HEALTHY CHOICES: Cambrooke Therapeutics co-founder Lynn Paolella with low-protein hamburger buns produced at the company's Ayer plant. See video at sentinelandenterprise.com. SENTINEL & ENTERPRISE / JOHN LOVE

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AYER -- A marvelous thing happened after a jeweler, her architect husband and her businessman brother put their heads together.

"We made a difference," Lynn Paolella said. "It really started with an inspiration to feed my kids."

Lynn and her husband David have three children. The two youngest, Cameron and Brooke, were born with a rare disease, phenylketonuria, or PKU.

The only way to manage the disease that can cause intellectual disability and other health problems is a diet that minimizes exposure to phenylalanine, an amino acid in protein, yet provides enough protein for the body.

The amino acid is present in many foods, even things like potatoes. It is also a main ingredient of the sweetener Aspartame.

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Until 2009, the accepted treatment for the disease was based on synthetic protein without phenylalanine. "They protected our kids' brains," David Paolella said, but the diet was unpalatable.

Lynn set to work, developing recipes that her children would want to eat. "I love to cook and I absolutely loved the challenge of this low-protein diet," she said.

In 2000, those early attempts led to a new business, Cambrooke Therapeutics. It started out as a family business with just the Paolellas and Lynn's brother, Don Patterson. They developed the food, outsourced manufacturing and made connections all around the world.

Now, the Ayer-based medical food manufacturer is increasingly automated with clients across the globe.

Development of PKU treatment is covered under the Orphan Drug Act, David Paolella said. The act covers drugs and treatment for diseases affecting small numbers of people.

PKU, an inborn error of metabolism, occurs in about one in every 10,000 births in the United States. When caught at birth and managed successfully, the children can thrive. If left untreated, mental retardation results.

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The disease is easy to catch in newborns. The screening test for was developed by a Massachusetts doctor, Robert Guthrie, in the 1960s. His photo is on the wall of the ground floor conference room in Ayer.

Cambrooke is at the cutting edge of medical nutrition. In 2009, the University of Wisconsin Madison developed a way to make a protein without phenylalanine from whey, a cheese-making byproduct.

"They approached us," Lynn Paolella said.

The protein tasted better than the synthetic product. Cambrooke licensed the technology. A peer-reviewed study funded by the National Institutes of Health and the Food and Drug Administration, proved the safety and effectiveness of the protein.

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Along the journey, the company worked with the Small Business Development Center at Clark University in Worcester.

They moved into a former electronics plant in Ayer, drawn to the area by the other beverage and food companies. The building required a multi-million dollar makeover to become a sterile place to manufacture and package beverages.

Food is made from scratch in Brockton, Lynn Paolella said.

The liquids products are put into sterile packaging, David Paolella said. The product will not spoil at room temperature. Nutrients in the liquid will degrade over time.

Their equipment is the only setup in the county that can turn out cost-effective, sterile packages in small batches of 20 to 30 cases, he said. Most beverage manufacturers will produce the same product for days before changing.

Cambrooke makes food products for other inborn error of metabolism diseases. They also make high-fat food that can manage and sometimes even cure intractable epilepsy that is not controlled by drugs.

The products allow people who must follow strict diets in order to remain healthy the chance to live a life just like everyone else.

"In essence, we're a grocery store of products they can eat," David Paolella said. Some want flour to make cookies, others would rather have cookie dough to bake and some want packages of cookies.

When Cameron and Brooke, now 24 and 19, their older brother Bryce, 26, sit down to eat with the family, everyone might eat Cambrooke products.Or maybe not. (The PKU diet is vegetarian; mom and dad like their meat.)

Three hospitals where families are sent when after receiving a diagnoses of a disease that can be treated by diet are in Massachusetts. They go home with information about Cambrooke after their first visit.

Working with the Massachusetts Export Center and the U.S. State Department, Cambrooke established overseas markets. The incidence of PKU is higher in other countries.

They just met with a Chinese mother, who began manufacturing PKU-friendly food after her child was diagnosed. Until recently, if a child in China had PKU, there was no government help. Babies were left by the side of the road to die, Lynn Paolella said.

