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Alzheimers Disease Affects More Women Than Menand Some Experts Think The Reason Why Lies in the Gut – Well+Good

Posted: June 25, 2020 at 10:53 pm

Alzheimers diseasea progressive mental deterioration that can occur in middle or old ageis what experts call a complex medical condition. It isnt caused by one singular factor, like a caffeine-induced headache or a broken bone caused by an injury. Complex diseases involve multiple genes and environmental factors. In other words, its complicatedvery complicated, which has long hindered our understanding of the disease.

Further complicating matters is the fact that Alzheimers disease affects upwards of 5 million Americanstwo-thirds of whom are women, per the Womens Alzheimers Movement (WAM). While the disproportionate effect of Alzheimers on women has long been known, scientists and doctors are only relatively recently starting to understand why. Answering the why just may change the course of action in terms of both prevention and treatment.

But what do you focus on when it comes to a disease that has myriad risk factors, including genes, hormones, diet, stress, and environmental factors? For some of the leading experts in Alzheimers research, theyre choosing to focus on the gut.

Alzheimers is a deterioration of the brain, so it can be a little confusing to know why exactly the gut is taking center stage. As with seemingly everything else in health these days, it all comes down to the microbiome.

The microbiome is all the bacteria, fungi, and viruses that live in the gut, says Laura Cox, PhD, an instructor at the Ann Romney Center for Neurologic Diseases at Brigham and Womens Hospital and Harvard Medical School. (She received a grant from WAM in 2020 to fund her research.) Its important to have a high population of certain good bacteria strains and fungi in the gut. The good guys are linked to a variety of health benefits, including thriving brain health, while bad bacteria is linked to (amongst other health problems) deteriorating brain health.

Heres why: What happens is that as we age, everything starts to break down. This is normal and natural, and we try to fight it, Dr. Cox says. This is called inflamm-aging, aka inflammation due to age. The gut barrier (which lines the inside of the gut and prevents harmful substances from being absorbed by the body) and the blood-brain barrier (the protective blood vessels surrounding the central nervous system) are included in this gradual systemic breakdown.

This is problematic for two reasons. One, these barriers become less able to block harmful microbes, pathogens, and other substances from circulating through your system. Second, since inflamm-aging impairs the immune system, the body is less able to kill harmful bacteria and pathogens that escape through the gut. So you could have increased exposure to microbial products that are getting from the gut to the brain, Dr. Cox says. Both of these factors can lead to further bodily inflammationand experts believe that inflammation in the brain lays the groundwork for Alzheimers.Given that the majority of your immune function happens in the gutand that your microbiome supports said immune function as well as the integrity of the gut barrierand you can see why researchers are interested in the relationship between the brain and the gut.

Hemraj Dodiya, PhD has been studying the differences between the microbiome-brain connection as it relates to Alzheimers in women versus men for three years at the University of Chicago. He says that sex hormones and physiology in men and women affect the gut bacteria in the microbiome. The main question Dr. Dodiya and his team are working to answer is what bacteria strains in the gut are linked to amyloid deposits, which are buildups of plaque in the brain increasing the risk of Alzheimersand what strains are linked to reducing these deposits.

One study showed that a cocktail of five different antibiotics worked to reduce amyloid deposits in male mice, but not female mice. We can attribute this to the male mice having a protective bacteria in the gut, while the female mice could potentially have a pro-inflammatory type of bacteria in the gut, Dr. Dodiya says. Male and female mice have completely different reactions to antibiotic treatment that allows colonization or growth of certain bacterial species.

Dr. Dodiya says hes now exploring in several different experiments exploring how reproductive hormones interact with the bacteria in the gut and immune cells, in order to see if that explains the above-mentioned sex differences in the guts of mice. [This communication] could then modulate what bacteria live and what bacteria die, he says. One experiment involves castrating male mice and studying how that changes their microbiomes. In another experiment, testosterone supplements are given to female mice to see how that affects their microbiome. One experiment that Im working on is taking good bacteria from male [mice] and giving it to female mice, Dr. Dodiya says.

Dr. Cox has seen promise with female mice going a different route: reducing carbohydrate intake. What was surprising about the study was that reducing carbs [to less than 30 percent of the overall diet] showed to be effective in reducing amyloid deposits in female mice, but not male mice, Dr. Cox says. Another surprise from the study is that the microbiomes of the female mice aged faster than the males (meaning they started to break down sooner). But restricting carbs helped slow that aging process in the female mice, she says.

All these mice experiments have some big takeaways for the future of Alzheimers prevention and treatment, particularly in women. Dr. Dodiya says that he could see it leading to the development of probiotic supplements formulated to prevent Alzheimers, with different stains for women than men. This is an outcome Dr. Cox says she could see too; designer probiotics that work as different drug therapies for men and women. But she emphasizes that more research needs to be done to pinpoint exactly what bacteria strains can cause Alzheimers, as well as which strains could play a role in prevention. Were still several years off from that knowledge.

Another possible treatment method could lie in fecal transplants, pending how the experiment taking good bacteria from male mice and giving it to female mice turns out. (Yes, the idea of it may take some getting used to, but fecal transplants are already showing success when it comes to improving someones microbiome.)

In terms of the carb reduction study, thats something Dr. Cox says women can consider putting into practice now with doctor supervision, though she emphasizes that the takeaway shouldnt be confused with reducing calories to an unhealthy level. After all, your brain needs sufficient vitamins and nutrients to function properlyand carbohydrates are the brains preferred source of fuel. Malnutrition in the elderly is already a problem, so its important to be mindful of this, she says. Its more about eating fewer carbs and enough other beneficial macronutrients like protein, fat, and fiber.

Whats clear is that while all of this research is promising, more needs to be doneespecially on humans, not just mice. But whats encouraging is that researchers are really honing in on the differences between what causes Alzheimers in men versus women, something that was long ignored. And addressing those differences lies a prevention plan that could be affective for everyone.

