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Juice detox diet: How to lose half a stone in a week – and keep it off – Express

Posted: August 11, 2020 at 3:42 pm

For three to five days before a juice cleanse it is recommended to start eliminating certain foods like sugar, meat, dairy and alcohol to lower the risk of withdrawal symptoms.

Cutting these food groups out of your diet can also help improve your mood.

It is also advised to increase your fluid intake before the cleanse begins.

You can easily make your own juices at home and should be drinking around three a day, just like you would usually eat meals.

READ MORE:Weight loss: Clever foods to eat to get abs in 2 weeks

Watermelon contains lots of water and is one fruit that has almost no calories in it at all. 100 grams of this juicy fruit contains just 30 calories which will help keep you hydrated.

It is also rich in something called amino acids which can help burn fat when consumed daily in your juice.

Cucumber is one of the best foods that has a high water content and many nutrients.

It is packed with fibre and when juiced, can be refreshing and keep you full for a long time.

It is recommended to stay clear of fruits that are high in sugars as this can actually cause weight gain and high blood sugar.

One great benefit from a juice cleanse is that your body will be getting all of the vitamins and nutrients that it needs.

Healthline says: If you struggle to eat enough fruits and vegetables each day, juicing is a convenient way to get a wide range of important nutrients.

One study showed that a group of overweight men lost 20lbs in just two weeks following a simple juice diet cleanse.

After your juice cleanse it is important to stick to whole foods like legumes and fruits and continue to avoid foods with added sugar or preservatives.

However it isnt recommended to stay on juice diets for a long period of time as they can have many side effects including headaches.

Your body also enters fasting mode for many hours of the day and you can end up putting all the weight back on when returning to normal eating.

Although if you only do a juice diet for around 3 days at a time then you should be able to keep the weight lost off.

You may see weight loss results quickly and are suitable for a quick fix, but long-term, a healthy balanced diet with exercise is recommended to lose weight.

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Juice detox diet: How to lose half a stone in a week - and keep it off - Express

This Is The Worst Thing To Order At Burger King If You Want To Lose WeightIts Over 1,000 Calories! – SheFinds

Posted: August 11, 2020 at 3:42 pm

Burger King is known for its burgers, and the fast food chain is a great spot to stop if you want to indulge in a cheeseburger and fries. However, some of Burger Kings menu items are so bad for you, you might want to avoid them at all costs (even on a cheat day).

One burger in particular packs in the calories, saturated fat, and sodium, which could wreak havoc on your diet and lead to other more serious health problems if you arent careful (or order this on the regular).

With that in mind, keep reading for the worst thing to order at Burger King!

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According to Eat This, Not That!, the one Burger King menu item you should definitely steer clear of is the triple whopper with cheese. This burger has 1,220 calories, 82 g fat, and 1,470 mg sodium--all of which means trouble for your diet and your overall health.

If we compare these stats to your recommended daily intake, it becomes evident that you should never be ordering this burger. According to Healthline, the average woman should be eating 2,000 calories per day while the average man should be eating 2,500 calories per day. (Note, these numbers are to maintain your weight, weight loss would require a calorie deficit.)

That means that this burger would account for over half of your daily calorie intake for women, and a little less than half for men. Either way, it's a lot of calories to consume in one menu item.

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The sodium in this burger is also an issue.Eat This explains, "The American Heart Association recommendsa healthy person should consumeno more than 2,300 milligrams a day of sodium, with hopes of moving toward an ideal limit of no more than 1,500 milligrams per day."

This burger will almost completely meet that 1,500 mg goal.

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As for the 82 grams of fat in this burger (with 32 grams of saturated fat), this can also lead to issues.

According to Mayo Clinic, "[I]f you're following a 2,000-calorie-a-daydiet, your target range for totalfatis 44 to 78 grams aday. Of that, saturatedfat should make up no more than 22 grams."

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Plus, these stats do not even factor in fries or a drink, which will put these numbers even higher, and could potentially lead to more problems.

With this in mind, avoiding this burger is a good idea--especially if you want to order a side of fried. Next time, if you want to indulge in a burger, try to stick to a single patty option and keep an eye on its nutrition facts.

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This Is The Worst Thing To Order At Burger King If You Want To Lose WeightIts Over 1,000 Calories! - SheFinds

Combating Coronavirus Through Reversing Diabetes – PMLiVE

Posted: August 11, 2020 at 3:42 pm

The Diabetes Reversal Company has developed a pioneering programme based on sustainable weight loss, evidence-based lifestyle change and one-to-one clinical support to reduce and reverse the effects of Type 2 diabetes.

The Diabetes Reversal Company has developed a pioneering programme based on weight loss, lifestyle change and one-to-one clinical support to reduce and reverse the effects of Type 2 diabetes, helping deliver the goals in the Governments newly published National Obesity Strategy.

