According to researchers from the from the World Cancer Research Fund and the American Cancer Research Institute, the risk of postmenopausal breast cancer is greatly reduced by being physically active and maintaining a healthy body weight. In this 2019 file photo, execise instructor Jennifer Breedlove leads students in a U-Jam classes.

According to researchers from the from the World Cancer Research Fund and the American Cancer Research Institute, the risk of postmenopausal breast cancer is greatly reduced by being physically active and

According to researchers from the from the World Cancer Research Fund and the American Cancer Research Institute, the risk of postmenopausal breast cancer is greatly reduced by being physically active and maintaining a healthy body weight. In this 2019 file photo, execise instructor Jennifer Breedlove leads students in a U-Jam classes.

According to researchers from the from the World Cancer Research Fund and the American Cancer Research Institute, the risk of postmenopausal breast cancer is greatly reduced by being physically active and

Reduce the risk of breast cancer through a targeted diet and an active lifestyle

Breast cancer is the most commonly-diagnosed cancer among women and the second most common cancer overall with over two million new cases in 2018. While there are many hereditary and genetic factors thought to contribute to developing breast cancer, strong evidence exists the risk of many different types of cancer can be greatly reduced through an active lifestyle, maintaining a healthy body weight and adopting a diet that limits sugar, fast foods, processed foods and favors a plant-based approach, according to researchers from the World Cancer Research Fund and the American Cancer Research Institute.

Our evidence shows that fruit and vegetables, as well as wholegrains and fibre, play a crucial role in protecting us against certain cancers, as well as weight gain, overweight and obesity, Dr Giota Mitrou, World Cancer Research Fund Internationals Director of Research wrote in a 2018 report entitled Diet, Nutrition, Physical Activity and Cancer: A Global Perspective.

The 2018 report detailed evidence that a diet that includes many non-starchy vegetables is believed to decrease the risk of oestrogen-receptor-negative breast cancer. Medical experts now recommend adopting a diet that includes mostly plant-based foods such as whole grains, vegetables, fruits, and beans as a goal toward a healthy lifestyle as plant-based foods are high in the types of fiber, nutrients, and phytochemicals (natural substances) thought to prevent cancer. Researchers say foods rich in fiber, vitamins, and other natural substances called phytochemicals are known to help protect against cancer.

What types of food should be avoided?

Researchers recommend avoiding processed foods high in fat and refined starches such as white bread or pasta, biscuits, cakes and pastries. A diet that includes large amounts of processed foods and fast foods high in fat, starches or sugars also often causes weight gain and obesity, which is known to cause cancer. While most foods undergo some form of processing before consumption, fast food and highly processed foods have generally undergone industrial processing and are often higher in energy and lower in micronutrients. In general, researchers say it is best to avoid potato products such as chips and crisps, products made from white flour such as bread, pasta and pizza, cakes, pastries, biscuits and cookies. Strong evidence also exists that the consumption of either red or processed meat also increases the risk of cancer. Although medical experts dont recommend avoiding red meat completely as it can be a valuable source of protein, iron and other micronutrients, in particular protein, iron, zinc and vitamin B12, but avoiding processed meat that has been transformed through salting, curing, fermentation, smoking or other processes to enhance flavor or improve preservation is advised. Processed meat can include ham, salami, bacon and some sausages such as frankfurters and chorizo. Minced meats such as fresh sausages may sometimes, though not always, count as processed meat. But, a healthy diet doesnt necessarily include meat and those who choose to meat-free diets can adapt their protein selections to include fish or chicken and obtain nutrients through careful food selection.

Related: Online support groups offer hope, support to worldwide sisterhood of breast cancer patients

Medical experts also recommend avoiding sweetened drinks and fruit juices. As for artificially sweetened drinks, researchers say there is no strong evidence in humans to suggest that artificially sweetened drinks, such as diet sodas, are a cause of cancer and the evidence that artificially sweetened drinks help prevent weight gain, overweight and obesity is not consistent. Ultimately, researchers maintain that the available evidence is insufficient to make a recommendation regarding artificially sweetened drinks.

