. Its a dysfunction of the testicles that prevents the body from producing the right amount of testosterone.

Whats less certain is whether testosterone therapy can benefit healthy men whose testosterone decline is simply caused by aging. This has been a difficult question for researchers to answer. Not many studies have observed the effects of testosterone therapy in men with healthy levels of the hormone. The studies that have were smaller and had unclear results.

Read more: Testosterone levels by age

If your doctor suggests testosterone therapy, several options are available. These include:

Side effects are a primary drawback of hormone therapy with testosterone. While some of the side effects are relatively minor, others are more serious.

Minor potential side effects of hormone therapy with testosterone include:

More severe potential side effects include:

An increased number of red blood cells can cause:

Hormone therapy can be a helpful treatment for men with unnaturally low levels of testosterone. However, it doesnt come without risks. These risks may outweigh the benefits if youre considering hormone therapy to make up for a natural decrease in testosterone levels.

Talk with your doctor about safer alternatives. Resistance exercise can help you build muscle mass, and walking, running, and swimming can help keep your heart strong.

Read more:
Hormone Replacement Therapy for Men: What to Know

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TRT Testosterone Replacement Therapy Clinic - Peter Uncaged MD

Testosterone replacement therapy can be helpful to those suffering from the effects of aging, such as the loss of muscle mass and bone density, as well as depression and anxiety due to low Testosterone levels in men. However, it has also been shown to positively affect diabetes in men who suffer from low Testosterone levels in two ways: by helping them lose weight and by managing their blood sugar more effectively. The rest of this article will discuss each of these effects in detail.

Testosterone is a sex hormone that helps control sex drive, bone mass, fat distribution, muscle mass, and strength. Every cell in our bodies has receptors for testosterone, affecting nearly every system in our body.

According to new research from The Journal of Clinical Endocrinology & Metabolism (JCEM), low Testosterone levels can lead to diabetes complications. Whats more? Study participants with low T were up to 45% more likely to develop type 2 diabetes than those with normal Testosterone levels. Those patients had lower insulin sensitivity than those with higher T-levels who also took part in the study.

Low Testosterone (low T) is a problem thats becoming more common. According to recent research, as many as 15 million men in America have low Tcommonly caused by obesity, aging, lifestyle choices, and anabolic steroid use. The problem with low T for men with diabetes is that it can lead to increased insulin resistance and make it more difficult to control blood sugar levels. Also, men will experience other symptoms such as erectile dysfunction, weight gain, and depression among others.

If youve been diagnosed with diabetes, talk to your doctor about whether or not you should be tested for low T. If you are found to have low T, they may recommend treatment so that you can start feeling better both physically and mentally!

Testosterone levels are critical to both sexual health and overall quality of life, making it even more important for men with diabetes to ensure that they keep their bodies as healthy as possible.

Testosterone and diabetes type 2 are a dangerous combination, since it causes increased insulin resistance, decreased glucose uptake by muscle tissue, and an increased risk of heart disease.

Its widely known that optimal levels of Testosterone are correlated with insulin sensitivity in both men and women; therefore low Testosterone levels may contribute to metabolic problems in both sexes. The bottom line is that T supplementation is a great option for men with lower-than-normal T levels who are overweight or obese and who have Type 2 diabetes.

Other Benefits of TRT for Men with Type 2 diabetes include:

The costs of hormone replacement treatment vary widely, depending on your age, how long you take Testosterone supplements, and whether or not you take other medications in addition to Testosterone.

Remember, diabetes is a lifestyle disease. Anything that impacts your weight, activity level, diet, or stress levels can contribute to complications and worsening health over time. So its important to watch out for not only high blood sugar but also high blood pressure, high cholesterol, excess body fat around your waist (in women), or higher-than-normal levels of triglyceridesall are risk factors for diabetes. If you already have diabetes, ask your doctor about getting a complete evaluation of all your lifestyle risk factors on an annual basis.

It is important for diabetic men to have an active lifestyle. Make a point to get regular exercise, avoid smoking, maintain a healthy diet and normal weight, wear sunscreen when outdoors, monitor blood sugar levels regularly, drink alcohol in moderation, if at all. Speak with your doctor or visit us atRenew Vitality TRT clinic in Clovis if you are interested in testosterone replacement therapy or other treatment options.

