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Posted: February 15, 2017 at 9:47 pm
Science Daily | Father's diet impacts on son's ability to reproduce, study in flies suggests Science Daily "Our study found that males that were raised on either high or low protein diets, but spent their adulthood on an intermediate diet, produced sons that had large differences in gene expression, which most likely contributed to the resulting differences ... |
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Father's diet impacts on son's ability to reproduce, study in flies suggests - Science Daily
Posted: February 15, 2017 at 9:47 pm
Ethan Miller/Michael Kovac/Getty Images for City of Hope
Dr. Lukeallegedly criticized Keshaabout her weight loss efforts to her managerbehind her back when they worked together, according to emails submitted to a New York court as part ofthe singer's latest efforts to break ties with the producer amid their more than two-year court battle.
Her attorneys included the messages while filingarequest this weekto havetwo record contractsKeshasigned with Dr. Luke invalidated "so she can befree from her abuser and rebuild her physical, emotional, and mental health."
"Kesha and her attorneys continue to mislead by refusing to disclose the larger record of evidence showing the bad faith of Kesha Sebert and her representatives which is greatly damaging to them," Luke's attorney said in response. "It also shows the tremendous support that Dr. Luke provided Kesha regarding artistic and personal issues, including Kesha's own concerns over her weight."
"Rather than agree to a thorough disclosure, Kesha and her representatives improperly publicized, without Court permission, three out-of-context emails which do not present the full picture regarding the events they concern," the attorney said. "Dr. Luke looks forward to full vindication in Court."
Kesha and Dr. Luke's legal battle began in 2014 and has stalled her music career. Shesuedhim in a Los Angeles court in a bid toinvalidateher recording contracts with him,alleging he "sexually, physically, verbally and emotionally abused" her. He denied any wrongdoing. She saidhe calledher a "fat f--king refrigerator" and that his wordsabout her weight caused her to developbulimiaand even attempt suicide.
Luke filed a defamationcountersuitin New York.In 2016, ajudgedenied Kesha'srequest to be allowed torelease musicoutside of Luke'sauthority. Months later, shedropped her sexual abuse claims, while his defamationsuit against her in New York continued.
Her attorneys included in their recent filing anemail exchange from June 2012,which showsLuke allegedly sent Kesha's manager Monica Cornia an email with a link to an articletitled "Global Weight Gain Is WORSE Than Increasing Population!" It is unclear who initiated the conversation.
"She was crying on the way home FYI just for you," the singer's manager wrote in responsehalf an hour later.
"We get concerned when she is breaking her diet plan," Luke allegedly responded. "We have seen it happen multiple times...almost every day...it is also double concerningwhen the A list songwriters and producers are reluctant to give Kesha their songs because of her weight."
"She is working really hard," Cornia said. "And to get in trouble for drinking a Diet Coke and called out in front of the whole room when she's not there is not okay. If she were gaining weight or not losing I would totally get it. Everybody wants her to be the best she can be. But she is still a human being who has feelings and major insecurities and she is doing her very best and I would hope you could be supportive of that."
"Nobody was calling anybody out," Luke allegedly said."We were having a discussion on how she can be more disciplinedwithher diet. There have been many times we have all witnessed her breaking her diet plan. This particular time it happened to be Diet Coke and turkey while on an all juice fast. We just want to see her stick to the plan for herbenefitand the benefit of her career. Please help keep her on her diet. No need to respond any further."
The manager said Kesha "is doing all juice to lose weight."
"If she drinks a Diet Coke and asks to eat turkey and I tell her she shouldn't and she should eat a cucumber," she said. "Then she is doing great and I would hope you'd be supportive and helpful rather than critical. Again, she's human and not a machine. If she were a machine that would be way cool and we could do whatever we want. I will respond if I feel I need to."
"I'm up later than you so I will always get the last word," Luke allegedly replied.
"Let's make a bet," the managersaid.
It is unclear who ended up having the last word in the email exchange.
In another email thread,Kesha's manager writes to her bosses that the singerand Luke had a dispute over lyrics to one of her songs.
