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Following the Mediterranean diet can improve consumers’ heart health, study finds – ConsumerAffairs

Posted: December 4, 2020 at 11:56 pm

Photo (c) Fascinadora - Getty ImagesFollowing a healthy diet has been found to be a key component of optimal heart health. Now, experts from the University of Crdoba are encouraging consumers to consider the Mediterranean diet -- which prioritizes fruits and vegetables and healthy fats -- to improve overall heart function.

According to their findings, following the Mediterranean diet can be effective at both boosting cardiovascular health and reducing the risk of a heart attack.

We observed that the Mediterranean diet model induced better endothelial function, meaning that the arteries were more flexible in adapting to different situations in which greater blood flow is required, said researcher Jos Lpez Miranda. Besides, the endotheliums ability to regenerate was better and we detected a drastic reduction in damage to the endothelium, even in patients at severe risk.

The researchers divided 1,000 participants with heart disease who had experienced a heart attack into two groups to determine which one of two diets was more effective in improving heart health outcomes. One group was instructed to prioritize low-fat foods, which included reducing their consumption of sweets and red meat while also incorporating more carbs. The other group followed the Mediterranean diet, which also eliminates red meat but places an emphasis on fruits and vegetables, whole grains, fish, and olive oil.

After one year, the researchers assessed the participants heart health based on several different outcomes. They learned that adopting the Mediterranean diet was more effective than the low-fat option in improving overall heart health. It also reduced the participants risk of having a subsequent heart attack and reduced lasting damage to the heart by improving overall heart function.

The researchers are excited about these findings because they show that taking action early in the fight against heart disease can have long-term benefits for consumers.

The degree of endothelial damage predicts the occurrence of future cardiovascular events, as in acute myocardial infarctions, said Lpez Miranda. If we can take action at the initial stages, prompting endothelium regeneration and better endothelial function, we can help to prevent heart attacks and heart disease from reoccurring.

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Following the Mediterranean diet can improve consumers' heart health, study finds - ConsumerAffairs

Rebel Wilson Reveals Her Diet Secrets, Battle With Emotional Eating and More After Shedding 61 Pounds – Us Weekly

Posted: December 4, 2020 at 11:56 pm

After reaching her goal weight in 2020, Rebel Wilson is revealing how and why she decided to get serious about her health.

Its been, like, a little bit over a year from when I first started and I want you to, first of all, know that Im not frickin perfect about it, the 40-year-old actress began on Tuesday, December 1, via Instagram Live. Its not like Ive had some incredible discipline and Im just, like, every day restricted or worked out like a beast. I mean theres been days where Ive done that, but it certainly hasnt been all the time. What Im more focused on is balance.

During her lengthy Live, Wilson detailed her triangle of health, which included tracking her physical, nutritional and emotional health.

Nutrition was, like, a big deal because you cant out-train a bad diet, which is something that I shouldve known, but really didnt know this year, the Isnt It Romantic star explained. What Ive had to do is really look at what Im eating. Im someone who grew up eating fast food several times a week. Pizza Hut, McDonalds, which is so tasty, its nothing against those companies. Oh, my God, In-n-Out Burger in L.A., love it. But the problem is, I was eating it way too often and I have a real sweet tooth as I was just saying and basically, I only used to eat, like, carbs and sugar.

Earlier this year, Wilson announced her ideal weight was 165 pounds. After she stepped on the scale on Saturday, November 29, she revealed she accomplished her goal and dropped more than 60 pounds.

The goal was never to be skinny, it was never to fit into a certain dress size. I put a goal weight on there because I needed some tangible thing, she explained on Tuesday. But Ive also done some body measurements and stuff like that as well, so the weights not the only thing. But I am really glad that I did it because I think it was time. Ive been overweight for about 20 years and I love playing some of the comedic characters like Fat Amy from Pitch Perfect and everything. I love all that stuff but at a certain point, I knew in my heart that I was engaging in some unhealthy behaviors and that I needed to change those for the better and so what Im proud of myself for is for doing that and having a lot more balance now in my life.

While Wilson admitted that there were people in her life who didnt want [her] to change, boyfriend Jacob Busch wasnt one of them.

At the end of the day, its about balance and being a better version of me. This year, in a global pandemic, one of the most important things is health, she noted. Because if youre healthy and you have a strong immune system, youre less likely to be susceptible to the virus or serious complications and your health is so important.

Scroll through for the biggest revelations from Wilson:

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Rebel Wilson Reveals Her Diet Secrets, Battle With Emotional Eating and More After Shedding 61 Pounds - Us Weekly

How to Lose 20 Pounds In 2 Weeks: Effective Plan to Lose …

Posted: December 4, 2020 at 11:54 pm

If you want to lose 20 pounds in 2 weeks, then its essential that you have an effective and healthy plan for rapid weight loss. Losing weight quickly can help you to kick-start a long-term diet plan if you need to quickly shed weight and then keep off extra pounds. As with any effective diet plan to lose extra fat from your body safely, you need to take into consideration your own health. That is why the best ways to lose weight fast should combine lifestyle changes, exercising, and being physically active.

Having the goal to lose 20lbs in a couple of weeks is certainly a good goal to have if you are overweight and have weight-related health issues. However, it is not always a good idea to try and lose a large amount of weight in just two weeks, so you may need more time for that. Rapid weight loss can take a toll on your health and cause other unwanted health complications. Therefore, if you plan to use a fast weight loss program, you should speak to a qualified medical professional.

In this article, you will find out how to lose a lot of weight in the shortest time possible. You will find out healthy ways to help shed extra pounds in no time at all and you may already start to look slimmer within a few weeks.

Extreme dieting measures could help you lose weight rapidly but you need to follow an effective plan to make sure your body gets all the nutrients it needs.