An export deal could be in the works. The market would be huge. The disease is more common there than it is in the U.S., she said.

The test kitchen, with two sinks, large ovens and seating for a crowd, sees everyone from groups of dieticians to families learning to deal with the restrictive diet. A playroom upstairs keeps little ones busy while older folks learn.

Enabling people and families to live with the diagnoses is another challenge Cambrooke took on.

Some of the diseases treated by diet must require lifelong management. An iPhone app helps patients keep track of their nutrition.

Cambrooke can bill insurers directly, making it easier for their clients.

Schools are required to supply special diets when needed. The school lunch program Lynn Paolella developed is used in about 400 schools, the closest one in Groton.

The meals need to be heated up and the child with a restricted diet can eat with friends.

Health-care benefits are not consistent across the country, David said. Some states do not even require newborn testing for PKU. The test might be sent out of state to be read. If the lab will includes PKU results, out-of-state health-care providers might not give them to parents.

Lynn went to Washington, D.C., to advocate for the Medical Food Equity Act, requiring insurance plans to cover formula and low-protein foods. The act died in committee.

The business remains a family business at heart. Bryce Paolella helped with developing a new product.

Lynn and David Paolella are the founders and work with the company daily.

Don Patterson is the vice president of operations.

Lynn and Don's mother gives the products her own blessing. Marilyn Patterson helps out with packaging; she plants a kiss and a prayer of goodwill in each box she prepares.

Follow Anne O'Connor on Twitter and Tout @a1oconnor.

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For lives at risk, the perfect recipe - Sentinel & Enterprise

Does eating fat make you fat? Thats the question nutritionists asked and answered in the 1970s. The determination was yes, fat clogs your arteries, and for the last 50 years, USDA Dietary Guidelines for Americans have reflected this belief.

Over and over again, Americans were told to reduce their consumption of saturated fats and increase their intake of fruits, vegetables and whole grains. Yet, Americans today are sicker, fatter and unhappier now than ever before.

Were the experts wrong? Its becoming increasingly clear that they were, but you wont hear them admit it anytime soon. After all, careers and reputations are at stake, so lets stick to the course, drumming the same nutritional mantra in the hope that Americans will finally just eat less and lose the weight.

That same old advice has become tiresome, and it looks like beef may soon return as a hero to the center of the dinner plate.

A recent article featured on the Observer titled,Health authorities continue to fail us, writer Pete Ross explains how consumers are ditching 50-year-old nutritional advice that was based on faulty science and are opting for a diet that includes plenty of saturated fats from meat.

Ross writes, Research conducted over the last 30 or so years reveals there is no evidence the consumption of saturated fats causes heart attacks or strokes; cholesterols role in developing heart disease is actually much more complex than weve beenled to believe. In fact, despite constant protests from nutritionists and government authorities, the research actually shows that low carb diets are significantly more effective than low fat diets. And yet, the governments dietary recommendations have changed very little.

Much of the nutrition research occurring even now is still muddying the waters. For example, we hear so often thatred meat is bad, but it is almost always studied alongside processed meats and the results extrapolated for both. Look at any study and the actual line is red and processed meats. On what planet is it reasonable to consider a piece of salami, cured with nitrates and other preservatives, in the same category as unadulterated, grass-fed steak?

The media certainly has their place in our current predicament as well. When it comes to nutrition, they dont care what data and research is reliablethey care about whats going to give them a great headline and arouse emotion in readers. Who could forget in late 2015, when the WHO announced bacon and other processed meats as a level-one carcinogen in the same category as cigarettes?

The news immediately broke everywhere that bacon was as bad for you as cigarettes, when the reality is that 50g of bacon a day is going to increase the absolute risk of cancer by a 0.01 percenthardly something to get worked up over. Unfortunately, the headline, Bacon isnt too great for you as we all suspected, so dont eat it too often, isnt as good as, Bacon is in the same category of carcinogen as cigarettes, so eating it gives you cancer!

Theres an undercurrent of change happening in nutritionists circles, and Im very excited about the opportunities this presents for U.S. beef producers. With some effort, we could soon see ribeye steaks touted as a health food. And no longer would the consumer have to feel guilty about consuming a juicy cheeseburger. Athletes will be grabbing beef jerky as their preferred workout fuel. And pot roasts will be the go-to healthy diet meal for busy families.

