Search Weight Loss Topics:

Page 183«..1020..182183184185..190200..»

Happy Eating: The Ups and Downs of a Gluten-Free Diet in Japan – Nippon.com

Posted: December 19, 2021 at 1:52 am

Eating gluten-free foods as a healthy diet has yet to catch on in Japan to the degree it has in the United States and Europe. Improved food labeling in the last several years has increased recognition of allergies. However, living or traveling gluten-free in Japan is still comparatively difficult due to the pervasiveness of wheat in foods. A long-term resident who has lived without wheat products for nearly two decades offers advice on eating gluten-free while in Japan.

Moving to Japan in 2001 had unimagined consequences for my health. I had become severely lactose intolerant while attending grad school in the United States in the late 1990s, and my digestion only worsened after coming to Japan. No amount of careful dieting helped, nor did getting tested for allergies offer any clues for my condition.

I had become afraid to eat anything at all, since everything I ingested made me sick (I thought, like the sister in Laura Esquivels iconic novel Like Water for Chocolate, that I might actually die from gas). On top of all of the food problems, I suffered several miscarriages, which I later discovered can be caused by malnutrition stemming from gluten intolerance. Thanks to the newly blooming internet I also learned about elimination dieting, in which you cut out one possible allergen from your diet at a time over a period of months, and gave it a try.

The second thing I tried eliminating was wheat, and no further testing was necessary. My digestive woes disappeared, but most surprisingly the pain of my menstrual cycle, which previously left me in a fetal position for half a day every month, mellowed to a mild backache.

Unfortunately, at that time conditions like gluten intolerance and celiac disease were not widely recognized. My allergist referred me to a specialist who told me that there was no way I had a wheat allergy, as that was something only small children have, and they grow out of it. Even without a diagnosis, it was clear to me that I did not have a problem as long as I shunned wheat, so I trusted my gut. Subsequently, my skin rashes cleared up, my fingernails got thicker and stronger, my hair filled out, and I now have a healthy 16-year-old daughter.

Living wheat-free was much easier said than done, though, as food labeling in Japan was still relatively hit-and-miss. Thankfully, although gluten-free food has yet to really take off in Japan, identifying safe products is a lot easier now, in large part because of Japanese food labeling laws that have taken effect since 2015. Recognition of food allergies has also rapidly increased in recent years, and agricultural programs designed to promote rice consumption have increased the number and variety of products made with rice flour instead of wheat flour. Still, adhering to a medically necessary gluten-free diet in Japan is comparatively challenging, particularly if you are not fluent in both reading and speaking Japanese.

Water binding with the gliadin and glutenin proteins in wheat flour forms the large protein complex called gluten, found in wheat, barley, rye, and sometimes in oats. This complex protein binds to itself and forms a regular and continuous network of fine strands, allowing wheat flour to stick together to capture the air bubbles that create the foamy texture of bread. But thats not all; gluten is extremely elastic and can absorb about twice its own weight in water. These propertieswater absorption, stickiness, and plasticitymake it fantastically valuable in the food industry. In products like butter and ice cream it can be used to extend bulk and create a smooth texture. Wheat flour is commonly used in the freezing process of prepared foods containing rice to keep the grains from clumping up, as a binder and extender in processed meat products, and as a thickener or coloring agent in sauces. Gluten is even in some makeup and skin care products. Syrup sweeteners made from barley are a completely unlabeled way to encounter gluten in Japan.

Gluten intolerance, celiac disease, and wheat allergy are not the same thing, but the primary way to mitigate any of them is to completely eliminate wheat products from the diet.

A wheat allergy is a reaction to any of the four wheat proteins: albumin, globulin, gliadin, or glutenin. This is much easier to detect and diagnose than celiac or gluten intolerance, because the effects are almost always immediate: swelling or itchiness in the mouth and throat, nausea, vomiting, or even anaphylaxis, which can be fatal.

Celiac disease and gluten intolerance, meanwhile, are autoimmune disorders: a persons body has an adverse reaction to the large gluten protein complex. The reaction occurs mostly in the small intestine, and it can take a long time to damage the organ to the point where serious effects are felt immediately after ingesting gluten. For most sufferers, even the smallest bit of gluten will cause a reaction, but the outward manifestation can be delayed, sometimes by many hours, and the severity of the perceived problem may vary. Symptoms can range from bloating or gas to diarrhea, constipation, vomiting, headaches, skin rashes, and even hair loss or miscarriage. Many of the symptoms result from malnutrition caused by the damage to the intestine rather than from the immediate reaction to gluten in the gut, and people who have celiac disease or gluten intolerance may not even know they have it, but have general ailments and are unable to pinpoint the cause.

Lots of people may benefit from a gluten-free diet because they are actually mildly gluten intolerant and do not know it, or because a diet of this kind forces them to carefully monitor what they ingest. However, such a diet can be both much more expensive and less healthy than a regular diet if not properly understood. This is because many gluten-free products intended to mimic and replace traditional wheat products are primarily made of starchy ingredients like rice flour, tapioca starch, corn starch, and potato starch. The products may not be inherently unhealthy, but may have lower overall nutritional value and higher sugar levels than the wheat products they are intended to replace.

With a basic understanding of nutrition and food science, almost any traditional wheat-based dish can be made gluten free.

Perhaps counterintuitively, convenience stores are among the best places to get something safe to eat, as products are consistently and strictly labeled. However, you cannot rely on the allergen labeling because that information is only targeted at wheat allergy. It is best to learn enough Japanese to read the ingredient label itself, and beware of things like modified food starch (; kak denpun) and maltose (; bakugat). Other important words to look out for are cake flour (; hakurikiko) and even soy sauce ( or ; shyu)which, although made from soybeans, usually includes wheat in the production process. Even with standardized labeling rules, small food manufacturers are not always consistent with names of ingredients or with the allergy labels, so if you are not sure, do not eat it.

Large chain restaurants, known as famiresu (family restaurants) in Japan, now almost universally provide nutrition and allergy information online or even in the shop, making it relatively easy in larger towns and cities to find something to eat. Tokyo, Kyoto, and Osaka in particular have a handful of restaurants that either have completely gluten-free menus or serve gluten-free options, and these are pretty easy to find online. However, once you get away from population centers, finding a restaurant that will serve a gluten-free meal can be daunting. By far the safest bet is to find an authentic Indian restaurant. Real Indian curry is almost always gluten free, and typically comes with rice. Yakiniku (Korean barbecue) is pretty safe, but you have to be careful to specify that the meat you get is not marinated in anything, and watch out for the salad dressing. (In general plain salt and pepper is your safest bet.) If you bring your own gluten-free soy sauce and read the allergy listings carefully, you can usually eat some sushi, but beware that shops boasting lower prices sometimes use wheat vinegar instead of traditional rice vinegar.

One way you can really tell the quality of a restaurant or eating establishment is by the way they treat their food-challenged guests. A lot of places will give you a blank stare if you ask about gluten-free food, vegetarian options (vegans in Japan have a terrible time), or other allergy information. However, sometimes you will come across a real gem. Even if a local cafe just fixes you a bowl of rice and a simple egg omelet, it is great to be able to have a place to eat out with friends.

Home-made gluten-free pies.

Tragically, eating informally prepared food of any kind can lead to serious consequences. Many people still do not understand that soy sauce normally has wheat in it, or that rice balls prepared on the same cutting board where bread or tempura just rested could be contaminated. Even dashi broth made with consomm powder can have wheat in it, as can candy made from the traditional sweetener mizuame ( or). A person who has serious intolerance, allergy, or celiac should never accept home-prepared food in Japan unless the cook well understands the issues involved.

Unfortunately, medical resources like antibody testing and diet advice for gluten intolerance are still relatively hard to come by outside of Tokyo. However, online shopping has changed the game in the past 20 years. These days, ordering xanthan gum or even pure soba flour is simple and quick. Various online retailers offer all kinds of gluten-free noodles, breads, cakes, pies, and snacks, much of it delivered frozen and in small packages. Additionally, groups on social networking sites are extremely valuable for asking questions and finding products.

Larger supermarkets usually have a section with allergy-appropriate products, including things like gluten-free soy sauce and noodles. These tend to be fairly expensive, but helpful in a pinch. Few products in Japan, however, are marked gluten free unless they are specifically manufactured as such. In many cases you have to trust to sanitation laws and the careful packaging Japan is famous for. Cross contamination is not unheard of, but in general food processing standards in Japan are extremely high, so things like chocolate bars, mochi rice, and soba noodles made with jwari () 100% buckwheat flour can be trusted to be nothing more than what they say they are.

Living with celiac, gluten intolerance, or a wheat allergy in Japan can still be extremely disappointing, because you are never going to be able to eat tempura, ramen, gyza, takoyaki, or any of the thousand mouthwatering options available at local festivals and in izakaya However, with a bit of planning and a reasonable command of the Japanese language, you can eat well and even experience local cuisine to a certain extent. Nicer hotels will often bend over backward to provide a delicious and beautiful gluten-free meal, as will the more expensive restaurants and bars. If you do not speak any Japanese at all, print out and laminate one of the translated explanations you can find online, and just ask your host to read it. Use your cellphone to translate the labels of food products, and if all else fails get a simple salmon onigiri or a Soy Joy bar from the nearest convenience store.

Happy eating!

(Originally published in English. Banner photo: A selection of gluten-free ingredients. All photos Anne Kohtz.)