"He said, 'I don't give a s--t what you want. If you were smart you would go in and sing it,'" the managerwrote about the producer.
"These emails do not show that the lyrics of 'Crazy Kids' were, in fact, rewritten at Kesha's request," Luke's attorney said. "Any claim by Kesha to the contrary is deceiving the public-just like her other meritless claims of wrongdoing by Dr. Luke."
In their recentfiling, Kesha's lawyers allege that Luke also breached their contracts not only via his "years-long abuse of and physical threats against her," but also due to the"unreasonable and purposeful delay she has experienced in making her new album."
The case is set to continue next week with a telephone conference with the judge.
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Posted: February 15, 2017 at 9:47 pm
Most women complain of gaining weight during and after menopause, especially belly fat that refuses to budge. But a new study published in Menopause, the journal of The North American Menopause Society (NAMS), found that regular exercise can help with worrisome symptoms like hot flashes, and can bring success in the battle of the bulge even in those who had been sedentary.
Researchers studied 234 postmenopausal women aged 45 to 64 years who had been sedentary for at least the previous year. They participated in a 20-week program of exercise, and found they experienced positive changes in both short-term and long-term physical and mental health.
Improvements included better flexibility and cardiovascular fitness. In addition, they experienced significant reductions in weight and body mass, and hot flashes were brought under control.
The results are especially encouraging for women who don't want to use hormone replacement therapy to control symptoms of menopause, and are looking for safe but effective options with no side effects.
"Growing evidence indicates that an active lifestyle with regular exercise enhances health, quality of life, and fitness in postmenopausal women," says Dr. JoAnn Pinkerton, NAMS executive director. "Documented results have shown fewer hot flashes and improved mood and that, overall, women are feeling better while their health risks decrease."
For most women, menopause occurs between the ages of 45 and 55, but according to the Mayo Clinic, the average age in the U.S. is 51.
Several natural remedies have been found to ease the symptoms of menopause. A study published in the International Journal of Clinical and Experimental Hypnosis found that hypnosis relaxation therapy reduced hot flashes.
Acupuncture may also be able to help. A study published in the journal Menopause found that women who underwent acupuncture saw a larger decrease in the number and severity of menopausal symptoms after 12 weeks than women who received a placebo treatment.
2017 NewsmaxHealth. All rights reserved.
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Weight Loss Possible After Menopause - Newsmax
Posted: February 15, 2017 at 9:47 pm
"I have a friend who suddenly, at 40 years old, put on 20 pounds. She was confused, and to be honest, I was toobecause I knew she ate healthfully. Turns out, she had started making granola at home. It was packed with various nuts a smart, antioxidant-rich snack that can also be very caloric. Plus, she was incorporating more fruit into her diet, specifically bananas and grapes, which are high in sugar. I suggested that she swap the granola for almonds (they're lower in calories, as long as you limit yourself to about 10 per day) and the bananas and grapes for a handful of berries, which are much lower in sugar. Within three months, she had lost the 20 pounds she'd gained without making any other changes, and kept it off. Just remember: You can overdo it with even the healthiest foods, so choose wisely!" Amy Rothberg, M.D., Ph.D., director of the Weight Management Clinic at the University of Michigan in Ann Arbor
RELATED:7 Diet Mistakes You're Definitely Making
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7 Weight-Loss Secrets Doctors Tell Their Friends - Redbookmag.com (blog)
Posted: February 15, 2017 at 9:47 pm
NEW CITY Rockland County Executive Ed Day and County Health Commissioner Dr. Patricia Schnabel Ruppert remind residents that February is Heart Month a good time to learn how to prevent heart disease and stay heart healthy.
Heart disease is the leading cause of death for men and women in the United States. The good news is that by living a healthy lifestyle, you can help keep your blood pressure, cholesterol, and blood sugar at normal levels and lower your risk for heart disease and heart attack, said Dr. Ruppert. A healthy lifestyle includes eating a healthy diet, staying at a healthy weight, getting enough physical activity, not smoking or using other forms of tobacco, and limiting alcohol use.