On HoustonChronicle.com: New genetic, genomic tests allow personalized treatment options for breast cancer patients

One of the major problems with sugar sweetened drinks is that they provide energy but do not fill you up. This can promote overconsumption of energy and thus weight gain. This effect is compounded when there are low levels of physical activity, Professor Martin Wiseman, World Cancer Research Fund Internationals Medical and Scientific Adviser wrote in the 2018 report.

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Basic research findings

Exercise and physical activity are key to a healthy lifestyle and researchers recommend a minimum of 150 minutes of physical activity per week. A healthy diet and a healthy body weight are key to reducing the risk of all types of cancer. In terms of a healthy diet, doctors recommend eliminating fast foods, processed foods and sugary drinks as much as possible and advise concentrating on a diet that includes plenty of vegetables whole grain foods.

Link between breast cancer and a healthy heart

The risk of postmenopausal breast cancer is greatly reduced by being physically active and maintaining a healthy body weight. In addition, a sedentary lifestyle and premenopausal obesity not only increase the risk of breast cancer, both are known to contribute significantly to heart disease, according researchers from the American Heart Association (AHA).

Dr. Cindy M. John, a cardiology specialist at he Richmond Medical Center, advises her patients transitioning to a healthier lifestyle to make gradual changes.

You dont have to start by running a marathon every year, John said in an interview Monday (Sept. 21). You can start out by walking 20 minutes five times a week. I also tell my patients that dietary changes dont have start out as extreme changes. For example, instead of having dessert with every meal, start by limiting yourself to dessert once a week.

In addition to healthy lifestyle choices, John says its also crucial to schedule a yearly mammogram and visit a health care provider for regular medical screenings.

Women are often the caregivers in a family, which means we focus on caring for others and often forget to take care of ourselves. But, its just as important to slow down and remember to care for your own health and your own body.

Dr. Cindy M. John is a Board Certified Cardiologist who specializes in preventive medicine and risk factor modification. For appointments, call the OakBend Medical Group Cardiology office at 281-622-4925.

knix@hcnonline.com

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Reduce the risk of breast cancer through a targeted diet and an active lifestyle - Chron

Along with water, exercise and sunlight, food is the fuel of the body and powers everything from our mental and cognitive processes to our muscle movement and strength. Nutrition is vital for all living organisms to source the energy required for growth, body maintenance and reparation.

A healthy diet is essential for avoiding illness, but it also contributes to many other processes integral to our bodys development. Having a balanced intake of nutrients, calories, vitamins and carbohydrates helps all aspects of human development, including the below.

Weight loss and avoiding chronic diseases

In recent years, there has been an exponential rise in diet-related diseases, particularly in Western countries. Being overweight considerably increases the chances of developing heart disease, some cancers, diabetes and problems caused by lower bone density.

In particular, the rise of diabetes has been blamed on a poor diet, leading governments in many western countries to take drastic action and increase taxes on foods proven to be low in nutrients.

Processed foods are also to blame for low consumption of vitamins and minerals while other calorie-rich foods have been attributed to the rise in obesity.

Experts suggest that a diet rich in fiber and lean proteins can help reduce weight loss and remove the need to count calories. In most cases, the dietary diseases that are becoming so prevalent in the west are entirely avoidable. To achieve the best balance, aim to include vegetables and fruits as a regular part of your diet and avoid processed foods.

The link between obesity and cancers

Research has proven a direct correlation between obesity and the risks of developing cancer. Again, a diet rich in fruits and vegetables vastly decreases the chances of problems occurring, particularly in the gastrointestinal tract. Also, vegetables, fruits and fiber each play a significant role in dropping the dangers of rectal and liver cancers. They are also very high in antioxidants that protect from cell mutation and free radicals.

The management of diabetes

For those already suffering from diabetes, a diet low in sugar and salt is essential, as is avoiding highly saturated foods and trans-fats. A healthy diet can help people living with diabetes manage weight, keep blood glucose levels low and maintain blood pressure/cholesterol levels. It can also prevent other complications caused by diabetes, including the loss of sight.