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Alzheimers Disease Affects More Women Than Menand Some Experts Think The Reason Why Lies in the Gut - Well+Good

COVID – 19: Is There Healthily Thereafter? – Patch.com

Posted: June 25, 2020 at 10:53 pm

As SARS-CoV-2 virus spread throughout the globe and caused the largest amount of COVID-19 cases and deaths in the US, there is hardly a person on this planet who is unaware of the coronavirus.

While ending the lockdowns across the country with safety precautions and making sure hospitals are not overwhelmed, public officials and physicians alike are waiting to see the way coronavirus behaves in the next several months. Will we see a substantial increase in the cases during the summer or will the hot weather keep it at bay? Rising number of cases in Florida and Arizona despite the heat is certainly concerning and our eyes are on them, waiting to see how the situation progresses. Will SARS-CoV-2 return in the fall and winter months causing another spike in cases in New York and New Jersey?

With each day we learn more about the virus and about the ways to treat it.

Doctors gain experience, share knowledge and are now better prepared to treat the sick. There are many treatment protocols used in various countries, different hospitals, medical wards and intensive care units, although uniformed guidelines are still lacking.

The controversy about the Hydroxychloroquine, the drug to treat malaria and rheumatoid arthritis, continues, with some randomized studies about it withdrawn from the most respected medical journals (NEJM and Lancet), but some others still ongoing. New medication Remdesivir recently received emergency use authorization by FDA. Old medicine Dexamethasone (a familiar glucocorticoid) was recently shown in a UK-based trial to improve survival of hospitalized patients on mechanical ventilation by 30% and of hospitalized patients on oxygen by 20%. Some other off-label medications include Ivermectin, colchicine, antibiotics, antiretrovirals, immunoglobulins, convalescent plasma, and Toclizumab (an IL-6 inhibitor which can prevent the cytokine storm).

We discovered that COVID-19 not only affects the immune system, gastrointestinal and respiratory systems, causing bronchitis, pneumonia, and acute respiratory distress syndrome. It also produces hematological complications causing widespread blood clotting. Specifically, COVID-19 has been shown to cause dysfunction in the inner lining of the arteries (endothelium) and the treatment for blood clots (anti-coagulants) is now used to avoid life threatening complications. An important observation, shared by many physicians across several states, has been that in the newly diagnosed cases of the last several weeks, including June of 2020, we see that patients are not as sick, outcomes are better even with hospitalized patients. We also observe better survival rates. It is too early to say if the reason behind it is mutation and weakening of the virus or if there are other factors contributing to improved outcomes. Infection fatality rate (defined as deaths among all diagnosed, undiagnosed and asymptomatic individuals) seems to be between 0.4-1% according to various epidemiological reports. While it is still higher than influenza which carries about 0.1% death rate, the risk of dying from COVID-19 turns out to be much less than initially feared and estimated in March-April of 2020 when the case mortality rate (defined as deaths among those who were diagnosed with disease) was thought to be up to 5%.

Traditional medicine still does not recommend much for mild to moderate disease, as the majority of people will recover from COVID-19 without intervention. However, learning that there are delayed complications, such as prolonged fatigue, lingering cough, blood clots, and rashes, maybe we should be paying more attention even to the seemingly mild and moderate cases, those which do not require hospitalization. It is not uncommon for the patients to have persistently elevated levels of inflammatory and blood clotting markers and develop depressed mood and anxiety. The latter two can happen with any serious medical illness. Some physicians treat mild and moderate cases with off-label medications and supplements based on experiences with MERS and SARS and anecdotal reports from colleagues all over the world. We have observed a lot of positive progress with the use of off-label medications and natural supplements based on collective experience of many physicians, but without a gold standard randomized control trial it is impossible to definitely state whether these patients would have recovered by themselves without any intervention.

It is currently believed based on epidemiological models, that during the pandemic, the novel virus will continue to infect the world's population until about 70-80% of people are infected and herd immunity is achieved. Short of a rapidly produced vaccine or natural weakening of the SARS-CoV-2, it will mean that most of us will be exposed to the coronavirus at some point, regardless of the length of the quarantine. If and when that happens, one of two things will take place. If our immune system is stronger than the virus, we will be able to inactivate it with our own immune cells. Those people may become infected but be asymptomatic or have very mild symptoms. If our immune system is weaker than the virus's ability to enter our cells and replicate can overwhelm our defenses, leaving a person very sick, possibly progressing to life threatening complications. Research on hospitalized patients with COVID-19 revealed that older individuals, people with pre-existing conditions, such as hypertension, obesity, diabetes and cancer develop more severe disease and are at higher risk of death.

In the absence of a vaccine or a proven cure, strengthening one's immune system and practicing social distancing may be the only preventative strategies we have while the pandemic runs its course. Much like people have been preparing and stocking up on groceries and household supplies, we should be taking care of our immune system and prepare now. Our immune system is very complex and the process of becoming the healthiest version of yourself is not overnight, but simple steps can be employed right away to start the journey.

Getting adequate sleep, about 7-8 hours, will improve the body's response to illness. Decreased sleep duration has been linked to increased inflammation. Even mild sleep deprivation can cause elevation in pro-inflammatory markers, such as c-reactive protein, and cause immunodeficiency, thus decreasing the response of our body to several antigens. For example, only six days of restricted sleep tends to decrease immunity against influenza vaccination and enhances susceptibility to the common cold.Getting adequate sleep improves not only our cellular function and immunity but also helps to eliminate toxins from our body.