Follow these steps:
People with diabetes have a higher-than-average risk of having a heart attack or stroke. Our free 16-session National Diabetes Prevention Program can help you gain the skills you need to make lifestyle changes to prevent or delay type 2 diabetes, if you are at risk or have been diagnosed with pre-diabetes. The next program begins Wednesday, February 22 from 3 p.m. to 4 p.m. in Spring Valley. Call 364-2651 for more information and to find out if you are eligible to participate.
Ready to lose weight? The Lose to Win Weight Loss Program uses the latest guidelines to help you lose weight safely and successfully. There is a $10 fee due at the time of registration. Call Nyack Hospital at 348-2004 to find out when the next free eight-week program begins.
To learn more about preventing heart disease, speak with your doctor, or visit the American Heart Association website at http://www.heart.org and the CDC website atwww.cdc.gov/heartdisease/prevention.htm
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Take Steps to Help Prevent Heart Disease - Hudson Valley News Network
Posted: February 15, 2017 at 9:47 pm
Its a big temptation, after eating yourself through the holidays, to want to crash diet.
But nutritionists, including Anita Bermann of Bainbridge Island, say that will only lead to more problems.
Bermann, who owns Ideal Feast Nutrition, tells her clients that fad dieting juicing, liquid diets and cleansing can bring on health issues such as anorexia, bulimia, osteoporosis, pancreas problems, heart issues and diabetes.
Radical diets are not sustainable, she said. They dont last. You become weak and fatigued and you go off that diet. Then you begin to feel like a failure.
Instead, she suggests that if you was to lose weight, read the labels on the food you are eating.
Processed food can negatively affect you, Bermann said. Look for fresh vegetables, fruits and lean protein.
She also warned against diets that totally eliminate things like fruit or bread.
On diets where you have no carbs or sugars, you ultimately will begin to crave those things, she said. What you need to do is limit those things and make good choices.
For example, she said, look for whole grain breads. They are healthier and will make you feel fuller faster.
And speaking of that, she teaches something called intuitive eating.
When we are babies we eat when we are hungry, she said. Thats the natural way to eat. As adults, we often eat because the clock says its time to eat.
We need to be in touch with our own hunger and fullness signals.
The focus should be learning how to tell when you are truly hungry and knowing when you are full, she said.
Our bodies are meant to be fueled every few hours, Bermann said. So eating small meals throughout the day can be a way to keep hunger at bay.
When crash dieting happens, the dieter often times doesnt get enough vitamins and begins to feel sluggish.
And they become susceptible to disease and infection because their immune systems is weak, she said.
In order to diet safely, she suggests doing some research first.
If you cant afford to see a nutritionist, look online. Figure out what a balanced diet is for you and how much food intake is safe.
She suggests the Academy of Nutrition website at http://www.eatright.org.
In the first few days of your diet, think about when you truly are hungry and when you are full.
Listen to your body, she said.
As for breakfast being the most important meal of the day, she subscribes to regular meals throughout the day as the most important.
But if you skip breakfast, you are allowing your body to go without food and fuel for too long, she added.
According to the Centers for Disease Control and Prevention, 35.7 percent of adults and 17 percent of children are obese. Obesity puts stress on every part of your body and increases your risk of developing major health problems, including heart disease, Type 2 diabetes, high blood pressure, stroke, liver disease, infertility and sleep apnea.
Type 2 Diabetes: Obesity is one cause of Type 2 diabetes, but another is unstable blood sugar levels. When you consume a lot of refined grains and sugar-rich foods, your glucose levels spike and drop repeatedly. Over time, these dramatic changes in your blood sugar levels can lead to insulin resistance, which is characterized by a decreased sensitivity to insulin. If this condition is not corrected, it can advance to Type 2 diabetes.
Heart Disease: Unhealthy foods are often high in sodium, fat, cholesterol and sugar. Eating these unhealthy foods on a regular basis can increase your blood pressure as well as your cholesterol and triglyceride levels. Over time, high blood pressure and high lipid levels can put a great deal of stress on your heart, increasing your risk for heart attack, stroke and coronary artery disease.
