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How Ayurveda can help you stay healthy: Expert’s tips to improve skin, hair, and diet through natural medicine – Times Now

Posted: June 14, 2020 at 5:49 am

How Ayurveda can help you stay healthy: Expert's tips to improve skin, hair, and diet through natural medicine  |  Photo Credit: iStock Images

New Delhi: The natural mechanism of our body is such that it adjusts to the weather. However, hot and humid weather can cause oily and itchy skin, tanning, and sweating. It can also result in body odour. Hair and digestive problems also become common during the summer season. Unrestricted sun exposure, even during monsoon, can cause premature ageing in all skin types whileoily skin may experience heavy breakouts. Your hair, nails, lips, and eyes, as well as your digestive system, can get affected in the hot and humid weather. Therefore, we need to take care of our skin and limit exposure to the sun, and at the same time, take care of overall health in a natural way.

Our face is the first thing people notice and it seems that the sunrays are no different. Therefore, this part of the body bears the brunt, quite literally. Make sure you are washing you face more with plain water for 3-4 times every day. Not only it helps your body to cool off, it takes off the dirt and grime that clog the pores and prevent thesweat glands from working. Unless these glands work, your skin will not breathe and therefore, will not be healthy. You must also use a natural exfoliator to make sure dead skin cellsare off your face. You may use a homemade mix of gram flour and curd. If you have acne-prone skin, use a mix containing fullers earth (Multani mitti), sandal, rose water and basil. For dry and matured skin, choose egg white, lemon, sandal and curd with a pinch of turmeric and gram flour. However, if you have a sunburn or eruption or broken skin, wait for the area to heal before applying anything.

Though oil is not advisable for your hair during this time of the year, they are perfectly suited to cover your skin and protect it from harmful sun rays, just like SPF in sunscreen lotions. Many consider sunscreens redundant in monsoon but it prevents your skin from unwanted heat. Sunscreens available in the market are said to contain chemicals such as oxybenzone that leave an adverse impact on the hormones. Few indicative natural alternatives of SPF are:

Due to sweat, ambient humidity and dirt, our hair looks dull and limp in monsoon. Many of us also experience more dandruff. While using lemon is an age-old and tested method, fenugreek or methi seeds are also effective in resolving dandruff. It is not advisable to shampoo your hair very frequently as it takes out moisture and dries the scalp. But make sure you wash your hair with a mild shampoo. If you have an oily scalp, avoid using oil of any kind. Those who experience hair fall during monsoon can apply a natural mask of neem paste, a paste of hibiscus flower and leaves, powdered amla, reetha, shikakai, and eggs. Apply this from root to end of the hair, leave for an hour and wash off with a mild shampoo.

Sultry weather during monsoon often makes it difficult to digest the food we eat and result in food poisoning and indigestion. Eat light as eating rich, spicy food and leave some room in your stomach. Maintain a routine for meals and take small frequent meals instead of one or two heavy meals. At night, make sure your diet is light but has enough nutrition. Seasonal fruits and vegetables are the best way to beat a seasonal disease. Run your blender if you are short of time fresh juice of fruits and vegetables are a good alternative and give an equal amount of nutrition and keep you hydrated. Drink plenty of water, tender coconut water to avoid dehydration caused by endless sweating, but avoid alcohol and cold drinks. Mix some sugar and salt with plain water this will help maintain hydration and ensure electrolyte balance in your body.

Dr Bhushan Bhavsar is a guest contributor. Views expressed are personal.

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How Ayurveda can help you stay healthy: Expert's tips to improve skin, hair, and diet through natural medicine - Times Now

Novel oral testosterone therapy shows liver health benefits – Urology Times

Posted: June 13, 2020 at 10:52 am

A novel lymphatically delivered oral testosterone undecanoate (Tlando) is a fixed-dose, well-tolerated, and effective treatment for hypogonadism with liver health benefits that clearly differentiate it from the potentially hepatotoxic oral methyltestosterone, reported Irwin Goldstein, MD, at the American Urological Association 2020 Virtual Experience.

This innovative product has exciting, paradigm-shifting potential for treating men with low testosterone, said Goldstein, director of Sexual Medicine at Alvarado Hospital in San Diego, California, and clinical professor of surgery at the University of California San Diego.