View original post here:
Happy Eating: The Ups and Downs of a Gluten-Free Diet in Japan - Nippon.com

Looking for ‘diet’ soda? It may be harder to find these days – WESH Orlando

Posted: December 19, 2021 at 1:52 am

As you make your way through the soda aisle, you may notice a lot less of the word "diet" than you used to.That's because some diet sodas are disappearing or at least, that packaging is gone. Instead, you'll find those beverages under their new branding: Zero sugar."Zero sugar" has replaced "diet" for many no-calorie soft drinks. Canada Dry and Schweppes ginger ales, 7Up, A&W and Sunkist, made by Keurig Dr Pepper, now label their diet drinks "zero sugar." (One exception is the namesake Dr Pepper brand, which will still come in "diet" packaging in addition to a different zero sugar version.)The reason for the overhaul: The word "diet" has fallen out of fashion especially for Millennials and Gen Z-ers."Younger people just don't like the word 'diet," said Greg Lyons, chief marketing officer at PepsiCo Beverages North America, during the Beverage Digest Future Smarts conference in December. Pepsi rebranded "Pepsi Max" as "Pepsi Zero Sugar" in 2016 and has been investing in its zero-sugar offerings over the past few years."No Gen Z wants to be on a diet these days," he said, adding that the company is "going to continue to innovate and support that business."But distaste for the word diet doesn't signal an aversion to no-calorie beverages. The diet soda segment, which includes diet and zero-calorie branded drinks, has ballooned since it first hit the mainstream in the 1960s. In 2020, the U.S. retail diet carbonated soft drink market hit $11.2 billion, according to Mintel, a market research company.The segment is still far smaller than the market for regular carbonated soft drinks, which was $28.2 billion in 2020, but it's growing much more quickly. Diet soda sales are up about 19.5% from 2018, compared to just 8.4% for regular soda in the same period, making it an attractive segment for soda makers seeking growth.Evolving attitudes toward dieting as a concept mean soda makers have to de-emphasize diet branding as they steam ahead with zero-sugar offerings even when, as in the case of those brands owned by Keurig Dr Pepper, they're selling the same exact drink.The tactic could help soda makers bring more consumers, especially younger ones, into the fold. The industry needs those customers if it wants to grow the soda market.The birth of diet colasDiet drinks first became popular in the 1960s.Diet Rite, a no-calorie drink from the soda maker Royal Crown Cola, was launched in 1958 "as an option for diabetics and other consumers who needed to limit their sugar intake," wrote Emily Contois, author of "Diners, Dudes, and Diets: How Gender and Power Collide in Food Media and Culture," in a 2020 piece for Jezebel."It was first stocked among medicines rather than soft drinks, but focus soon shifted to the growing number of weight loss dieters nationwide," she wrote. Diet Rite was a hit, prompting Coca-Cola to introduce Tab in 1963, and Pepsi to start selling Diet Pepsi a year later.The segment gained steam in the following years. Looking to expand beyond Tab, Coca-Cola launched Diet Coke in 1982.At the time, Coca-Cola was facing many of the same challenges it is fighting today: It needed to reinvigorate the Coca-Cola brand, and thought adding a Coke-branded diet option could help. A company blog post detailing the launch of Diet Coke noted that "colas accounted for 60% of all soft drink sales in the U.S. back then, but diets were growing three times faster than the rest of the category. Diet Coke was seen as the right product for the right time."The company grappled with what to name the product. It considered using the moniker "sugar free" instead of diet, but "many saw it as a slur on Coca-Cola's main ingredient," according to the post. Ultimately, the company went with "diet" because it "was the most straightforward articulation of the promise of the brand."But a few decades later, Coca-Cola returned to the idea of a sugar-free-branded product. This time, it wanted to attract the demographics that seemed to be avoiding the company's diet beverages: younger consumers and men.Zero hits the sceneIn 2005, Coca-Cola introduced Coke Zero in the United States.Other companies also wanted a more neutral way to advertise no-sugar products.Eliminating the word "diet" creates a "gender-free way to talk about the same topic," said Jim Watson, senior beverage analyst at Rabobank, who told CNN Business that "diet definitely got taken over as something for women."But the arrival of zero-sugar drinks wasn't just about gender: It marked a turning point for the overall popularity of diet drinks. Alex Beckett, global food and drink analyst at Mintel, said the word diet "started falling out of fashion ... with the rise of zero."Billing a drink as free of calories and sugar is also about addressing changing ideas about health, and highlighting the absence of sugar from the drink as a positive attribute in itself."While the diet designation may be associated with strict regimes or deprivation, the 'zero' designation has fewer negative connotations, corresponding with simply a cleaner profile," according to a Mintel report from April.For Keurig, the shift seems to be working. Recent zero sugar launches alone were responsible for one percentage point of market-share gains for the company, according to Herbert Hopkins, president of cold beverages at Keurig Dr Pepper, who detailed the company's finances during the company's investor day in October.Coca-Cola has also seen success with its Zero offering, which was rebranded to Coca-Cola Zero Sugar in 2017 and got another update this year. "Coca-Cola Zero Sugar's new recipe has rolled out in more than 50 countries and has had accelerated growth in the last three months," said Coke CEO James Quincey during an analyst call in October.The new recipe arrived on shelves in the U.S. this summer, and since then "we have seen that 23% of current Coke Zero Sugar consumers are new," said Alex Ebanks, a spokesperson for the company, adding that Coca-Cola will continue to invest in the product next year and beyond.Competition heats up While big brands sharpen their focus on their zero-sugar offerings, they face competition from other categories and upstarts with novel ideas.One major competitor, according to Mintel's Beckett, is sparkling water."Many people are shifting over ... from carbonated soft drinks to sparkling waters," he said, because those drinks often have no sweeteners, no calories, and "have a more of a health healthy image."PepsiCo and Coca-Cola have offered their own sparkling waters to get in on the trend. Coca-Cola owns Topo Chico and has a line of caffeinated sparkling water called Aha, while PepsiCo sells Bubly.Beyond sparkling waters, competitors are entering the space with fresh spins on sodas. For example: Sodas that promote gut health.Olipop, a startup that says it makes "a new kind of soda," sells throwback flavors like classic root beer, vintage cola and others. The sodas, which range from about 35-50 calories each, are made with a mix of ingredients like Jerusalem artichoke and Cassava root that the company says support digestive health. Poppi, which also sells traditional soda flavors in addition to fruit flavors, makes a similar claim, emblazoning a "for a healthy gut" label on the front of its brightly colored cans."Consumers are voting with our wallets, and sugar is something that people definitely want less of in our lives," said Danny Stepper, CEO of LA Libations, a beverage company incubator. "That opens the door for a lot of opportunities and categories," he said. "Consumers want new things, so that's opening the door to new ideas."

As you make your way through the soda aisle, you may notice a lot less of the word "diet" than you used to.

That's because some diet sodas are disappearing or at least, that packaging is gone. Instead, you'll find those beverages under their new branding: Zero sugar.

"Zero sugar" has replaced "diet" for many no-calorie soft drinks. Canada Dry and Schweppes ginger ales, 7Up, A&W and Sunkist, made by Keurig Dr Pepper, now label their diet drinks "zero sugar." (One exception is the namesake Dr Pepper brand, which will still come in "diet" packaging in addition to a different zero sugar version.)

The reason for the overhaul: The word "diet" has fallen out of fashion especially for Millennials and Gen Z-ers.

"Younger people just don't like the word 'diet," said Greg Lyons, chief marketing officer at PepsiCo Beverages North America, during the Beverage Digest Future Smarts conference in December. Pepsi rebranded "Pepsi Max" as "Pepsi Zero Sugar" in 2016 and has been investing in its zero-sugar offerings over the past few years.

"No Gen Z wants to be on a diet these days," he said, adding that the company is "going to continue to innovate and support that business."

But distaste for the word diet doesn't signal an aversion to no-calorie beverages. The diet soda segment, which includes diet and zero-calorie branded drinks, has ballooned since it first hit the mainstream in the 1960s. In 2020, the U.S. retail diet carbonated soft drink market hit $11.2 billion, according to Mintel, a market research company.

The segment is still far smaller than the market for regular carbonated soft drinks, which was $28.2 billion in 2020, but it's growing much more quickly. Diet soda sales are up about 19.5% from 2018, compared to just 8.4% for regular soda in the same period, making it an attractive segment for soda makers seeking growth.

Evolving attitudes toward dieting as a concept mean soda makers have to de-emphasize diet branding as they steam ahead with zero-sugar offerings even when, as in the case of those brands owned by Keurig Dr Pepper, they're selling the same exact drink.

The tactic could help soda makers bring more consumers, especially younger ones, into the fold. The industry needs those customers if it wants to grow the soda market.

Diet drinks first became popular in the 1960s.

Diet Rite, a no-calorie drink from the soda maker Royal Crown Cola, was launched in 1958 "as an option for diabetics and other consumers who needed to limit their sugar intake," wrote Emily Contois, author of "Diners, Dudes, and Diets: How Gender and Power Collide in Food Media and Culture," in a 2020 piece for Jezebel.

"It was first stocked among medicines rather than soft drinks, but focus soon shifted to the growing number of weight loss dieters nationwide," she wrote. Diet Rite was a hit, prompting Coca-Cola to introduce Tab in 1963, and Pepsi to start selling Diet Pepsi a year later.

The segment gained steam in the following years. Looking to expand beyond Tab, Coca-Cola launched Diet Coke in 1982.

At the time, Coca-Cola was facing many of the same challenges it is fighting today: It needed to reinvigorate the Coca-Cola brand, and thought adding a Coke-branded diet option could help.

A company blog post detailing the launch of Diet Coke noted that "colas accounted for 60% of all soft drink sales in the U.S. back then, but diets were growing three times faster than the rest of the category. Diet Coke was seen as the right product for the right time."

The company grappled with what to name the product. It considered using the moniker "sugar free" instead of diet, but "many saw it as a slur on Coca-Cola's main ingredient," according to the post. Ultimately, the company went with "diet" because it "was the most straightforward articulation of the promise of the brand."

But a few decades later, Coca-Cola returned to the idea of a sugar-free-branded product. This time, it wanted to attract the demographics that seemed to be avoiding the company's diet beverages: younger consumers and men.

In 2005, Coca-Cola introduced Coke Zero in the United States.

Other companies also wanted a more neutral way to advertise no-sugar products.

Eliminating the word "diet" creates a "gender-free way to talk about the same topic," said Jim Watson, senior beverage analyst at Rabobank, who told CNN Business that "diet definitely got taken over as something for women."

But the arrival of zero-sugar drinks wasn't just about gender: It marked a turning point for the overall popularity of diet drinks. Alex Beckett, global food and drink analyst at Mintel, said the word diet "started falling out of fashion ... with the rise of zero."