The strategy aspires to help people lose weight to beat coronavirus and protect the NHS, which is particularly important for people with serious underlying health conditions like Type 2 diabetes who are more at risk. Obesity is a public health time bomb in the UK, over one in four (28.1%) of UK adults are obese, which increases the risk of developing Type 2 diabetes by 80%. The figures show that patients with diabetes make up a third of COVID related deaths in England, with Type 2 diabetes patients two times more likely at risk of dying in hospital.

The Diabetes Reversal Company has developed the worlds first GP led weight loss programme to improve and reverse the effects of Type 2 Diabetes and is accelerating its roll out through a pilot programme with London GP practices. This comes at a time when the Health Secretary Matt Hancock has said the NHS could save 100m over 5 years if everyone lost five pounds.

Company founder Dr Rabbani was inspired by the success of the Diabetes Remission Clinical Trial (DiRECT) to devise a lifestyle programme to help people improve their diabetes care. The three-phase programme of weight loss and lifestyle change has been created in collaboration with specialist NHS doctors, dietitians, and nutritionists, with app-based technology for ongoing monitoring.

Phase one involves fast evidence-based weight loss with an 800 calorie a day diet for eight to twelve weeks, using specially formulated total diet replacements in the form of shakes and soups developed by experts at the Diabetes Reversal Company. The second phase reintegrates healthier versions of the patients preferred foods back into their diet with the support of a qualified registered nutritionist. The final phase is based on the Diabetes Reversal Company's Golden 5 Plan focusing on nutrition, movement, sleep, stress management and environmental change to help patients stay healthier for longer.

This innovative work has already delivered proven results. Based on a study of 56 patients over eight to twelve weeks by a qualified nutritionist, patients experienced an average weight loss of 22.6 pounds (10.3 kg) which is over 10% of initial body weight lost and an average BMI decrease of -3.60.

Medical Director and company founder Dr Farhan Rabbani explains the importance on tackling Type 2 diabetes, he said:

The publication of the Governments National Obesity Strategy marks an important step forward in tackling the surge of Type 2 diabetes collectively as a nation. The causal link between the risk and severity of COVID-19 and obesity related conditions like Type 2 diabetes means tackling the two go hand in hand.

Our programme offers clinically led solutions that can deliver long term lasting change to peoples weight and feeling of well-being. We want to move away from traditional reliance on medication and start implementing more evidence-based lifestyle changes to help reduce and reverse the effects of Type 2 diabetes.

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Combating Coronavirus Through Reversing Diabetes - PMLiVE

How to boost your metabolism naturally: seven workout and diet tips from HIIT and better sleep to spicy food – T3 (US)

Posted: August 11, 2020 at 3:42 pm

If youre aiming to boost your metabolism in order to lose weight and keep it off, exercise is definitely one of the best ways to do it, as well explain here. But there are other ways to speed up metabolism and lose weight in the process. Weve collected seven tips to help boost your metabolism and to kick-start your weightloss journey today. Although please note that while these ways to speed up your metabolism are easy to understand, they do require some effort to carry out.

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A slow metabolism can cause a lot of trouble over time but luckily, you don't have to put yourself through the horrors of intermittent fasting or the keto diet in order to boost metabolism although both those diets have been researched thoroughly and shown to aid weight loss, with the right application.

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An improved rate of metabolism can help you keep weight off, and generally turn you into a healthier and leaner individual. As usual, there's no instant fix to be had here, but being fit and having a faster metabolism quickly become a virtuous circle.

If you want to lose weight, you should consider applying some of the tips below to your daily routine. Who knows, they might help you lose belly fat sooner rather than later.

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Why should you try HIIT workouts? For one, it improves metabolism and burns calories long after you finished with your daily HIIT session, making you a fat-torching machine that's on 24/7. The best thing about HIIT workouts is that they can be done anywhere using any sort of equipment: you can do a full body HIIT workout in the park or even follow the ultimate HIIT workout that uses your bodyweight only (and a skipping rope).

You can also have a HIIT sessions on a treadmill, elliptical trainer or rowing machine but even if you haven't got the best home gym setup, you can do HIIT with cheap fitness equipment still available to buy online. Try to do HIIT workouts in the morning: research reveals what is the best time for exercising for weight loss.

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Eating moderately spicy food has lots of benefits and including spicier dishes in your diet can help boost metabolism too. Capsaicin, the chemical that gives chilli peppers their 'hot' taste, is said to help burn more calories and reduce the risk of obesity too. As a 2017 research cites, "epidemiological data revealed that the consumption of foods containing capsaicin was associated with a lower prevalence of obesity" and "dietary red pepper can suppress energy intake and modify macronutrient intake through appetite and satiety regulation".

In another study about capsaicinoids, "it was observed that consumption of capsaicinoids increases energy expenditure by approximately 50 kcal/day, and that this would produce clinically significant levels of weight loss in 1-2 years."