It offers the opportunity to provide safe, effective, and well-tolerated testosterone replacement through the oral route that is the generally preferred method for medication administration. In addition, available data indicate that it not only avoids the adverse hepatic effects that have historically limited use of oral testosterone, but it improves markers of nonalcoholic fatty liver disease [NAFLD] that is a serious and prevalent condition. Low testosterone (ie, hypogonadism) is common in males with NAFLD.

Methyltestosterone is prone to cause liver toxicity with oral ingestion because it is directly transported to the liver through the portal vein, Goldstein said. In contrast, the lymphatically delivered oral testosterone undecanoate is a nonmethylated prodrug of endogenous testosterone, found in Tlando, that avoids first-pass metabolism in the liver and enters the systemic circulation via the lymphatics.

The safety and efficacy of Tlando for treating men with low testosterone was investigated in the 1-year SOAR trial that included 210 men who received the investigational product and a control group of 105 patients treated with topical testosterone gel.

Results from SOAR showed that the oral testosterone undecanoate was associated with a significantly greater increase in free testosterone levels compared with the topical product, and it improved key mental and sexual domains, reported Goldstein, who was an investigator in SOAR and an earlier dosing study.

Safety data in the study included measurement of liver enzymes and showed that reductions were consistently achieved in alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, and -glutamyl transferase among men who had elevated levels of those markers of liver injury at baseline. Rates of normalization for those 4 enzymes ranged from 31% for -glutamyl transferase to 67% for alkaline phosphatase.

40% reduction in liver fat at 4 months

Additional data on the liver effects of the novel testosterone undecanoate product were obtained in a smaller separate trial of men with hypogonadism. Using the objective Magnetic Resonance Imaging Proton Density Fat Fraction technique to measure liver fat percentage, it found that after 4 months, men with NAFLD at baseline achieved an approximately 40% reduction in liver fat. In addition, more than 75% of men who entered the study with NAFLD were considered responders to the oral testosterone undecanoate based on achieving a 30% or greater reduction in the percentage of liver fat.

In addition, the percentage of patients categorized as NAFLD-free rose during the study and nearly doubled by its conclusion, increasing from 34% at baseline to reach 63% at 16 weeks.

Interestingly, the higher the baseline body mass index, the greater the reduction in liver fat achieved with Tlando treatment, and it appears that the improvement in liver fat does not appear to be explained by any decrease in body weight, Goldstein said.

Disclosures: Lipocine Inc provided funding for the study. Goldstein is on the consultant/advisory board of Lipocine Inc, does research for AbbVie Inc and Marius Pharmaceuticals LLC, is on the Clarus Therapeutics, Inc speakers bureau, and receives writing support from Endo International.

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Novel oral testosterone therapy shows liver health benefits - Urology Times

Testosterone Replacement Therapy Market Overview and Outlook Report by 2026 – Weekly Wall

Posted: June 13, 2020 at 10:52 am

Testosterone Replacement Therapy

In a recent study published by QY Research, titled Global Testosterone Replacement Therapy MarketResearch Report, analysts offer an in-depth analysis of the global Testosterone Replacement Therapy market. The study analyzes the various aspects of the market by studying its historic and forecast data. The research report provides a Porters five force model, SWOT analysis, and PESTEL analysis of the Testosterone Replacement Therapy market. The different areas covered in the report are Testosterone Replacement Therapy market size, drivers and restraints, segment analysis, geographic outlook, major manufacturers in the market, competitive landscape, value/volume data, marketing strategies, and expert views

Major Key Player operating in this report are: AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, Kyowa Kirin, Acerus Pharmaceuticals

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Segmental Analysis

The report has classified the global Testosterone Replacement Therapy industry into segments including product type and application. Every segment is evaluated based on growth rate and share. Besides, the analysts have studied the potential regions that may prove rewarding for the Testosterone Replacement Therapy manufacturers in the coming years. The regional analysis includes reliable predictions on value and volume, thereby helping market players to gain deep insights into the overall Testosterone Replacement Therapy industry.