Billing a drink as free of calories and sugar is also about addressing changing ideas about health, and highlighting the absence of sugar from the drink as a positive attribute in itself.

"While the diet designation may be associated with strict regimes or deprivation, the 'zero' designation has fewer negative connotations, corresponding with simply a cleaner profile," according to a Mintel report from April.

For Keurig, the shift seems to be working. Recent zero sugar launches alone were responsible for one percentage point of market-share gains for the company, according to Herbert Hopkins, president of cold beverages at Keurig Dr Pepper, who detailed the company's finances during the company's investor day in October.

Coca-Cola has also seen success with its Zero offering, which was rebranded to Coca-Cola Zero Sugar in 2017 and got another update this year. "Coca-Cola Zero Sugar's new recipe has rolled out in more than 50 countries and has had accelerated growth in the last three months," said Coke CEO James Quincey during an analyst call in October.

The new recipe arrived on shelves in the U.S. this summer, and since then "we have seen that 23% of current Coke Zero Sugar consumers are new," said Alex Ebanks, a spokesperson for the company, adding that Coca-Cola will continue to invest in the product next year and beyond.

While big brands sharpen their focus on their zero-sugar offerings, they face competition from other categories and upstarts with novel ideas.

One major competitor, according to Mintel's Beckett, is sparkling water.

"Many people are shifting over ... from carbonated soft drinks to sparkling waters," he said, because those drinks often have no sweeteners, no calories, and "have a more of a health healthy image."

PepsiCo and Coca-Cola have offered their own sparkling waters to get in on the trend. Coca-Cola owns Topo Chico and has a line of caffeinated sparkling water called Aha, while PepsiCo sells Bubly.

Beyond sparkling waters, competitors are entering the space with fresh spins on sodas. For example: Sodas that promote gut health.

Olipop, a startup that says it makes "a new kind of soda," sells throwback flavors like classic root beer, vintage cola and others. The sodas, which range from about 35-50 calories each, are made with a mix of ingredients like Jerusalem artichoke and Cassava root that the company says support digestive health. Poppi, which also sells traditional soda flavors in addition to fruit flavors, makes a similar claim, emblazoning a "for a healthy gut" label on the front of its brightly colored cans.

"Consumers are voting with our wallets, and sugar is something that people definitely want less of in our lives," said Danny Stepper, CEO of LA Libations, a beverage company incubator. "That opens the door for a lot of opportunities and categories," he said. "Consumers want new things, so that's opening the door to new ideas."

View post:
Looking for 'diet' soda? It may be harder to find these days - WESH Orlando

Risks of testosterone replacement therapy in men

Posted: December 19, 2021 at 1:52 am

Indian J Urol. 2014 Jan-Mar; 30(1): 27.

Department of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, Starr 900, New York, NY, USA

Department of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, Starr 900, New York, NY, USA

Department of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, Starr 900, New York, NY, USA

Department of Urology, New York Presbyterian Hospital, Weill Cornell Medical College, Starr 900, New York, NY, USA

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Testosterone replacement therapy (TRT) is a widely used treatment for men with symptomatic hypogonadism. The benefits seen with TRT, such as increased libido and energy level, beneficial effects on bone density, strength and muscle as well as cardioprotective effects, have been well-documented. TRT is contraindicated in men with untreated prostate and breast cancer. Men on TRT should be monitored for side-effects such as polycythemia, peripheral edema, cardiac and hepatic dysfunction.

Keywords: Hypogonadism, side-effects, testosterone replacement therapy

Testosterone has many beneficial effects, including increasing bone strength and density, inducing hematopoiesis, driving sexual function and libido, providing a cardioprotective effect and increasing muscle strength.[1] Testosterone levels are known to decline as men age. The Baltimore Longitudinal Study of Aging reported the incidence of hypogonadism as 20% in men over 60 years of age, 30% in men over 70 years and 50% in men over 80 years of age.[2]

As men age, a decline in testicular production of testosterone are seen, as well as an increase in sex hormone binding globulin, both of which act to decrease bioavailable testosterone.[3] With this gradual decline, the beneficial effects of testosterone could be diminished and negatively affect physical and emotional well-being. Testosterone replacement therapy (TRT) is a reasonable treatment option often discussed for men with low testosterone levels and symptoms of hypogonadism. When replaced, many of the positive effects of testosterone are regained.[4] These positive results have led to a drastic increase in the use of testosterone replacement for men with symptomatic hypogonadism, though long-term data is lacking on the safety.

While the beneficial effects of testosterone are rarely disputed and widely publicized, there is a paucity of the literature on the risks of testosterone use. Any man who has a comorbidity that precludes TRT should be informed of all risks. Factors such as exacerbation of prostate cancer, male breast cancer, worsening benign prostatic hyperplasia (BPH), polycythemia and an increased risk of obstructive sleep apnea (OSA) should be considered when administering TRT to a patient. The goal of this review is to highlight the risks and summarize the current literature on safety of TRT.

One of the major risk factors associated with the administration of testosterone supplementation is its effect on the prostate. We know the prostate to be an androgen-dependent gland and conversely, anti-androgen agents can decrease prostate volume in patients with BPH. As the population continues to age, both the incidence of BPH and late-onset male hypogonadism will continue to rise and practitioners will need to be comfortable with counseling men on the effect of TRT on the prostate.[5]

In a landmark randomized, double-blind, placebo-controlled trial of 44 hypogonadal men, Marks et al. showed that TRT for 6 months improves serum androgen levels, but had little effect on prostate tissue androgen levels, tissue biomarkers and/or gene expression.[6] Testosterone supplementation has been shown to increase prostate size by 12%,[7] but lower urinary tract symptoms (LUTS) and urinary retention do not worsen in men on testosterone therapy.[8,9] Similarly, the presence of hypogonadism in 312 men with reportable LUTS was not predictive of worsening International Prostate Symptom Scores (IPSS) or maximal urinary flow rates.[10]

In fact, some series report an improvement in LUTS after 1 year of TRT.[11,12] In the most recent, randomized controlled trial, 52 men were randomly assigned to receive TRT. At 1 year, the 23 men randomized to 250 mg of testosterone enanthate every 4 weeks reported significant improvements in IPSS and maximal urinary flow rates compared with baseline and controls.[12] At no point in this trial did any patient require additional medication or suffer urinary retention.

While older men on testosterone therapy do have an increase in overall prostate size, this increase in size does not differ from the increase in prostatic hypertrophy seen in elderly men not on testosterone therapy.[13] Taken together, TRT does not appear to grossly worsen LUTS and is not contraindicated in men diagnosed with BPH.

It has been over 60 years since Hodges and Huggins described a relationship between serum testosterone levels and prostate cancer progression.[14] Later in 1982, Fowler and Whitmore reported that exogenous testosterone given to patients with metastatic prostate cancer had worse outcomes.[15] Today androgen deprivation therapy remains a cornerstone of treatment for men with advanced prostate cancer, so it is no surprise that TRT is contraindicated in men with diagnosed prostate cancer, as well as high-risk patients, which includes men with first-degree relatives with prostate cancer and African-Americans who have a prostate-specific antigen (PSA) >3 ng/mL.[4,16]

Recently, there has been a paradigm shift whereby TRT usage has increased despite this potential risk. Many longitudinal studies investigating the relationship of endogenous testosterone levels and subsequent risk of prostate cancer failed to find any association.[17] As such, prostate cancer incidence in men on testosterone therapy is similar to men not on testosterone therapy.[18,19] Similarly, in a 3-year prospective trial, the incidence of prostate cancer was similar among men receiving TRT and controls.[20] In a large meta-analysis of 18 prospective studies that included over 3500 men, there was no association between serum androgen levels and the risk of prostate cancer development.[21] Morgentaler et al. proposed a saturation theory where prostate growth becomes insensitive to changes at normal androgen levels due to saturation of the androgen-receptor; however, there is exponential growth at castrate levels.[22] This theory may explain why testosterone does not directly cause prostate cancer,[23] but it has been shown to accelerate the development of prostate cancer.[24,25]

For premalignancy, prostatic intraepithelial neoplasia (PIN) appears to be a risk factor for developing prostate cancer, however this association has been mostly demonstrated for high-grade disease.[26,27] There is a lack of long-term data on the use of TRT in men with PIN. In one study, 12 months after TRT, only one patient out of 20 men with previous PIN developed overt prostate cancer.[28]

For men who have previously undergone definitive treatment for prostate cancer, the usage of TRT is becoming more accepted. TRT does not appear to increase cancer recurrence in hypogonadal men following radical prostatectomy.[29] In the most recent study by Pastuszak et al., the authors retrospectively reviewed a cohort of 103 men who underwent prior radical prostatectomy and were treated with TRT. Despite a significant increase in PSA in men receiving TRT, there were twice as many cancer recurrences in the control group after 36 months of follow-up.[30]

For men with untreated prostate cancer on active surveillance, TRT remains controversial. However, several studies have shown that TRT is not associated with progression of prostate cancer as evidenced by either PSA progression or gleason grade upstaging on repeat biopsy.[31,32] In the most recent study by Morgentaler et al., 13 men with symptomatic hypogonadism and untreated prostate cancer received TRT for a median of 2.5 years and no local prostate cancer progression or distant disease was observed.[33]

While there have been reports of metastatic prostate cancer in older men who are on testosterone therapy,[20] these are mostly anecdotal. Because of this potential risk, practitioners are often reluctant to administer testosterone in patients they believe may be at high risk for prostate cancer or whom they suspect may have the low-grade disease. Men on TRT should have frequent PSA monitoring; any major change in PSA (>1 ng/mL) within the first 3-6 months may reflect the presence of a pre-existing cancer and warrants cessation of therapy.[34] Current guidelines on the frequency of PSA monitoring and role of pre-treatment transrectal ultrasound guided prostate biopsy are lacking.[35] Taken together, there has been consistent rejection that TRT causes development of prostate cancer in men, however administration of TRT for hypogonadal men previously treated for high-risk prostate cancer should be taken with caution.