Eating a diet rich in fruits, vegetables, lean proteins, which constitute a healthy antiinflammatory diet, provides minerals, nutrients, and vitamins for proper cellular function. Studies show that only one meal full of refined sugars and trans-fats produces abnormal insulin response which, in turn, decreases function of macrophages. Targeted supplementation with vitamins and minerals which may specifically improve immunity can also be helpful. Zinc helps decrease viral replication, Vitamin D helps immunity, Vitamin C works as an antiviral and an antioxidant, Vitamin A helps the cells in the respiratory tree, flavonoid quercetin is also a potent antioxidant. Prior studies have shown the efficacy of Zinc in reducing colds caused by other coronaviruses. Antioxidant, antimicrobial and antiviral roles of Vitamin C are also well documented. Many of these supplements can be taken orally and some can be given intravenously, such as Vitamin C, which has decades of research showing its safety and efficacy. Higher doses of vitamin C have been given by doctors in Wuhan when the outbreak started and some hospitals and clinics in the US have also followed suit. Longer term preparedness would include seeing your doctor for a check up, getting routine blood work done, including immune markers, microbiome markers and micronutrients in order to target supplementation for deficiencies appropriately and to monitor optimal levels for the future.

Keeping mental health a priority is another important aspect of our daily activities during pandemic. With pandemic and economic uncertainties, physicians are seeing more complaints of anxiety and depression. In addition, breaking daily news around the country and the world creates negative emotions that impact hormones, releasing adrenaline and cortisol which can impair immune cells. Taking control of the information overload and limiting TV and social media to a daily minimum of 20-30 minutes can help balance our thoughts, increase parasympathetic nervous system response which will, in turn, improve mood, sleep and health.

Breaking the tradition of making health resolutions for the New Year's, we should take a closer look at what we can do this summer to help nurture our emotional resilience and strengthen our immune system. As we tame our anxieties, safely ending the lockdowns, these health optimizing strategies, whether holistic or medically supervised, can prove to be lifesaving. Going outside for a walk, normalizing sleep hygiene, enjoying the sun for a natural dose of Vitamin D, practicing mindfulness, swimming in the ocean or going for a hike for a minimum of 150 minutes per week are tools in our wellness toolbox which can allow us to ride the wave of COVID-19.

This post is an advertorial piece contributed by a Patch Community Partner, a local sponsor. The views expressed in this post are the author's own.

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COVID - 19: Is There Healthily Thereafter? - Patch.com

Im A Physician Who Had Breast Cancer, And Here Are The Knowledge-Based Decisions I Made For Myself – Yahoo Lifestyle

Posted: June 25, 2020 at 10:53 pm

So, 2020 has really been a shit year.

It has been for nearly everyone, of course, and when the stuff stops hitting the fan, we all need to take a collective breath, pat ourselves on the back, and celebrate.

I had a busy year planned for 2020: Im a gynecologic surgeon seeing patients and trying to build a badly needed menopause clinic in a local hospital here in Seattle. Im editing a book, and consulting and providing telemedicine care for women in menopause as Chief Medical Officer at Gennev.

Then in January, I got a diagnosis of breast cancer, and suddenly I was making new plans. Somehow I had to carve out five weeks from this life to recover from a double mastectomy, then more time later for recovery from reconstruction. I managed it, barely, to have my first surgery in March.

I thought I had it pretty much under control. My patients were scheduled with other physicians, meetings were on hold, a bunch of work up-front meant I could relax and heal. In February, I went on a vacation to Mexico, where I spent a lot of time crying on beaches and into margaritas with friends. It helped. I came back ready to move forward.

And then COVID-19 hit, and it hit right here at home: epicenter, Seattle.

Suddenly the chaos and noise of my own life have expanded to a global level, and all of us in health care are scrambling to find answers, help others stay calm and safe, keep ourselves as safe as possible on the front lines, and meanwhile Im trying desperately to ignore the little voice inside thats saying, What about me?

As a physician and surgeon, I know what cancer looks like. I have an idea how it progresses and how bad treatment can be. I wanted to get on with it, have the surgery and whatever treatment so I could recover and get back to my life. But with my first surgery scheduled for mid-March, now it looked like those carefully extracted five weeks werent mine anymore.

Oh, and did I mention, suddenly my kids were home all the time? Theyre pretty much grown, so I have it easier than many, but the advanced clusterf*ck of trying to home school an attention-deficit high schooler while sympathizing with my college kid who was missing out on some pretty important stuff in her education and future career (shes a dancer) deflated any zen I managed to scrape together in a hurry.

Story continues

This is a tough time for teens and young adults who rely on their social structures more than ever, and suddenly mine were stuck with a sick mom and Zoom.

Despite being a pretty practical person, I havent always approached my health practically. It wasnt until I was diagnosed as pre-diabetic at 42 that I finally started taking some things seriously. Perimenopause had added some belly fat and bumped up my bad cholesterol, so I at last started exercising regularly and taking medication, since eating better wasnt enough anymore.

However, as someone with a family history of cancers, Im a huge advocate of screening and started annual mammograms at 40.

Now thats irony, Alanis.

As with most women in their 40s, the mammograms showed that I had dense breasts, but nothing particularly concerning.

Then Gennev started working with MiraKind, an organization researching the connection between a gene defect called the KRAS variant and a greater likelihood of developing certain cancers. I got tested, and sure enough, I was a carrier. Knowing being KRAS positive could mean I was more susceptible to breast cancer, I added an MRI to my usual mammogram (remember, dense breasts).

Two days later, they called me and said, So, there are a couple of masses on your MRI. A couple of biopsies revealed invasive ductal carcinoma. More testing, more biopsies, more black and blue boobs.

Now I had a decision to make: I could get bilateral lumpectomies and sign up for a life of going in every six months and probably having to get biopsies every six months. Eventually theyd find something, and Id be right back here again. Im a doctor I knew how Id feel with these things on my chest, knowing there was cancer in them. So I decided on a bilateral mastectomy.

In the end, it was the right choice: there was more cancer that hadnt yet been detected. It was small, sure; but it wouldnt always be small.