Bone strength and healthy teeth

The primary cause of osteoporosis is a lack of calcium and magnesium, both of which are also essential for healthy teeth and gums.

Calcium deficiency is a common problem but can be easily overcome by eating the right foodstuffs. For example, cauliflower, broccoli, cabbage, tofu, legumes and dairy products are loaded with calcium and magnesium. Also, cereals contain high levels of calcium, while nuts, seeds, grains and green vegetables are a plentiful source of magnesium.

As ever, the key is to mix your diet as much as possible to contain the greatest variety of nutrients.

Eat better, think better, feel happier

There is growing evidence to suggest that eating better also improves our mood and cognitive skills. A diet rich in carbohydrates can improve your brain processing skills.

It has even been found that foods with a high glycemic content can increase depression and fatigue.

There is a wealth of online resources where you can find information to help you improve your diet and source inspiration for a healthier lifestyle. Sites like Myprotein provide inspiration from famous sportspeople and fitness professionals to help you get started down the road towards better living.

Prevention of strokes and other heart-related problems

Heart disease and other blood-related/cardiovascular issues are amongst the most significant health problems in the western world today. It is estimated that around 80% of premature heart disease or strokes could have been prevented by sensible lifestyle changes.

Increased physical activity and improvements to a diet can massively reduce the risks caused by both. Also, it is believed there is a direct link between ingesting trans-fats and coronary heart disease.

Its also suggested that eating vitamin E can help reduce the risk of developing blood clots, so eating foods like almonds, peanuts, hazelnuts or green vegetables (each of which is full of vitamin E), can reduce the chance of developing clots.

An untreated or undetected blood clot can easily pass further through the system to cause a heart attack; therefore, early identification is essential.

Bringing up your children well and teaching them good habits

Most parents realize the things they do will be directly passed down to their children and become habits in later life. Teaching your kids to eat well from an early age (no matter how hard that can sometimes be) is an ideal practice to adhere to. Start young and arm them with a greater understanding and respect for the importance of diet as they grow up.

Sticking to regular mealtimes at home and encouraging your family to eat together can help you monitor and regulate your childrens intake of the right foodstuffs, leading to a healthier diet.

In fact, recent research found that children who regularly ate with their families also went on to eat less sugary, junk foods in later life and also had a higher intake of vegetables. Starting kids along the pathway to a good diet early is an effective way to promote better health in the future.

Improved cognitive and memory processes

Most people are aware that food improves their physical health; however, there is considerable evidence to suggest it also enhances your cognitive abilities. Vitamins C, D and E have been proven to keep minds healthy and also reduce the risks of dementia and other age-related mental problems. To add the best mind-improving ingredients to your diet, look at eating a typical Mediterranean diet filled with omega-3 acids, polyphenols and flavonoids.

A better, healthier gut and digestive process

Our bodies are filled with bacteria, but nowhere more so than the colon. These bacteria are essential for the metabolism and digestive processes and help fight off other dangerous bacteria and viruses.

Eating a diet filled with prebiotics and probiotics help the good bacteria in our gut and digestive system to thrive, promoting better health and an improved digestive tract.

For prebiotics, add vegetables, fruits and greens to your daily mealtimes. For probiotics, yogurt and sauerkraut are a great choice. Fiber also helps improve bowel movements, which can reduce the risk of cancers.

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The Magnificent Benefits of a Healthy Diet - Shared

Country singer Jessie James Decker has major heart eyes for foodand is damn proud of it. "I am such a lover of food," she tells Women's Health. "Everyone around memy friends, my familyknows it; I am a foodie. I think about food when I wake up and I go to bed thinking about if I could have another snack. I just love to eat." Relatable...

The mom of three, Kittenish designer, and newly-minted cookbook author has a lot on her plate, and she's figured out exactly what she needs to fuel all of her projects and stay balanced. "I like to be in shape and feel that energy," Jessie says. "I use food as my fuel."