What does this all mean? Spicy food will help regulate your food intake by making you less hungry ("satiety regulation") and it will also help you burn more calories without any exercise. Granted, not many calories, but applying this small change alongside all the other lifestyle tweaks, you can effectively supercharge your metabolism in a sustainable way.

However, don't try to overdo the heat by eating spicy food all the time. As they say, "the dose makes the poison", and eating too much hot food can have an adverse effect on your digestive system.

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According to research cited by Healthline, "proteincauses the largest rise in TEF (thermic effect of food). It increases your metabolic rate by 1530%, compared to 510% for carbs and 03% for fats." As Healthline explains, the "thermic effect of food caused by the extra calories required to digest, absorb and process the nutrients in your meal."

Since digesting protein takes more effort from your body, by eating more of it you will basically work out using your metabolic system (we might be exaggerating here). Protein is also essential for muscle repair and recovery, so if you are actively working out, it is recommended to take between 1.6-2 grams of protein per body kilogram per day.

You should source protein from a variety of food stuff like lean meat, nuts, green veg and eggs. Supplementing protein is also popular among athletes: protein powder shakes are probably the most convenient way to get your protein fix on the go but you can also have protein bars or jerky as well as post workout snack.

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As well as increasing your protein intake and reducing bad fats and carbs in your diet, you should also keep an eye out for a good balance of micronutrients, minerals and vitamins. as in the case protein, these micronutrients should be sourced from vegetables, fish, lean meat etc as the natural sources contain other beneficial substances as well, not just synthesised vitamins found in food supplements.

Probiotics can also help improve metabolism and maintain a healthy gut microbiome, essential for well-functioning digestion. In a research paper published in 2013, the researchers concluded that "Probiotics may restore the composition of the gut microbiome and introduce beneficial functions to gut microbial communities, resulting in amelioration or prevention of gut inflammation and other intestinal or systemic disease phenotypes."

B vitamins have also been said to improve metabolism as they play an essential role in metabolising macronutrients efficiently. Good sources of B vitamins include legumes, eggs, lean meat and bananas

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Everyone likes to sleep in every now and then and we are not suggesting you should wake up super early every day for no reason. Waking up and going to bed roughly at the same time can help your body build a routine which in turn will have a positive effect on your metabolism too. This is especially beneficial for people who otherwise like to hit the snooze button 20 times each morning until they can roll out of bed.

Instead on going cold turkey and wake up much earlier on day one, try moving the wake up time a little bit earlier each day/week until you reached the preferred wake up time. Once you used to the new wake up time, your body will wake up automatically, even without setting an alarm.

It's also beneficial to have food roughly at the same time throughout the day so your metabolic system is at the ready when the food is on its way. Food will be digested more efficiently and quicker too if you stick to an eating schedule. Again, no need to have breakfast 8AM on the dot every morning, but having it around that time will definitely improve metabolism.

Needless to say, eating healthier food stuff can also boost metabolism significantly: fibrous food and plenty of water is key to maintain a healthy gut microbiome.

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This technique may have a very complicated-sounding name Non-Exercise Activity Thermogenesis and a vaguely annoying acronym NEAT but it's actually very simple. NEAT means adjusting how you live your day-to-day life, in order to be more active. You know when exercise experts say, 'Take the stairs, not the lift' and you think, 'Oh yes, good idea,' but then you don't do it? Well NEAT is actually doing things like that.

Like a lot of great ways to get fit, NEAT is perfectly straightforward in principle, but it does require some effort on your part. However the great thing about NEAT for many people is that it specifically does not involve going to the gym or setting aside time for exercise. Although of course, it can also be used as one component of a healthy lifestyle, alongside gym, running, cycling, watching Joe Wicks, etc.

Learn about using NEAT to speed up your metabolism

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Caffeine found in coffee and teas can boost metabolism significantly. Not everyone reacts to caffeine the same way and it is also recommended not to drink too many cups of coffee/caffeinated beverages in a day. Green tea has a lower caffeine content so combining coffee and green tea consumption can have better results.

Drinking more water can also improve metabolism: combine increased water consumption with more fibrous food for the best results.

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How to boost your metabolism naturally: seven workout and diet tips from HIIT and better sleep to spicy food - T3 (US)

Midnight Mania! Daniel Cormier before-and-after video reveals dramatic weight loss ahead of UFC 252 – MMA Mania

Posted: August 11, 2020 at 3:42 pm

Welcome to Midnight Mania!

By all accounts, Daniel Cormier is working extremely hard to regain his Heavyweight title from Stipe Miocic on Saturday night (Aug. 15, 2020) at UFC 252 in Las Vegas, Nevada. The former double-champ has spoken repeatedly about his commitment and intensity to prove himself the better man, and were just a few days away from that contest.

