Samantha Roberts is three weeks in to a six-week fasting experiment, and she's tired.
She's hungry, she hasn't been sleeping well, and she hasn't lost any weight.
"I feel like I'm trying to change, but I don't think I'm changing for the better," she says.
"I think I'm meaner. I think I'm shorter with people. I'm not as happy as I used to be."
Samantha's experience is not uncommon; manydiets bringwith themmoments of hopelessness and frustration, especially when you're required to overhaul ingrained habits.
Supplied: Samantha Roberts
Under the guidance of dietitian Joanna McMillan and an expert team, Samantha is one of five people participating in a Catalyst fasting experiment, looking at intermittent fasting's impact on weight loss, ageing, gut bacteria, and metabolic health.
She is doing the 16:8 plan.
"I don't eat from 8 o'clock at night till 12 midday the day after, so I fast for 16 hours," Samantha explains.
"Mornings I have black coffee, I'm allowed black coffee, black tea. But just no food.
"I'm getting there [but] maybe I didn't realise what I was getting myself in for."
Samantha's husband Kevin is also participating in the experiment, but he's on the 5:2 diet.
Kevin must eat a healthy diet for five days but cuthiskilojoules down to 2,500 on Tuesdays and Thursdays that's less than a quarter of his regular intake.
Unlike Samantha, he starts to lose weight immediately.
"I managed to pull an extra notch on my belt for my pants, so that's an inch down on my belt size," he says.
"I'm happy to carry on."
ABC: Catalyst
The research into the effectiveness of fasting diets "really is in the early days," but Dr McMillan is hopeful that her experiment will show the benefits of fasting reach beyond weight loss.
"We're so obsessed with weight in this culture, we talk about diet in terms of just weight loss. But [diet] is about what we eat and its impact on our whole body," she says.
"What the research seems to show is that, at least in the short term, fasting is at least as effective as a traditional calorie-controlled weight-loss diet.
"But if we only look atfasting as a weight-loss trend, we demean the research we do have into fasting."
Early studies have shown that in as little as fourweeks, switching from the fed to the fasted state can relieve health issues from inflammation to arthritic pain to asthma, start cellular repair, and increase longevity.
Eating plans that prescribe when to eat, and less so what to eat, are having a big moment. But is there evidence to support this approach to eating and if so, which method is best?
But one area Dr McMillan is particularly interested in is fasting's impact on metabolic health things like the body's blood glucose and insulin levels.
"Metabolic health [refers to] the way your internal body systems are working, and if they're working effectively," she explains.
"If your metabolic health is out of whack it could mean your cholesterol is running high, or your glucose levels are high.
"It's a catalogue of things that lead to poor health.
"Weight is a symptom, not the measure."
Both Samantha, 49, and Kevin, 52, have "harmful levels of fat around their organs, and show signs of elevated blood sugar and insulin resistance".
"If they do nothing, they're likely to have type 2 diabetes within a decade," Dr McMillan says.
"The question for [them] is, can fasting help to get your body responding better to insulin?
"We want to get your body responding better."
Dr McMillan says that one of the benefits of a fasting diet, be it the 5:2 or the 16:8, is that it gives structure to eating and puts a stop to snacking.
"We are in a food environment that we've never been in before, and this is really the first time in human history we've been in this situation, where so much food is available to us all the time," she says.
"So this fasting method at the very least stops that eating after dinner."
Kevin is already worried that his eating habits are catching up withhim.
Before the experiment started, he'd typically drink a case of beer each week, and often pick up a bacon and egg roll or a pie on his way to work as a butcher.
"I wanted to give fasting a go because of my appearance, my body.I'm getting a bit bulging around the torso," he quips.
ABC: Catalyst
For Samantha, a hairdresser, her eating patterns are all out of whack thanks to being on her feet with clients all day.
"Sometimes I don't realise that I've actually eaten because I'm so busy," she explains.
"I eat and then I don't think I've eaten and then I eat again and then I realise I did eat, but I'm so busy that I forget.
"I do have a mirror in front of me all day, but I don't actually look up at me. It's a shock when I see me."
The hope is that six weeks of an intermittent fastingdiet will helpKevin and Samantha eatmindfully.
"What we certainly know is that getting your calories down is beneficial, and this is another option," Dr McMillan says.
"After dinner, the kitchen's closed.It simply stops that snacking that you tend to eat while you're on the sofa."
But intermittent fasting isn't just about going without it's also about choosing nutritious food when you can eat, to provide lasting energy to get through the fasting window.
Diet quality is critical to the success of intermittent fasting diets, says lifestyle disease specialist Sam Hocking.
"I think one of the things where people can go a bit wrong with these diets is that idea of doing the 5:2 [and thinking], 'there are two days where you have to restrict your calories but on the other five days you can eat whatever you like'.