While there is no known physiologic link of testosterone directly to the development of breast cancer, it has been suggested that high levels of testosterone may lead to increased aromatization to an active derivative of estrogen, which ultimately may stimulate breast tissue receptors and increase the risk of male breast cancer.[36]

The role of testosterone in breast cancer development is yet to be fully understood.[37] Currently, several case reports exist[38] and one retrospective review sites an incidence 11% in 45 men on long term TRT over 10 years.[39] Future prospective studies with longer follow-up will determine if such association between TRT and male breast cancer truly exists.

Testosterone leads to an increase in hemoglobin by as much as 5-7%[1,25] through its effect on the production of erythropoietin, which can dramatically improve symptoms of anemia in men.[40,41]

Studies looking at the occurrence of polycythemia as a negative side-effect in men on testosterone therapy are rare. Despite this, polycythemia is an accepted side-effect of TRT. While testosterone exerts a positive effect in men with baseline anemia, it can lead to polycythemia in over 20% of men treated on TRT.[42] Polycythemia may lead to an increased incidence of vascular events, including stroke, myocardial infarction and deep vein thrombosis with possible pulmonary embolus.[42] While these complications are all possible with polycythemia, their theoretical occurrence has not been demonstrated to occur in men on TRT.[43]

Because of this risk of polycythemia, men undergoing TRT should not only have their complete blood count (CBC) monitored during their therapy, but should also have a baseline CBC drawn before testosterone therapy is initiated. While on testosterone therapy, if the hematocrit (HCT) rises greater than 54%, testosterone therapy should be held until the HCT normalizes. If it is restarted after normalization, it should be performed so at a lower dose with continued careful monitoring.[16]

OSA is a risk associated with TRT in men, but its etiology is not particularly well understood. While some studies suggested that there is no association between OSA and TRT,[44] others have demonstrated that that OSA occurs in men undergoing TRT and when supplementation is stopped, the OSA resolves.[45]

While no clear link has been established, men on TRT should be counseled on the risk of potential OSA when therapy is started. They should be monitored for increased symptoms, such as snoring while sleeping or fatigue. If patients starting TRT already carry a diagnosis of OSA, physicians should counsel these patients that TRT may worsen their symptoms. While, OSA remains to be a relative contraindication to initiation of TRT, more research needs to be completed on this association in order to gain a better understanding of its etiology if there is one at all.

The systemic effects of TRT may be exacerbated in men with limited cardiovascular reserve. Previous dogma held that androgens could have atherogenic potential. In a randomized, placebo-controlled trial, Basaria et al. reported an increased risk of cardiovascular events in men randomized to TRT; however, this small cohort had a high prevalence of chronic disease.[46] Today, current literature suggests that TRT has a neutral to beneficial effect on reported cardiovascular events.[47,48] Because some men may have a limited cardiovascular capacity, clinicians prescribing TRT must be cautious with respect to its ability to cause edema.[49] Until date, no longitudinal studies examine the impact of TRT on the cardiovascular system, however some studies suggest that TRT may serve as an adjunct rehabilitative therapy in patients with congestive heart failure (CHF).[50,51,52]

While topical testosterone delivery systems avoid first-pass hepatic metabolism, there remains concern regarding TRT in patients with chronic liver disease. The majority of reports of liver toxicity and jaundice are limited to orally-administered alkylated forms of testosterone.[53] However, a small prospective study representing a cohort of cirrhotic patients demonstrated topical gels to be safe and efficacious.[54] It has also been shown that TRT may improve hepatic function in patients with end-stage liver disease.[55] Because of these mixed results, clinicians should be aware of the possible risks associated with TRT in men with hepatic dysfunction and counsel these men accordingly.

Because TRT is known to cause water retention, caution with testosterone use in patients with chronic renal insufficiency is often advised. In patients with end-stage renal disease (ESRD) on dialysis, fluid shifts are less of a concern in patients on TRT since the fluid retention can be handled with dialysis. While polycythemia may be an adverse side-effect, this is a potential benefit in patients with chronic renal failure and anemia.[56] Furthermore, the half-life of testosterone elimination after withdrawal appears similar between patients with and without ESRD.[56] Few studies have assessed the effects of TRT in patients with chronic kidney disease; however, small studies have suggested that TRT has anabolic effects among ESRD patients, even in the absence of hypogonadism. Aside from frequent monitoring of congestive symptoms and peripheral edema in this select population, TRT appears to be safe for patients with chronic kidney disease without dose adjustment.[57]

When testosterone reaches supra-therapeutic levels, aggressive behavior and increased rates of suicide among adolescent users have been reported;[58] however, no study has documented a negative impact on cognition in men patients receiving TRT. In fact, studies have shown that testosterone replacement to eugonadal levels may improve or stabilize cognitive function.[59,60,61] Lower levels of testosterone have a negative impact on spatial and verbal abilities, as well as cognitive function; therefore, it is no surprise that normalizing testosterone levels results in cognitive improvements.[62,63]

With exogenous testosterone supplementation, the pulsatile release of gonadotropin-releasing hormone is blunted and the release of follicle-stimulating hormone and luteinizing hormone are depressed. As such, a decrease in spermatogenesis is seen.[64] While this effect may not be of importance to many men who have completed their families, physicians prescribing TRT need to be aware.

When serum levels of testosterone are increased, a concurrent increase in the secretion of sebum occurs, which can lead to acne. Despite this known association, this effect is typically minimal.[65] Case reports regarding testosterone supplementation leading to changes in hair patterns have been documented; however no randomized, placebo-controlled trials exist. Various topical and intramuscular injectable forms of testosterone are associated with a variety of skin reactions, mainly erythema and pruritus in up to 60% of users.[20]

TRT is associated with external, physical changes in the men. Exogenous testosterone is known to cause an imbalance in the hypothalamic-pituitary axis. As such, testosterone can be converted to estrogen by aromatization. Excess estrogens may lead to gynecomastia and/or breast pain, both of which may be seen in 10-25% of men on TRT.[66] The ratio of estradiol to androgens is the key factor in the development of gynecomastia rather than absolute increases in androgens themselves.[66] Clinicians must be aware of non-iatrogenic causes of gynecomastia and therefore the appropriate work-up should be sought out to rule out other pathology, especially if there is any breast tenderness or unilateral gynecomastia. Only a few case-reports describe a relationship between male breast cancer and TRT.[38,39]

In addition, excess estrogens may cause an increase in visceral obesity. With vigilant monitoring of serum estrogen levels, TRT has been shown to promote weight loss.[67] Well-known to many prescribers of TRT is a risk of water retention and/or edema. The etiology of this association remains unclear to date.[68] The degree of retention is generally mild. As mentioned above, men on TRT with a history of CHF should follow closely[69].

TRT has numerous benefits that can great enhance a patient's quality-of-life. Before prescribing TRT, one must be conscientious of its adverse effects. Data on the safety of TRT specific to our aging population is not currently available; however TRT has been linked to prostate cancer, BPH, polycythemia and OSA. A full assessment of the morbidity of TRT would require a large-scale, randomized, controlled trial. To date, physicians remain in a quandary about the best approach to care for men with symptoms of hypogonadism. TRT, when given to appropriately selected patients with vigilant monitoring as outlined in this review and in , can bring improvements in quality-of-life, energy level, libido, muscle mass, cognition and bone density.

Potential risks of TRT and associated monitoring strategies

Source of Support: Nil

Conflict of Interest: None declared.

Read this article:
Risks of testosterone replacement therapy in men

CrazyBulk Reviews 2022: How Good Is the Legal Steroids Brand? – Cleveland Scene

Posted: December 19, 2021 at 1:52 am

We are pretty sure that you've heard about legal steroids and read unbelievable Crazy bulk reviews. These amazing health supplements have transformed the way natural bodybuilders look and feel.

In other words, they have bridged the massive void that existed between anabolic steroids and run of the mill health supplements like protein powder.

In case you were unaware, CrazyBulk is the company that pioneered Legal Steroids.

The brand has managed to single handedly spearhead the safe and clean bodybuilding movement by making it possible for natty bodybuilders to stand toe to toe with chemically enhanced bodybuilders.

But we've got to tell you this. We don't blame you at all if you were skeptical about Crazy bulk.

Some of the transformations made possible with their steroids are bound to draw suspicion. Moreover, there are no clear Crazy bulk reviews on the internet that explain how these supplements work and whether or not, they are safe for long term use.

That's why we have created this Crazy Bulk review. Today, we will analyze Crazy bulk from head to toe for you and try to shine more light on steroids than what other Crazybulk reviews tell you.

Click Here to Visit Crazybulk Official Website

Crazybulk USA Supplements is a brand of health supplements that is dedicated to men who want nothing short of enhanced bodybuilding performance. In other words, the company specializes in steroids.

As far as we know, they were the ones who came up with the term steroids. Until then, legal steroids were a catchall phrase used to describe prohormones, peptides, and other chemicals that were in essence, anabolic steroids. But were modified to an extent that they could fly under the radar without being detected.

But if you are a natty bodybuilder, the only difference that these bought to the table, was that they were legal. Other than that, it was as good as using steroids.

They had all the side effects. Sometimes, even worse than using AAS because users expected these to be a free ride and then would be caught unaware with severe liver stress and hair loss.

Crazybulk USA Supplements came up with their own brand of steroids that were not only legal but were completely natural and safe. These were legitimate performance enhancement compounds with no male hormones derivatives.

They mimic the effect of the anabolic agent without causing any of the side effects associated with them. For example, Trenbolone is the most powerful steroid there is. It's an extremely potent androgen receptor agonist that can boost nitrogen retention, protein synthesis, and red blood cells count.

But Trenbolone is also the most toxic steroid of them all. It can cause severe cardiovascular issues, is a bronchoconstrictor, & has long term mental health issues too. In comparison, Crazybulk offers Trenorol, a legal alternative to Trenbolone that mimics the result of Trenbolone without any of the side effects.

Click here for Best Price on Crazybulk Official Website

Crazy Bulk Supplements is owned by Wolfson Berg, one of the world's leading producers of health supplements. The company is based in Los Angeles, California, and has been around since 2009.

Wolfson Berg has a flawless reputation in the industry in over 11-years of business. That has been made possible due to few things.