Also by all accounts including his own! Cormier loves to eat. After all, this is the man who earned himself a Carls Jr. sponsorship after complaining that Derrick Lewis stole his Popeyes opportunity. As a result of such questionable food habits, its not uncommon for the 511 Heavyweight to balloon up in weight in the off-season.

As it turns out, such was the case after his loss to Miocic. Cormier posted the following video earlier today, giving a bit of behind-the-scenes info on his fitness.

Quick peek into my journey from April to now, Cormier wrote. I was on that big boy diet, but today I feel ready to go. It was tough but we got back into shape and ready to fight.

Admittedly, we didnt get side-by-side body comparisons, but the difference is clear. Cormier doesnt look healthy in the April flashback, let alone ready to fight for five rounds. Fast-forward to the modern day, and DC looks about as fit as hes ever been at as a Heavyweight.

For absolute top-tier analysis, look to Cormiers team mate Khabib Nurmagomedov, who replied to the post simply, My Fat Friend.

The feud between Yair Rodriguez and Zabit Magomedsharipov continues, but will it ever result in a fight?

I try not to judge tattoos, but ... if this bird is intentional, its hilarious. If not, its unfortunate.

The story behind Beneil Dariushs incredible spinning back fist knockout over Scott Holtzman (watch it!) is awesome.

Derrick Lewis bowel movements have been a recurring story throughout his career, which cannot be said for most athletes.

Happy Shark Week!

Since Michael Chandler just knocked out Benson Henderson (from Southpaw?!?), so perhaps hes a good man to listen to regarding building explosive power.

Punching through a kick works out well or terribly. There is rarely a middle ground.

GIVE UP!

Haraguchi pulled his weight backwards really well, creating a really strong lead hook.

If you dont find this funny or cute or at least vaguely interesting, kindly remove yourself from my column.

Midnight Music: Blood On The Tracks is fantastic as a whole, but Ill admit this track simply popped up while I had music on shuffle.

Sleep well Maniacs! More martial arts madness is always on the way.

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Midnight Mania! Daniel Cormier before-and-after video reveals dramatic weight loss ahead of UFC 252 - MMA Mania

Coconut Products Market Forecast to 2027 – COVID-19 Impact and Global Analysis by Type ; Application ; Distribution Channel ; and Geography -…

Posted: August 11, 2020 at 3:42 pm

New York, Aug. 11, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Coconut Products Market Forecast to 2027 - COVID-19 Impact and Global Analysis by Type ; Application ; Distribution Channel ; and Geography" - https://www.reportlinker.com/p05950843/?utm_source=GNW

Coconuts are highly nutritious as they are high on fibers; vitamins C, E, B1, B3, B5, and B6; and minerals such as sodium, iron, calcium, magnesium, phosphorous, and selenium. Coconut products, i.e., products extracted or derived from coconuts, improve cardiovascular health, promote blood sugar control, aid in weight loss, and boost brain function in Alzheimers disease. Coconut water boosts kidney health, provides a cardio-protective effect, offers rehydrating effect post-exercise, aids in maintaining blood pressure levels, and aids in diabetes management. Additionally, increase in demand for coconut products such as coconut milk, coconut water, and desiccated coconut in the food & beverages industry is one of the major factors driving the market. Food and beverage manufacturers worldwide have invested heavily in research and development to utilize coconut products to enhance the characteristics, taste, or nutritional value of their products. Consumers in developed countries are focused on fitness and health. Active and health-conscious consumers have shifted their preference toward natural alternatives to caffeinated and sugar-based energy drinks. Thus, the demand for coconut water as a natural energy drink is growing rapidly due to its nutritional properties, such as electrolytes and nutrients. Therefore, increasing health awareness, coupled with the advantages of coconut products, is driving the growth of the global coconut products market.

Based on type, global coconut products market is segmented into coconut cream, coconut milk, coconut water, coconut sugar, coconut oil, coconut grated/shredded, coconut desiccated, and others.The coconut oil segment accounted for the major share in 2018 and is expected to continue this supremacy in the coming years.

Coconut oil is a colorless and tasteless product, which is extracted from the kernel of mature coconuts.Based on extraction, it is divided into two types, unrefined and refined or virgin coconut oil.

According to the report published by the National Center for Biotechnology Information (NCBI), coconut oil has been reported to have positive impact on people suffering from Alzheimers disease as it reduces the cognitive deficiencies related to the disorder.Further, a study by the University of Cambridge revealed that coconut oil lessens the risk of acquiring cardiovascular diseases.

Coconut oil increases the high-density lipoproteins (HDL), i.e., good cholesterol, levels, reducing the risk of heart diseases. Moreover, the fatty acids present in coconut oil facilitate burning of harmful body fats, thereby providing energy for brain and body functioning.