Photo byOnline MarketingonUnsplash

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Testosterone Replacement Therapy and Diabetes - UrbanMatter

The rising cases of male gonads dysfunction and the rising number of health problems among males resulted in a reduction of testosterone secretion. This further augmented the growth of the globaltestosterone replacement therapy market. Testosterone deficiency is considered a common health problem among men within the age group 40 to 70.

In terms of product, the market is dominated by the testosterone injections segment on account of the rising prevalence of medical conditions such as metabolic syndrome, dyslipidemia, diabetes, and obesity issues. Additionally, the availability of programs such as patient assistance is also helping augment the need for testosterone injections among other products.

According to a report by Transparency Market Research, the global testosterone replacement therapy market is projected to rise at a CAGR of 4.4% and reach a value of USD 2,296.2 million by the end of 2027 from a value of USD 1613.7 million earned in 2018.

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Rising Cases of type-2 Diabetes is projected to Add Boost to Overall Growth of Market

Skin testosterone is a medication that is applied to the skin to treat hypogonadism, a condition that keeps the body from making sufficient testosterone. A portion of the topically applied testosterone drug structures are creams, gels, and fixes. Testosterone replacement therapy (TRT) or androgen substitution treatment is perhaps the main class of chemical substitution treatment received universally. It involves the substitution of testosterone chemicals, particularly in male patients, when they experience the ill effects of hypogonadism, lower testosterone levels, and additionally low moxie. Testosterone is the essential male chemical liable for the improvement of male sexual qualities, spermatogenesis, and fruitfulness. Deficient creation of testosterone causes erectile brokenness. Erectile brokenness happens because of diminished testosterone creation to defeat this testosterone replacement therapy is utilized to work on the issue.

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Testosterone replacement therapy (TRT) is moderately new when contrasted with other drug treatments for end clients internationally. Notwithstanding, it is acquiring acknowledgment among patients and doctors because of expanding mindfulness concerning the advantages and viability of testosterone replacement therapy items. Additionally, the increasing number of geriatric population, coupled with the rising prevalence of hypogonadism among patients having type-2- diabetes are further expected to aid in the expansion of the global market for testosterone replacement therapy in the forecast duration. Furthermore, the increasing awareness about testosterone substitute therapy is also projected to add a boost to the overall growth of this market.

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Region-wise, the market is dominated by North America with the U.S. generating the largest revenue. The dominance of this region is attributed to the presence of better healthcare facilities and infrastructure. Additionally, the presence of a well-aware public and supportive government initiative in the form of reimbursement policies and medical insurances will also add a boost to the overall growth of the regional market in the coming years. On the other side, the market in Europe and the Asia Pacific will also witness notable growth on account of the rising investments in improving healthcare infrastructure and facilities and the advent of better therapeutic devices.

A few drug fabricating organizations have presented a wide scope of TRT drugs in the worldwide market. Key TRT drugs are accessible in six diverse item frames: gels or creams, infusions, inserts, patches, buccal glues, and orals. Key fixings used in various item frames incorporate testosterone, methyltestosterone, and testosterone esters, for example, testosterone undecanoate, testosterone enanthate, and testosterone cypionate. Advertising efforts by driving parts in the business for their marked items would help in expanding mindfulness about testosterone therapy among people. This expanded mindfulness is expected to support interest in testosterone replacement therapy items, which thus is probably going to drive the market.

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The information presented in this report is obtained from Transparency Market Research titled, Testosterone Replacement Therapy Market (Product Creams/Gels, Patches, Injections, Gums/Buccal Adhesives, Implants; Active Ingredient Testosterone, Methyl Testosterone, Testosterone Undecanoate, Testosterone Enanthate, Testosterone Cypionate) Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2019 2027.

Some of the prominent players of the global testosterone replacement therapy market include Ferring Holding SA, Pfizer Inc., Mylan N.V., Eli Lily Company, Bayer AG, AbbVie Inc., Clarus Therapeutics, Novartis AG, Kyowa Kirin International Plc., Endo Pharmaceuticals, Inc., Allergan Plc., and others.

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Testosterone Replacement Therapy Market Estimated to Rise Profitably during the Foreseeable Future - Digital Journal

The MarketsandResearch.biz study report examines the Global Testosterone Replacement Therapy Market growth rate from 2022 to 2028. Growth trends from the previous year, market share, industry analysis, growth factors, limitations, opportunities, challenges, and major market player profiling are all included in the study. The CAGR forecast for the market is presented as a percentage over a given time period. A The research also looks at how well-known players outperform their opponents.