Global Testosterone Replacement Therapy Market Segment By Type:

, Gels, Injections, Patches, Other

Global Testosterone Replacement Therapy Market Segment By Application:

, Hospitals, Clinics, Others Key Players: The Key manufacturers that are operating in the

In terms of region, this research report covers almost all the major regions across the globe such as North America, Europe, South America, the Middle East, and Africa, and the Asia Pacific. Europe and North America regions are anticipated to show an upward growth in the years to come. While Testosterone Replacement Therapy market in Asia Pacific regions is likely to show remarkable growth during the forecasted period. Cutting edge technology and innovations are the most important traits of the North America region and thats the reason most of the time the US dominates the global markets. The keyword market in the South, America region is also expected to grow in the near future.

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Key companies operating in the global Testosterone Replacement Therapy market include: AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, Kyowa Kirin, Acerus Pharmaceuticals

Key questions answered in the report:

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What are the key challenges that the global Testosterone Replacement Therapy market may face in the future?

Which are the leading companies in the global Testosterone Replacement Therapy market?

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Tables of ContentTable of Contents 1 Testosterone Replacement Therapy Market Overview1.1 Product Overview and Scope of Testosterone Replacement Therapy1.2 Testosterone Replacement Therapy Segment by Type1.2.1 Global Testosterone Replacement Therapy Sales Growth Rate Comparison by Type (2021-2026)1.2.2 Gels1.2.3 Injections1.2.4 Patches1.2.5 Other1.3 Testosterone Replacement Therapy Segment by Application1.3.1 Testosterone Replacement Therapy Sales Comparison by Application: 2020 VS 20261.3.2 Hospitals1.3.3 Clinics1.3.4 Others1.4 Global Testosterone Replacement Therapy Market Size Estimates and Forecasts1.4.1 Global Testosterone Replacement Therapy Revenue 2015-20261.4.2 Global Testosterone Replacement Therapy Sales 2015-20261.4.3 Testosterone Replacement Therapy Market Size by Region: 2020 Versus 2026 2 Global Testosterone Replacement Therapy Market Competition by Manufacturers2.1 Global Testosterone Replacement Therapy Sales Market Share by Manufacturers (2015-2020)2.2 Global Testosterone Replacement Therapy Revenue Share by Manufacturers (2015-2020)2.3 Global Testosterone Replacement Therapy Average Price by Manufacturers (2015-2020)2.4 Manufacturers Testosterone Replacement Therapy Manufacturing Sites, Area Served, Product Type2.5 Testosterone Replacement Therapy Market Competitive Situation and Trends2.5.1 Testosterone Replacement Therapy Market Concentration Rate2.5.2 Global Top 5 and Top 10 Players Market Share by Revenue2.5.3 Market Share by Company Type (Tier 1, Tier 2 and Tier 3)2.6 Manufacturers Mergers & Acquisitions, Expansion Plans2.7 Primary Interviews with Key Testosterone Replacement Therapy Players (Opinion Leaders) 3 Testosterone Replacement Therapy Retrospective Market Scenario by Region3.1 Global Testosterone Replacement Therapy Retrospective Market Scenario in Sales by Region: 2015-20203.2 Global Testosterone Replacement Therapy Retrospective Market Scenario in Revenue by Region: 2015-20203.3 North America Testosterone Replacement Therapy Market Facts & Figures by Country3.3.1 North America Testosterone Replacement Therapy Sales by Country3.3.2 North America Testosterone Replacement Therapy Sales by Country3.3.3 U.S.3.3.4 Canada3.4 Europe Testosterone Replacement Therapy Market Facts & Figures by Country3.4.1 Europe Testosterone Replacement Therapy Sales by Country3.4.2 Europe Testosterone Replacement Therapy Sales by Country3.4.3 Germany3.4.4 France3.4.5 U.K.3.4.6 Italy3.4.7 Russia3.5 Asia Pacific Testosterone