Geographically, the global coconut products market is segmented into North America, Europe, Asia Pacific, South America, and Middle East and Africa.The Asia Pacific contributed to the largest share in the global coconut products market in 2018.

This growth is primarily attributed to the wide utilization of coconut products such as coconut cream, coconut milk, coconut water, coconut sugar, coconut oil, and grated/shredded coconut, and desiccated in various regional cuisines and recipes.The growing production of coconut in Southeastern parts of Asia, along with the easy availability of coconuts as a raw material, further propels the growth of the market in Asia Pacific.

The Philippines, Indonesia, India, Thailand, and Malaysia, among others, are the leading producers of coconut and coconut products.Indonesia and the Philippines are the major global exporters of coconut products.

Additionally, Asia Pacific is leading the market in terms of consumption owing to the increasing demand for coconut products as an ingredient in the food & beverages industry. Also, the enhanced distribution systems, with the increasing demand for coconut chips, candy, biscuits, and barfi, among others, is another reason driving the growth of the coconut products market in this region.

COVID-19 outbreak first began in Wuhan (China) during December 2019 and since then it has spread at a fast pace across the world.As of March 2020, China, Italy, Iran, Spain, Republic of Korea, France, Germany, and the US are among the worst affected countries in terms confirmed cases and reported deaths.

According to the latest WHO figures, there are ~14,872,722 confirmed cases and 613,680 deaths globally.The COVID-19 outbreak has been affecting economies and industries in various countries due to lockdowns, travel bans, and business shutdowns.

The global food & beverage industry is one of the major industries that is facing serious disruptions such as supply chain breaks, technology events cancellations, and office shutdowns as a result of this outbreak.The lockdown of various plants and factories in leading regions such as North America, Europe, Asia Pacific, South America and Middle East and Africa is affecting the global supply chains and negatively impacting the manufacturing, delivery schedules, and sales of various goods.

Additionally, the global travel bans imposed by countries in Europe, Asia, and North America are affecting the business collaborations and partnership opportunities. All these factors are anticipated to affect the food & beverage industry, which is negatively impacting the growth of various markets related to this industry in the coming months.

Marico, PepsiCo Inc., The Coca-Cola Company, The Coconut Company, Nexpo Conversion, Danone S.A, Nestle S.A, Sambu Group, Thai Agri Food PLC, and Thai coconut are among the major players in the global coconut products market.

Overall size of the global coconut products market has been derived using primary and secondary sources.The research process begins with exhaustive secondary research using internal and external sources to obtain qualitative and quantitative information related to the global coconut products market.

Also, multiple primary interviews were conducted with industry participants and commentators in order to validate and analyze the data. The participants who take part in such a process include industry expert such as VPs, business development managers, market intelligence managers, national sales managers, and external consultants such as valuation experts, research analysts, and key opinion leaders specializing in the global coconut products market.Read the full report: https://www.reportlinker.com/p05950843/?utm_source=GNW

About ReportlinkerReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

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Coconut Products Market Forecast to 2027 - COVID-19 Impact and Global Analysis by Type ; Application ; Distribution Channel ; and Geography -...

UB study finds testosterone therapy can lead to remission in men with Type 2 diabetes – UB Now: News and views for UB faculty and staff – University…

Posted: August 10, 2020 at 7:48 pm

The findings from a recent study by a UB researcher and others could prove to be a game-changer for men with Type 2 diabetes.

The single-site study, conducted over 11 years in Bremerhaven, Germany, found that testosterone therapy reversed Type 2 diabetes in one-third of the study participants.

The occurrence of this syndrome is common, and with appropriate testosterone replacement, obesity insulin resistance and diabetes may be reversible, says Paresh Dandona, SUNY Distinguished Professor in the Department of Medicine in the Jacobs School of Medicine and Biomedical Sciences at UB. He co-authored the study, titled Remission of type 2 diabetes following long-term treatment with injectable testosterone undecanoate in patients with hypogonadism and type 2 diabetes: 11-year data from a real-world registry study.

The prospective, registry-based study was published in June in the online journal Diabetes, Obesity and Metabolism. Dandona also presented the data at the Annual Mohan Diabetes Foundation Symposium in Chennai, India, on July 25, where he was given the organizations Lifetime Achievement Award.

Type 2 diabetes, also known as Type 2 diabetes mellitus, results from a combination of insulin resistance and insufficient production of insulin, causing high blood sugar. The condition is common, with more than 3 million new cases per year in the United States. Reduced testosterone concentrations are found in 33% of men with Type 2 diabetes.

The discovery of this syndrome of hypogonadism in Type 2 diabetes was made by Dandonas group at UB in 2004. This group then extended the prevalence of this syndrome to include 25% of non-diabetic obese men in 2010. Thus, diabetes and obesity became the main cause of male hypogonadism. The group went on to demonstrate that such patients have additional insulin resistance that reverses with testosterone treatment in 2016.