The Testosterone Replacement Therapy market has benefitted both the sector and the global economy. The research looks at current trends, development possibilities, challenges, and roadblocks in depth. It uses SWOT analysis and Pestels Five Forces analysis, among other analytical techniques.

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The report offers a thorough examination of the top industry players in the global Testosterone Replacement Therapy market. Industry standards are influenced by technological advancements and product enhancements. The present development efforts associated with the product have an impact on the market growth rate. The studys financial data reveals certain businesses market positions.

Few of the markets most important players :

The type segment includes :

The application segment includes :

worldwide view on major regions is also included in the study, particularly :

ACCESS FULL REPORT: https://www.marketsandresearch.biz/report/164980/global-testosterone-replacement-therapy-market-2021-by-manufacturers-regions-type-and-application-forecast-to-2026

The companies look at both external and internal elements. Product approval regulations, economic changes, per capita income, industrial success in certain regions, and a variety of other socioeconomic features are examples of external influences. Internal factors include the research and development base, customer base, supply chain, labour force, market share in a specific place, and technology availability.

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This report can be customized to meet the clients requirements. Please connect with our sales team (sales@marketsandresearch.biz), who will ensure that you get a report that suits your needs. You can also get in touch with our executives on 1-201-465-4211 to share your research requirements.

Contact UsMark StoneHead of Business DevelopmentPhone: 1-201-465-4211Email: sales@marketsandresearch.biz

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Global Testosterone Replacement Therapy Market Growth, Trends, and Forecast 2022-2028to Industry Product and Top Companies AbbVie, Endo...

3 Hot Penny Stocks to Add to Your Watchlist Right Now

Recently, weve seen major volatility with both penny stocks and blue chips. While volatility can be used as an advantage, for those without a well-thought-out trading strategy, it can be detrimental.

If youre interested in investing in penny stocks, its important to understand some key concepts and principles. For one, you need to be familiar with what is affecting the stock market on both a short and long-term basis. You should also have a solid understanding of broader market trends so that you can anticipate changes before they happen and make smart investments accordingly.

[Read More] What Are Penny Stocks? A Beginners Guide To Making Money Trading

Additionally, many investors will trade with emotion, as information is always coming out and new penny stocks will always be trending. However, the most important thing is to have a strategy and not to let emotions get in the way of making sound investment decisions. So, as we are only a few days into the month, there are many days left to see if May will turn bullish. With that in mind, lets take a look at three penny stocks that are climbing during trading right now.

One of the largest gainers of the day on May 4th is CRXT stock. By midday, shares of CRXT stock had shot up by over 17% to more than $0.83 per share. This is a sizable gain that reflects recent positivity with the company. To understand why shares of CRXT stock are moving right now, we can look at its most recent announcement. On April 28th, the company announced a notice of allowance for patent claims regarding its Jatenzo compound. For those unfamiliar, Jatenzo is the first FDA-approved oral soft gel that to be used as a testosterone replacement therapy in adult men.

As we continue to grow the JATENZO brand, we are extremely pleased that we can further reinforce its robust intellectual property portfolio. Once issued, this new patent will be listed in FDAs Orange Book, thus bringing the total number of patents covering JATENZO in the United States to eight.

Only a few days before this, the company announced the closing of an upsized $30 million underwritten public offering. The company states that it will use the proceeds from this offering combined with its existing cash for working capital and general corporate purposes. Considering all of this exciting news and its big gain today, will CRXT be on your penny stocks watchlist?

While DBV Technologies 3.1% gain is nothing to write home about, it is substantial enough to take a closer look at. And with high volume during trading on May 4th, this bullish move could be a turnaround from its six month drop of over 56%.

The most recent news from the company came on May 2nd, when it reported its recent business developments as well as its Q1 2022 financial results. As far as updates go, the company announced that the FDA had granted it a Type C meeting regarding its new Viaskin Phase 3 study protocol. With over $74 million in cash, the company looks like it is in a decent place to continue growing its business. On May 12th, the company will host an ordinary and extraordinary meeting. And, this is the newest update that we will likely see for DBV Technologies.

[Read More] Penny Stocks With Huge Potential According To 4 Wall Street Analysts

If youre not familiar, DBV is currently developing Viaskin, which is a proprietary tech platform that could have major implications for use in immunotherapy. As a leading biotech penny stock, the company is working hard to get this product approved. Although it is highly volatile, its recent volume shows that DBVT stock could be worth keeping an eye on.