Source: Bermann at http://www.idealfeastnutrition.com, Harvard School of Public Health, Centers for Disease Control
Nutritionists provide these guidelines:
Improper nourishment: Your body needs a certain amount of calories the basic energy unit of the body to function. Almost all foods have at least some calories, but not all foods have the proper nutrients your body needs. Sugary snacks, for instance, are often high in calories, but they are empty calories, meaning they have none, or very little, of the important nutrients, such as vitamins and minerals, that you need. Not getting enough nutrients can result in malnutrition. Mild symptoms of malnutrition include dizziness, fatigue and weight loss. In severe cases, symptoms such as hair loss, fainting and lack of menstruation can occur.
Disease: If you body doesnt get enough of the proper nutrients, particularly antioxidants, your immune system will feel the effects. A weakened immune system makes you susceptible to ailments, such as the flu or common cold. Lack of proper nutrients can also affect your major organs, leading to or contributing to a variety of ailments. For example, one common problem that results from a diet high in sugar and processed carbohydrates a complex form of sugar is that your pancreas can become overworked. The pancreas produces a hormone called insulin, which helps break down sugars in the body. If you body doesnt utilize insulin properly, a diet high in sugars causes insulin production to increase exponentially, which can lead to the pancreas eventually shutting down or limiting insulin production a condition known as Type 2 diabetes. When untreated, Type 2 diabetes often leads to other problems, including fatigue, increased hunger and thirst, blurred vision and erectile dysfunction.
Nutritional deficiency: Most vitamins and minerals are found in whole foods, such as fruits, vegetables and lean meats. Neglecting to include these foods in your diet can lead to nutritional deficiencies.
This article originally appeared in Kitsap Living Winter 2017.
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Eating right: Make sure you stay healthy when you are dieting | Kitsap Living - Bainbridge Island Review (subscription)
Posted: February 15, 2017 at 2:53 am
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All cholesterol is not equal. It comes in healthy and unhealthy forms, and doctors have long advised people to cut back on the bad cholesterol, LDL , found in red meats and fried foods. The good kind, HDL, pulls out the LDL that builds up on blood vessel walls and raises risk for a heart attack. Upping levels of HDL may therefore protect the heart from damage.
That's the theory, but studies looking at HDL levels and heart disease events haven't always shown that higher HDL levels lead to lower risk of disease. Scientists may finally know why. In a new study of nearly 300 people at high risk of heart disease, published in the journal Circulation , researchers found that just having high levels of HDL may not be enough to make a heart healthy. But the Mediterranean diet may help HDL to work more effectively.
The people in the yearlong study were randomly assigned to eat either a low-fat diet with little red meat and plenty of fruits and vegetables, or one of two versions of the Mediterranean diet : one enriched with olive oil and the other with nuts. After the year, the researchers compared the blood cholesterol levels of the participants to their starting levels. They found that only the people who ate the low-fat, non-Mediterranean diet lowered their total and LDL cholesterol levels, but that the people eating the two Mediterranean diets had better-working HDL.
The scientists, led by Montserrat Fito from the Hospital del Mar Medical Research Institute in Barcelona, knew this because they took other measurements of how well HDL was working. The group that ate the diet higher in olive oil showed the most improvement in HDL function; their HDL was better able to pluck out LDL from heart vessel walls and shunt them to the liver for removal, and it was better able to work as an antioxidant, protecting against the inflammation-related damage that can weaken blood vessels and make them more vulnerable to heart attack-triggering plaques. The HDL in this group was also better able to keep the blood vessels elastic and pliableimportant, since hardened arteries are more susceptible to damage.
Our hypothesis is that all the antioxidant compounds in olive oil bind to the HDL particle and preserve [it] from oxidative stress, says Fito. And that maintains the HDL in better quality.
The people eating the Mediterranean diet enriched with nuts also had some increase in HDL function, but the olive oil seemed to outwork even the nuts.