We have a serious opportunity to capitalize on this growing momentum, but its going to require some strategic rebranding and a fundamental change in consumer thinking. Its time for our industry to get to work;our consumer is seeking this information. Are we ready to give it to them?

The opinions of Amanda Radke are not necessarily those of beefmagazine.com or Penton Agriculture.

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Case for beef in a healthy diet gains momentum - Beef Magazine

Our immune system functions throughout our body. It is composed of specialized cells that prevent or limit infection in our bodies. Immune cells recognize substances that enter our bodies and attempt to remove them if the substance appears to be harmful to us.

Consuming a healthy diet is one of the best strategies for having a healthy immune system. Research has shown some nutrients; including protein, and certain vitamins and minerals, have specific roles in immune health. If we lack any of these nutrients, our ability to fight infection can decrease.

Protein is found in every cell, tissue and organ in our bodies. When we don't get enough protein, our bodies may produce less certain immune cells and increase our susceptibility to infections of the respiratory, gastrointestinal and urinary tract. Protein foods include chicken, beef, fish, pork, eggs, peanut butter, milk, beans, seeds and nuts. Adult women should get about 46 grams of protein per day. Men should get about 56 grams.

Vitamin A keeps skin and tissues of mouth, stomach, intestines and respiratory system healthy. These tissues serve as our first line of defense against infections. Good sources are carrots, apricots, sweet potatoes, kale, spinach, red bell peppers and eggs.

Vitamin C helps the formation of antibodies and the production of certain immune health. Food sources include citrus fruit, papaya, strawberries, kiwi, tomatoes, and foods such as cereals fortified with Vitamin C.

Vitamin E protects cell membranes in the body. For vitamin E you can eat sunflower seeds, almonds and oils such as sunflower and safflower oil.

Selenium deficiencies have been shown to decrease immune cells' disease fighting power. It is a mineral found in the soil. You can get selenium for the animals and plants that we eat.

Vitamin D is important to fight off infection and disease. The best way to get vitamin D is to absorb it from the sun. Adults need 600 IU of Vitamin D each day. Good sources include milk, oily fish such as tuna, mushrooms, breads, orange juice and yogurt.

Vitamin B6 is important for immune cell growth. You can get it from tuna, turkey, beef, chicken, salmon, sweet potatoes, sunflower seeds and bananas.

Iron deficiency has been associated with reduced immunity in human and animal studies. Our bodies absorb it better when it is paired with foods high in vitamin C. Food sources include: red meat, pork, poultry, beans, spinach, iron fortified breads, cereals and pastas.

Zinc deficiency can affect how certain immune cells function. Eat lean meat, poultry, seafood, milk, whole grain products, beans and nuts.

To have a healthy immune system, we need to focus on getting healthy overall. Here are a few lifestyle factors that can impact your immune system.

Exercise Participate in regular physical activity. It allows your immune system to work properly.

Manage stress Certain types of stress weaken the immune system, and make it harder to fight infection.

Get enough sleep Sleep deprivation can depress the immune system's disease fighting power by reducing the production of T cells.

Limit alcohol It is one substance that can suppress our immune system. If you drink, drink in moderation.

Take steps to fight infection Wash hands often. Practice good food safety. Wash fruits and vegetables before eating. Thaw foods safely. Cook meat and seafood thoroughly and keep raw and cooked foods separate.

Source: North Dakota State University Extension Service

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Health for your immune system - Weatherford Democrat

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WESTON, WV(Marketwired February 23, 2017) The physicians and researchers at Diet Doc medical weight loss are urging consumers to choose wisely when it comes to weight loss strategies this year. Certain diets are gaining popularity due to an enormous internet presence, which leaves little room for proven, researched based weight loss strategies. This can lead many individuals to make unsafe dietary choices simply because a fad has allegedly produced satisfactory results for other dieters. The hGG diet is a prime example of this. Produced during pregnancy, the human chorionic gonadotropin hormone (hCG) is purported to stimulate weight loss in conjunction with a calorie restrictive diet plan (only 500 calories per day are to be consumed). Supporters claim that HCG injections, drops or tablets target and eliminate long-stored fat reserves within the body. Over the past few years, the marketing and promotion of the hCG diet for weight loss have grown astronomically on the internet and the vast majority of the information on hCG and its corresponding products offered online are designed to confuse and make profit from an unknowing public. The truth, is that the medical industry has never supported the hCG diet. In fact, since its emergence in the 1950s, it still has yet to be deemed effective, or safe by any reputable medical organization.