Click here for Best Price on Crazybulk Official Website

Crazybulk USA Supplements work by achieving anabolic synergy. This means that their products are more than the sum of their parts because they work in conjunction with each other to elicit enhanced metabolic responses.

Each one of their bodybuilding supplements is designed to produce results like their anabolic counterparts and hence, produce a different result when combined together.

For example, D-BAL is a legal alternative to Dianabol which helps in increasing strength and massive muscle gains. But if you combine it along with Anadrole (a legal steroid alternative to Anadrol) then the synergy divines exponentially, giving you greater results than just adding up the two separate products together.

Some of their steroids work by increasing the levels of endogenous testosterone. But others increase the levels of endogenous HGH and IGF-1, both of which are potent muscle building hormones.

Some of their bodybuilding supplements are designed to increase metabolism (the body's internal temperature), so they help you build muscle and burn fat, at the same time.

Others are more geared towards preventing fat gain or water retention while parting dietary nutrients making them more adept for muscle growth.

Crazy Bulk became a rage in the health and fitness industry after they launched D-Bal, the legal alternative to Dianabol.

Almost overnight, natural athletes and sportsmen realized that they had a legitimate dietary supplement that could produce dramatic gains as fast as anabolic steroids do, that too without the fear of side effects or being busted for doping.

D-Bal sold out weeks in advance and the demand was so strong for bulking steroids that Crazy bulk decided to launch several more anabolic compound clones designed especially for bulking.

If you are looking to bulk with Crazy bulk steroids, these are your best options.

D-Bal is the first bulking legal steroid to have gained so much traction. It is a dietary supplement that has been designed to mimic the effects of Dianabol, or Methandrostenolone, the most (in)famous bulking, oral steroid of all times.

Dianabol was a favorite amongst golden era bodybuilders because of its uncanny ability to increase lean muscle mass in the shortest time possible.

In fact, it was so popular that it is estimated to have been taken by over half a million Americans during this era.

However, there were two major problems with Dianabol -

1) It caused extreme side effects

2) It was difficult to control the dosages and it nearly always led to excess dosages.

D-Bal solves both these problems for you, making it the number one bulking steroid alternative in Crazybulk USA's stable of steroids. It stimulates protein synthesisto produce increased muscle mass.

It not only produces huge muscle gains but also has serious cutting properties because it increases nitrogen retention, which in turn helps build muscle mass while burning fat.

When you take D-Bal, you can get up to 10 pounds of muscle growth in a month and the best part is that it only costs $69.99 for a month's supply.

Click here for D-Bal Best Price at Official Website

2- Testo-Max - The Legal Testosterone Clone

If there is any legal steroid after D-Bal that is equally popular, then it has to be Testo-Max. Millions of men around the world are testosterone deficient. While Testosterone replacement therapy is a solution, not everyone is ready for it.

Many people choose to skip TRT because they fear being enslaved by a lifetime of injections. Besides, TRT is a lengthy and expensive process. For weeks and months, you will be struggling to dial down your hormonal baseline.

Testo-Max offers you the same end results with none of the hassles. It's an oral capsule that boosts testosterone levels by up to 72% thanks to ingredients like d aspartic acid. When your serum and free testosterone levels increase, you will get all the benefits associated with it.

Your body builds muscle mass much quicker. You have increased blood flow to the muscle tissue, which enables faster repair. Your sex life skyrockets as your libido and energy levels increase.

Testo-Max is the ultimate mass builder that will also bring about a marked improvement in your quality of life.

Click here for Testo-Max Best Price at Official Website

Decaduro is the bulking steroid alternative that you can take over a longer period of time without worrying about the hassle of managing your hormonal levels.

While its effects are not as pronounced as D-Bal or Testo-Max, Decaduro will help you gain muscle consistently. It is the legal alternative to Deca-Durabolin, one of the oldest and most effective bulking steroids ever made.

Think slow but a steady way to gain muscle. Also, it's not watery, mind you. You get thick slabs of muscle mass with very little, to no water retention or fat gain.

Decaduro is also advantageous for sportsmen because it increases collagen synthesis, thereby promoting recovery and reducing pain caused due to joint health issues. In fact, we know of many sportsmen who use Deca duro year round purely for this.

Deca provides an essential balance to D-Bal's extreme nature. It is for this reason that when you take all three products together in a cycle, you can expect much faster results than when you use them separately.

Click here for Decaduro Best Price at Official Website

Anadrole is the legal alternative to Anadrol, the bulking steroid that charged a generation of men into a new era of epic gains. Anadrol is often considered the twin to Dianabol.

The difference between the two is the kind of muscle tissue that each one produces. Dianabol produces a very wet mass while Anadrol produces a slow and steady increase in both strength and muscle mass.

Anadrole is the legal steroid that produces a similar 'kind' of muscle tissue as Anadrol does. It will help you get bigger and stronger by increasingred blood cells countand thus improving nutrient delivery to your muscles. It offers all the benefits of an intense bulking cycle without any risks.

For instance, Anadrol is notorious for causing debilitating muscle cramps. So much so, that you have to often supplement with Taurine to just make it bearable. It can also increase red blood cells to an extent that it thickens your blood. But Anadrole does not cause these problems. You get the pumps for sure. But without the pain. Your red blood cells increase, but only enough to support anabolism.

Click here for Anadrole Best Price at Official Website

When bulking steroids became a rage, it was obvious that users started to demand a solution for the fat loss phase of their workout.

Crazy bulk responded by launching two products that help you lose weight, - Clenbutrol and Winsol, both legal steroid alternatives to Clenbuterol and Winstrol respectively. Both are extremely effective for any fitness goal that demands that you lose weight.

But cutting is not always about just losing fat. Sometimes, it is also about preserving muscle and even gaining dry muscle tissue. That's why Crazy bulk announced the launch of two more amazing cutting agents, completing a well-rounded portfolio of steroids.

Here's a look at the best cutting steroids from the brand.

Clenbuterol, the sympathomimetic nervous system stimulant is the most popular fat burner used by pros. But even pros generally limit the usage to a few weeks because of howtoxic Clenbuterol is.

That's why Crazy bulk came up with Clenbutrol. Don't miss the missing 'E'. Clenbutrol is the legal alternative to synthetic Clenbuterol. It is an all-natural, potent cutting steroid that mimics the lipolysis effect of clen, without the stimulation and hence, the side effects.

Clenbutrol is a remarkable legal steroid. Its obvious use is in a cutting phase. But most people are unaware of how amazing this legal steroid is while trying to retain lean muscle. For this reason, your cuts become more effective.

You don't end up looking skinny and unhealthy on Clen. Also, it is a terrific legal steroid to stack with bulking compounds. You peel away stubborn body fat and retain the muscle mass.

Click here for Clenbutrol Best Price at Official Website

Anvarol is not exactly a cutting steroid. It is powerful enough to promote muscle gains too. But it has such a strong lipolytic effect that it helps people get rid of stubborn fat while retaining muscle growth.

Anvarol is the legal alternative to Anavar, by the way. Anavar is the steroid of choice for thousands of fitness models and female bodybuilders. The big draw is that it produces very dry and lean muscle tissue, with excellent vascularity.

But any oral C17 AA steroid is metabolized by the liver and hence, can be extremely liver toxic. Anvarol, however, is a completely natural steroid that mimics the positive effects of Anavar without any negative side effects.

You can retain lean muscle, it will help with stripping body fat, gain strength and look ribbed with Anvarol, without worrying about your cholesterol levels.

Click here for Anvarol Best Price at Official Website

Winsol is the legal alternative to Winstrol or Stanozolol. This powerful steroid is often preferred to other C17-AA oral steroids because it provides muscle gains, offers great increment in strength, and does not lead to bloating or water retention.

However, Winstrol can only be used for short bursts of time because it can damage your liver severely if abused. Winsol, on the other hand, has no side effects at all. It does not aromatize or convert to DHT, which means that it won't have any negative impact on your sex drive either.

Winsol is the perfect replica of Winstrol. It is the steroid of choice if you are looking for an aesthetic physique, muscle gains, with very little water retention, great pumps, amazing strength gains, and excellent vascularity.

It is also the perfect product for athletes who need to stay under a certain weight limit, or anyone looking for that hard core workout without looking bulked up.

Click here for Winsol Best Price at Official Website

Last but not the least, we have Trenorol, the legal replica of Trenbolone. We are sure that you have heard great things about Tren. It has attained legendary status in the world of bodybuilding.

But what you do not hear is how toxic and serious the side effects of Tren can be. Trenbolone is a potent drug, and should not be taken by recreational lifters. Period.

However, if you want to get the results of Trenbolone, without going bonkers, then you should consider taking Trenorol instead. It has all the benefits of Tren with zero risks.

Your endogenous levels of Testosterone will peak, changing the way your body produces and repairs lean muscle tissue. You will make great muscle growth, simultaneously with a metabolism boost, which leads to accelerated body fat loss as well. This means that you can take Trenorol for cutting too.

Your lifts will increase in number and weight. You also get amazing muscle pumps during the workout.

Click here for Trenorol Best Price at Official Website

Steroids are a shortcut to muscle gains. But what if you want to cut short the time it takes to build your dream physique, even with steroids?

That's where Crazy bulk's stacks come into the picture.

Steroid stacks are a combination of different steroids that are tailored to provide different effects for specific fitness goals. For instance, the Growth hormone stack combines strong endogenous hormone boosters.

While you can stack any number of Crazy bulk steroids since they work in synergy, here are the two most popular ones for your consideration.

Some legal steroid users have used single runs of the bulking legal steroids mentioned above and hit a plateau. Well, we are talking about natural supplements here and there's only so much it can offer.

If that describes you, then stacks will help you blast through the plateau. The bulking stack contains four of the most potent mass building steroids of all time.

That's the most explosive combination of steroids you can ever use. Don't think that you will only gain mass with this. You will also gain strength, cut body fat, and look ribbed. It's a whole body transformation.

2- The CrazyBulk Cutting Stack

The Crazy Bulk cutting stack is a combination of four potent legal cutting steroids. Just like the bulking stack, the cutting stack is a versatile blend that can do so much more than mere fat loss.

Here are the supplements included in this stack.