"You can't have the day where you're partying all day and eating and drinking and then expect to get the benefits.
"You've got to eat healthily on the normal eating days."
Supplied: Samantha Roberts
For Samantha and Kevin, this means stocking their pantry with lots of wholegrains, fruit and veggies, nuts and seeds, lean meats, and avoiding processed meats and snacks.
It also means restricting alcohol.
"As of last week, I drank approximately 48 bottles of beer less than what I'd normally consume," Kevin laughs.
"The things that I've been eating differently are pumpkin, tofu, couscous, and sweet potato chips. [I have] just small pieces and other things mixed in with my other vegetables.
"I'm loving it, it's just the food I've got to eat to get where I want to be."
In the first six weeks, Samantha findsit'ssometimes hard to incorporate thechanges into her grocery shop, even though she has meal plans and expert advice.
"I'm just trying to manage everything," she says.
"To make sure I've shopped, to make sure I've got enough vegetables, to make sure I've got enough plant-based stuff.
"[I have] to be really organised I have never spent this much time in my kitchen. I'm always cleaning the kitchen 'cause I'm making so much stuff.
"It's a whole lifestyle change."
Supplied: Samantha Roberts
On the 16:8, another challenge Samantha faces is waiting until midday to eat.
"There's no talk about food, it's banned. Till 12 o'clock," she says.
"It's quite hard hitting I think, more than I thought it would be. If I'm up at 5.30, it's six-and-a-half hours with no food. It's a long time.
"From 12, I'll try and have some eggs. And then at like 1, I'll try to have lunch, and then I'll have fruit a lot more."
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One thing she has to watch is "panic eating" in the minutes before 8:00pm.
"I think I have a personality, if somebody says you can't have that water, then I want it even more. I think my personality is like that, but I think it's a sense of panic," Samanthasays.
"[I think], 'What else am I going to cram in before 8 o'clock?'.
"The worst thing is, I actually don't feel like I need something else to eat, but I'm eating it because if I don't, I'm not going to eat until tomorrow again."
Kevinacknowledges "it's more tricky for Samantha than for me".
"She's finding it hard in the mornings to not eat till 12 o'clock," he says.
"She wakes up early, she starts to stress out a bit, I think and gets a bit frustrated."
But Samantha is determined to stick with the plan.
"My expectations were pretty high, but at least I've done something, and I'm still doing it," she says.
Supplied: Samantha Roberts
After six weeks of participating in the fasting experiment, Samantha and Kevin settlein to their fasting patterns, and committo sticking to themfor a little while longer.
Their cravings abate, theybecome more comfortable with feeling hungry, and there are no bad foods in the pantry.
"[It was] totally a positive experience, I've enjoyed it I know I've whinged. I have whinged a lot," Samantha says.
"I feel better. I know [when] I don't want to eat, I'm happy just to leave it at 8 o'clock.
"As long as I prep, I'm finding it better, even if I can't find time for shopping.
"As long as I've got the vegetables and fruit at home, we're good."
ABC: Catalyst
WhenDr McMillan conducts her final tests to see how Kevin and Samantha have tracked, the results "are a little unexpected".
Over the six weeks, Samantha lost 3.5 kilogramsand Kevin 8.5 kilograms but Kevin's weight loss is actually "some cause for concern".
"More than half of Kevin's weight loss came from lean body mass most of it [was] muscle," she says.
"Lean muscle [is] crucial for staying healthy as we age. So, going forward Kevin and anyone taking up fasting needs to ensure they also do exercise."
There has also been little change toSamantha and Kevin's gut health.
Butthere has been "a really big metabolic improvement" for them both.
In particular, Samantha's fasting insulin levels reduced, and her fasting blood glucose levels came down to "the normal category", which meansshereduced her risk of developing type 2 diabetes.
Supplied: Samantha Roberts
"This is a really powerful message, because you haven't actually lost a lot of weight, but you've seen that really big metabolic improvement," Dr Hocking says.
"Even for someone who doesn't lose any weight, if your metabolic health has improved because you're eating better and you're exercising and getting enough sleep, you're in a far healthier position."
Dr McMillan says Samantha "epitomises the promise of fasting for me".
"She has managed to overcome a really tough journey through my experiment and embrace a new way of eating," she says.
While the results of Dr McMillan's intermittent fasting experiment are promising, she warns thatfasting is"not a magic bullet" for weight loss or overall health.
It's also a method that should not be overdone;fasting for too long "stresses your body too much".
"Fasting is one tool in the toolkit one potential option to add," Dr McMillan says.
More here:
From 5:2 to 16:8, do intermittent fasting diets work, and what are the challenges? - ABC News