You need to realize that you didnt gain 20 pounds in 2 weeks so losing this weight in a short period of time can be a great challenge. It is certainly possible to lose 10 pounds of weight in one week but it will not be pure body fat and some of it will be water weight.

Losing 20 pounds in just 2 weeks will require a very low calorie diet which is not the best approach if you want to lose weight and keep it off.

According to the American Journal of Clinical Nutrition, very low calorie diets lead to a fast weight loss. However re-feeding after such extreme dieting leads to fast and excessive weight regain.28 The most sensible approach is to develop effective habits that will help you lose weight gradually and keep it off.

In this detailed article I am going to give you the best possible information on how to lose weight fast and keep it off. Youll learn about the most effective ways, based on science, to lose weight and develop eating habits to keep it off.

Here are the steps you need to take to lose as much as 20 pounds in 2 weeks.

One of the best ways to lose weight quickly in 2 or 3 weeks is to lower your daily calorie intake.

Lowering your calorie intake helps to speed up weight loss as you will burn more energy than you consume. To lower your calorie intake in order to lose 20 pounds fast, you can swap foods for healthier options, limit your intake of saturated fats, and eat smaller portions.

Consuming fewer calories every day will help you lose 20 or even 30 pounds at a steady, healthy pace and boost your general health at the same time. According to the National Heart, Lung, and Blood Institute, you should reduce your daily calorie intake by 500 to 750 calories per day to lose significant weight in a couple of weeks.1

Doctors from the National Health Service recommend some healthy food swaps to help lower calorie intake and lose weight faster.29 Here are some examples to help you lose as much as 30 pounds in a month:

For more information on how to tweak your diet to speed up the effectiveness of your weight loss plan, please read my article on the best hacks for speedy weight loss.

If you want to make sure and lose as much as 20 or 30 pounds in a month you should change your eating habits.

Changing your eating habits helps with rapid weight loss because it helps you develop positive habits that contribute to weight loss at a regular pace.

For example, one way to help speed up weight loss and lose unnecessary pounds is to drink a glass of water before each meal. Dr. Arefa Cassobhoy on WebMD reported on a study into the effects of drinking water and obesity. The study found that drinking 16-oz. of water 30 minutes before a meal helped severely overweight people shed extra pounds easier and faster.2

Another habit that can help to lose a lot of pounds in a couple of weeks is to start the day with protein. Starting your day with eggs for breakfast or consuming lean meat, milk, or nuts are all great sources of protein that will keep you feeling fuller for longer and give you plenty of energy. This reduces the temptation to snack during the day and helps boost weight loss in a 2 or 3-week diet program.

You can also lose weight much quicker in 2 or 3 weeks if you are careful about when and why you eat. A study published in the Journal of Occupational and Environmental Medicine found that emotional eating is associated with body weight gain. It was found that eating due to emotional responses caused people to become overweight and obese.3

There are many effective ways to beat emotional eating. These include reducing stress and anxiety, getting plenty of sleep, and eating proper amounts of dietary fiber and protein.

Eating small frequent meals will help you lose 20 or even 30 pounds faster.

Rather than skipping meals during the day, you might find that eating small frequent meals throughout the day helps you lose weight at a proper pace. However, there is some controversy whether people wanting to beat the battle of the bulge quickly should eat 3 or 6 small meals during the day.

For example, in 2015 the journal Nutritional Reviews reported that eating frequent meals seems to help people lose excess fat and reduce overall body weight.4 But, the journal Obesity found that in their study, eating 3 meals a day or 6 meals a day had no overall impact on weight loss. The report found that total calorie intake in a day was the most important factor when it comes to fast weight loss.5

So, if you are looking to lose several pounds of body weight as fast as possible using an effective diet plan, you could try to see which of these methods work best for you.

Reducing portion size should help you start losing pounds of body fat in 2 weeks.

Eating smaller portions at lunchtime and in the evening can help to reduce energy intake and help you lose weight and keep the weight off.

A study published in the American Journal of Clinical Nutrition found that when individuals ate smaller portions for lunch, their daily energy intake was reduced by 30%. The researchers concluded that eating smaller portions can help to treat and prevent obesity. The study highlighted the fact that portion sizes in restaurants are getting larger and most people finish their large entrees.25

Another study showed that one way to control portion sizes and lose weight quickly is to eat more foods that are low-density energy sources and limit high-density energy foods. For example, having more vegetables and lean protein and less fatty foods can help reduce energy intake from meals and thus help you lose weight much quicker.26

You could also try using a portion control plate for your meals at home to help you greatly reduce portion size to eat healthier meals and lose weight. You might not lose 20 pounds of body weight in 2 weeks with this method, but it is a safe and healthy way to control body weight.

To shed more pounds of body fat in 2 weeks, you should also limit your intake of unhealthy carbohydrates.

Unhealthy carbs that can make losing body weight difficult include simple carbohydrate sources such as white bread and pasta, cakes, pastries, and sugar. Low carb diets have many proven health benefits that include more than just losing weight fast.

When lowering your carb intake, you should remember not to cut out healthy carbs that are classed as complex carbohydrates. These include wholegrain bread, brown rice, whole-wheat pasta, beans, vegetables, and fruits. Dr. Kathleen Zelman on WebMD says that fiber in food helps to control weight and can lower your risk of heart disease and colon cancer.6

Dr. Zelman recommends switching to whole grains as much as possible and avoiding foods that have added or refined sugars. You should also eat plenty of fruit and vegetables every day and include beans and legumes in your diet.

You should avoid junk food and limit sugar consumption to lose weight quickly.

Junk food and foods with added sugar not only have very low nutritional value but they can make it very difficult to slim down very fast in a short period of time.

The University of Michigan reported on a study showing a correlation between fast food and increased body mass index, weight gain and obesity. The study also found that people get heavier as the number of fast food outlets increase.7

Cutting out sugary foods and sodas can also help you lose a lot of weight in two weeks. Dr. Laura Martin on WebMD says that limiting foods containing refined sugars will help a person lose weight and reduce levels of obesity.8

You can also lose several pounds quicker by increasing your daily water intake.