Replacement Therapy Market Facts & Figures by Region3.5.1 Asia Pacific Testosterone Replacement Therapy Sales by Region3.5.2 Asia Pacific Testosterone Replacement Therapy Sales by Region3.5.3 China3.5.4 Japan3.5.5 South Korea3.5.6 India3.5.7 Australia3.5.8 Taiwan3.5.9 Indonesia3.5.10 Thailand3.5.11 Malaysia3.5.12 Philippines3.5.13 Vietnam3.6 Latin America Testosterone Replacement Therapy Market Facts & Figures by Country3.6.1 Latin America Testosterone Replacement Therapy Sales by Country3.6.2 Latin America Testosterone Replacement Therapy Sales by Country3.6.3 Mexico3.6.3 Brazil3.6.3 Argentina3.7 Middle East and Africa Testosterone Replacement Therapy Market Facts & Figures by Country3.7.1 Middle East and Africa Testosterone Replacement Therapy Sales by Country3.7.2 Middle East and Africa Testosterone Replacement Therapy Sales by Country3.7.3 Turkey3.7.4 Saudi Arabia3.7.5 U.A.E 4 Global Testosterone Replacement Therapy Historic Market Analysis by Type4.1 Global Testosterone Replacement Therapy Sales Market Share by Type (2015-2020)4.2 Global Testosterone Replacement Therapy Revenue Market Share by Type (2015-2020)4.3 Global Testosterone Replacement Therapy Price Market Share by Type (2015-2020)4.4 Global Testosterone Replacement Therapy Market Share by Price Tier (2015-2020): Low-End, Mid-Range and High-End 5 Global Testosterone Replacement Therapy Historic Market Analysis by Application5.1 Global Testosterone Replacement Therapy Sales Market Share by Application (2015-2020)5.2 Global Testosterone Replacement Therapy Revenue Market Share by Application (2015-2020)5.3 Global Testosterone Replacement Therapy Price by Application (2015-2020) 6 Company Profiles and Key Figures in Testosterone Replacement Therapy Business6.1 AbbVie6.1.1 Corporation Information6.1.2 AbbVie Description, Business Overview and Total Revenue6.1.3 AbbVie Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.1.4 AbbVie Products Offered6.1.5 AbbVie Recent Development6.2 Endo International6.2.1 Endo International Testosterone Replacement Therapy Production Sites and Area Served6.2.2 Endo International Description, Business Overview and Total Revenue6.2.3 Endo International Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.2.4 Endo International Products Offered6.2.5 Endo International Recent Development6.3 Eli lilly6.3.1 Eli lilly Testosterone Replacement Therapy Production Sites and Area Served6.3.2 Eli lilly Description, Business Overview and Total Revenue6.3.3 Eli lilly Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.3.4 Eli lilly Products Offered6.3.5 Eli lilly Recent Development6.4 Pfizer6.4.1 Pfizer Testosterone Replacement Therapy Production Sites and Area Served6.4.2 Pfizer Description, Business Overview and Total Revenue6.4.3 Pfizer Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.4.4 Pfizer Products Offered6.4.5 Pfizer Recent Development6.5 Actavis (Allergan)6.5.1 Actavis (Allergan) Testosterone Replacement Therapy Production Sites and Area Served6.5.2 Actavis (Allergan) Description, Business Overview and Total Revenue6.5.3 Actavis (Allergan) Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.5.4 Actavis (Allergan) Products Offered6.5.5 Actavis (Allergan) Recent Development6.6 Bayer6.6.1 Bayer Testosterone Replacement Therapy Production Sites and Area Served6.6.2 Bayer Description, Business Overview and Total Revenue6.6.3 Bayer Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.6.4 Bayer Products Offered6.6.5 Bayer Recent Development6.7 Novartis6.6.1 Novartis Testosterone Replacement Therapy Production Sites and Area Served6.6.2 Novartis Description, Business Overview and Total Revenue6.6.3 Novartis Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.4.4 Novartis Products Offered6.7.5 Novartis Recent Development6.8 Teva6.8.1 Teva Testosterone Replacement Therapy Production Sites and Area Served6.8.2 Teva Description, Business Overview and Total Revenue6.8.3 Teva Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.8.4 Teva Products