Consuming a mere 500 calories per day can lead to health problems and since hCG isnt FDA regulated, most online retailers are selling products that contain little to no hCG. Therefore, any quick weight loss that occurs from the hCG diet is due to starvation dieting. There are claims that hCG is a permanent cure for obesity and that patients who on the hCG diet are losing two pounds of fat per day. However, any legitimate weight loss expert knows that starvation dieting is dangerous and can cause more harm than good. Rapid muscle loss, excessive bloating, binge eating, weight rebounds, poor nutrition and low-energy are just a few of the potentially negative side effects of such diets. Lastly, many existing websites claim that hCG permanently resets the metabolism. But experts suggest that any method one utilizes to lose weight, whether it be diet, exercise or gastric bypass surgery, once the weight is off long-term, a consistent weight maintenance regimen must be implemented to keep the weight and health in check.

Diet Doc wants consumers to know that there are in fact, many other safer dieting strategies for weight loss which are more effective than the severely restricted diet. The best options will be those which offer nutritional support and doctor supervision throughout the process. Dr. Rao, Medical Director of Diet Doc states that, Weight loss goals can be met by the development of specific nutrition plans, dietary supplements and guidance to ensure that body composition changes are optimal for each individual. Diet Doc also offers their clients unlimited access to nutritional coaches and weight loss experts by phone, which means no traveling to weight loss centers for weigh-ins and prescription pickups. Dedicated patients can follow Diet Docs guidance and start safely losing up to 20 pounds per month.

New patients can get started immediately, with materials shipped directly to their home or office. They can also maintain weight loss in the long-term through weekly consultations, customized diet plans, motivational coaches and a powerful prescription program. With Diet Doc, the doctor is only a short phone call away and a fully dedicated team of qualified professionals is available six days per week to answer questions, address concerns and support patients.

Getting started with Diet Doc is very simple and affordable. New patients can easily visit https://www.dietdoc.com to quickly complete a health questionnaire and schedule an immediate, free online consultation.

About the Company:

Diet Doc Weight Loss is the nations leader in medical, weight loss offering a full line of prescription medication, doctor, nurse and nutritional coaching support. For over a decade, Diet Doc has produced a sophisticated, doctor designed weight loss program that addresses each individual specific health need to promote fast, safe and long term weight loss.

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Diet Doc Reminds Consumers that the hCG Diet is not a Viable Weight Loss Strategy - Satellite PR News (press release)

But Karen Jarchow, who primarily played softball throughout high school and never tackled endurance sports of any kind until her college years, has managed to climb to the top of the world in the sports of mountain bike and fat bike racing.

Jarchow, a 2003 Luverne High School graduate and the daughter of John and Kathy Jarchow, Luverne, won the 2016 National Ultra Endurance Mountain Bike Race Series Championship.

More recently, she claimed the womens title in the Fat Bike World Championships on Jan. 27 at Crested Butte, Colo.

How did Jarchow, a native of southwest Minnesotas prairie lands, become an elite cyclist by age 32? And what drove her to make the Rocky Mountains her adult home?

Following high school, Jarchow, who has two older brothers, attended Minnesota State University, Mankato, where she earned a degree in athletic training (with an emphasis in psychology and corporate and community fitness) in 2007.

First it was the notable hills arising out of the Mankato river valley that challenged Jarchow.

I had a pretty heavy academic schedule, but I took a swim class, ran and got my first road bike then, said Jarchow of her college years.

I used to ride my bike to get groceries or run errands, and I remember there was always a big hill to climb on the way home. Countless times, people pulled over to ask if I needed a ride, she laughed.

Having been diagnosed with scoliosis as a child, Jarchow cited the condition as a catalyst of sorts.