Drinking more water doesnt just help lose weight from around your waist but it prevents the symptoms of dehydration. Water is also one of the best ways to flush toxins out of your system and boost the health of your kidneys.

A study published in the Journal of Natural Science, Biology and Medicine reported that drinking 1.5 liters of water every day helps to reduce body weight, body fat, and body mass index. The researchers concluded that drinking water can be a useful and cheap way for obese persons to lose weight quicker.9

You dont just have to stick to plain water to lose a lot of weight in a few weeks. You can easily make your own calorie-free flavored water that will help boost your weight loss plan in 2 weeks.

To reach your goal of losing a lot of excess body weight in 2 weeks, you should also make some lifestyle changes along with sticking to an effective plan to lose weight fast. Lifestyle changes to help lose weight are just as important as reducing calorie intake when it comes to getting rid of body weight in a matter of a few weeks.

Here are 4 lifestyle changes that doctors recommend to boost the effectiveness of your weight loss plan.

While it is important to exercise regularly every week, staying active throughout the day will help to accelerate how quickly you lose weight.

A study in the journal Mayo Clinic Proceedings found that non-exercised activity thermogenesis (NEAT) can help to significantly increase calorie expenditure. It was found that NEAT movements can also protect a person from cardiovascular disease and reduce obesity in people who have difficulty exercising.10

Here are some easy ways to increase NEAT movements throughout the day and help burn fat quicker in a couple of weeks.

If you are serious about losing a lot of weight in a short space of time, then getting plenty of sleep is essential.

Although a hectic work schedule and stress can make getting to sleep difficult, there are many positive health benefits of getting proper rest during the night.

Dr. Melinda Ratini on WebMD says that lack of sleep is linked to weight gain and obesity. For example, feeling well-rested reduces food cravings and gorging on high-carb snacks. Also, getting the right amount of sleep helps to balance your hormones naturally and reduce fat by increasing your metabolism.11

To help improve your sleep patterns to stop fat accumulating in your body, here are some helpful tips to lose as much as 20 pounds in 2 weeks:

If you really want to shift those extra pounds of body weight in two or three weeks, you should find ways of reducing stress in your daily activities.

According to Dr. William Blahd on WebMD, stress increases cortisol levels in the body which can increase the desire for sugary, fatty foods. This can also increase your risk of high blood pressure, cardiovascular diseases, or diabetes.12

Dr. Blahd recommends some easy ways to deal with stress at home and increase the effectiveness of your weight-loss program:

To make sure and lose as many pounds as possible in a two-week period, it is very important to keep yourself motivated.

Having strong motivation will help you stick to your weight-loss plan even when it seems that results arent what you expected.

Doctors from the Mayo Clinic say that long-term weight loss is only achieved through making permanent changes to your eating habits and lifestyle. To keep yourself motivated to lose weight quickly and keep it off, this is what they suggest:30

When looking to lose a lot of weight in the short-term, its necessary to boost your weight-loss plan with healthy exercise. Getting regular exercise is not only good for your heart but it will help to burn even more calories.

Here are some of the best way to burn off extra body fat that has accumulated around your face, waistline, or other parts of your body.

Increasing the amount of walking you do every day will help to shed pounds from your body in no time at all.

A study published in the International Journal of Obesity and Related Metabolic Disorders reported that brisk walking for 30 minutes on most days of the week was an effective part of a weight-loss plan.13

How can you include walking as part of your plan to lose weight fast and start seeing results within two weeks? In my article on how walking can help lose weight, you will find out how many calories you can burn if you add 10,000 steps to your day.

Ways to increase your steps daily include:

High-intensity interval training (HIIT) is an excellent way to quickly lose weight and see results within a short space of time.

HIIT training involves short bursts of intense exercise followed by short recovery periods. For example, it could be 30-40 seconds of hard sprinting followed by 30-40 seconds of light jogging.

According to the Journal of Obesity, high-intensity intermittent exercise or training has been shown to significantly increase aerobic and anaerobic fitness. It also helps the body get rid of excess fat quicker. HIIT exercises can also help to boost cardiac health and reduce the symptoms of type-1 and type-2 diabetes.14

For more information on how you can use interval training to speed up weight loss, please read my article on using interval training to lose fat quicker.

Lifting weights is another proven way to see quick results when wanting to lose extra pounds in a two-week period.

Lifting weights as well as kettlebell workouts help to not only burn calories very quickly but they also build muscle mass which helps to burn even more calories.

A study from Europe reported that heavy-resistance exercise during intense workouts boosts muscle metabolism.15 An increase in your resting metabolic rate also helps to burn calories even when you are resting.

Before starting a program of intense, heavy-resistance exercising, you should speak to a qualified medical professional to get advice.

According to the Centers for Disease Control and Prevention, there are some other ways that can help you lose body weight quickly when used in conjunction with an effective weight-loss plan. Some of these include:31

So far, this article has concentrated on the 3 main principles on how to achieve a goal of losing 20 pounds in two weeks. However, there are some specific weight-loss diets that help to lose a lot of weight in just a few weeks.

The ketogenic diet is a low carb high fat diet that restricts the intake of carbs to help boost the bodys fat-burning potential. Usually, people who start a carb-restrictive diet see rapid weight loss in the first few weeks of dieting. The journal Experimental & Clinical Cardiology reported that a keto diet can help to reduce body mass and body mass index in obese individuals.15

There is one thing that you need to be aware of when dropping carbs from your diet: many of the foods that contain carbs also contain beneficial nutrients and vitamins.

For example, if you eliminate whole grains and brown rice you are going to miss out on nutrients such as b vitamins and magnesium. These are important nutrients for the energy production in your body so you will get tired easily.