Its important to note that none of the three diets boosted the amounts of HDL considerably. While diets rich in fruits, vegetables and antioxidants, like the Mediterranean diet, can increase levels of HDL, experts say that other methods, including regular exercise, may be better. Scientists at drugs companies still havent found a drug that can increase HDL levels, either. Based on these new results, they may have to focus not just on increasing amounts of HDL, but also on making sure that HDL is working optimallyan effect olive oil seems to have naturally.
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Why Olive Oil Is So Good for the Heart - TIME
Posted: February 15, 2017 at 2:53 am
When you hear a science-y word linked with weight loss, your ears can't help but prick.
The latest one to get the attention of shredders is ketosis, a metabolic state achieved when you go on a low carbohydrate, high-fat diet that sees the body rely on "ketones" in the blood instead of glucose for energy.
Ketosis is caused when the body starts to break down body fat for energy, and is a sought-after state for people who want to blitz body fat.
Shifting your body into a ketogenic state is no easy feat given you have to subsist on a diet that's comprised of 20 percent protein, 75 percent fat and five percent carbohydrate.
Sports scientist Ben Greenfield says it takes the body anywhere from two weeks to six months to move into a ketogenic state.
"Once done, its done, and you have achieved fat-burning status that can stick with you for life," writes Greenfield, who says the ketogenic diet improved his triathlon performance, reduced hunger, improved mental clarity, reduced gas and bloating, and lowered inflammation markers.
Pretty convincing stuff however Melanie McGrice, a leading dietitian who runs online weight loss programs, told Coach that widespread studies into healthy weight people following ketogenic diets are lacking.
The keto lifestyle also puts you at risk of some pretty significant side effects.
"There is a risk of constipation because sometimes you are not getting as much fibre, and there is a risk of calcium deficiency as people often cut out dairy," she says.
"There is also concern about what low-carb diets will do to our gut microbiome [bacteria] because most prebiotic foods are really rich in carbohydrates."
Diabetes UK warns that actively trying to get your body into ketosis is potentially dangerous because high levels of ketones can make the blood acidic.
Greenfield also notes that a ketogenic diet can lead to high cholesterol, triglycerides and thyroid issues.
"Some people feel they have reduced energy although report having increased energy," McGrice says.
"It's very difficult to follow such a strict diet in today's culture especially anybody who wants to have a social life. Going out for dinner or to a wedding or somebody's house for dinner is very difficult."
Greenfield recommends using ketogenic supplements to help your body thrive in a ketogenic state. They contain ingredients such as beta-hydroxybutric acid (BHB), healthy fats and sometimes caffeine.
But McGrice is skeptical that they could work and says it's likely the caffeine or calories that are giving you energy.
"I havent seen any research that suggests that theres any benefits to providing the body with additional ketones, and physiologically, I cant imagine why it would as they are more of a byproduct," she says.
There is a place for ketosis McGrice says it's a good state to aim for if you are overweight with insulin resistance or Type 2 diabetes, but she wouldn't recommend it for a healthy weight person who just wants to drop a few kilos.
"I feel that there is not enough research [into whether] people of a healthy weight should be trying ketogenic diets," she says.
"I don't think there is any benefit for them but there can be some benefit sometimes for some people who are trying to lose weight.
But it would only work for somebody who finds it suits their lifestyle like they don't have a family to cook for and are not an emotional or binge eater."
McGrice adds that, if you are thinking about going keto, you should first speak to a dietitian experienced in this kind of diet. (Unsurprisingly, relying solely on blogs and Facebook pages for your ketosis knowledge isn't the best idea...)
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Ketosis: Why ketogenetic diets might not be your best weight-loss solution - 9Honey
Posted: February 15, 2017 at 2:53 am
Yo-yo dieting: What it is and how it can wreck your body Men's Fitness ... for weight loss is to take it steady," Higginson says. "Our work suggests that eating only slightly less than you should, all the time, and doing physical exercise is much more likely to help you reach a healthy weight than going on low-calorie ... |
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Yo-yo dieting: What it is and how it can wreck your body - Men's Fitness
Posted: February 15, 2017 at 2:53 am
Weve long known that what we eat affects the microbes in our bodies. Right now, hundreds of different species of bacteria are churning in our stomachs, working to protect us as well as survive within us. New research is showing that the bacterial microbiota of the gut could place chemical tags on our DNA and influence gene expression, potentially impacting our health and many aspects of our lives.