If you are looking for a shortcut that will help you get in prime shape in a span of weeks, this is it. The Cutting Stack is the ultimate way to get peeled and beach-ready without jumping through hoops.

Does Crazy bulk only offer steroids?

No. They also offer a variety of other supplements including Whey protein powder. It's just that steroids are the most popular.

Here are some others that might interest you, other than the steroids and the cutting stack.

HGH-X2 is an all natural human growth hormone (HGH) booster. Crazy bulk's expertise in endogenous hormone optimization comes through in HGH-X2 as well. It is very difficult to come across legitimate GH booster folks. HGH-X2 is one of the best legal human growth hormone (HGH) boosters on the market.

It produces a sustained increase in your GH pulses and works by stimulating your pituitary gland. The best part is that HGH-X2 does not come with some of the adverse side effects associated with synthetic HGH. You will notice a marked improvement in recovery, muscle mass gain, fat burn, and the appearance of wrinkles.

HGH-X2 is also the perfect steroid to stack with other steroids, to create a growth hormone stack.

A lot of people get gynecomastia or enlarged male breast tissue due to increased levels of estrogen in their bodies. This typically happens when you hit puberty, but it can also result due to the use of steroids like Testosterone. Gynectrol is specially designed to remove this stubborn layer of chest fat from your breast tissue.

Continue reading here:
CrazyBulk Reviews 2022: How Good Is the Legal Steroids Brand? - Cleveland Scene

7 of the Best Small-Cap Stocks to Buy Before 2022 – InvestorPlace

Posted: December 19, 2021 at 1:52 am

Following the initial devastation of the coronavirus pandemic, the U.S. economy has so far engineered an impressive recovery. Although not every metric is perfectly aligned, we can say this much: the early (and understandable) prognostications of doom and gloom did not materialize. However, with so many unknowns heading into 2022, investors may want to adjust their capitalization strategy. Here, were going to discuss ideas for best small-cap stocks to buy.

Why downsize your investment opportunities? First of all, many people have long operated under the thesis of the small-cap effect or the tendency for smaller publicly traded companies to outperform their large-cap counterparts over time. Early this year, the Wall Street Journal provided some contextual evidence for this phenomenon, noting that the best small-cap stocks within the S&P 500 index did indeed outperform their larger rivals.

Another reason to consider downsizing is what Id term the George W. Bush effect of lower expectations. Heading into his presidential debate with former Vice President Al Gore, Bushs team attempted to raise expectations so high for Gore while downplaying them for Bush. A similar situation is going on with large caps as many want to see even more robust growth from them. That might not happen, though, boosting the best small-cap stocks.

Further, everyone thats following the market knows that initial public offerings became, well, endemic in 2021. From traditional offerings to direct listings to special purpose acquisition companies (SPACs), weve seen it all and then some. However, the record year for IPOs may produce an unintended consequence. Mainstream investors are overwhelmed with flashy opportunities, while the best small-cap stocks are flying under the radar, waiting for their turn to shine.

Finally, smaller companies may be able to respond quickly and adapt to shifting market conditions. On the other hand, large-cap firms must answer to powerful stakeholders who may hinder necessary change. Therefore, as we greet the new year, dont forget to consider these ideas for best small-cap stocks to buy.

Of course, nothing in the market is without risk. While the best small-cap stocks may outperform blue chips over time, when circumstances turn volatile, smaller tends to be a liability. Primarily, this is because they lack the resources of larger enterprises. Thus, due diligence is always critical.

Typically, analysts regard small caps as companies that feature a market cap between $300 million to $2 billion. In that context, Im cheating a tad bit with CommVault Systems, which at time of writing runs a hair over $3 billion. Nevertheless, CommVault is listed on many articles of best small-cap stocks, including exchange-traded funds (ETFs) focusing on this subsegment.

But thats not the main reason Im including it here. Rather, the company, which specializes in data protection and data management solutions, is incredibly relevant. For instance, lost data from cyberattacks can cost enterprises millions. Further, smaller organizations that participated in last years grand telecommuting experiment may be at higher risk if their employees dont practice proper security measures.

As well, even the biggest firms can suffer significant damage due to outages and other unforeseen incidents. Therefore, with so much valuable assets transmitting across digital lines, its more imperative than ever for corporations of any size to protect themselves. This dynamic makes CVLT one of the best small-cap stocks to buy, regardless of whatevers lying around the corner in 2022.

More of a traditional small-cap firm with a time-of-writing market value of $557.5 million, ANI Pharmaceuticals specializes in the development, manufacturing and marketing of high-quality branded and prescription generic drugs. Obviously, the pharmaceutical space enjoyed significant attention mostly due to the Covid-19 treatment and vaccination race. With much of that fervor fading, though, ANI can shine in a post-pandemic environment.

Should omicrons higher transmissibility (but less severe symptoms) profile be indicative of the twilight of the Covid period, resources will again shift back toward non-pandemic-related healthcare needs. Further, prescription generics should play an important role in the post-pandemic era. If theres anything that we can rely on, its that healthcare costs seemingly have an exclusive directional trajectory, up.

Moreover, I like companies where the insiders believe in their business, enough so that theyre buying up additional equity. No, insider buying isnt the be-all, end-all for best small-cap stocks. However, its an encouraging sign that since 2020, the transactions that have occurred are buys, not sells. So, if youre the practice-what-you-preach type, you might want to consider ANIP.

Let me caveat the idea of including Endo International on your radar of best small-cap stocks to buy with a warning: This is not going to be any easy opportunity. On a year-to-date basis, ENDP stock has shed 42%.

On the positive side, the red ink means that the market cap for Endo is $1.09 billion, which means its no longer on the borderline of what would be considered a small-cap firm.

But is it one of the best small-cap stocks to buy? As the top holding of the Invesco S&P SmallCap 600 Equal Weight ETF (NYSEARCA:EWSC), plenty of folks at a much higher paygrade than me certainly think so. And as I mentioned earlier with ANI Pharmaceuticals, as the Covid-19 period fades into the rearview mirror, Endos specialty in generics and specialty-branded pharmaceuticals should help lift ENDP stock.

But heres something uniquely intriguing. One of Endos products is Testopel, a testosterone replacement therapy. According to a report published on ScienceDaily, a study of patients hospitalized due to COVID-19 suggests that the disease might deteriorate mens testosterone levels.

Further, many male Covid patients reported loss of libido. Cynically, then, ENDP should rise to the occasion.

As a recent uplisting from the over-the-counter market to the Nasdaq exchange, I consider Ranger Oil Corp a spiritual IPO. True, on paper, an IPO represents the first time a company distributes its equity shares to the public. On the other hand, an uplisting from the pink sheets to a proper exchange is more of an introduction to a wider audience.

But isnt that one of the main points about an IPO? After all, privately held enterprises can raise funds through venture capitalists and other means. However, going public allows firms to reach the widest audience possible, netting the largest raises possible (all other things being equal). So with Ranger Oil being a Nasdaq play, I have higher expectations for it in 2022.

Still, some might question its inclusion on a list of best small-cap stocks to buy considering that the oil and gas business is losing sentiment against renewable energy firms. In recent years, renewables have become much more economically viable due to rising technology and lower costs.

However, the high energy density of fossil fuels means they could be surprisingly relevant for many, many years to come. Therefore, if youve got some loose change, you might want to put it to work with Ranger Oil.

Customers Bancorp is a perplexing idea among best small-cap stocks and not just because Im again playing a little loose with the definition of small. At a few ticks under $2 billion, Customers Bancorp may be poised to enter the mid-cap range fairly soon.

And that notion isnt out of the question. CUBI stock has been a high-flyer in 2021, gaining almost 218% since the January opener. Since Im not the biggest fan of buying into strength after a particularly robust rally, Im personally a bit hesitant on the opportunity.

Nevertheless, some folks might be encouraged with the outsized performance. Certainly, the companys fundamentals justify the premium. For instance, in the first three quarters of this year, Customers Bancorp has already rung up $548.9 million on the top line, exceeding 2020s results by 9.3%.

To be clear, 2020 wasnt a down year for the company, which saw total revenue increase nearly 41% over 2019s result. So, the firm is on a tear.

Whats interesting about Customers Bancorp is that one of its subsidiaries is building a cryptocurrency infrastructure to better serve its clients. Thats the kind of smart, innovative thinking that will make CUBI possibly more relevant than the competition.

Another high-momentum play among the best small-cap stocks to buy, Ill leave it to you whether you want to acquire shares of Arlo Technologies a wireless smart home security system provider into strength or hold out for a better price. Over the past six months, ARLO gained 31% while in the trailing month, its up 16.5%. Most of those gains occurred in the prior five days, up nearly 13%.

However, like other names among the best small-cap stocks, Arlo justifies its momentum through strong financial performances. During the first three quarters of this year, the company generated revenue of $292.3 million. Considering that 2020 sales amounted to $357.2 million, Arlo only needs a modest tally in the fourth quarter to beat out the prior years result.

Heck, a modest tally should be enough to eclipse 2019 sales, which was $370 million.

Most importantly, though, the outside fundamentals are cynically supportive of ARLO stock. For instance, weve been hearing news reports about San Franciscos brazen property crime spree. Apparently, tolerance for such behaviors is dimming, playing into Arlos hands.

My riskiest and most audacious name among best small-cap stocks, Im going to urge you to perform your own due diligence with KAR Auction Services. Believe me, my feelings will not be hurt if you think this idea is garbage. As the corporate brand entails, KAR Auction provides vehicle auctions and related vehicle remarketing services. Thus, the obvious question is, why?

After all, weve seen an absolutely bonkers season for used car prices. Out of nowhere, buying a car any car during the pre-pandemic period was now a great investment. As you know, this runs counter to the common logic (actually fact) that unless youre buying a truly distinct vehicle, mass-produced vehicles almost always lose their value.

However, as much as people would like to think that car prices are on the cusp of falling, so far, theyve been rising. Indeed, a recent Fortune article bemoaned that rates in the secondhand market keep going higher. Surely, the madness will end in 2022?

Well, maybe not. You see, the computer chips that go into vehicles are of a cheaper, lower-margin variety. Therefore, semiconductor firms would much rather prioritize the consumer-electronics industry, which are much more lucrative.