Offered6.8.5 Teva Recent Development6.9 Mylan6.9.1 Mylan Testosterone Replacement Therapy Production Sites and Area Served6.9.2 Mylan Description, Business Overview and Total Revenue6.9.3 Mylan Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.9.4 Mylan Products Offered6.9.5 Mylan Recent Development6.10 Upsher-Smith6.10.1 Upsher-Smith Testosterone Replacement Therapy Production Sites and Area Served6.10.2 Upsher-Smith Description, Business Overview and Total Revenue6.10.3 Upsher-Smith Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.10.4 Upsher-Smith Products Offered6.10.5 Upsher-Smith Recent Development6.11 Ferring Pharmaceuticals6.11.1 Ferring Pharmaceuticals Testosterone Replacement Therapy Production Sites and Area Served6.11.2 Ferring Pharmaceuticals Testosterone Replacement Therapy Description, Business Overview and Total Revenue6.11.3 Ferring Pharmaceuticals Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.11.4 Ferring Pharmaceuticals Products Offered6.11.5 Ferring Pharmaceuticals Recent Development6.12 Kyowa Kirin6.12.1 Kyowa Kirin Testosterone Replacement Therapy Production Sites and Area Served6.12.2 Kyowa Kirin Testosterone Replacement Therapy Description, Business Overview and Total Revenue6.12.3 Kyowa Kirin Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.12.4 Kyowa Kirin Products Offered6.12.5 Kyowa Kirin Recent Development6.13 Acerus Pharmaceuticals6.13.1 Acerus Pharmaceuticals Testosterone Replacement Therapy Production Sites and Area Served6.13.2 Acerus Pharmaceuticals Testosterone Replacement Therapy Description, Business Overview and Total Revenue6.13.3 Acerus Pharmaceuticals Testosterone Replacement Therapy Sales, Revenue and Gross Margin (2015-2020)6.13.4 Acerus Pharmaceuticals Products Offered6.13.5 Acerus Pharmaceuticals Recent Development 7 Testosterone Replacement Therapy Manufacturing Cost Analysis7.1 Testosterone Replacement Therapy Key Raw Materials Analysis7.1.1 Key Raw Materials7.1.2 Key Raw Materials Price Trend7.1.3 Key Suppliers of Raw Materials7.2 Proportion of Manufacturing Cost Structure7.3 Manufacturing Process Analysis of Testosterone Replacement Therapy7.4 Testosterone Replacement Therapy Industrial Chain Analysis 8 Marketing Channel, Distributors and Customers8.1 Marketing Channel8.2 Testosterone Replacement Therapy Distributors List8.3 Testosterone Replacement Therapy Customers 9 Market Dynamics 9.1 Market Trends 9.2 Opportunities and Drivers 9.3 Challenges 9.4 Porters Five Forces Analysis 10 Global Market Forecast10.1 Global Testosterone Replacement Therapy Market Estimates and Projections by Type10.1.1 Global Forecasted Sales of Testosterone Replacement Therapy by Type (2021-2026)10.1.2 Global Forecasted Revenue of Testosterone Replacement Therapy by Type (2021-2026)10.2 Testosterone Replacement Therapy Market Estimates and Projections by Application10.2.1 Global Forecasted Sales of Testosterone Replacement Therapy by Application (2021-2026)10.2.2 Global Forecasted Revenue of Testosterone Replacement Therapy by Application (2021-2026)10.3 Testosterone Replacement Therapy Market Estimates and Projections by Region10.3.1 Global Forecasted Sales of Testosterone Replacement Therapy by Region (2021-2026)10.3.2 Global Forecasted Revenue of Testosterone Replacement Therapy by Region (2021-2026)10.4 North America Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.5 Europe Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.6 Asia Pacific Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.7 Latin America Testosterone Replacement Therapy Estimates and Projections (2021-2026)10.8 Middle East and Africa Testosterone Replacement Therapy Estimates and Projections (2021-2026) 11 Research Finding and Conclusion 12 Methodology and Data Source 12.1 Methodology/Research Approach 12.1.1 Research Programs/Design 12.1.2 Market Size Estimation 12.1.3 Market Breakdown and Data Triangulation 12.2 Data Source 12.2.1 Secondary Sources 12.2.2 Primary Sources 12.3 Author List 12.4 Disclaimer