The 3-hour diet can help you lose weight quickly without having to cut out many of your favorite foods. According to Dr. Michael Dansinger on WebMD, the 3-hour diet involves eating small portions of food every 3 hours and limiting calories intake to just over 1,400 calories a day. Dr. Dansinger says that visible results are often seen within the first 2 weeks.16

Intermittent fasting, or the 5:2 diet, will help you see quick results to help reach your weight-loss goals quicker. Intermittent fasting involves eating normally for 5 days in the week and restricting calorie intake to 600 calories on 2 non-consecutive days. According to the International Journal of Obesity, far from being a fad diet, intermittent fasting can help achieve weight loss that stays off as long a person sticks to the diet.17

You can find more information about this diet in my article Intermittent Fasting 5:2 Principles, Science and How To.

When searching the internet for ways to lose 20 pounds in 2 weeks, you will come across many unsafe methods to lose weight quickly.

In your diet plan to lose extra weight in under a month, you should avoid skipping meals as a regular habit. For example, a study published in the American Journal of Clinical Nutrition reported that although skipping breakfast can help reduce daily calorie intake, it can increase inflammation in the body.27

Dr. Kathleen Zelman on WebMD reports that breakfast helps improve blood sugar levels and gives the body a needed boost for the day. You also get important vitamins and nutrients from breakfast and reduce the tendency to snack. People who eat breakfast every day are able to lose weight and keep it off.18

Leaving out one or more meals during the day shouldnt be confused with intermittent fasting. Intermittent fasting doesnt involve skipping meals but reducing calorie content on 2 days of the week. However, most 5:2 diets include 3 low-calorie meals during the fasting days that contain a good amount of vitamins and minerals.

If you are trying to lose a lot of pounds in a short space of time, you should stay clear of fad diets. Fad diets may give quick results, but the extra pounds usually pile on very quickly after the diet is finished.

According to the University of Pittsburgh Medical Center, fad diets usually promise quick dieting results with little or no effort. They usually restrict important food groups and can be difficult to maintain. Fad diets can also cause various health complications like kidney stones, high blood pressure, and cardiovascular issues.19

Diet pills will not help you lose 20 pounds in two weeks. Because diet pills and supplements are generally expensive, they could help you lose hundreds of dollars in a month rather than pounds of body fat. According to Dr. Gary Vogin on WebMD, there is only scant evidence that weight-loss pills have a minimal effect when it comes to dieting. Some natural products may help to boost metabolism or stimulate fat burning, but they wont in themselves help you lose weight quickly.20

Starvation diets and extreme fasting are unsafe ways to get rid of a lot of weight in a week or two. According to Dr. Kathleen Zelman on WebMD, even though starvation diets result in rapid weight loss, they can also cause loss of muscle tissue and may even cause your body to burn calories slower. You may find that at the end of the diet, you put on more weight than you lost.21

Doctors from WebMD also say that creams and other so-called weight-loss devices are just as effective and scientifically proven as voodoo spells.22

So, when it comes to losing 20 lbs in 2 weeks, what is the bottom line? Although it is feasible that a person could lose many pounds of body fat in a couple of weeks, these generally involve risky methods of dieting.

To achieve your perfect body weight and maintain good health, you should reduce calorie intake over a period of many weeks, make positive lifestyle changes, and exercise regularly. After all, extra weight was gained over a long period of time.

By making some simple calculations, doctors from the Mayo Clinic advise on the dangers of trying to lose too much weight in a very short space of time.

For example, the Mayo Clinic says that every pound of body fat contains 3,500 calories.23 So, to lose 20 lbs of fat in 14 days, you would have to lose about 1.5 lbs. of fat a day. This means burning on average 5,000 calories more than you consume per day. You also need to be aware that initially you will lose water weight and not just fat.

How many hours per day will you have to work out to lose 20 lbs. in 2 weeks? The Mayo Clinic says that high impact aerobic exercising burns about 650 calories an hour.24 Therefore, you would have to work out for about 7 hours of intense exercise every day for 2 weeks to lose 20 lbs.

The bottom line when it comes to losing a lot of weight rapidly is this: stick to safe and healthy methods of losing weight that will boost your health and help you reach your perfect body weight.

After you have reached your ideal body weight, it is important to maintain that weight. Researchers from the National Heart, Lung, and Blood Institute say that there are 3 ways to maintain a healthy weight. These are:

If you need to lose a lot of weight quickly in the space of a few weeks, you should speak with your doctor first. Your doctor will carry out a medical checkup to check your general health and recommend a diet and exercise regime that will help you achieve your weight-loss goals.

Your doctor will also check for any underlying health conditions that could affect the type of weight-loss plan that will be most effective for you. This includes checking your blood pressure, blood sugar levels, and any signs of joint pain and stiffness.

Also, if you start feeling fatigued, dizzy, lightheaded, or have an increase in watery bowel movements, or generally unwell while on your weight-loss program, you should speak to your doctor.

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How to Lose 20 Pounds In 2 Weeks: Effective Plan to Lose ...