Just how Jessie eats, though, really depends on the day and she doesn't typically follow a specific diet. "There are some weeks when I'm following more of a strict diet because I have something coming up," she says. "But, you know, for the most part, I'm always enjoying food and I always say 'everything in moderation' on a day-to-day basis."

That said, though she doesn't use the term "intermittent fasting," Jessie's eating habits fall roughly into a 16:8 fasting routine. "I eat what I want to eat within that time frame but don't overdo it," she says. "The timing really is important to me."

Here's what you'll usually find Jessie James Decker eating and enjoying throughout the day.

"When I wake up, I start with some coffee and a little cream and stevia. I drink it all morning long," Jessie tells Women's Health. "I don't like to eat until I'm actually hungry, which is usually later, around 11 a.m."

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When the grumbles kick in, Jessie has her first meal. "I'll have some bread from a local bread company. I get fresh honey wheat bread every week," she says. "That's honestly what we all eat for breakfast: Toast and butter. We have salted butter that we leave out, so it's really nice and mushy when we're spread it on on our bread. We love our toast in the morning."

Jessie's buttered toast is really like a lunch appetizer, because she's ready for her midday meal around 12:30 or 1 p.m.

Exactly what you'll find on her plate varies from day to day. "I've been making these little bowls with tuna on top of salad and a scoop of hummus and a handful of pita chips."

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Or, if she skips her morning toast, Jessie gets that local bread in on her lunch action. "I'll have a tuna sandwich with a handful of barbecue chips, or something similar."

When she needs to whip up something quick, Jessie also keeps a stockpile of frozen meals from Trader Joe's. "They are so good if I don't have time to make myself lunch," she says. "I get the Indian curry or butter chicken and rice meals, and they are so delicious and filling. I have stashes of them in the freezer in the garage. I never want to run out."

Because she gets all the nourishment she needs from her two main meals (lunch and dinner), Jessie isn't much of a snacker. "For me, it's all about eating a bigger lunch," she says. "I don't want to eat anything till dinner and I don't really need a snack."

Unless she and her husband (ya know, Eric Decker) are having a date night, Jessie says her fam always eats a home-cooked dinner and sits down early. "We eat dinner every day between 5 and 5:30 p.m."

Typically, she whips up something from scratch, like pasta, chicken tacos, gumbo, or lasagna. "We get creative" Jessie says. Another family favorite: Grilled steak with a side of grilled corn and tomato salad.

She doesn't restrict herself at dinner, either. "When you're cooking at home and you know what you're putting in your food, I don't think you have to be that strict," she explains. "I don't always think it needs to be grilled chicken over greens. A lot of times I make my homemade pasta so I know what's going in the pasta. It's not that challenging and it's worth it."

Amazon

Just Feed Me: Simply Delicious Recipes from My Heart to Your Plate

You'll find lots of her go-to's in her new cookbook Just Feed Me. "Literally everything in that book is something I have made in my kitchen," Jessie tells WH.

Although she may not be a snacker, Jessie does leave room for some sweet nibbles and sips after dinner. In fact, they're non-negotiable.

"I gotta have dessert one way or the other," she says. "I'll have a handful of chocolate-covered almonds or make chocolate chip cookies. I always want dessert, and the kids always want ice cream, so we get the gallons of ice cream from a local place. I'm not a big ice cream girl, so I don't really join in with them on that one."

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Otherwise, Jessie loves finishing out the day with a little vino. "Or, I'll have a glass of red wine, which kind of takes care of cravings for me."

Usually, this goes down pretty early, so Jessie has plenty of time to digest before bed. "I don't like to eat past 6 p.m. at night," she says.

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Jessie James Decker Basically Follows An Intermittent Fasting DietBut She Doesnt Call It That - Women's Health

Fans might remember Omarion from his early days in B2K, but hes grown up a lot since then, musically and personally. And with that growth comes a new outlook on health and fitness, too.

The singer recently invited Mens Health into his home to break down his gym routineand the one exercise he swears by to keep in shape. The pull-up builds the kind of strength that not everyone can see, he says. If you can do a lot of pull-ups, you dont just appear to be strong. You are strong.