The hospital where I would have my surgery started disallowing non-essential surgery the week before my mastectomy was planned. And surgery on anyone who was medically fragile old, ill, likely to respond poorly to anesthesia, etc. was postponed.

I wanted nothing to do with postponing the surgery. I had done everything to make taking those five weeks okay for everyone it affected patients, family, colleagues. Just the thought of redoing all that was exhausting. I had taken the time to take care of me, and dammit, I was going to take care of me!

In the end, it came down to the fact that I was young and healthy going in, so I wouldnt need an ICU bed that was needed for a COVID-19 patient. Id be out the next day. So we went ahead.

On March 19, all my breast tissue was removed.

March and April were spent alternating holding my breath and breathing sighs of relief: biopsy of sentinal nodes revealed no signs of spreading. Testing of the tumor showed it wasnt aggressive enough to require chemotherapy. Because I did what I did when I did it, the cancer was Stage 1. Ill be treated with hormone therapy; Im on Tamoxifen. They got great margins when they did the surgery, and I dont need radiation.

Ask anyone who knows me: Im pretty blunt. Im never unkind, but if a patient wants a lot of touchy-feely handholding, they should probably find another doctor. However. Telling your daughters you have breast cancer is not an occasion for blunt.

Not only was I telling them I was sick, I also knew they would watch me for signs of what was to come for them. Realistic but reassuring is a delicate dance. Fortunately, I was able to be pretty reassuring. It was Stage 1, not a particularly aggressive form, and Id be fine on the other side. But I also wanted to be honest with them about their own health and the screenings theyd need, given their family history.

I could complain about how unfair it is to have bad genetics, or how much it sucks to take care of myself and still have cancer, but I really have a shit happens approach to life, and it served me well. Yelling about how unfair it is as much as I was screaming it on the inside sometimes wasnt going to help me or my kids get through it.

COVID and being isolated together certainly didnt make it easier. This is a hard time for kids their lives are dominated by social things, the groups theyre in, who they communicate with, the things they do. Theyre missing out on things. So managing their emotions and my own is really tough; Im maybe not as patient as I would be otherwise, because Im going through some shit. I have cancer and it sucks. I dont tell them everything because it wouldnt help them. But I try to be open and honest because I know your imagination can sometimes be worse than the truth.

It could be easy to let cancer and COVID take charge and send me screaming to a safe room, but thats really not my style. I take precautions to protect myself from the coronavirus, but Im still seeing patients. I know that as a healthcare professional, Ill get it eventually. I just intend to be at full strength when it happens.

I walk every day, three to five miles with my dog. I run three days a week. Im back in physical therapy because too many hours performing surgery have caused problems with my neck. I truly think staying active has helped with my recovery.

Recovery was tough, not so much because of pain, but because COVID meant my friends and family couldnt help they way they wanted to: they couldnt come clean my house or cook meals, though many dropped meals on my doorstep, rang the bell and ran.

I have two sisters who live locally, and it was killing them not to be able to come and help. One sis is a chef and she just wanted to come and cook for me, but she couldnt come into my house. That was hard, but honestly, it was harder for them than me, since I was pretty out of it for the first two weeks after surgery.

So, yeah, 2020 is a shit year, but at least some things will get easier now. No more mammograms for me, because the reconstruction surgery scheduled for July will be done using my own abdominal tissue. From now on, a check up involves making sure the area around the reconstruction is healthy and cancer-free, including the lymph nodes and chest wall.

I know a lot about health, particularly womens health, because its my job. And I made a lot of decisions, together with my doctors, based on the knowledge I have. I wanted to share a few things that might help others have an easier time of it, COVID or no.

It might not prevent you from having health problems, but being fit can make it easier to handle the treatment and make recovery easier and faster.

Diabetes, cancer, heart disease are all in my family history. Knowing that helped me make better choices. And the KRAS test prompted me to do the MRI that revealed the cancer while it was still early-stage. Knowledge matters.

When I got that pre-diabetes diagnosis, I decided it was time to get a handle on me Ive spent my life caring for others as a doctor, wife, and mom. I was trained in residency to go until you drop. But suddenly I realized I needed to focus on my own health too. I made changes in work and home life, ate better, took meds. I wanted to feel good and I did. And when this came up, I had good endurance, strong muscles, a strong cardiovascular system, even strong legs and abs to help me get out of bed when I couldnt use my arms!

For the past few years, I had managed my sleep patterns to feel better, and through all of this, I managed to for the most part still get good sleep.

Because I made great decisions for a solid few years before this diagnosis, there was a little WTF? that I did everything right and still got this disease. But we live in a toxic world, I hadnt always made great decisions, my work has at times been really stressful, plus, I just had some bad dumb luck. Theres always been that bit of pessimism in me because my family history indicates that I have at least one cancer in my future. But, I thought, this can be dealt with, Im healthy going in, and Ill take this one day at a time.

Ive lost sensation in my chest area. I bump into things, and I dont even know it. Its weird and Im mourning the loss of sensation there, but I knew it would happen, and I was at least somewhat prepared. Make plans. Have a wedge for your bed. Know what the drain looks like coming out of your body. Know who will help you shower and who will make you laugh when your life just has so much yuck in it. Because theres a lot of yuck; youre going to need your sense of humor. And if yours is AWOL, borrow some from a friend.

Just because I knew what was coming doesnt mean I didnt have emotions around it. I had to let myself grieve the loss of my breasts even as I was taking control of the decision to have the bilateral mastectomy. I had to stop being practical and allow myself to mourn.

Living in Seattle, I am blessed with having so many amazing medical professionals in cancer treatment. But I also wanted to work with someone I was comfortable with, someone I trusted with my body, with my future. I needed to feel they were making decisions that worked for me. Please know that youre not hurting a doctors feelings if you decide to move on from them because youre not connecting well with them. It happens all the time, and docs understand how important it is that you feel comfortable. I picked people I felt great with and felt we were making decisions for the same reasons.