FDA approves Saxenda for the treatment of obesity in adolescents aged 12-17 – PRNewswire

Posted: December 4, 2020 at 11:54 pm

PLAINSBORO, N.J., Dec. 4, 2020 /PRNewswire/ --Novo Nordisk today announced that the U.S. Food and Drug Administration (FDA) approved an updated label for Saxenda(liraglutide) injection 3 mg for use in the treatment of obesity in adolescents (1217 years) with a body weight above 60 kg and an initial body mass index (BMI) corresponding to 30 kg/m2 or greater for adults, as an adjunct to reduced-calorie meals and increased physical activity. Saxenda was approved in 2014 for chronic weight management in adults with a BMI 30 kg/m2, or 27 kg/m2 with at least one weight-related comorbidity, as an adjunct to a reduced calorie meal plan and increased physical activity.1

Over the last 20 years, the global prevalence of children and adolescents with excess weight has doubled from 1 in 10 to 1 in 5.2Research also shows that when both parents have excess weight, 80% of their children will have obesity.3However, current treatment options for this population are limited, highlighting a considerable and growing need for additional treatment strategies.4

"New options to treat adolescents who live with obesity can bring much-needed hope to families and help address this growing epidemic," said Dr. Aaron Kelly, Professor of Pediatrics and co-director of the Center for Pediatric Obesity Medicine at the University of Minnesota. "With up to 90 percent of adolescents with obesity likely to have it as adults and thus at increased risk for developing weight-related complications, it's important to address weight care and offer support early on.3,5I'm encouraged that healthcare providers now have another tool in developing a personalized, complete care plan to help adolescents lose weight and keep it off."

The safety and efficacy of Saxenda as a treatment for adolescents with obesity is supported by data from a phase 3a trial published earlier this year in the New England Journal of Medicine. The 56-week clinical trial investigated the effects of Saxenda compared to placebo for weight management in 251 patients aged 12-17 living with obesity as an adjunct to lifestyle therapy, defined as counselling in healthy nutrition and physical activity for weight loss. In the trial, the primary endpoint was change from baseline in Body Mass Index (BMI) Standard Deviation Score (SDS) at week 56.6

The data demonstrated a significant reduction in BMI-SDS, as well as reductions in BMI, mean body weight, and other weight-related endpoints vs. placebo in adolescents with obesity when using Saxenda as an adjunct to lifestyle therapy. Adverse events seen in an adolescent population were similar to those observed in adults. The most common adverse reactions were gastrointestinal events, including nausea, vomiting and diarrhea.6

"The rise in adolescent obesity is contributing to a public health crisis, and it poses a real challenge for healthcare professionals due to the limited treatment options available," said Mads Krogsgaard Thomsen, executive vice president and chief scientific officer of Novo Nordisk. "We are proud to be able to offer a new treatment option for adolescents with obesity and their families in the US, as the FDA approval marks another significant milestone for Saxenda."

What is Saxenda?

Saxenda (liraglutide) injection 3 mg is an injectable prescription medicine used for adults with excess weight (BMI 27) who also have weight-related medical problems or obesity (BMI 30), and children aged 12-17 years with a body weight above 132 pounds (60 kg) and obesity to help them lose weight and keep the weight off. Saxenda should be used with a reduced calorie diet and increased physical activity.

Important Safety Information

Do not share your Saxenda pen with others even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.

What is the most important information I should know about Saxenda?Serious side effects may happen in people who take Saxenda, including:

Possible thyroid tumors, including cancer. Tell your health care professional if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats and mice, Saxenda and medicines that work like Saxenda caused thyroid tumors, including thyroid cancer. It is not known if Saxenda will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people.

Do not use Saxenda if you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN2).

Who should not use Saxenda?Do not use Saxenda if:

Before taking Saxenda, tell your health care provider about all of your medical conditions, including if you:

Tell your health care provider about all the medicines you take, including prescription, over-the-counter medicines, vitamins, and herbal supplements. Saxenda slows stomach emptying and can affect medicines that need to pass through the stomach quickly. Saxenda may affect the way some medicines work and some other medicines may affect the way Saxenda works. Tell your health care provider if you take diabetes medicines, especially insulin and sulfonylurea medicines.

How should I use Saxenda?

What are the possible side effects of Saxenda?Saxenda may cause serious side effects, including:

The most common side effects of Saxenda in adults include nausea, diarrhea, constipation, vomiting, injection site reaction, low blood sugar (hypoglycemia), headache, tiredness (fatigue), dizziness, stomach pain, and change in enzyme (lipase) levels in your blood. Additional common side effects in children are fever and gastroenteritis.

Please see Prescribing Information and Medication Guide for Saxenda at http://www.novo-pi.com/saxenda.pdf.

About the phase 3 trial (NCT02918279)

The trial investigated the effect of Saxenda (liraglutide 3.0 mg or maximum tolerated dose) compared to placebo for weight management in 251 adolescents (aged 12 to <18 years) living with obesity as an adjunct to lifestyle therapy.6 The trial included a 12-week run-in period of lifestyle therapy, a 56-week treatment period (including dose escalation over 4 to 8 weeks) on Saxenda or placebo and a 26-week follow-up period without Saxenda or placebo.6 All participants received lifestyle therapy beginning with the run-in period and during the 56-week treatment period and 26-week follow-up period.6 The phase 3a trial was a post-marketing requirement of the FDA under the Pediatric Research Equity Act (PREA), which aims to ensure treatments are safe and effective for children and adolescents.7,8

About SaxendaSaxenda (liraglutide) injection 3.0 mg is a once-daily glucagon-like peptide-1 (GLP-1) receptor agonist with 97% similarity to naturally occurring human GLP-1, a hormone that is involved in appetite regulation and food intake.1 Like human GLP-1, Saxenda is believed to work in areas of the brain involved in appetite regulation, including the hypothalamus.1Saxenda for use in adults with obesity was evaluated in the SCALE (Satiety and Clinical Adiposity Liraglutide Evidence) clinical trial program. Since launch in 2015, more than 1.5 million patients have been treated with Saxenda globally.7

Saxenda is already indicated in the US for chronic weight management in adults with a BMI 30 kg/m2, or 27 kg/m2with one or more weight-related comorbidities, as an adjunct to a reduced-calorie meal plan and increased physical activity.1

About obesityObesity is a chronic, progressive and misunderstood disease that requires long-term medical management.9,10 One key misunderstanding is that this is a disease of willpower, when in fact there is underlying biology that prevents people from achieving long-term weight loss.11 Obesity is influenced by a variety of factors, including genetics, appetite signals, behavior and the environment.11 It is a gateway disease and is associated with at least 60 other health conditions.12 The current COVID-19 pandemic has highlighted that obesity also increases the risk for severe illness and hospitalization due to COVID-19.13,14In the United States, more than 42% of adults live with obesity.15