While Omarion admits a lot of his fitness regimen is about keeping himself looking good onstage, its not just about appearances. His main goal for keeping up with intense workouts is to ensure he can keep up the stamina for performances.

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[Working out] definitely helps me manage my energy better, he says about his overall gym philosophy. Thirty minutes onstage for me is literally a full days work. So I make sure I eat right and I make sure I keep my energy high.

As you mature, and someone like me, in my position, that performs and uses their body all the time, it has intensified, he continues. Just doing sit-ups one day, doing weights another day. Its cool, but you really have to have a plan. You have to have a purpose on what it is that you wanna look like.

After a quick workout, its off to the kitchen where Omarion starts assembling all the ingredients for his morning smoothie: frozen pineapple, spinach (his favorite food), ginger, dried cranberries, and honey. While he acknowledges his diet has changed significantly over time, he does laugh about the reason hes so health conscious.

Maintaining a good diet is the key to having great abs, he says. A lot of people wonder where good abs come fromit starts in the kitchen.

When hes not working on maintaining a performance-ready physique by cooking healthy staples like jerk shrimp and smoked salmon, the singer indulges, too. (Soul food and ice cream are his go-tos.) He doesnt sweat it, though, because he gives himself leeway to have a cheat day once in a while. At the end of the day, its all about maintaining a healthy, balanced diet.

"If Im going to get it in with the sugar, if Im going to have some cake," he says, "I always make sure I put in a hard workout after that for sure.

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Omarion Reveals What He Eats in a Day to Stay Shredded - menshealth.com

By: Lifestyle Desk | New Delhi | Updated: September 22, 2020 8:17:26 pmEnsure your diet is full of the required amount of protein. (Source: Getty Images/Thinkstock)

If exercise helps build strength and flexibility, it is ones diet and nutrition intake that builds health and energy. While there are different types of diets that may help one achieve the desired results, many people tend to believe that there are not many adequate sources of protein for vegans. Nutritionist Rashi Chowdhury debunks the myth and lists some commonly found sources of protein for vegans that are also lighter on the gut.

Take a look.

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There are SO many plant based foods that are packed with nutrition and are high in protein but a lot of them might cause issues with the gut so Here are some of my favorite sources of vegan protein that are lighter on the gut! 1- Pistachios Pistachios make for an excellent high-protein snack on the go. You can also use them in your favorite recipe. Theyve got 25 grams of protein per cup 2- Almond butter I LOVE nut butters. Almond butter is a little grittier than peanut butter and contains more fiber, calcium, potassium, and iron. Add a scoop of almond butter on top of your oatmeal, in a smoothie, or slather it on top of a banana or piece of sourdough toast. Contains 7 grams of protein per 2Tbsp serving 3- Organic Edamame These crunchy little guys are fun to eat on their own, straight out of the shell, with a generous sprinkling of coarse salt. Contains 18 grams of protein per 1 cup serving (shelled) please try and go organic here. 4- Pea protein powder Pea protein is a popular vegan protein option. It's easy to digest, and a good source of arginine (an amino acid your body needs to build muscle), and branch chain amino acids (protein compounds that can delay fatigue during exercise). Add some in chocolate or vanilla-flavored powder form to your post-workout smoothie. Contains 14 grams of protein per 2T serving (1 scoop) 5- Spirulina Another richer source of protein than most vegetables! Spirulina is a worthy addition to your morning smoothie or juice. Contains a hefty 57g per 100g, but the average serving is between 1-3g. 6- Chia seeds Chia seeds pack a surprising amount of protein and also high in fiber and are a complete protein. Contains 5g protein per 2T serving 7- Sesame seeds Sesame seeds are rich in lignans that may help burn fat as they cause the body to release more fat-burning liver enzymes. They are also an excellent source of vegan protein. Contains 5g protein per 3T serving Try to mix and match all these vegan protein sources and make sure you eat ATLEAST 20% of your calories from protein Have any more interesting vegan protein sources that you love? Share them with me in the comments below!