Hey, I get a tummy tuck out of this get lemons, make lemonade! Im not exactly going to be voluptuous, but Im good with Bs or even really big As that look nice.

Dont rely on self-breast exams even when I knew where my biggest tumor was, I couldnt feel it. Also, some people are pushing thermograms, claiming theyre safer than mammograms, but they are NOT safer, so do your research before committing. A mammogram isnt perfect, but its a good tool and has saved lives. And you wont get breast cancer from mammograms. The radiation is minimal: you get more from walking around for two weeks in the world. Be informed about your choices before you make them.

I could have put off the reconstruction until next year, when theres a chance COVID-19 will be behind us, and things will be back to whatever normal there is on the other side. But I figured, 2020 is already a hot mess of a year, I might as well shove all the shit into this one and look forward to 2021.

So thats what Im doing. May you get all your shit behind you too. Now go schedule your next screening.

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Im A Physician Who Had Breast Cancer, And Here Are The Knowledge-Based Decisions I Made For Myself - Yahoo Lifestyle

5 Foods that will help you lose weight + recipes – All4Women

Posted: June 25, 2020 at 10:52 pm

Weight loss is technically simply using more calories than you consume, but actually striking the balance can be tricky, even with a food journal and app calculating the calories in every bite you take

Eating healthier foods, packed with nutritional benefits is the best way to satisfy your hunger pangs, because not eating even when youre hungry is unsustainable and generally unhealthy. Here are some nutritious foods to chow down on while youre losing weight.

Fruits and vegetables make up a big part of a healthy diet because theyre brimming with vitamins and nutrients. Theyre also a great weight-loss food because theyre rich in fibre which keeps you feeling fuller for longer and satisfies your hunger on fewer calories.

When choosing your smoothie ingredients keep in mind the sugar content of your ingredients and try to include as many low sugar-high fibre ingredients as possible. Leafy greens and oats are a great start.

Green Cold Buster Smoothie recipe

Chia seeds are small, blackish-grey and get all slimy when wet. Theyre a little on the expensive side, but a spoonful of chia seeds goes a long way.

While youre packing in the satiating fibre, chia seeds are a definite game-changer. With approximately 10g of fibre in just two tablespoons, you could use them to add a major fibre boost to almost any meal.

Chia and Berry Breakfast Pots recipe

It may just look like weak tea, but bone broth is very filling. Its so filling in fact, that some dieters use it as a meal substitute even during liquid diets.

Bone broth has nutritional benefits including being rich in protein and has the benefits of collagen your skin will thank you for. You can drink bone broth like you would a cup of water soup or use it as a base for a low calorie, high nutrient meal.

Throw in some leafy greens and another low-fat protein source and you have a satisfying and nutritious meal that would also make a great fast breaker for intermittent fasting.

Egg, Noodles and Beef Bone Broth recipe

The controversial alkaline diet claims that foods with a natural PH higher than 7 ( alkaline foods) are better for your health because they lower the acidity of the body which is said to create the perfect environment for illness and inflammation to thrive.

Without getting into the veracity of the alkaline diet alkalizing the body, we can definitely appreciate the weight loss benefits of a diet high in raw fruits and veggies that excludes sugar and processed foods.

Alkalising Salad with Zatar Chicken recipe

Soup diets have been a popular weight loss regimen for decades because like all good weight loss foods they are filling and low in calories.

To keep your soup low calorie and high in nutrients, you need to make sure you choose a low-calorie base. Bone broth and tomato-based soups are great because while they add flavour to your soup, they add few calories, giving you room to add nutrient-dense ingredients so you can get the most of your soup.

Tomato, Zucchini, White Bean and Basil Soup recipe

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5 Foods that will help you lose weight + recipes - All4Women

After two miscarriages I gave up comfort food and lost nine stone to fulfil my dream of becoming a mum – The Sun

Posted: June 25, 2020 at 10:52 pm

WHEN a doctor agreed her obesity was likely a factor in her recent miscarriage, Lori-Jay Clark hit rock bottom.

All the 28-year-old teaching assistant had dreamed of was becoming a mum and it was the second baby she had lost in the space of four years.

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She says: In that instant I knew enough was enough.

I was emotionally drained, tired of blaming myself for being obese but not doing anything about it.

The ultimate goal in life for my husband Jimmy and I was to be parents, but I was so unhealthy I knew I couldnt bring a child into the world, mentally or physically. I had to change my ways.

And she did, shedding 9st to go from 20st and a size 22 to 11st and a size 10.

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Lori-Jay, from Hundon, Suffolk, says: Food ruled my life. Id have takeaways four times a week, and order things like a pizza plus a chicken burger, eating till I felt sick.

Deep down, I was furious at myself for sabotaging my chances of being a mum, but I just couldnt stop.

Obesity during pregnancy increases the risk of miscarriage and comes with a one in five chance of losing the baby before 12 weeks.

Lori-Jays overeating began when she was a child, and by age 14 she was 12st and size 14.

She says: I was picked on at school. The boys would say, Dont sit on that, youll break it, and call me fat.

It made me feel worthless, and I turned to food for comfort.

In 2012, Lori-Jay met Jimmy, 30, a bricklayer, at a nightclub.

She says: He wasnt bothered about my weight and would tell me I was beautiful.

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Lori-Jay's diet

Lori- Jay's diet before:

BREAKFAST: 4 slices of toast

LUNCH: Sandwiches, toast

DINNER: Takeaway, pizzas, burgers or ready meals

SNACKS: Biscuits, choc

Lori- Jay's diet now:

BREAKFAST: Fruit & yoghurt

LUNCH: Tuna salad

DINNER: Fakeaways homemade KFC or burger & chips

SNACKS: Quiche, gherkins

But despite being in love and happy with Jimmy, I still couldnt stop overeating.

Wed spend around 100 a week on takeaways, and get through a load of chocolate and crisps while cuddled up on the sofa watching TV.