About adolescent obesityAdolescents with obesity are also more likely to develop weight-related diseases, like diabetes and cardiovascular diseases, at a younger age.16Just like other chronic diseases, obesity requires long-term management.9,10 Research shows that when both parents have excess weight, about 80% of their children will have obesity.3 Globally, more than 124 million children and adolescents have obesity.17In the United States, nearly 1 in 5, or about 13.7 million, children and adolescents have obesity.18,19

About Novo Nordisk Novo Nordisk is a global healthcare company that's been making innovative medicines to help people with diabetes lead longer, healthier lives for 95 years. This heritage has given us experience and capabilities that also enable us to help people defeat other serious diseases including obesity, hemophilia and growth disorders. We remain steadfast in our conviction that the formula for lasting success is to stay focused, think long-term and do business in a financially, socially and environmentally responsible way. With U.S. headquarters in New Jersey and production and research facilities in six states, Novo Nordisk employs nearly 6,000 people throughout the country. For more information, visitnovonordisk.us, Facebook, Instagramand Twitter.

References

1US Food and Drug Administration (FDA). Saxenda Prescribing Information. December 2020.

2UNICEF. The state of the world's children 2019. Available at: https://www.unicef.org/media/60806/file/SOWC-2019.pdf. Last accessed: November 2020.

3Lifshitz F. Obesity in Children. J Clin Res Pediatr Endocrinol.2008 Dec; 1(2): 5360

4Cardel M, Jastreboff A, Kelly A. Treatment of Adolescent Obesity in 2020. JAMA. 2019; 322:17071708.

5Gordon-Larsen P, The NS, Adair LS. Longitudinal Trends in Obesity in the United States from Adolescence to the Third Decade of Life. Obesity. 2010; 18 (9): 1801-1804

6Kelly A, Auerbach P, Barrientos-Perez M. A Randomized, Controlled Trial of Liraglutide for Adolescents with Obesity. Available at: https://www.nejm.org/doi/full/10.1056/NEJMoa1916038. NEJM. 2020;DOI: 10.1056/NEJMoa1916038

7Novo Nordisk. Data on File.

8Center for Drug Evaluation and Research. Pediatric Research Equity Act. U.S. Food and Drug Administration. https://www.fda.gov/drugs/development-resources/pediatricresearch-equity-act-prea. Last accessed: November 2020.

9American Medical Association. A.M.A Adopts New Policies on Second Day of Voting at Annual Meeting. Obesity as a Disease. Available at: http://news.cision.com/american-medical-association/r/ama-adopts-new-policies-on-second-day-of-voting-at-annual-meeting,c9430649. Last accessed: November 2020.

10Bray GA, Kim KK, Wilding JPH. World Obesity Federation. Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation. ObesRev. 2017;18(7):715-723. doi:10.1111/obr.12551.

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12Bays HE, McCarthy W, Christensen S, et al. Obesity Algorithm, presented by the Obesity Medicine Association. Available at: https://obesitymedicine.org/obesity-algorithm/. Last Accessed: November 2020.

13Finer N, Garnett SP and Bruun JM. COVID-19 and obesity. Clin Obes. 2020; 10:e12365.

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SOURCE Novo Nordisk

http://www.novonordisk-us.com

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FDA approves Saxenda for the treatment of obesity in adolescents aged 12-17 - PRNewswire

Researchers: high-carb, vegan diet may be the key for weight loss – Atlanta Journal Constitution

Posted: December 4, 2020 at 11:53 pm

These findings are groundbreaking for the 160 million Americans struggling with overweight and obesity, study author Dr. Hana Kahleova, Ph.D., director of clinical research for the Physicians Committee said in a statement. Over the course of years and decades, burning more calories after every meal can make a significant difference in weight management.

Also of note was that the studys diet was 75% carbs, 15% protein, and 10% fat, Business Insider reported. Participants consumed plant-based foods that contain lots of complex carbs. These can increase the thermic effect, which requires the body to use more energy to digest them. They can also boost the number of calories you burn as the meal digests.

The thermic effect, in part, aided participants weight loss. Also of help was the naturally low-calorie, nutrient-dense unprocessed plant carbs.

Plant-based foods are known to be more satiating and less energy-dense, Kahleova said. This clearly shows that a vegan diet can help people lose weight even without an intent to reduce calories.

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Researchers: high-carb, vegan diet may be the key for weight loss - Atlanta Journal Constitution

Teens Benefit From Bariatric Surgery, Regardless of Weight Loss – HealthDay

Posted: December 4, 2020 at 11:53 pm

FRIDAY, Dec. 4, 2020 (HealthDay News) -- Remission of obesity-associated complications (OACs) is not dependent on major sustained weight loss in teens undergoing metabolic and bariatric surgery (MBS), according to a study published online Nov. 24 in Obesity.

S. Christopher Derderian, M.D., from University of Colorado at Aurora, and colleagues used data from the Teen Longitudinal Assessment of Bariatric Surgery to assess the relationship between weight loss and remission of OACs after MBS in adolescents. The analysis included adolescents with severe obesity who underwent MBS between 2007 and 2012 with five years of follow-up data. Lower weight-loss responders (LWLRs) were defined as having <20 percent total body weight loss (TBWL) and higher weight-loss responders (HWLRs) had 20 percent TBWL.

The researchers found that both LWLRs (114 adolescents) and HWLRs (78 adolescents) lost significant weight within the first year following MBS. However, TBWL at five years was 8.6 percent for the LWLRs and 33.8 percent for the HWLRs. At five years, HWLRs were more likely to experience durable remission of composite dyslipidemia. There were no differences in remission rates for all other OACs.