A post shared by Rashi Chowdhary (@rashichowdhary) on Jul 17, 2020 at 10:23pm PDT

Pistachios

Pistachios make for an excellent high-protein snack on the go. You can also use them in your favourite recipe. Theyve got 25 grams of protein per cup.

Almond butter

Almond butter contains more fibre, calcium, potassium, and iron than peanut butter. Add a scoop of almond butter to your oatmeal, smoothie, or slather it on top of a banana or piece of sourdough toast. Contains seven grams of protein per two-tablespoon of serving.

ALSO READ | Know how to build immunity with protein amidst coronavirus pandemic

Pea protein powder

Pea protein is a popular vegan protein option. Its easy to digest, and a good source of arginine (an amino acid the body needs to build muscle), and branch chain amino acids (protein compounds that can delay fatigue during exercise). Add some to your post-workout smoothie. Contains 14 grams of protein per two teaspoons of serving or one scoop.

Spirulina

Another rich source of protein, spirulina is a worthy addition to your morning smoothie or juice. Contains a hefty 57g per 100g, but the average serving is between 1-3 grams.

Chia seeds

Chia seeds pack a surprising amount of protein, and are also high in fibre. Contain five grams of protein per two teaspoons of serving.

Sesame seeds

Sesame seeds are rich in lignans that may help burn fat as they cause the body to release more fat-burning liver enzymes. They are also an excellent source of vegan protein. Contain five grams of protein per three teaspoons of serving.

Try to mix and match all these vegan protein sources and make sure you eat at least 20 per cent of your calories from protein, she said.

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Excellent sources of protein for those on a vegan diet - The Indian Express

Have you ever wondered why we yearn for the extremely foods that we attempt to avoid when dieting? Or dream there was a way to switch off the craving?

Researchers from The University of Texas Medical Branch at Galveston have recognized brand-new brain circuits that might serve as a brake on binge consuming and unhealthy food yearning.

In rats who had spent a month eating a low-fat diet plan, researchers successfully hindered the fatty food seeking habits. The findings are currently offered in Behavioral Brain Research.

Craving for foods high in fat this includes many junk foods is an important part of obesity and binge eating, said Jonathan Hommel, assistant professor in the department of pharmacology and toxicology.

When trying to lose weight people often strive to avoid fatty foods, which ironically increases motivation and craving for these foods and can lead to overeating. Even worse, the longer someone abstains from fatty foods, the greater the cravings.

Numerous behavioral studies have demonstrated that rejecting specific foods, like being on a diet, triggers increased yearning and motivation for that food. Nevertheless, the brain systems that cause this type of overeating are not known. To this end, the UTMB researchers sought to find out how the brain drives this possibly damaging behavior.

Utilizing rats that had been placed on a 30-day low-fat diet, the UTMB team trained them to work for fatty treats by pushing a lever. To measure craving and motivation, the scientists kept increasing how many times the rats required to press the lever in order to receive the treat until the rat gave up attempting.

Next, half of the rats underwent a surgical procedure that obstructed the effects of a brain chemical called neuromedin U receptor 2 within an area of the brain that regulates food intake. The other half of the rats did not receive this treatment.

After surgical healing, the scientists found that the rats who had been dealt with did not work nearly as difficult for fatty treats as their unaltered equivalents did.

While our findings are only the first step in a long process from the scientific lab to the doctors office, we are planning to develop new drugs to help curb those cravings, said Hommel. Although it may be years before the drug is ready, our research highlights some important features of food craving that may help you set realistic New Years resolutions.

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Here is why you crave junk food when your on a diet - Drew Reports News

TORONTO, Sept. 22, 2020 (GLOBE NEWSWIRE) -- On September 11, 2020, Health Canada approved Trulicity (dulaglutide) to reduce the risk of non-fatal stroke in adults with type 2 diabetes mellitus who have multiple cardiovascular risk factors or established cardiovascular disease, as an adjunct to diet, exercise, and standard of care therapy. This decision makes Eli Lilly and Companys Trulicity the first and only GLP1 receptor agonist (RA) approved to provide a cardiovascular benefit in people with multiple CV risk factors or with established cardiovascular disease.