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Testosterone Replacement Therapy Market Overview and Outlook Report by 2026 - Weekly Wall

QOL and body composition benefits seen with novel oral T treatment – Urology Times

Posted: June 13, 2020 at 10:52 am

New data from phase 3 clinical trials provide further evidence supporting the safety and effectiveness of the first-to-market oral testosterone undecanoate treatment for hypogonadism (Jatenzo), reported Stanton Honig, MD.

Honig presented results for secondary end points from 2 randomized studies comparing the lipoprotein-coated testosterone undecanoate formulation with topical testosterone treatments showing that both the oral and gel products were associated with statistically significant improvements in psychosocial well-being and bone and body composition parameters. Safety analyses showed the oral testosterone undecanoate was associated with a modest increase in blood pressure, which was slightly higher in men with hypertension at study entry than in men with normal blood pressure and that neither the oral nor gel testosterones had any significant effect on liver function test results.

This novel formulation of testosterone undecanoate is a first-in-class oral testosterone replacement that does not have liver issues, said Honig, professor of clinical urology and director, Mens Health, Yale University School of Medicine, New Haven, Connecticut.

Taken twice daily, it provides hypogonadal men with total testosterone concentrations in the mid-eugonadal range. Its safety profile is generally consistent with injectable and topical testosterone preparations, although the product labeling for oral testosterone undecanoate includes a black box warning about the potential for increased blood pressure. The data collected in the oral testosterone undecanoate studies underscore the need to check blood pressure at some point in men who are started on this therapy, especially those who are hypertensive at baseline.

The 2 trials comprised a 4-month study and a 12-month investigation. Eligibility criteria were similar in the 2 trials. Men ages 18 to 65 years (to 75 years in the 12-month study) were included if they had hypogonadism (serum testosterone <300 ng/dL on 2 morning samples approximately 7 days apart), had signs and symptoms consistent with hypogonadism, and were either naive to or underwent washout from testosterone therapy.

The 4-month study randomized 222 men 3:1 to oral testosterone undecanoate 237 mg twice daily or once-daily topical testosterone solution. A total of 325 men were randomized 1:1 to oral testosterone undecanoate 200 mg twice daily or topical testosterone gel in the 12-month trial. Dose adjustments were allowed based on serum testosterone levels.

The 4 treatment groups were similar with respect to demographics and clinical characteristics in terms of baseline age, body mass index, comorbidities (prediabetes, diabetes, and hypertension), and mean baseline testosterone levels. Time-weighted average testosterone concentration increased to reach mid-eugonadal levels in all 4 treatment groups, with values ranging from 425 ng/dL to 524 ng/dL across all 4 study groups.

Data on psychosocial well-being were collected in both trials using the Psychosexual Daily Questionnaire. Results showed statistically significant improvements from baseline to study completion in mood, sexual desire, weekly sexual activity, and sexual energy with and without a partner with both the oral and topical treatments, Honig reported.

General well-being was evaluated in the 12-month study using the 36-Item Short Form Health Survey questionnaire. In the individual domains, statistically significant improvements were achieved in both the oral testosterone undecanoate and testosterone gel group and occurred in physical functioning, physical and emotional role limitation, social functioning, and bodily pain.

Changes in body composition parameters were also investigated in the 12-month study. The results for the oral testosterone undecanoate group showed spine bone mineral density, hip bone mineral density, lean body mass, and fat mass all improved significantly from baseline at 6 months with further improvements achieved at month 12.

Both the oral testosterone undecanoate and topical testosterone treatments were associated with minimal increases in serum prostate-specific antigen. Overall, the oral and topical treatments were associated with an increase of hematocrit in approximately 5% to 6% of patients.

Importantly, there were no clinical events associated with the hematocrit increases in the oral testosterone undecanoate or the testosterone gel group, nor did any patient discontinue treatment because of elevated hematocrit, Honig said.

Changes in blood pressure were followed using ambulatory monitoring. Among men treated with oral testosterone undecanoate, mean changes in 24-hour systolic and diastolic blood pressure were approximately 5 mm Hg and 2.5 mm Hg, respectively. Comparisons between men with and without hypertension at baseline showed that the average change was slightly higher in the hypertensive group.

Honig said, It is unclear whether the blood pressure rise is just for oral testosterone undecanoate or a general class effect, as it has been seen with subcutaneous testosterone preparations as well. Most importantly, both oral testosterone undecanoate and topical gel groups showed no significant changes in liver enzyme measurements over a 12-month period.