Testosterone deficiency, which is also called male hypogonadism, contributes to reduced response of insulin to glucose, increased insulin resistance and eventually the onset of Type 2 diabetes.

The objective of the researchers study was to determine if men with Type 2 diabetes who also exhibit hypogonadism, when treated with testosterone in addition to their regular diabetes treatment, would demonstrate improved glycemic control and insulin sensitivity, and possibly eventually experience remission of Type 2 diabetes.

The investigators observed 356 men in a single urology practice clinic over 11 years. All patients received standard diabetes treatment, which included mandatory educational courses and materials. In addition, 178 men with a mean age of 62 years received 1,000 milligrams of subcutaneously injected, slow-release testosterone every 12 weeks after an initial six-week interval. The 178 subjects, mean age 64 years, who opted out of the testosterone therapy served as the control group.

The researchers took numerous measurements, including height, weight, waist circumference, blood pressure, hemoglobin, fasting glucose, HbA1c (the average amount of glucose in blood over a six- or 12-week period), insulin, heart rate, lipids, highly sensitive C-reactive protein and total testosterone, among others. They also assessed quality of life using the Aging Males Symptoms scale. Erectile function was also assessed, using the International Index of Erectile Function. Assessment of these clinical metrics was performed at least twice a year, and data over 11 years were analyzed.

The results showed that the men treated with testosterone had significant progressive and sustained reductions in their body weight, fasting glucose, HbA1c and fasting insulin over the treatment period, the authors wrote. In the control group, fasting glucose, HbA1c and fasting insulin increased.

One-third (34.3%) of men treated with testosterone saw remission of their diabetes; almost half (46.6%) achieved normal glucose regulation with antidiabetic treatment and a vast majority (83.1%) reached their target level of HbA1c.

Patients in the control group saw no remission of diabetes or reduction in glucose or HbA1c levels.

In addition, there were fewer deaths, myocardial infarctions, strokes and diabetic complications in the group treated with testosterone.

The research indicates that long-term treatment with testosterone is potentially a novel additional therapy for men with Type 2 diabetes and hypogonadism, the authors wrote.

The clinical significance of these results is further enhanced by the fact that one-third of men with Type 2 diabetes have hypogonadism. Hence, physicians encounter men with hypogonadism and diabetes very frequently. It is remarkable that while Type 2 diabetes mellitus leads to hypogonadism, treatment of hypogonadism results in remission of diabetes itself, the authors wrote.

Going forward, prospective randomized controlled trials are needed to confirm the data. One such trial is currently in progress.

Dandona is one of the worlds leading experts in the treatment of diabetes and vascular disease. He is also the ex-chief of endocrinology at UB and founder of the Diabetes and Endocrinology Center of Western New York, which is sponsored by the Jacobs School and Kaleida Heath. He sees patients at UBMD Internal Medicine.

Dandonas co-authors on the study include Karim Sultan Haider and Ahmad Haider, urologists in Bremerhaven, Germany; Farid Saad, a consultant to Medical Affairs Andrology at Bayer AG in Berlin; Gheorghe Doros from the Department of Epidemiology and Biostatistics at the Boston University School of Public Health; Markolf Hanefeld from GWT-TU Dresden GmbH and Medizinische Klinik, Universittsklinikum Carl Gustav Carus, in Dresden; Sandeep Dhindsa from the Division of Endocrinology, Diabetes and Metabolism at Saint Louis University; and Abdulmaged Traish from the Department of Urology at the Boston University School of Medicine.

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UB study finds testosterone therapy can lead to remission in men with Type 2 diabetes - UB Now: News and views for UB faculty and staff - University...

Androgen Replacement Therapy Market potential growth, share, demand and analysis of key players research forecasts to 2028 | AbbVie, Inc., Allergan…

Posted: August 10, 2020 at 7:48 pm

This detailed market study covers androgen replacement therapy market growth potentials which can assist the stake holders to understand key trends and prospects in androgen replacement therapy market identifying the growth opportunities and competitive scenarios. The report also focuses on data from different primary and secondary sources, and is analyzed using various tools. It helps to gain insights into the markets growth potential, which can help investors identify scope and opportunities. The analysis also provides details of each segment in the global androgen replacement therapy market

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According to the report, the androgen replacement therapy market report points out national and global business prospects and competitive conditions for androgen replacement therapy. Market size estimation and forecasts were given based on a detailed research methodology tailored to the conditions of the demand for androgen replacement therapy. The androgen replacement therapy market has been segmented by product type (creams/gels, patches, injections, implants, and oral tablets/capsules/gums), by active ingredient type (testosterone, methyl testosterone, testosterone undecanoate, testosterone enanthate, and testosterone cypionate), by distribution channel (hospitals pharmacies, retail pharmacies, and online pharmacies). Historical background for the demand of androgen replacement therapy has been studied according to organic and inorganic innovations in order to provide accurate estimates of the market size. Primary factors influencing the growth of the demand androgen replacement therapy have also been established with potential gravity.