As much as I hate to say it, KAR could very well be one of the best small-cap stocks to buy for 2022.

On the date of publication, Josh Enomoto did not have (either directly or indirectly) any positions in the securities mentioned in this article.The opinions expressed in this article are those of the writer, subject to the InvestorPlace.comPublishing Guidelines.

A former senior business analyst for Sony Electronics, Josh Enomoto has helped broker major contracts with Fortune Global 500 companies. Over the past several years, he has delivered unique, critical insights for the investment markets, as well as various other industries including legal, construction management, and healthcare.

More:
7 of the Best Small-Cap Stocks to Buy Before 2022 - InvestorPlace

Sports trans issue is here to stay. But at last, the debate is starting to change – The Guardian

Posted: December 19, 2021 at 1:52 am

It is funny how times change. The Guardian has obtained a letter, written in 2003 by Dr Richard Budgett, in which he discusses the consequences of trans women competing in womens sport. Responding to a government inquiry, Budgett, then at the British Olympic Association, states: The effect of allowing male transsexuals to compete as women would be to make competition unfair and potentially dangerous in some sports and would undermine womens sports.

This would have been an interesting answer at the time. It is even more so now. Society has shifted. Language has changed. Budgett is now medical and scientific director at the International Olympic Committee. And his views, according to IOC sources, have evolved particularly when it comes to finding ways to balance the need for inclusion and fairness in sport. A controversial new IOC framework, drawn up in part by Budgett, adopts a strikingly different stance. While stressing that mens and womens competition should be fair and safe, it also tells sports that, until evidence determines otherwise, trans athletes should not be deemed to have an unfair or disproportionate competitive advantage.

Yet the ink had barely dried on that framework document when the US college swimmer Lia Thomas caused a fresh splash in the debate. For her first three years at the University of Pennsylvania the 22yearold swam as a male competitor, making six Ivy League swimming finals though not setting the world alight. But in the past month, competing as a trans woman after taking hormone replacement therapy to lower her testosterone, she has swum the fastest 200- and 500yard times in the US this year.

That, though, tells only half the story. Thomass 200yard time of 1:41:93 ranks as the 17th fastest of all time less than three seconds off the fivetime Olympic medallist Missy Franklins US record of 1:39:10. Meanwhile her 500yard time of 4:34:06 puts her 21st in history and within striking distance of a record set by Katie Ledecky, who is widely regarded as the greatest female swimmer in the sports history.

All roads now lead to the NCAA championships in March, where Thomas could become swimmings first transgender All-American champion. It will be a significant moment for sport and for Thomas, who last week stressed how important it was for her to swim as her authentic self and praised the IOC for promoting inclusivity while keeping competition integrity going.

Others, though, are less happy. According to reports, Thomass teammates were in tears with one explaining: They feel so discouraged because no matter how much work they put in it, theyre going to lose. Meanwhile Swimming World magazines John Lohn said he was uneasy that Ledeckys record was under threat. Simply, she is an icon who changed what was perceived to be attainable, he wrote. The fact that Thomas could break the record of such a onceinageneration athlete confirms the biological advantages she possesses, and their power,.

Thomass surge to the top of the rankings also poses questions of the IOC and NCAA. Remember the female category exists because the performance gap between elite men and elite women is so stark. It starts at around 10%-13% for running and swimming and rises thereafter. That is why most sports require trans women to suppress their testosterone to compete in the female category.

Recent studies, though, suggest that significant strength and muscular advantages remain even after hormone therapy. Thomass performances appear to back that up. Before transitioning, she was not a serious challenge to male records but is now swimming only 2.6% slower than the current 200yard female record. It means, as the developmental biologist Dr Emma Hilton points out, Thomas has gained a significant ranking advantage from switching category.

Is this unfair? In 2003 Budgett thought so. As he put it in his letter: The BOA believes the effect of allowing transsexuals to compete in their acquired sex would be to make competition unfair for women. The physique determined by two or more decades of life as a male would not be significantly changed (in the case of male to female transsexuals) which would eradicate the concept of a level playing field.

Some will argue that sport is never truly fair, that Michael Phelpss big wingspan gave him genetic advantages too. But male puberty provides such a categorical advantage in terms of muscle mass, strength, lean body mass and bone density that it far exceeds the advantage of a few centimetres in arm length.

No magic bullet, no one-size-fits-all policy can satisfy all sides. The issue involves competing rights and strong emotions. Worryingly a recent UK Sports Councils Equality Group report also found that women in sport were told to keep quiet by their national governing bodies and feared abuse on social media if they voiced their opinions.

Yet perhaps times are changing. At the Sport Resolutions dispute resolution service last week several experts were able to discuss openly and courteously what sports should do next. It made for fascinating listening. For David Grevemberg, of the Centre for Sport and Human Rights, inclusion mattered most. And if sport had to radically change, then it should. Are there ways, that are not infringing on human rights, to create a level playing field? he asked. Are there other conditions that we can create for example staggered starts in the 100m? Or delayed starts?

Thank you for your feedback.

Meanwhile Joanna Harper, a visiting fellow at Loughborough University and a trans woman, argued for a similar approach to the IOCs 2015 guidance but with trans women required to reduce their testosterone to below five nmol/L for at least 12 months. She said the advantages were small enough that trans women and cis women can have equitable and meaningful sport.

However, for Dr Nicola Williams, a spokeswoman for Fair Play For Women, the best solution would be for men to budge up and be more inclusive by allowing trans women and trans men into an open or universal category, with a separate category exclusively preserved for natal females.

Whatever your view, one thing is clear: this issue is not going away. And Thomass groundbreaking performances have only made that clearer to Richard Budgett, the IOC and the rest of us.

Here is the original post:
Sports trans issue is here to stay. But at last, the debate is starting to change - The Guardian

With My Body, I Thee Worship: Part Two – Patheos

Posted: December 19, 2021 at 1:52 am

Go here for Part One.

Content Warning: This post contains discussions of medical and sexual abuse of children. Please read with caution.

Dr. John Money was a psychologist and researcher at Johns Hopkins. He did a lot of research into gender and sex, both medically and sociologically, and invented a number of terms and ideas we now associate with both. However, his reputation is not, as the saying goes, great. He was involved with a number of experiments in performing gender-related surgeries on infants, the most infamous being the case of David Reimer.

David Reimer, date unknown

Reimer was born in 1965, one of a pair of twin boys. A botched circumcision destroyed his penis as an infant. Money spent decades championing the idea that gender identity is primarily learned. He persuaded Reimers parents that it would be better for him to receive further surgeries and be raised as a girl (Brenda). They did so. And Moneys involvement didnt stop there. During subsequent appointments with the twins, he forced them to strip for genital inspections (sometimes taking pictures) and to engage in sexual play, claiming that such childhood rehearsals were essential to develop a healthy adult gender identity.1 He trumpeted what he called the John/Joan case as proof positive of his theories about gender being more a result of nurture than nature.

Unfortunately for the victims of this disgusting quack, he was wrong. By age eleven, Brenda had a strong sense he was not a girl, despite regular estrogen injections and female puberty. Finally, in 1980, the Reimers told Brenda the truth. He promptly took on a male identity (including the name David) and began to receive testosterone injections and masculinizing surgeries. No amount of female socialization or hormone replacement therapy had been able to efface his inner sense of who he was.2

Now, I expect a lot of anti-trans readers (Catholic or not) will be nodding along sagely to all of this. You cant fight nature. You cant just decide to be a different gender. Try, and it will take a terrible toll, perhaps a deadly one. This is why all this gender ideology stuff is so dangerous.

But is that really the lesson here? Because if it were that simple, gender transition should produce far greater misery than the dysphoria its meant to treat. But thats not what the evidence shows: on the contrary, transition is the only recognized treatment for adult dysphoria in modern medicine.3 Opponents of gender ideology love to cite detransitioners (people who transitioned to another gender and later changed their minds) as evidence that transition is bad and dangerous, but if anything, they prove the opposite.4 Only a tiny percentage of people whove transitioned pursue detransition, and of those, an even smaller fraction claim to do so out of regret. Most cite factors like prohibitive medical expenses and family rejectionnot a keen inner sense that they were and remain their old gender.

The actual experiences of trans people line up far more with David Reimers than with the lives of cisgender5 people. Theyre usually raised and socialized according to their birth sex; most experience all the normal hormonal changes of puberty. Yet none of this effaces the sense, which they often have from an even earlier age than Reimer, that their gender is not the same as their physical sex. Could any serious person claim that these peoples minds have been changed by a fad? When both nurture and nature have been working to settle them since infancy?

And whats even more ridiculous about all this is, we just did this. We spent the 1980s, 1990s, and 2000s trying out the whole ex-gay narrative. And in 2013, the largest ex-gay organization in the world shut its doors and its leader issued a public apology for the harm hed done.

Does it follow that transgender issues are just like homosexuality? No. But can we at least not rush to make all the same assumptionsthat being trans is a psychological disorder, that its the parents fault for not nurturing the child right, that its curable with the right therapy, that people are doing it for attentionthat just gave us such a colossal series of embarrassing disasters? Can we please stop for five damn minutes and actually look at the research thats been done about this, instead of pretending we must have the answers already because the Church is infallible?

Its no insult to the Church to suggest that she hasnt yet answered a question that simply hadnt been raised before. And its no compliment to suppose that she is incapable of handling new questions. The modern concept of being transgender has antecedents in cultures all over the world, yes. But as far as I can tell, it hasnt been posed in exactly this form before, or with the same scientific resources to help answer it we have today.

Worse still, were not even done with Money. Because he didnt start his career of experimenting on the bodies of helpless infants in 1965. His career goes further back, and gets into the correction of the bodies of intersex people.

And whats intersexuality? I am, both sarcastically and sincerely, glad you asked.

Part Three to come.

1I expect it will come as no surprise to anyone that, while allowing that it could be sadistic, Dr. Money considered affectional pedophilia to be perfectly healthy as well.

2Reimers life, I am sorry to say, remained tragic. He continued to struggle with mental problems throughout his life, as did his brother, who died of an overdose in 2002. In 2004, at age 38, Reimer took his own life. The twins parents consider Dr. Money responsible for both deaths; he himself died in 2006.