Researchers have found that these microbes send out metabolites that impact epigenetic marks on histones, or the proteins that DNA is wrapped around, in order to communicate with the host. Their actions can not only adjust gene expression in the stomach and colon, but also in tissues from numerous other parts of the body.
This is the first of what we hope is a long, fruitful set of studies to understand the connection between the microbiome in the gut and its influence on host health, said one of the senior authors of the study, John Denu, Professor of Biomolecular Chemistry at the University of Wisconsin, Madison. We wanted to look at whether the gut microbiota affect epigenetic programming in a variety of different tissues in the host.
In the study, the researchers assessed colon, liver, and fat tissue and compared mice that were germ-free versus those whose gut microbes were active. They discovered that the epigenome of numerous tissues in the mice was altered depending on the community of gut microbes.
Then they investigated whether two diets impacted the gut microbiota. Some mice were fed a normal, healthy chow diet and others were fed a Western-type diet that was low in fiber and carbohydrates and contained high amounts of simple sugars and fat. The results indicated that the diets did indeed alter the collection of bacteria in the gut in distinct ways.
Assistant Professor of Bacteriology and senior author from UW-Madison, Federico Rey, explained, When the host consumes a diet thats rich in complex plant polysaccharides (such as fiber), theres more food available for microbes in the gut, because unlike simple sugars, our human cells cannot use them.
The gut microbiota produces a myriad of metabolites that affect host physiology and susceptibility to disease; however, the underlying molecular events remain largely unknown, the researchers reported.
The mice on the Western diet produced less of particular metabolites short-chain fatty acids acetate, butyrate, and propionate than mice on the regular diet. Denu believes some of these metabolites, which are produced by microbial fermentation of fiber, might be crucial to causing these epigenetic effects spread throughout various mouse tissues.
SEE ALSO: 4 Ways Epigenetics May Explain Why Love is Not So Crazy
Lastly, they began to elucidate the link between metabolite production and epigenetic adjustments. Global histone acetylation and histone methylation levels differed depending on the mices diet. These epigenetic histone modifications can impact chromatin structure, thereby opening or closing access to certain genes during transcription. This can dictate whether some genes are expressed and some are not.
Our findings suggest a fairly profound effect on the host at the level of chromatin alteration, Denu explains. This mechanism affects host health through differential gene expression.
The team wanted to verify whether the metabolites produced were leading to the epigenetic change so they looked more closely at the germ-free mice. They put three short-chain fatty acids in their drinking water and found that the same epigenetic changes occurred as the mice on the regular, healthy diet. Specifically, they assessed the mices tissues and the epigenetic signatures mimicked each other.
Although further work needs to be carried out to translate these findings to humans, there is still significant evidence which speaks to the influence that gut microbiota has on our health and potentially our epigenome.
In those with diabetes and cardiovascular disease, Rey indicates that there is less bacteria that produces butyrate and that this short-chain fatty acid may reduce inflammation in the intestine.
However, the researchers dont suggest simply adding short-chain fatty acids to ones diet as a way to avoid eating healthy. Fruits and vegetables are a lot more than complex polysaccharides, Rey commented. They have many other components, including polyphenols, that are also metabolized in the gut and can potentially affect chromatin in the host in ways that we dont yet understand. Short-chain fatty acids are the tip of the iceberg, but theyre not the whole story.
Source: Krautkramer, et al. (2016). Diet-microbiota interactions mediate global epigenetic programming in multiple host tissues. Molecular Cell, 64(5):982-992.
Reference: Cell Press. Changes in the diet affect epigenetics via the microbiota. EurekAlert. 23 Nov 2016. Web.
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What You Eat Adjusts Your Gut Microbiota and Epigenetic Marks - WhatIsEpigenetics.com (blog)