"In looking at the relationship between the extent of weight loss and health benefits obtained, it is clear that patients' health improves regardless of whether or not they sustain high levels of weight loss long-term following surgery," a coauthor said in a statement.

Two authors disclosed financial ties to the pharmaceutical and biopharmaceutical industries.

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Teens Benefit From Bariatric Surgery, Regardless of Weight Loss - HealthDay

Dancing to Lose Weight: Calories Burned, Dance Options, More – Healthline

Posted: December 4, 2020 at 11:52 pm

You might think of dancing as something you just do at the club on Saturday nights. While dancing is a great way to unwind and have fun, it has so many other benefits, too.

In fact, dancing is an excellent way to exercise, burn fat and calories, and lose weight. So, if youre looking to add some new moves to your workout routine, read on to learn how dancing can benefit your weight loss efforts.

Like most forms of aerobic or cardio exercise, dancing has many health benefits, including weight loss.

Besides burning a good number of calories, dancing can also increase your muscle strength. Building lean muscle mass may help you burn fat and tone your muscles.

Some of the health benefits of regular cardio exercise, such as dancing, include:

Dancing also has mental health benefits. Aerobic exercise may help improve your mood and reduce your risk of depression.

Dancing has extra benefits because its often a social activity. Dancing with a partner or in a group can create a sense of community and help you feel more connected to other people.

And just as importantly, its a fun activity. When you enjoy doing something, youre more likely to keep doing it. This is why dancing can be a great way to stay motivated when it comes to exercise for weight loss.

As with most types of exercise, faster, more vigorous forms of dancing will burn more calories than slower dancing. For example, hip hop dancing burns more calories than ballroom dancing.

Below are some examples of how many calories youll likely burn during 30 minutes of dancing if you weigh 150 pounds. If you weigh less, youll likely burn fewer calories, and if you weigh more, youll likely burn more.

The U.S. Department of Health and Human Services recommends that adults get at least 150 minutes of moderate intensity or 75 minutes of high intensity exercise each week for health benefits, including weight loss.

So, if dancing is your main form of exercise, the amount of time you spend doing it depends on how vigorously you dance.

If youre looking for substantial weight loss (5 percent of your body weight or more) experts recommend at least 300 minutes of moderate intensity exercise per week.

There are many different types of dance, all of which offer health benefits and the potential for weight loss.

Many gyms offer dance classes, and there are also plenty of online dance videos you can try to see what form of dance feels right for you.

If you prefer something less structured, you can also just crank up your favorite music in your living room and dance around for 30 minutes or more. If youre moving and getting your heart rate up, youre reaping rewards and burning calories.

If youre interested in specific types of dance classes, here are some popular dance options for exercise and weight loss.

Zumba is a dance fitness program set to Latin and other international music.

It uses interval training, alternating between fast and slow movements. These short bursts of high-intensity exercise help you burn even more calories than just dancing at a consistent speed. And its a full-body workout, so youre able to tone and strengthen many of your muscles.

Zumba has many other health benefits, including:

The choreography in Zumba isnt meant to be formal, so you can join in as long as you keep moving. Many gyms and community centers offer classes that welcome all fitness levels.

Hip hop dancing is a high-intensity, high-impact form of dancing. It includes everything from break dancing to modern dance-like moves. Some gyms may offer hip hop dance classes, but there are also many online videos available to help you become familiar with hip hop choreography.

Benefits of hip hop dancing include:

A lot of hip hop dance involves repetitive motion, much of which is high-impact. These moves can lead to injuries if theyre done incorrectly or if you dont give yourself time to rest in between dance sessions.

Ballet is a form of classical dance that focuses on precise movements and technique. While the slow movements of ballet may not burn as many calories as other types of dance, it can still help improve your health and fitness with:

Many dance studios offer ballet classes for all levels.

If youre interested in ballet movements, you may also want to try barre classes. These classes, which are offered at many specialty studios or gyms, incorporate ballet, yoga, and Pilates into a workout based on small isometric movements.

Pole dancing, also called pole fitness, can be a great form of exercise. It involves moves like holding yourself up on the pole, twisting yourself around, and creating shapes with your body.

In addition to providing cardio exercise, some of the benefits of pole dancing include:

A word of caution: Pole dancing requires a lot of gripping and twisting. You may want to opt for a different form of dance if you have hand, wrist, shoulder, knee, or back injuries. Its also important to train with an instructor to avoid injury.

Ballroom dancing includes partner dances like the waltz, foxtrot, and tango. Even salsa dancing can count as a type of ballroom dancing.

While theres competitive ballroom dancing, its also a great workout for amateurs. Check your local community center or dance centers in your neighborhood to see if they have ballroom dancing classes you can attend.

Ballroom dancing can provide benefits like:

This is a low-impact type of dancing, so its a great way to get aerobic exercise if you have joint issues.

As with any exercise, there are safety precautions to bear in mind to minimize your risk for injury. Following these tips may help you stay safe while dancing:

Dancing is a great way to boost your fitness, lose weight, and gain other health benefits. And its a form of exercise thats often a lot of fun and done in a group setting, which may motivate you to keep at it over the long term.

You can try dancing on your own to your favorite tunes, or you can opt for a more structured format by joining a dance class or group session at your gym or local dance studio. Theres also the option of following along to online videos that focus on dance moves to lose weight.

Whats most important is to find the style and type of dance that you most enjoy. If your goal is to lose weight, aim for more than 150 minutes of moderate intensity dance or 75 minutes of high-intensity dance each week.

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Dancing to Lose Weight: Calories Burned, Dance Options, More - Healthline

Weight loss story: "My breakfast is 2 slices of bread and 4 whole eggs" – Times of India

Posted: December 4, 2020 at 11:52 pm

I workout 5 days a week, with a break on Thursdays and Sundays.