That motivated me to be more proactive about my health, because it was even more important to be active and grow strong and flexible in all the right places, Jarchow said.

Colorado was on Jarchows radar since she was 8 years old. At that time, an aunt, Ellen, moved there, and the family began visiting her regularly in the Centennial State.

I also had done some job shadowing at a hospital out there, and when I graduated from college, I got a job as a physical therapy assistant at a hospital in the Vail area, Jarchow said.

I loved the mountains.

Jarchow had intended to begin studies toward a physicians assistant degree after a couple of years.

I even had a school picked out in Denver, she said.

Instead, Jarchow tried mountain biking in 2010 and her focus changed.

I quit my job at the hospital and jumped on the mountain town routine of having multiple jobs to earn enough money to enjoy where youre living, she explained. I played that game for a while, but then I moved out to California for a cycling job.

In California, Jarchow managed a womens bike shop boutique. Fortuitously, her work put her in email contact with a man, Jeff Kerkove, who happened to live in Colorado. It was clear they had much in common, even with hundreds of miles between them.

Then I moved back to Colorado I missed it so much and one thing leads to another, said Jarchow.

In September 2016, Jarchow and Kerkove were married in a forest park near Vail, with many friends and family members present to witness their nuptials.

The funny thing is, Jeff grew up in Algona, Iowa, and has a grandma who lives in Pipestone, said Jarchow. We figured out that he had driven by my familys farm for 18 years whenever his family was visiting his grandma.

Jarchow laughs about it today, but her early efforts at mountain biking wereup and down.

Technically, in my first season of racing, I went from beginner to pro level over the course of a summer, related Jarchow, who has now been competing at a national professional level for four years.

Not long into her first racing season, she had a dangerous crash, hitting a stand of sagebrush and hurtling headfirst off her bike.

I nearly broke my neck and I had a serious concussion, reported Jarchow. Racing-wise, that was it for the season, but I was back riding as soon as I was allowed to; I just loved it, and that incident made me extremely motivated to figure out the whole bike-handling thing.

Mountain bike racing isnt for the faint of heart; by Jarchows tally, shes suffered three or four concussions over time (The first was the most serious, she pointed out), and bruises and scrapes just come with the territory.

Jarchows Luverne upbringing has aided her along the way. Her father, an able mechanic who works in animal nutrition, made sure Jarchow and her brothers possessed certain basic skills.

You have to be very self-sufficient on a bike, and your first goal is always to finish a race, Jarchow said. So you have to be able to fix a flat tire or broken chain if that happens during a race, and my dad taught me how to take care of my stuff.

To stay in tip-top condition Jarchow is 54 and aims to maintain her weight between 108 and 112 pounds she chooses to eat very clean, all whole foods, no dairy, no gluten, a good whole-seed, plant-based diet for the most part, she reported.

When youre racing, you can be on the bike for three to five hours, eating sugar the whole time for energy, so I dont make processed foods or sugar a part of my regular diet, she noted.

Shes calculated a need for 250 calories per hour during races, which she consumes in the form of GU Roctane Energy Gel alternated with water and energy chews.

Theyre basically electrolyte-filled gummy bears, she said of the energy chews.

Before a race, theres usually time to scope out the trail and course, so I have it in my head when I can grab food from a pocket or take a drink from a bottle, depending on the courses difficulty. Then, on the fly, if theres a break in the trail and I can take a hand off the bar safely, I do it.

Usually, Jarchow trains from 10 to 20 hours per week, incorporating a combination of bike, yoga and gym routines.

I take a month or two off each year to do whatever I want, but Im always still on the bike, she said.

With evidence pointing to the fact that women dont peak until age 35 in endurance sports, Jarchow feels she is finally coming into her own.

Last year was my break-through season, when I won the National Ultra Endurance Series, she shared. That involves marathon races of anywhere from 50 to 70 miles on mountain bikes, and the races took place in Utah, South Dakota, Colorado and Wyoming.

Fat biking is not as recognized, but its starting to gain momentum, she observed. Mountain biking is what I focus on, and fat biking allows me to stay outside on a bike in the winter months.