3I specify adult here, because gender dysphoria in children does seem to weaken or fade completely at puberty in some cases. However, the research on this is stillno pun intendedin its infancy. It is also true that some adults choose to manage dysphoria, rather than treating it through transition; this doesnt change the fact that managing a condition isnt the same as treating it.

4More realistically, they prove neither: studies of detransition are few as yet, and many have small sample sizes that limit their usefulness.

5Cisgender means a person who identifies with the gender of their birth sex.

Read more here:
With My Body, I Thee Worship: Part Two - Patheos

23-year-old diagnosed with cancer, says doctors dismissed her cough – Insider

Posted: December 19, 2021 at 1:50 am

When Chloe Girardier developed a cough in July, she thought it was a cold. But when it persisted, she sought a doctor's appointment. At first, she said, she was denied.

"They kept telling me I wasn't eligible for an urgent appointment because it was just a cough," Girardier, a 23-year-old home health worker in the UK said, according to The Sun. They kept asking her if she'd taken a COVID test without considering other possibilities, she said.

Eventually, Girardier said, she was given antibiotics , inhalers, and acid reflux tablets, but her symptoms didn't change. They were getting worse: Girardier said she was losing weight, too.

After five months and seven doctors appointments with no answers, Girardier said she insisted on a chest X-ray.

The scan revealed a 4.25-inch mass in her chest that turned out to be Hodgkin's lymphoma. The rare cancer causes cells in the lymphatic system grow abnormally and sometimes spread. It can cause a persistent cough, unexplained weight loss , and fatigue, among other symptoms, the Leukemia and Lymphoma Society says.

Girardier is set to undergo intensive chemotherapy on December 20.

"I can't believe it wasn't looked into further and if I hadn't pushed for the chest X-ray, I may still not have a diagnosis," she said. She's speaking out to encourage young people to listen to their bodies.

"It's been dragged on so long because of my age," Girardier said.

Researchhas found that women report more severe levels of pain, more frequent pain, and longer periods of pain than men, but are treated for it less aggressively. One2018 surveyfound 62% of women have felt dismissed by a male doctor compared to 42 percent of men. When visiting female clinicians, 47% of women feel dismissed and 37% of men do.

Those slights can be dangerous.

24-year-old Danielle Soviero was diagnosed with a brain tumor that had hemorrhaged and yet she says she was sent home and told to live life "as normal." Over six months latershe experienced a debilitating migraine and a "strange pressure" in her head and demanded an MRI.

Even after the scan revealed the tumor had doubled in size and hemorrhaged again, the doctor said it couldn't be removed, Soviero said.

"I was angry. I decided that I needed to take matters into my own hands," Soviero told Insider. She found a surgeon who removed the tumor, and after months of occupational, physical, and speech therapy, is almost back to her old self.

Another young woman,Brittany Scheier, previously told Insider her symptoms were brushed off in the ER as drug- or alcohol-related. She was later diagnosed with a stroke at age 27.

Another womantold Insider that herbirth-controllinked blood clot was also dismissed as alcohol or drugs at age 15. AndTikTokers, including one pregnant woman whose stroke was misdiagnosed as dehydration, have encouraged others to speak up for themselves.

Dr.Suzanne Steinbaum,a cardiologist in New York City, previously told Insider she often hears women say "I was listening to the doctor. Maybe they're right,'" she said. "No one knows our bodies as well as we do. Nobody is living in our bodies. We know when we're not OK."

Read more:
23-year-old diagnosed with cancer, says doctors dismissed her cough - Insider

Restore IV drip therapy relieved muscle soreness with vitamins, acids – Business Insider

Posted: December 19, 2021 at 1:50 am

IV drips are the latest health trend to move from hospitals to boutique wellness clinics.

Though hospitals have used intravenous drips to hydrate patients and quickly administer drugs since the 1970s, today's wellness brands popularized using IV drips to cure hangovers and give health-obsessed clients a quick boost of vitamins, minerals, and supplements.

Analysts at BCC Research expect the global market for IV therapy to reach $54.5 billion by 2023.

I sought to find out if IV drip therapy is worth the hype. I visited Restore, a wellness brand that offers a variety of IV drip therapies it says can help with weight loss , hydration, energy, inflammation, and aging.

I went to Restore's location in the Chelsea neighborhood of New York City at 12:45 p..m. Two others were receiving IV drip therapies while on their laptops, and a third received compression therapy meant to reduce muscle pain.

When I got to the wellness center, I had to fill out a few forms that asked about my medical history. The forms had extensive questions about history of complications related to my brain, heart, lungs, eyes, mental health, liver, kidneys, and more.

After filling out the forms, a nurse set me up on a Zoom call with a nurse practitioner to review my forms. The wait to talk to a nurse practitioner only took about five minutes, and the call lasted about another five because I had no history of medical conditions.

I then selected which supplements, acids, and vitamins I wanted in my IV. I chose the "Recharge" drip that Restore claimed would restore energy, promote collagen production, help with muscle repair, and aid in the excretion of metabolic waste.

The drip cost $209 for non-members. Drips ranged between $139 to $339 for non-members, and patients can choose to add extra shots and supplement boosts for $35 to $39.

The "Recharge" recovery drip therapy I selected included four ingredients: proline, an amino acid used as the building block of proteins; taurine, an amino acid the body uses as an antioxidant and a metabolite; vitamin C, which controls infections and helps heal wounds; and glutathione, which helps form and maintain disulfide bonds in proteins.

I chose Recharge to help me recover from a high intensity workout from the morning. Even though I usually feel the most soreness in my muscles the day after a heavy weight exercises due to a phenomenon called delayed onset muscle soreness I could already feel weakness in my muscles a couple hours after leaving the gym.

After selecting my drip, I got to select to sit on either a massage chair or a recliner. After sitting down, Kierstin Wood, a nurse at the center, brought over the IV and needle.

Though I used to be good with needles, the last time I got my blood drawn I had to get poked four times because the nurse could not find my veins. I was nervous the same might happen this time around, but Wood inserted the needle with ease within a couple seconds.

As I got my IV drip placed, Darren Mota, the general manager at Restore's Chelsea location, talked about other therapies offered at Restore, including cryotherapy, compression therapy, hyperbaric oxygen therapy, and infrared saunas.

Miriam Rammal, a Restore nurse, said customers have used hyperbaric chambers, which increases air pressure to allow your lungs to breath more oxygen, for recovering from surgery, treating COVID-19 brain fog, and sleeping.

Mota, a former Nike coach, said Restore's various therapies have helped him recover from exercise much faster than before he started using them. Mota said he can work out everyday, and sometimes twice a day, due to decreased time he spends in recovery.

The IV therapy took about 35 minutes total. After the drip, I felt slightly lightheaded and nauseous, so the nurses recommended I sit for five minutes.

As I recovered, I asked Rammal and Wood about working at Restore. The nurses spend most their time working at Lennox Hill helping long-term intensive care patients and work at Restore part-time.

The two had both treated COVID-19 patients during the height of the pandemic, when New York City was the epicenter of the new disease. Rammal and Wood said helping healthy, fit people at Restore offered a welcome break from treating severely sick patients.

As I was recovering from the drip, I started to feel more alert, like after having a cup of coffee. Importantly, my muscle soreness was gone entirely it was like I hadn't even worked out that day.

I was curious to see if Restore could help with my DOMS the next day, but unfortunately my muscle soreness came back. It would be nice to get another IV drip to relieve my soreness, but I can't afford another $200 treatment.

Originally posted here:
Restore IV drip therapy relieved muscle soreness with vitamins, acids - Business Insider

The #1 Worst Breakfast Habit for Weight Loss Over 40, Says Dietitian Eat This Not That – Eat This, Not That

Posted: December 19, 2021 at 1:50 am

When you're trying to lose weight in your 40s, it's important to make sure your habits are aligned with your goals. This includes your eating, drinking, and exercise habits. That's why, according to Stephanie Gomez, RD at Sporting Smiles, one of the worst breakfast habits you can have for weight loss is not eating enough in the morning, or skipping breakfast altogether.

"For the sake of saving calories (or time), many adults will skip breakfast or have something small like a piece of toast, a low-fat yogurt, a piece of fruit, or just stick with coffee and creamer alone," says Gomez. "But the habit of such restriction in the morning is a recipe for disaster for the rest of the day."

While this may seem like a solution for weight loss, limiting your caloriesor not eating anything at allcan actually have a negative effect on your overall health.

RELATED:Get even more healthy eating tips straight to your inbox by signing up for our newsletter!

"A common misconception about losing weight is that calories in versis. calories out is the 'end all be all' in the conversation about weight loss, says Gomez. "But the limited concept of caloric balance does not take into consideration any of the metabolic processes that come into play every time we eator don't eat."

In other words, when you skip breakfast in the morning, you may assume that you'll lose weight because it's fewer calories going in. However, skipping meals can do damage to your metabolism, which can ultimately hinder your weight loss goals.

"When we eat breakfast we are setting our metabolism into motion for the day, 'fueling the fire' so to speak," says Gomez. "If we skip breakfast, we are beginning our daily activities without sufficient energy to support them. A lack of food in the morning can cause lethargy, poor mood, and poor impulse control, which is ultimately going to lead to some poor choices for the rest of the day."

According to Gomez, you want to avoid breakfasts that are strictly made up of carbohydrates because your body will burn them too quickly and you'll be left feeling hungry shortly after.

"The right answer is to eat a breakfast that contains some carbohydrates, some protein, and some fat to leave us feeling energized and satisfied so that when lunchtime rolls around, we can make another sound choice because we won't be left feeling starved," says Gomez.

Her recommendations for a well-rounded, fulfilling breakfast? Gomez suggests trying "oatmeal with some berries and soy milk, or egg whites with spinach and a piece of whole-wheat toast."

For even more breakfast tips, read these next:

Read the original here:
The #1 Worst Breakfast Habit for Weight Loss Over 40, Says Dietitian Eat This Not That - Eat This, Not That


Page 183«..1020..182183184185..190200..»