The new indication reflects the differentiated patient population of REWIND, the Trulicity cardiovascular outcomes trial. The study consisted primarily of people with multiple cardiovascular risk factors without established cardiovascular disease. REWIND showed a significant risk reduction in MACE-3, a composite endpoint of nonfatal myocardial infarction (heart attack), non-fatal stroke or CV death. Results demonstrated consistent MACE-3 risk reduction with Trulicity across major demographic subgroups. Trulicity's safety profile was consistent with the GLP-1 RA class. The most common adverse events leading to the discontinuation of Trulicity were gastrointestinal events.

REWIND showed that the drug dulaglutide (marketed as Trulicity) reduced major cardiovascular events, including non-fatal stroke, in adults with type 2 diabetes who either had multiple cardiovascular risk factors or established cardiovascular disease, says Dr. Hertzel Gerstein, Professor, and Deputy Director of the Population Health Research Institute at McMaster University and Hamilton Health Sciences, Hamilton, ON. Trulicitys new indication to reduce the risk of non-fatal stroke in these patients will provide physicians with an important tool for type 2 diabetes care.

In addition to its proven glycemic efficacy and easy-to-use device*, Trulicity can now be prescribed to provide cardiovascular benefit to people with type 2 diabetes.

The GLP-1 RA class represents an important advancement in the treatment of type 2 diabetes, says Dr. Doron Sagman, Vice President, R&D and Medical Affairs, Eli Lilly Canada. The combination of Trulicitys proven efficacy along with a new indication for non-fatal stroke represents a significant milestone in diabetes and cardiovascular management.

About the REWIND Study REWIND (Researching cardiovascular Events with a Weekly INcretin in Diabetes) was a multicenter, randomized, double-blind, placebo-controlled trial designed to assess the effect of Trulicity 1.5 mg, a weekly glucagon-like peptide 1 receptor agonist (GLP-1 RA), compared to placebo, both added to standard of care (according to local standard of care guidelines), on cardiovascular (CV) events in adults with type 2 diabetes. The primary CV outcome was the first occurrence of MACE (the composite of CV death or nonfatal myocardial infarction or nonfatal stroke). Secondary outcomes include each component of the primary composite CV outcome, a composite clinical microvascular outcome comprising retinal or renal disease, hospitalization for unstable angina, heart failure requiring hospitalization or an urgent heart failure visit, and all-cause mortality. The 9,901 participants from 24 countries had a mean duration of diabetes of 10.5 years and a median baseline A1C of 7.2 percent. While all participants had CV risk factors, only 31.5 percent of the study participants had established CV disease while 62.8 percent only had multiple CV risk factors Prior (established) cardiovascular disease in REWIND was defined as a history of myocardial infarction, ischemic stroke, unstable angina, revascularization (coronary, carotid, or peripheral), myocardial ischemia by a stress test or cardiac imaging or hospitalization for unstable angina with at least one of the following: ECG changes, myocardial ischemia on imaging, or a need for percutaneous coronary intervention.

The REWIND trial's international scope, high proportion of women, high proportion of people without established cardiovascular disease and inclusion of participants with a lower mean baseline A1C suggest that the findings will be directly relevant to the typical type 2 diabetes patient seen in general practice.

About Diabetes in CanadaApproximately 11 million Canadians live with diabetes or prediabetes. People with diabetes are over three times more likely to be hospitalized with cardiovascular disease and contribute to 30% of strokes and 40% of heart attacks. Diabetes can reduce lifespan by 5 to 15 years and complications are associated with premature death. It is estimated that the all-cause mortality rate among Canadians living with diabetes is twice as high as the all-cause mortality rate for people without diabetes.1

About Lilly DiabetesLilly has been a global leader in diabetes care since 1923, when we introduced the worlds first commercial insulin. Today we are building upon this heritage by working to meet the diverse needs of people with diabetes and people who care for them. Through research, collaboration and quality manufacturing we strive to make life better for people affected by diabetes and related conditions. We work to deliver breakthrough outcomes through innovative solutionsfrom medicines and technologies to support programs and more.