Regional segmentation and analysis to understand growth patterns:

The market has been segmented in major regions to understand the global development and demand patterns of this market.

North America, Europe, and Asia Pacific by region are estimated to dominate the androgen replacement therapy market during the forecast period. These regions have been market leaders for the overall healthcare sector in terms of technological developments and advanced medical treatments. Moreover, the government policies have been favourable for the growth of the healthcare infrastructure in these regions. North America and Europe have an established healthcare infrastructure for product innovations and early adaptations. This is expected to drive the demand for androgen replacement therapy market during the forecast period.

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The US, Germany, France, UK, Canada, and Spain have been some the major markets in the region. Asia Pacific is estimated to register one of highest CAGR for androgen replacement therapy market during the forecast period. This region has witnessed strategic investments by global companies to cater the growing demand in the recent years. China, Japan, India, South Korea, and Australia are amongst some of the key countries for androgen replacement therapy market in the region. Other regions including Middle East, Europe, and Rest of the World (South America and Africa) are estimated to be emerging markets for androgen replacement therapy market during the forecast period.

This report provides:

1) An overview of the global market for androgen replacement therapy market and related technologies.2) Analysis of global market trends, yearly estimates and annual growth rate projections for compounds (CAGRs).

3) Identification of new market opportunities and targeted consumer marketing strategies for global androgen replacement therapy market .4) Analysis of R&D and demand for new technologies and new applications5) Extensive company profiles of key players in industry.

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The researchers have studied the market in depth and have developed important segments such as product type, application and region. Each and every segment and its sub-segments are analyzed based on their market share, growth prospects and CAGR. Each market segment offers in-depth, both qualitative and quantitative information on market outlook.

With an emphasis on strategies there have been several primary developments done by major companies such as AbbVie, Inc., Allergan Plc, Bayer AG, Endo Pharmaceuticals, Inc., Eli Lilly and Company, Kyowa Kirin International Plc, Mylan N.V., Novartis International AG, Pfizer, Inc., Clarus Therapeutics, Ferring Holding SA, Perrigo Company Plc, Acerus Pharmaceuticals Corporation.

Market Segmentation:

By Product Type:o Creams/Gelso Patcheso Injectionso Implantso Oral Tablets/Capsules/Gums.

By Active Ingredient Type:o Hospitals Pharmacieso Retail Pharmacieso Online Pharmacies

By Distribution Channel:o Testosteroneo Methyl Testosteroneo Testosterone Undecanoateo Testosterone Enanthateo Testosterone Cypionate

By Region:

North America Androgen Replacement Therapy Marketo North America, by CountryUSCanadaMexicoo North America, by Product Typeo North America, by Modalityo North America, by Distribution Channel

Europe Androgen Replacement Therapy Marketo Europe, by CountryGermanyRussiaUKFranceItalySpainThe NetherlandsRest of Europeo Europe, by Product Typeo Europe, by Modalityo Europe, by Distribution Channel

Asia Pacific Androgen Replacement Therapy Marketo Asia Pacific, by CountryChinaIndiaJapanSouth KoreaAustraliaIndonesiaRest of Asia Pacifico Asia Pacific, by Product Typeo Asia Pacific, by Modalityo Asia Pacific, by Distribution Channel

Middle East & Africa Androgen Replacement Therapy Marketo Middle East & Africa, by CountryUAESaudi ArabiaQatarSouth AfricaRest of Middle East & Africao Middle East & Africa, by Product Typeo Middle East & Africa, by Modalityo Middle East & Africa, by Distribution Channel

South America Androgen Replacement Therapy Marketo South America, by CountryBrazilArgentinaColombiaRest of South Americao South America, by Product Typeo South America, by Modalityo South America, by Distribution Channel

Reasons to Buy This Report:

o Provides niche insights for decision about every possible segment helping in strategic decision making process.o Market size estimation of the androgen replacement therapy market on a regional and global basis.o A unique research design for market size estimation and forecast.o Identification of major companies operating in the market with related developmentso Exhaustive scope to cover all the possible segments helping every stakeholder in the androgen replacement therapy

Customization:

This study is customized to meet your specific requirements:

o By Segmento By Sub-segmento By Region/Countryo Product Specific Competitive Analysis

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Androgen Replacement Therapy Market potential growth, share, demand and analysis of key players research forecasts to 2028 | AbbVie, Inc., Allergan...

Testosterone Replacement Therapy Market Demand Forecast Analysis by Emerging Growth Factors and Revenue – Owned

Posted: August 10, 2020 at 7:48 pm

Transparency Market Research (TMR) has published a new report titled, Testosterone Replacement Therapy Market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 20192027. According to the report, the globalTestosterone Replacement Therapy marketwas valued at US$ 1,613.7 Mn in 2018 and is projected to expand at a CAGR of 4.4% from 2019 to 2027.