The couple then started to try for the baby they dreamed of.

Lori-Jay says: When I discovered I was pregnant in May 2016, the feeling was out of this world, I was so happy.

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But a few days after I did the pregnancy test, I started bleeding.

I was rushed to hospital, where scans revealed I had an ectopic pregnancy a fertilised egg had implanted in one of my fallopian tubes.

I needed an operation to urgently remove the egg and tube, which doctors explained could make it harder for me to conceive in future.

Following that shock, the couple took a break from trying for a baby. But when they married the following year, they decided to try again.

In March 2018 though, Lori-Jay suffered a miscarriage at around eight weeks.

She says: I was heartbroken. Wed got so close to having our dream baby, only for the dream to be taken away from us.

Again, Lori-Jay turned to food for comfort.

Id eat till I felt sick, then the guilt and shame would set in, she says. It was a vicious cycle and I lost all confidence in myself.

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Id make excuses to avoid friends, and hide in the street if I saw someone I knew.

The following April, Lori-Jay had another miscarriage at around eight weeks. She says: Deep down, I always blamed myself.

And after going for a check-up, the doctor agreed that I needed to lose weight to be in the best position to carry a baby full-term. That was the wake-up call.

So, in June 2019, Lori-Jay joined a Slimming World group with Jimmy, who by then also weighed 20st.

In the first week I lost 13.5lb, which spurred me on, she says.

We swapped fast food for home-cooked fakeaways and salads and I started attending circuit training classes four times a week.

Lori-Jay now weighs 11st, while Jimmy has dropped to 16st, and doctors have told the couple they have a much better chance of becoming parents.

She says: When I saw that I got to my target weight, I cried. Im so excited for the future.

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Just getting up in the morning was a struggle before because Id feel sluggish.

Now I have so much energy. Jimmy and I are so excited to start trying for a baby again.

I feel like at last our dream of becoming parents is within our grasp.

GOT a story? RING The Sun on 0207 782 4104 or WHATSAPP on 07423720250 or EMAILexclusive@the-sun.co.uk

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After two miscarriages I gave up comfort food and lost nine stone to fulfil my dream of becoming a mum - The Sun

Bomb squad raid in Bingley linked to toxic diet pill – Bradford Telegraph and Argus

Posted: June 25, 2020 at 10:51 pm

POLICE have revealed that an operation on a Bingley Street was in connection with a toxic chemical sometimes used in diet pills.

The bomb squad and police were among those who attended the incident at Percy Street.

Police said a small quantity of the substance, which is poisonous to humans, was found at the property.

A spokesperson for West Yorkshire Police said: At about 10am today (Thursday) police and the Food Standards Agencys National Food Crime Unit attended an address in Percy Street, Bingley, as part of a pre-planned operation.

A search of the property led to the discovery of a small amount of what is believed to be a toxic chemical that is sometimes sold as a diet pill for weight loss.

"It is poisonous to humans and can be unstable if not stored properly.

The substance has since been removed and taken to a location where it has been disposed of safely.

Enquiries are continuing at the address.

People at the scene had earlier speculated that the presence of the bomb disposal unit meant that explosives like a World War Two weapon had been found at the terraced house.

Police said the raid was not terrorism related.

Four plain police cars and seven police officers in plain clothes were on the scene as well as the bomb squad.

An eyewitness said they had been told by an officer: Were not allowed to tell you as yet, were not sure what it is.

I said Army bomb disposal here, is it a World War Two bomb? The officer said No it isnt.

A resident said they had been told it was regarding an unidentified substance.

Martin Storey, 43, who lives on the street, said he had heard someone had found something in a house and they didnt what it was.

One woman said she had asked if they need to be evacuated but was told it was safe to stay where they were.

One Army officer was seen seated talking to plain clothes police officer.

One resident said: "As long as it's not dangerous and not affecting anyone in any way.

"You think automatically, bomb, terrorist attack.

"It's not everyday you see bomb disposal. They obviously think something is going on somewhere.

"It's hard to tell. They've obviously been called for a reason."

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Bomb squad raid in Bingley linked to toxic diet pill - Bradford Telegraph and Argus

Five healthy fats to work into your diet, others to avoid – UT Daily Beacon

Posted: June 25, 2020 at 10:50 pm

Fats a word with stigma around it. Ad campaigns encourage us to eat less fat and become healthier as a result. Eat fat, get fat, as they say.

However, eat fat, get fat is total hokum. Fat is an essential nutrient. Furthermore, low fat foods tend to have more refined sugars.

Fats are necessary, but not all fats are created equal. Here are some examples of healthy fats, as well as some information about unhealthy fats.

Avoid trans fat and saturated fat

Before discussing what to eat, you need to know what to avoid.

Trans fat is to fat what refined sugar is to fruit empty and artificial. Commercial food brands make trans fats through partial hydrogenation, where liquid fats are made solid by adding hydrogen. Except, manufacturers get lazy and dont complete the process, leaving behind an incomplete nutrient that increases bad cholesterol and can lead to heart disease.

Fried foods, butter, lard, chips all foods high in trans fat. Trans fats arent limited to these foods, however. Most packaged or processed food contains some type of trans fat. Basically, if you got it off the shelf and its ready for dinner, its a source of trans fat.

Saturated fats are fine in small doses. Full fat milk and lean red meats contain plenty protein and other essential nutrients. However, saturated fats still increase unhealthy cholesterol. Dont go overboard by eating them multiple times a day. Make your hamburger, tenderloin and steaks proper cheat meals.

Avoid these fats by reading ingredient lists and nutrition labels. Partially hydrogenated is a sneaky way of saying here be trans fat.

Eggs

If there ever was an actual superfood, it would be whole eggs.

The egg nutrition label might as well be a list of almost every essential nutrient. Protein, healthy fat, iron, calcium, vitamins A through E its a whos who of health (minus carbs and vitamin C).