About Lilly CanadaEli Lilly and Company is a global healthcare leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by Colonel Eli Lilly, who was committed to creating high quality medicines that meet peoples needs, and today we remain true to that mission in all our work. Lilly employees work to discover and bring life-changing medicines to people who need them, improve the understanding and management of disease, and contribute to our communities through philanthropy and volunteerism.

Eli Lilly Canada was established in 1938, the result of a research collaboration with scientists at the University of Toronto, which eventually produced the worlds first commercially available insulin. Our work focuses on oncology, diabetes, autoimmunity, neurodegeneration, and pain. To learn more about Lilly Canada, please visit us at http://www.lilly.ca.

For our perspective on issues in healthcare and innovation, follow us on twitter @LillyPadCA and @LillyMedicalCA

Media Contact: Samira RehmanRehman_Samira@lilly.com 647-617-1994

REFERENCES 1 http://www.diabetes.ca, Diabetes in Canada - Backgrounder, pg. 1, February 2020.*In a study, 94% of people said it was easy to use.

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Trulicity (dulaglutide) is now indicated as an adjunct to diet, exercise, and standard of care therapy to reduce the risk of non-fatal stroke in...

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Halloween is one of my favorite times of the year not just because its a great excuse to eat endless Reeses and Kit Kats or watch the best spooky movies, but because dressing up as someone (or something) other than yourself for a night is really fun. But just like everything else in 2020, Halloween this year is going to be different due to the still-ongoing, worldwide pandemic.You can certainly celebrate, but you have to do it in more unique and imaginative ways, Shannon Sovndal, MD, an emergency medical services medical director in Boulder, Colorado and the author ofFragile, tells Refinery29. Id still recommend that you are socially distancing and are outside as much as possible. The biggest mistake you can make this Halloween, according to Dr. Sovndal, is having big parties and gatherings, which are usually a staple of this holiday. Stick to treat-or-treating, and skip the bobbing for apples and shared punch bowl.His suggestion: Host a virtual spooky season rager on Zoom or your favorite video conferencing platform (at this point, we all have one). Or plan a smaller get-together with your quarantine crew or social pod. Just dont expose yourself to new people in the name of Halloween.For those of you taking kids trick-or-treating or going out to gather some candy yourself Dr. Sovndal says that prioritizing a pandemic protective costume is ideal. Wear a costume with a mask, he says. You can get creative with this one. (We just ask that this year you skip the sexy nurse costume.)And, of course, social distancing should still be on your mind when youre out and about. With kids trick-or-treating, the tricky part is you still want to maintain social distancing, he says. Its not because six feet is the magic number, its because youre working with a bell curve to say, Hey Im making it much less likely that were going transmit the disease if I stay 6 feet away.' In a perfect world, Dr. Sovndal says youd be trick-or-treating with a group that youre already exposed to and not interacting with anyone new. He doesnt advise knocking on doors, either. Instead, hes hoping candy-givers put their bowls outside their house, so each group can go and help themselves. Also smart: bringing hand sanitizer along so your kid can clean their hands after digging into a shared bowl like that.If youre unsure about your Halloween plans this year and how to stay safe, the Centers for Disease Control and Prevention recently released a COVID map detailing the risk level in each county across the country. Check out your areas current risk level to learn more about what options you have this year for Halloween. Honestly, at the risk of sounding like a buzzkill, wed all be better off ordering our favorite candy in and watching some scary movies at home this year. (Or, my favorite, a The Simpsons Treehouse of Horror marathon.) Even though it may not be the celebration of your spooky dreams, its better to be safe than sorry especially as we prepare to enter flu season, and the risk of a twindemic looms. Plus, that means I can skip my annual tradition of freezing my kneecaps off in my trendy costume.Like what you see? How about some more R29 goodness, right here?This Halloween, Dress Up As Your Fave 2020 MovieSecret Parties & Zero Hookups: The New Dorm LifeCouples Halloween Costumes, By Relationship Status

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