Disclosure: Honig is a consultant to Clarus Therapeutics and Endo.

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QOL and body composition benefits seen with novel oral T treatment - Urology Times

Trending now: Testosterone Replacement Therapy Market: Business Size, Future Trends, Share and Global Analysis by Forecast: AbbVie, Endo…

Posted: June 13, 2020 at 10:52 am

Testosterone Replacement Therapy Market 2020: Latest Analysis

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Top Players of Testosterone Replacement Therapy Market are Studied: AbbVieEndo InternationalEli lillyPfizerActavis (Allergan)BayerNovartisTevaMylanUpsher-SmithFerring PharmaceuticalsKyowa KirinAcerus Pharmaceuticals

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Global Testosterone Replacement Therapy Market is estimated to reach xxx million USD in 2020 and projected to grow at the CAGR of xx% during 2020-2026. According to the latest report added to the online repository of Report Hive Research the Testosterone Replacement Therapy market has witnessed an unprecedented growth till 2020. The extrapolated future growth is expected to continue at higher rates by 2026.

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Segmentation by Application: HospitalsClinicsOthers

Segmentation by Type: GelsInjectionsPatchesOther

NOTE:Due to the pandemic, we have included a special section on the Impact of COVID 19 on the Testosterone Replacement Therapy Market which would mention How the Covid-19 is Affecting the Testosterone Replacement Therapy Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Covid-19 Impact on Key Regions and Proposal for Testosterone Replacement Therapy Players to Combat Covid-19 Impact.

The Essential Content Covered in the GlobalTestosterone Replacement Therapy Market Report:

* Top Key Company Profiles.* Main Business and Rival Information* SWOT Analysis and PESTEL Analysis* Production, Sales, Revenue, Price and Gross Margin* Market Share and Size

The global Testosterone Replacement Therapy market was valued at $XX million in 2019, and Our analysts predict the global market size will reach $XX million by the end of 2029, growing at a CAGR of XX% between 2019 and 2029.

Since the COVID-19 virus outbreak in December 2019, the disease has spread to over 210 countries and territories around the world and 2 international conveyances. The global impacts of COVID-19 are already starting to be felt, and will significantly affect this industry in 2020.

This report analyses the impact of COVID-19 on this industry. COVID-19 can affect the global market in 3 ways: by directly affecting production and demand, by creating supply chain and market disruption, and by its financial impact on enterprises and financial markets.

This report provides detailed historical analysis of global market for Testosterone Replacement Therapy from 2014-2019, and provides extensive market forecasts from 2020-2029 by region/country and subsectors. It covers the sales volume, price, revenue, gross margin, historical growth and future perspectives in the Testosterone Replacement Therapy market.

The report provides a 6-year forecast (2020-2026) assessed based on how the Testosterone Replacement Therapy market is predicted to grow in major regions like USA, Europe, Japan, China, India, Southeast Asia, South America, South Africa, Others.

Key Questions Answered In this Report:

What is the overall market size in 2019? What will be the market growth during the forecast period i.e. 2020-2026?

Which region would have high demand for product in the upcoming years?

What are the factors driving the growth of the market?

Which sub-market will make the most significant contribution to the market?

What are the market opportunities for existing and entry-level players?

What are various long-term and short-term strategies adopted by the market players?

What are the key business strategies being adopted by new entrants in the Testosterone Replacement Therapy Market?

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Table of Contents

Market Overview: This is the first section of the report that includes an overview of the scope of products offered in the global Testosterone Replacement Therapy market, segments by product and application, and market size.

Market Competition by Player: Here, the report shows how the competition in the global Testosterone Replacement Therapy market is growing or decreasing based on deep analysis of market concentrate rate, competitive situations and trends, expansions, merger and acquisition deals, and other subjects. It also shows how different companies are progressing in the global Testosterone Replacement Therapy market in terms of revenue, production, sales, and market share.

Company Profiles and Sales Data: This part of the report is very important as it gives statistical as well as other types of analysis of leading manufacturers in the global Testosterone Replacement Therapy market. It assesses each and every player studied in the report on the basis of main business, gross margin, revenue, sales, price, competitors, manufacturing base, product specification, product application, and product category.