4 days are reserved for upper body workouts and a day for lower body exercise.

I work out hard, but make sure not to strain my back. Basically, do not do any form of complex training, but just the amount that keeps me fit and engaged.

On days I don't feel like working out, or busy, I go on long walks (6km or so).

The secret to my workout is that I solely enjoy it- listen to music that I like, do what I like. That way, it doesn't feel burdensome.

Rest days are important too. I do not overdo, or underdo my trainings.

Low-calorie recipes I swear by: No specific recipes but I am more disciplined about what I eat now.

I stick by my diet, no matter what. I have consciously avoided sugar, sweets and fried stuff for so long and plan to continue to do the same.

Yes, one thing I can say is that I make sure I make each meal a complete satisfaction for me. My theory is that we tend to overeat, not because we are hungry but because we are never satisfied.

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Weight loss story: "My breakfast is 2 slices of bread and 4 whole eggs" - Times of India

Weight Loss: Nutritionist Shares 4 Go-Tips That Beginners Can Bank On – NDTV

Posted: December 4, 2020 at 11:52 pm

Weight loss: Avoid following calorie-restrictive diets and agressive workouts in beginning

If you have just started with your weight loss journey, then this article can be of great help to you. The first few days of any change in life are usually the most difficult ones. You may constantly think of giving up and find it very challenging to adapt to those changes. When you begin with the weight loss journey, both exercising and diet regime may seem difficult to follow. Reducing your calorie intake and trying to move your body after days, weeks and even months of laziness can seem exhausting, especially the first few days.

A lot can be achieved with the help of a few tips and tricks. When it comes to working out, you must always start slow and steady. Give your body the time to adapt to workout and do exercises that challenge you but enable you to do the exercises in the right form.

Speaking of your diet regime, here a few tips that nutritionist Rachel Paul shared on Instagram. These can help you transition to your weight loss diet with the ease.

Also read:Try These Easy Snacking Hacks That Can Keep You Full For Hours

1. Add two cups of vegetables to your meals for volume. Doing so will add more fibre to your meals. Fibre-rich foods can fill you up quickly make you feel full for longer periods of time. They satisfy your hunger while also reducing your appetite.

Add more vegetables to your meals for additional fibre intakePhoto Credit: iStock

2. Add around 150 gms of protein-rich foods like eggs, chicken, lentils or legumes to your lunch and dinner. They will aid muscle build up and will also keep you full. It reduces cravings as well.

3. For those with a sweet tooth, create a dessert plan for the day beforehand. You can have two pieces of dark chocolate, yogurt with honey and cinnamon, a bowl of berries or pomegranate etc. You can also have a small serving of your favourite desserts. Practicing portion control is the key.

Also read:Can Plant-Based Diet Help Boost Metabolism? Here's The Answer

4. Drink as much water as you can. Stick to zero calorie drinks only. Avoid having aerated drinks, fruit juices and even diet soda. All of these drinks are laden with sugar and can disrupt your weight loss regime.

Take less stress and sleep well every day. Both these factors are important for your weight loss regime to work efficiently. Know that the more sustainable your diet and workout plan is, the better it is for you in the long run. Avoid following fad diets and aggressive workouts in the beginning.

Also read:Yoga For Anxiety: Do These 8 Yoga Poses Every Day To Curb Stress, Depression And Anxiety Symptoms

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

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Weight Loss: Nutritionist Shares 4 Go-Tips That Beginners Can Bank On - NDTV

Weight Loss: Try These Easy Snacking Hacks That Can Keep You Full For Hours – NDTV

Posted: December 4, 2020 at 11:52 pm

Healthy snacking can prevent cravings and overeating

How to have snacks that can keep you full for longer? If you have failed to answer this question several times, then this article will be of great help to you. Healthy snacking is an important part of a healthy diet. It can make or break your diet regime, especially if you are trying to lose weight. The snacks that you eat in between meals should ideally be easy-to-cook, filling and nutritious. They should satisfy your in-between meal hunger pangs, but should also not make you skip your main meals.

Making healthy food choices isn't as simple as it sounds. A lot of things need to be taken into consideration, like cooking practice, food combinations, calorie count of meals, their overall taste and nutrition profile of course. In this article, we are going to talk about healthy snacking options and food combinations that are nutritious and can also keep you full for longer.

Also read:Weight Loss: Are Banana Chips A Healthy Snacking Option? Nutritionist Tells

Nutritionist Rachel Paul constantly shares easy-to-prepare and nutritious meals that can keep you full for hours. A few simple hacks are all you need to add that extra quotient of taste and nourishment to your snacks.

Many of us for example, love snacking on fruits. Celebrity nutritionist Rujuta Diwekar says that we must have at least one seasonal fruit every day. Fruits are rich in fibre and several nutrients that help in improving our health and immunity.

So, when you feel hungry in between meals, eating one apple can be a good pick. It will take no cooking time and is also weight loss friendly. But, it will keep you full for only a few minutes. And, you may end up thinking about food even more!

Also read:Trying To Lose Weight? 5 Snacking Mistakes You Need To Avoid

But, if you eat one apple with one or two tbsp of peanut butter, or one string of cheese, or 1/8 or 1/4 cup of nuts, then it can keep you full for hours. "Yes, eating a piece of fruit like an apple is a healthy choice. But many people get hungry and reach for another snack if the fruit is the only food they're eating," writes Paul in the caption of her Insta post.

All of these food combinations can be effective in making your meals more nutritious and filling, thereby reducing your overall calorie intake and aiding weight loss.

Also read:Weight Loss: Is Eating Roti Better Than Eating Rice For Losing Weight?

Try one of these snack combinations today and let us know how it works for you in the comments below.

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

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Weight Loss: Try These Easy Snacking Hacks That Can Keep You Full For Hours - NDTV


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