RIG stock is a penny stock that we have covered numerous times in the past few months. And today, shares of RIG stock are up by over 5.7%. This adds to a five day gain of more than 8.3% and a six month uptick of over 15%. If all that isnt enough, shares of RIG stock have also climbed by more than 35% YTD.

Aside from the recent bullish momentum in the energy sector, there is a lot to consider with Transocean itself. On May 2nd, the company reported its Q1 2022 financial results. In the results, the company posted contract drilling revenue of $586 million. This is less than the $621 million it reported during the fourth quarter of 2021. Despite this, it did see its revenue efficiency increase by around 0.4%.

The Transocean team continued to provide safe, reliable and efficient operations for our customers during the first quarter, resulting in approximately 98% uptime performance across our global fleet.

With this consistently dependable performance, our industry-leading fleet of high-specification, ultra-deepwater and harsh-environment floaters and the continued deployment of new technologies, we are well-positioned to capitalize on the ongoing recovery in the offshore drilling market.

While it is tough to justify the long term future of fossil fuels, there is a lot of interesting action occurring with RIG stock right now. Whether this makes it worth buying or not however, is up to you.

In the past few weeks, both penny stocks and blue chips have been prohibitively volatile. And, this massive volatility has meant that investing in penny stocks is not easy. But, if we look at what is going on in the world, we can begin to find ways to take advantage of these trading patterns.

[Read More] Top Penny Stocks to Buy Today? Must-Knows For Trading on May 4th

And, because there is so much movement with small caps, there are also a sizable amount of fluctuations to use to profit. So, with all of this in mind, do you think that penny stocks can make gains in May or not?

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Hot Penny Stocks You Need to Know About This Month - Miami County Republic

Claims made about "testicle tanning" in a clip promoting Tucker Carlson Originals: The End of Men have been branded as "misleading" by health experts.

In a viral clip about the Fox Nation episode, Carlson spoke to Andrew McGovernbilled as a "fitness professional"about supposed ways men could increase their testosterone levels.

McGovern, who is listed on LinkedIn as a personal trainer at LifeTime Inc., in Columbus, Ohio, suggested men could improve their testosterone levels by exposing themselves to red light therapy.

The Cleveland Clinic describes red light therapy as "an emerging treatment showing promise" in improving wound healing and acne, as well as reducing stretch marks and other common skin conditions.

In a viral Twitter clip, seen by some 3.5 million people since being shared on April 17, Carlson described the treatment as "testicle tanning" and said while it sounds "crazy," so is ignoring the "crash" of testosterone levels.

Since being shared online, the segment and, special as a whole, have been ruthlessly mocked online by users as well as by celebrities, including singer Kid Rock.

But health experts told Newsweek the claims made in the viral clip would not help men learn more about testosterone.

When asked whether viewers would find benefit in watching the video, Dr. Shanna Swan of New York's Icahn School of Medicine at Mount Sinai and author of Count Down, a 2017 book about the declining sperm count among men, said: "Not at all. That clip is very misleading."

Urologist Petar Bajic, MD, at the Cleveland Clinic's Glickman Urological and Kidney Institute, in Ohio, went further and told Newsweek that men considering red light therapy to enhance their testosterone levels would be wasting their money.

Dr. Bajic said: "The bottom line about red light therapy for low testosterone is that there is no evidence to support its use and no psychological basis for how it might even work because light wouldn't penetrate the skin to enter the testicles.

"Some folks have suggested a mechanism involving victim D, but for men with normal vitamin D, there's no evidence that making that level higher with light therapy has any impact on testosterone levels. This technology is not FDA approved for low testosterone and this means it has not been proven to be safe or effective for improving testosterone."

"I'd say to any man considering this treatment, it's not only a waste of time, but also a waste of money. There are a number of safe and effective treatments for low testosterone which are all covered by insurance for men who have this condition."

He added: "There's a lot of misleading information out there. I encourage everyone to be critical, come and see a reliable source, like a doctor, do your research from a reliable source, stick to what's been proven by the test of time."

Newsweek has contacted Fox News and LifeTime Inc. for comment.

The alleged decline in testosterone levels over recent decades has become an obsessive topic among some men online, with hundreds of articles and YouTube videos being made about the subject.

Swan told Newsweek there are few studies on the trends in male hormone levels, but noted a March 2022 University of Southern Denmark study found "a secular decline in testosterone has been observed."

She added the supporting data was "mostly European" and that a 2009 Travison study found testosterone decline in older American men.