Overview

Growing Awareness about Testosterone Replacement Therapy to Drive Market

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North America to Dominate Global Market

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Competitive Landscape

The global Testosterone Replacement Therapy market has been segmented as follows:

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Testosterone Replacement Therapy Market Demand Forecast Analysis by Emerging Growth Factors and Revenue - Owned

Does vitamin D keep you safe from Covid-19 and should you be taking supplements? – Chronicle Live

Posted: August 10, 2020 at 7:46 pm

How can you keep yourself safe from Covid-19?

This is the question tens of millions around the world are asking themselves every day during the pandemic.

The most important answer is to follow the social-distancing guidelines - but there are dozens of more complex factors being urgently investigated by scientists.

A range of characteristics are under interrogation to see how they might interact with the coronavirus, including diet, smoking and ethnicity.

The role of vitamin D, sometimes called the sunshine vitamin' is one of them and has become an area of intense interest for researchers trying to understand why certain people are disproportionately affected by the disease.

But what is it, why is it important and do we all need to be taking supplements to keep us safe this winter?

Here's everything we know about it so far.

Vitamin D is a nutrient which regulates how much calcium and phosphate we have in the body, which are needed to keep bones, teeth and muscles healthy.

There are two natural ways to get vitamin D: through sunlight in the summer months coming into contact with your skin or through your diet.

It is relatively uncommon in the food we eat but can be found in oily fish, red meat, liver, egg yolk and fortified foods (like fat spread and breakfast cereals), according to the NHS.

The UK has one of the highest rates of vitamin D deficiency in Europe, partly due to out gloomy winter weather.

Before Covid-19 existed, the Government was already recommending the use of supplements in the winter months (especially for people who spend a lot of time indoors, including the elderly, and people with darker skin).

Some research indicates vitamin D plays an important role in regulating the immune system, although the exact nature of this isn't firmly established.

The immune system is crucial here, not just because of its role in fighting off the disease initially, but also because there is growing evidence that an auto-immune overreaction which harms the body called a cytokine storm could be behind some Covid-19 related deaths (especially where there are no obvious underlying health conditions).

And because sunshine is a major source of the nutrient, specific attention was given to it due to increased time spent indoors during lockdown.

Mortality rates have also been higher in groups known to have deficiency, including older people in care homes and people from a BAME background (darker skin is known to be less effective at absorbing vitamin D).

In short, the jury is out - but there has been a clear shift in recent weeks towards putting a greater emphasis on the role of vitamin D in public health messaging.

Several studies in recent months have been trying to establish a link between rates of Covid-19 infection or mortality and with levels of vitamin D in a population.

One interesting study compared mortality rates from Covid-19 with latitude of countries to see if there are higher death rates in countries which don't get much sunlight in the winter.

It found that there was a possible connection, although there are some notable outliers (for example, high death rates in sunny Spain and Italy and low death rates in Nordic countries).

The study concluded that, while a link between vitamin D and Covid-19 isn't certain yet, there is good evidence it regulates the immune system and that more research is "urgently needed".

The Royal Society has acknowledged the latitude link and recommended the Government ramp up messaging about vitamin D supplement. Experts acknowledged the link is not conclusive but said "several lines of evidence suggest a possible role".

The National Institute for Healthcare Excellence (NICE) have released a report saying the link is inconclusive but the Government should continue to promote supplement taking.

Adrian Martineau, of the Institute of Population Health Sciences at Queen Mary University of London, was quoted by The Lancet as saying: At best vitamin D deficiency will only be one of many factors involved in determining outcome of COVID-19, but it's a problem that could be corrected safely and cheaply; there is no downside to speak of, and good reason to think there might be a benefit.

The NHS reissued its advice on taking vitamin D supplements in April to reflect circumstances of the lockdown: "Consider taking 10 micrograms of vitamin D a day to keep your bones and muscles healthy.

"This is because you may not be getting enough vitamin D from sunlight if youre indoors most of the day.

"There have been some news reports about vitamin D reducing the risk of coronavirus. However, there is currently not enough evidence to support this. Do not buy more vitamin D than you need."

There is more specific advice, including for children, here.

There is some compelling evidence that vitamin D and higher mortality rates from Covid-19 are linked but it is a long way off being conclusively established.

The Government and NHS were already advising us to take supplements during the winter - 10mg for most people and never more than 100mg - especially for people at higher risk of deficiency.

We should all follow that advice, especially as the summer months draw to a close.

We'll may have a better grasp of the link with Covid-19 soon but we know one thing for certain: Social distancing is still the best way to stay safe.

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Does vitamin D keep you safe from Covid-19 and should you be taking supplements? - Chronicle Live


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