Theyre also versatile. If you dont like them cooked one way, you can cook them another way. Your average, egg-based breakfast satiates even the deepest hunger.

The big concern with eggs is about cholesterol. Eggs are high in cholesterol. However, cholesterol in eggs does not affect cholesterol levels in your blood (unlike trans fat).

The only reason to avoid eggs is allergy. Other than that, they pass every conceivable nutrition test.

Avocados

Avocados are as close you can get to fruit entirely made of fat.

The average large avocado is 322 calories with 29.5 grams of fat. Thats 247 calories from fat alone 77% of total calories. Lucky for us, its all natural. Theyre also a good source of fiber, potassium and antioxidants.

Work avocados into your meal prep if you havent already.

Nuts and seeds

Ah, nuts.

Walnuts, peanuts, pistachios, pecans, almonds all great sources of fat. The average nut serving is 190 calories with 16 grams of fat per ounce. Thats an incredible ratio. Nuts can handle your meals fat component with only a quarter cup.

Shelled nuts like pistachios carry non-nutritional benefits. Because you need to remove their shells, you have to eat slowly and think about what youre consuming. This encourages healthier eating habits.

Chia seeds are similar. An ounce contains 9 grams of fat, making up 80% of total calories while also providing fiber.

Tofu

Tasty and infinitely customizable, tofu is a go-to source of vegan protein. Its also a great source of healthy fat.

Three ounces of tofu contains up to 6 grams of fat with only 1 gram of saturated fat. All while being a plant-based source of protein.

Its versatility lets you cook with any sort of vegetable, bean, lentil or chickpea. Its more than a meat substitute. Its good food in its own right

Fish

Salmon, trout, mackerel, herring, sardines, cod and tuna are swimming in healthy, omega-3 fatty acids. Being animal products, theyre also stuffed to the gills with high quality protein.

Furthermore, those who eat fish are at lower risk of heart disease.

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Five healthy fats to work into your diet, others to avoid - UT Daily Beacon

What Is The Mayr Method Diet Rebel Wilson Is Using To Lose Weight? – Women’s Health

Posted: June 25, 2020 at 10:50 pm

Rebel Wilson is deep into her Year of Health and she looks utterly amazing. While Rebel has shared pics on Instagram of herself exercising, she hasnt given a ton of details on how shes working toward her goal to get down to 165 pounds by the end of the year. Now, theres some info on what, exactly, shes been up to.

According to People, Rebel is losing weight using something called the Mayr Method. Awesome! Butasking for a friend who happens to be me here: What is the Mayr Method? Heres the deal.

The Mayr Method has actually been around in some form for ages. Its based on the Mayr Cure, which was created by an Austrian doctor named Franz Xaver Mayr (sometimes referred to as F.X. Mayr). Mayrs philosophy is that most people poison their digestive systems with the foods they eat and how they eat them.

Now, the Mayr Method is promoted at Viva Mayr, an upscale wellness facility with locations around the world. Viva Mayr combines modern complementary medicine with traditional diagnostics and therapies according to F.X. Mayr, the official Viva Mayr website says. Once we have treated your condition, proper nutrition combined with exercise and improved mental awareness become the building blocks of your new life.

The Viva Mayr Diet: 14 Days to a Flatter Stomach and a Younger You

The diet's philosophy focuses on eating well and considering your gut health an important part of your overall health. It works to get followers to stop snacking, reduce their gluten and dairy intake, and to even chew their foods longer, according to The Guardian.

It all starts off with a sugar and caffeine detox, according to Womens Health UK. It also focuses on some lifestyle changes, like focusing on chewing every bite 40 to 60 times. (The goal is to get you to chew slower and be more mindful about your food, Womens Health UK says.) Reading, talking, or looking at your phone while you eat are forbidden, Womens Health UK says (again, the whole mindfulness thing).

Meals include whole foods that are high alkaline, like veggies and fish, The Guardian says.

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A visit to a swanky Viva Mayr facility for a consultation will set you back about $211, per The Guardian, and overnight stays will run you way more. But there's also a book called The Viva Mayr Diet that breaks down the basics of the diet. So, there's that.

Apparently shes not just spending a lot of time chewing her foodshes also working out regularly. She exercises with a personal trainer up to six times a week, goes on walks, and is trying to up her protein intake nutritionally, a source told People. I know she's also been working on conquering her emotional eating patterns of behavior.

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What Is The Mayr Method Diet Rebel Wilson Is Using To Lose Weight? - Women's Health

The Real-Life Diet of David Dobrik, Who is Skipping Workouts and Eating Watermelon Sandwiches – GQ

Posted: June 25, 2020 at 10:50 pm

Its very difficult not to laugh while talking to David Dobrik. After just a few minutes of talking, the charm and sincerity that made the low-key everyman a YouTube sensation are clear. And, sincerely: He is not a gym rat. I was supposed to work out with my trainer today, but you called so I cancelled on it, he says. So, thank God for that.

He got his start on Vine, but Dobrik is best known for his YouTube vlogs, which have gone from pranks on his friends to and giving away cars and driving around L.A. with Kylie Jenner. Over the years hes amassed almost 18 million subscribers on YouTube, spinning the aforementioned charm to a truly massive audience. However, since the beginning of the COVID-19 pandemic, Dobrik stopped making vlogs. Hes decided to pause on his YouTube channel and take some time to experiment with other platforms and stay safe from the virus.

He talked to GQ on how hes filling his days during the pandemic, dealing with the stress of the YouTube grind, and winding down with his favorite candle.

GQ: What's your average day look like during the pandemic?

David Dobrik: My average day feels like it's just day and night. During the day, I'm waiting for it to become night and then at night, I'm waiting for it to become morning. It's getting so repetitive.