Swan said the fall appeared to parallel declines in sperm count and that there was "good agreement" that obesity, lack of exercise and "binge drinking" played a role in both trends as well as the presence of chemicals, called anti-androgens, that can lower the body's testosterone.

Anti-androgens are found in food, personal care products and household products, according to Swan.

People who have low testosterone levels can suffer low libido, erectile dysfunction, less muscle mass and poor semen quality.

Concerns about male hormone levels could lead men to examine their diet or consider testosterone replacement therapy, to improve these symptoms.

Swan said while "exercise and other healthy behaviors may increase" the rates of the male hormone, "testosterone replacement therapy is risky and surprisingly, may decrease sperm count and quality."

She also told Newsweek that "food packaging and preparation may interfere with hormone levels" and that some foods "like meats and fatty foods have exogenous hormones and nutrients that may have effects on hormone levels."

She instead recommended that anyone who is concerned about their testosterone levels see an endocrinologist.

Originally posted here:
Tucker Carlson's Testicle Tanning 'Very Misleading,' Health Experts Say - Newsweek

Biotechnology company Halozyme Therapeutics, Inc. (Nasdaq: HALO) is set to acquire pharmaceutical company Antares Pharma, Inc. (Nasdaq: ATRS) in a deal that will create a leading drug delivery and specialty product company and diversify revenue, SEC filings say.

Pursuant to the agreement, Halozyme will acquire Antares for $5.60 per share in cash, for a total valuation of approximately $960 million. This will be funded with existing cash on hand and new sources of debt.

As stated in the filings, the transaction will have financial and strategic benefits. In particular, the deal will have immediate revenue and non-GAAP earnings accretion and it will have long-term financial benefits; new business development will enhance long-term growth consistent with strategic goals and priorities; there will be opportunities for large market expansion in high-revenue sectors; Antares products are high-growth and durable with a proven track record; and the companies have complementary platforms.

According to Antares website, its medicines include Xyosted, the first and only weekly auto-injector testosterone therapy; Tlando, an oral treatment for testosterone replacement therapy; and Nocdurna is the first and only sublingual tablet for the treatment of nocturia due to nocturnal polyuria in adults who wake up at least 2 times per night to urinate.

The addition of Antares, particularly with its best-in-class auto injector platform and specialty commercial business, augments Halozymes strategy, further strengthens our position as a leading drug delivery company and extends our strategy to include specialty products, Dr. Helen Torley, president and chief executive officer of Halozyme, said in a press release.

Accordingly, the deal is expected to accelerate Halozymes top- and bottom-line growth through 2027, with additional drivers of growth past 2027 like new products, therapies and partnerships. As noted in the filings, Antares business consists of a best-in-class, differentiated, royalty revenue generating auto injector platform business that offers broad licensing opportunity, and a commercial business, with three proprietary commercial products. Halozyme will purportedly expand these opportunities via its ENHANZE platform.

Furthermore, Halozyme anticipates expanding Antares core platform and capabilities to drive growth and revenue, as well as adding intellectual property protections. Additionally, Antares auto injector platform is suitable for use with a broad range of medications. As a result, this versatility enables a highly licensable business with significant revenue upside.

We are pleased to have reached this agreement with Halozyme, as this transaction showcases the value of Antares highly complementary business, provides our shareholders with attractive and certain value, and brings together industry-leading expertise and drug delivery platforms to accelerate growth and create new opportunities, Robert F. Apple, president and chief executive officer of Antares, said in a statement.

Upon completion, Halozyme expects a strong balance sheet with less than 3.5x net debt-to-EBITDA ratio at the time of transaction close this ratio is expected to decrease after consummation.

The reverse triangular merger has been unanimously approved by both companies respective board of directors.

The April 13 deal is subject to customary closing conditions and expected to close in the first half of 2022.

Antares is represented by Skadden, Arps, Slate, Meagher & Flom LLP and its financial advisor is Jeffries LLC. Halozyme is represented by Weil, Gotshal & Manges LLP and its financial advisors are BofA Securities and Wells Fargo Securities LLC.

Prior to the announcement, Halozyme and Antares stock was valued at $41.62 and $3.74, respectively on April 12. When it was announced on April 13, Halozyme and Antares stocks were valued at $41.46 and $5.58, respectively. A few days later, on April 18, Halozymes stock closed at $41.74 and Antares stock closed at $5.57.

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Halozyme Therapeutics to Acquire Antares Pharma for $960M, Eyeing its Auto Injector Platform - Law Street Media