Jarchow not only stayed on the fat bike she conquered the field at the Jan. 27 Fat Bike World Championships, at which 300 racers competed. She was the female champion, clocking two hours and four minutes on the 27-mile course, and the eighth overall finisher.

My time was 13 minutes ahead of the next woman racer, and she was last years female champion, reported Jarchow.

On race day, the temperature was 26 degrees below zero when Jarchow and Kerkove woke up. When she started the fat bike course, the temperature had moderated to eight below zero.

Honestly, I was worried about the cold, but Jeff had done an extremely long fat bike race earlier in the winter that was also very cold, so I had all the little tips from him to keep my fingers, toes and face warm and frostbite-free, she confided.

By the second lap I was able to take off my outer jacket.

Typically, Jarchow says she might face 10 to 15 female competitors in mountain bike competition, depending on the race.

Its not like being a professional football player; theres not really a lot of money in mountain bike racing, but we have sponsors who cover some of the costs and the prize money is a nice perk, but its definitely not something to rely on, she assured.

Jarchow exclusively rides Canyon bikes.

Canyon is a German-based company, but theyre coming to the U.S. by the end of the summer, she said.

Jarchow and Kerkove are both members of the U.S. Team Topeak-Ergon.

Jeff works in customer service and marketing for Ergon, one of our title sponsors, and my full-time job is doing PR for Ergon and a handful of other cycling brands, she said.

Jarchow shares her love of mountain biking with a younger generation. A few years ago, she co-founded Vail Valley Alternative Sports Academy, a mountain biking camp for kids ages seven to 13.

Each session is a month long, during June and July, for two days a week, she listed. We work with 60 kids at a time.

What we really wanted was to create a program that promoted stewardship of trails, and that emphasizes the fun of the sport versus just the competitive side. Its been a great success, and we sell out every summer.

Jarchow and Kerkove make their home in Eagle, located about 30 miles west of Vail and 30 miles east of Glenwood Springs.

Its a great place for kids to learn mountain biking because they can progress from rolling terrain to big mountain loops, and they can learn to ride safely and correctly, she stressed.

Now that Jarchow is established in Colorado and making a living that stems from her love of mountain biking, she thinks her parents are okay with the path her life has taken.

At first, they were very concerned because they didnt understand what I was doing, she revealed. Now theyve seen how Im integrated into this community and winning races, but it has to be scary for a parent to see a kid go into an area they dont know anything about.

It can be dangerous, too, and at one point my mom told me to stop telling her what I was doing.

That included other extreme sports, such as rock climbing, skiing, snowshoeing and dirt bike riding.

Among area supporters who admire Jarchows success and determination are a few of Jarchows aunts and uncles and their families: Tim and Kayla Jarchow and Mike and Wanda Jarchow, all of Luverne, and Gina and Rob Newman of Wilmont.

Gina Newman, Jarchows aunt, says her triplet daughters (Worthington High School juniors Brianna, Jamie and Kelly Newman) think their older cousin is pretty cool.

Were very proud of her accomplishments, said Newman. She definitely didnt choose a traditional course. I still picture her as a little girl visiting me in my college dorm, but shes really accomplished a lot and done so well with it.

Jarchow, in turn, looks up to Canadian mountain biking champion Catharine Pendrel.

Catharine is not only a strong competitor but also humble, kind and approachable, recommended Jarchow. Shes very inviting and supportive of other women in the sport, and thats always something to strive for.

As Jarchow anticipates the coming season, she says shes feeling stronger every year, even as she knows that competing at her current level isnt something she can do for decades.

But its important to always have something to be driving for, emphasized Jarchow. Id like to be in the top five in the Epic Ride Series this year.

Im always looking at the next goal; I never really settle.

Read more from the original source:
Luverne native succeeding as professional mountain bike racer - Daily Globe

Enlarge / These mice are about to have issues.

In mice with either type I or type 2 diabetes, an intense, four-day fasting diet seemed to regenerate pancreas cells and restore insulin production. Researchers reported this finding on Thursday in Cell.

In Petri dish experiments, human pancreas cells from patients with type 1 diabetes also showed altered gene expression and kick-started insulin production after being exposed to blood from people on a fasting diet.