Usually I wake up around 10 or 11. I work with my roommate and we'll get on some Zoom calls. And then usually they'll go out and go on a run or they'll go work in the backyard and I'll make some sort of excuse where I have to shower, or I have to do some more important things [laughs]. But there have been a lot of days in a row where I've used some excuses to skip that part of the day.

Actually, I was supposed to work out with my trainer today, but you called so I cancelled on it. So, thank God for that.

Happy I could do that for you.

Next month, you know, I'll work with the trainer next month. There's gonna be lots of months in the future. I'm not the best at working out. I absolutely hate working out. I should say that: I hate lifting weights. I hate doing sit ups. I just dont understand activities where there's no clear goal or game involved. I love, love playing basketball and soccer. I love sports for a purpose and there's a winner or a loser in that moment. There's something about lifting weights that I find it's so boring. I just end up getting so angry by the end of it.

That's so funny to me, part of me has been dying during this whole thing because I can't lift weights. I'm like: Im gonna go to the gym and I have this super structured program that I'm following. It's all about certain numbers I need to be hitting.

Why do you do it? Are you seeing serious body changes? Is it like, the second you see a little change in your body you're addicted to it now? How does that work?

I enjoy the numbers aspect of it. I love watching like the strength gains you can makebeing like last month I couldn't lift this but now I can.

What you've done is you've built a game into what you're doing. So you go and you're competing against yourself, which is cool. I could never do it [laughs].

This is a me thing. I don't think anybody's ever had this problem, but when I grip weights and I'm like "Okay, I'm benching something." I get really in my head. I think about my hand around the weight and I think about how my veins are bending around the weight, and how the inside of my hand is looking and it grosses me out so much.

I don't think Ive ever heard somebody say that before.

I really love tennis, and tennis before quarantine happened. The courts were open and I could go out with a pro to play. It's a three-in-one because you get a work out, you have fun, and you get a tan. My favorite part about coming back from tennis is looking tan. I don't know why, I just love it, it feels like an added bonus.

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The Real-Life Diet of David Dobrik, Who is Skipping Workouts and Eating Watermelon Sandwiches - GQ

New Peer-Reviewed Research Shows Fasting Mimicking Diets May Enhance Effectiveness of Chemotherapy in Cancer Patients, While Reducing Some Side…

Posted: June 25, 2020 at 10:50 pm

LOS ANGELES, June 25, 2020 /PRNewswire/ --A groundbreaking clinical trial is providing insight into the potential effects of a Fasting Mimicking Diet(FMD) for breast cancer patients that may help make chemotherapy work more effectively against cancer and potentially help to shield healthy cells from damage during chemotherapy. Nature Communications published the results of The DIRECT study, which builds upon extensive preclinical evidence supporting that fasting and FMDs prior to chemotherapy may have a beneficial effect on both the efficacy of a wide variety of cancer therapies ranging from chemotherapy to kinase inhibitors and on the reduction of the side effects caused by various cancer treatments.

"This revelatory study on the benefits of a plant-based, Fasting Mimicking Diet during chemotherapy may represent a major breakthrough for women undergoing breast cancer treatments," said breast surgeon Dr. Kristi Funk, former director of the Breast Center at Cedars-Sinai Medical Center. "This study supports the concept that FMD creates the metabolic environment that supports chemo's ability to destroy cancer cells while minimizing the collateral damage to normal cells. With a FMD, you get to eat, so you're not too hangry, but your cells still respond as if you're strictly fasting."

What researchers found

"This research essentially found that fasting switches healthy cells from a busy, proliferative state to a quiet, maintenance mode. Why? There's low level of nutrient and insulin around, so it's time to conserve energy. Malignant cells, however, don't listen to these body's signals and don't respond to food scarcity by entering this protective mode. Because chemo targets cells that divide quickly, when you receive it in a fasted state, it should sail past quiet healthy cells and more effectively target the busy cancer cells," added Dr. Funk.

This randomized controlled study included 129 patients with HER2 negative breast cancer, 65 of whom were assigned to the group receiving the FMD three days prior to, and the day of chemotherapy and 64 patients who continued their regular diet.

The data indicates that a 90-100% tumor cell death was three to four times more likely to occur in patients who were adherent to three FMD cycles, and the more cycles of FMDs the patients adhered to, the higher percentage of tumor cell loss was reported.

The difference achieved by fasting

Fasting helps normal cells stay off replicative mode which protects them from chemotherapy toxicity. On the other hand, cancer cells by definition cannot stop replicating and get more exposed to chemotherapy. This breakthrough discovery by professor Valter Longo, one of TIME Magazine's 50 Most Influential People in Health Care, known as 'Differential Stress Resistance' or DSS, could present a new avenue for oncologists and patients to fight a range of cancers.

"The results in this study are remarkable and consistent with those in mice in the overall body of research, especially those indicating that the portion of patients who responded well to chemotherapy is much higher in the group who completed most or all cycles of the FMD," said Professor Longo, director of the University of Southern California's Longevity Institute and a DIRECT study co-author who discovered the effect of fasting and FMDs in the protection of normal cells and sensitization of cancer cells.

The technology of Fasting Mimicking Diets are the result of decades of research at USC on nutrients and genes that regulate aging and resist cellular stress. It is a plant-based regimen that nourishes the body while keeping it in a fasting mode to deliver differential effects on all normal and cancer cells. The Fasting Mimicking Diet is one of the leading technologies by L-Nutra, a USC spinoff company dedicated to enhancing human health and longevity.

About L-Nutra

L-Nutra is leading the discovery, design, and commercialization of novel, plant-based nutrition programs and therapeutics to enhance human healthspan up to 100 years. L-Nutra translates the science behind Fasting Mimicking Dietand Nutrition For Longevitywith breakthrough discoveries in cellular-level nutrient signalling pathways to promote healthy aging technologies and to advance the development of therapeutic solutions for age-related diseases. For more information visit http://www.l-nutra.com

SOURCE L-Nutra

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