The results of the early work are promising for potential dietary treatments of both types of diabetes. Type I is caused by a loss of insulin production, while type 2 is caused by diminished production or insensitivity to insulin, a hormone that triggers the breakdown of sugar in the blood.

But the research needs to be verified. Far more work in humans needs to be done before researchers can make any sort of conclusions or treatment recommendations. Experts warn that trying out the diet could trigger dangerous complications in diabetic patients.

It boils down to do not try this at home, Dr. Valter Longo, lead author of the study and a researcher at University of Southern California, told the BBC. This is so much more sophisticated than people realize.

The mice were given a low-calorie, low-protein, low-carbohydrate, high-fat diet for four days. On the first day, the mice could only eat 50 percent of their normal calorie intake. For the remaining three days, the mice ate just 10 percent. Next, they got up to 10 days of normal eating, which allowed them to regain lost weight, before another four-day fast. The mice went through this cycle three times.

Mice that model type I diabetes saw a boost in their pancreatic beta cells, which generate insulin. In mice modeling type 2 diabetes, researchers saw restored insulin production and reduced insulin resistance.

"This is good science and does give promise for the future treatment of diabetes, immunologist Anne Cooke of the University of Cambridge told the NHS. But we need further studies to see whether this works in people as well as it has in mice."

Cell, 2017. DOI: 10.1016/j.cell.2017.01.040 (About DOIs).

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A fasting-diet may trigger regeneration of a diabetic pancreas - Ars Technica

Home General Health Bladder Nephrotic syndrome (a kidney disease): Causes, symptoms, treatment, and diet

Nephrotic syndrome is a kidney disorder that results from the release of too muchprotein in the urine. When damage is caused to the blood vessels within the kidneys, which filter waste and water, it can lead to nephritic syndrome. Nephrotic syndrome leads to swelling of the feet and ankles, along with other health conditions as well.

To treat nephritic syndrome, its important to treat the underlying health issue causing it. Because nephrotic syndrome can lead to other complications, its important to begin treatment right away.

Damage to the blood vessels, which filter water and waste, is the primary cause of nephrotic syndrome. When these vessels are healthy they keep the appropriate amount of protein in the body and expel the extra. When they are damaged too much protein leaves the body through the urine.

There are many causes of blood vessel damage, including:

Symptoms of nephrotic syndrome include:

The factors that increase your risk of developing nephrotic syndrome include kidney damage due to medical conditions like diabetes or lupus, use of medications like nonsteroidal anti-inflammatory drugs, and infections like HIV, hepatitis B and C, and malaria.

The complications that may arise due to nephrotic syndrome include blood clots, high cholesterol, poor nutrition, high blood pressure, acute kidney failure, chronic kidney disease, and an increased risk of infections.

There are three main ways to test and diagnose nephrotic syndrome: urine test, blood test, and kidney biopsy. A urine test will reveal abnormalities found in the urine including protein. A blood test will reveal low levels of protein and high levels of cholesterol, and a kidney biopsy will take a small tissue sample from the kidney and test it.

Treatment for nephrotic syndrome involves treating the underlying condition; therefore, treatment may include:

Its important to change your diet if you have nephrotic syndrome because unhealthy foods can further damage the kidneys. For starters, choose leaner sources of protein or even plant-based protein; it isnt as taxing on the kidney. You will also want to reduce the amount of fat and cholesterol in your diet to control cholesterol levels and reduce your risk of heart disease, which can worsen nephrotic syndrome. Lastly, reduce your salt intake to minimize swelling.

http://www.mayoclinic.org/diseases-conditions/nephrotic-syndrome/basics/complications/con-20033385

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Nephrotic syndrome (a kidney disease): Causes, symptoms, treatment, and diet - Bel Marra Health

Women's Health

'I Lost 30 Pounds After Trying The Whole30 DietHere's How I Did It' Women's Health I would try a new workout, do it for two weeks straight, and not work out again for another three months. I was the same way with my diet. I'd eat salad and smoothies for a week before a trip to Vegas, but then I'd go right back to the junk the week ...

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'I Lost 30 Pounds After Trying The Whole30 DietHere's How I Did It' - Women's Health