Market Status and Outlook by Region: The report studies the status and outlook of different regional markets such as Europe, North America, the MEA, Asia Pacific, and South America. All of the regional markets researched about in the report are examined based on price, gross margin, revenue, production, and sales. Here, the size and CAGR of the regional markets are also provided.

Market by Product: This section carefully analyzes all product segments of the global Testosterone Replacement Therapy market.

Market by Application: Here, various application segments of the global Testosterone Replacement Therapy market are taken into account for research study.

Market Forecast: It starts with revenue forecast and then continues with sales, sales growth rate, and revenue growth rate forecasts of the global Testosterone Replacement Therapy market. The forecasts are also provided taking into consideration product, application, and regional segments of the global Testosterone Replacement Therapy market.

Upstream Raw Materials: This section includes industrial chain analysis, manufacturing cost structure analysis, and key raw materials analysis of the global Testosterone Replacement Therapy market.

Marketing Strategy Analysis, Distributors: Here, the research study digs deep into behavior and other factors of downstream customers, distributors, development trends of marketing channels, and marketing channels such as indirect marketing and direct marketing.

Research Findings and Conclusion: This section is solely dedicated to the conclusion and findings of the research study on the global Testosterone Replacement Therapy market.

Appendix: This is the last section of the report that focuses on data sources, viz. primary and secondary sources, market breakdown and data triangulation, market size estimation, research programs and design, research approach and methodology, and the publishers disclaimer.

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COVID-19 impact on Testosterone Replacement Therapy Market Share, Size, Revenue, Gross Margin and Growth Rate Analysis 2020-2026

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Trending now: Testosterone Replacement Therapy Market: Business Size, Future Trends, Share and Global Analysis by Forecast: AbbVie, Endo...

Testosterone Replacement Therapy Market Sales Segmentation and Analysis by Recent Trends, Development and Growth Factors by Regions Overview to 2026 -…

Posted: June 13, 2020 at 10:52 am

Our latest research report entitle global Testosterone Replacement Therapy market provides comprehensive and deep insights into the market dynamics and growth of Global Testosterone Replacement Therapy Industry. Latest information on market risks, industry chain structure, Testosterone Replacement Therapy cost structure and opportunities are offered in this report. The entire industry is fragmented based on geographical regions, a wide range of applications and Global Testosterone Replacement Therapy Market types. The past, present and forecast market information will lead to investment feasibility by studying the crucial Global Testosterone Replacement Therapy Industry growth factors.

Global Testosterone Replacement Therapy Market Analysis By Major Players:

AbbviePfizerEli LillyTeva PharmaceuticalsMylanBayer Healthcare PharmaceuticalsAntares PharmaFerring PharmaceuticalsAllerganAntares PharmaSandozClarus TherapeuticsJuniper PharmaceuticalsEndo InternationalAcerus PharmaceuticalsForendo PharmaMetp PharmaRepros Therapeutics

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By Product Type:

GelsInjectablesPatchesOther

By End-User

HospitalsClinicsOther

Global Testosterone Replacement Therapy Market Analysis By Geographical Zones:

Europe Testosterone Replacement Therapy Market (Germany, France, Italy, Russia and UK)

North America Testosterone Replacement Therapy Market (Canada, USA and Mexico)

Latin America Testosterone Replacement Therapy Market (Middle and Africa).

Testosterone Replacement Therapy Market in Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

Asia-Pacific Testosterone Replacement Therapy Market (South-east Asia, China, India, Korea and Japan).

Global Testosterone Replacement Therapy Market news, plans & policies, market drivers, analysis of upstream raw material suppliers and downstream buyers of Testosterone Replacement Therapy is carried out in this report. On regional and country level market share, production value, gross margin analysis, consumption ratio, import-export scenario, and SWOT analysis is covered. Global Testosterone Replacement Therapy Industry forecast study enlists the market value (in USD) and volume forecast for each region, product type, and applications.

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To Provide A Clear Global Testosterone Replacement Therapy Market Structure The Report Is Divided Into 12 Chapters As Follows:

Chapter 1, states the product definition, specifications, pictures, classification and varied applications of Global Testosterone Replacement Therapy Industry;

Chapter 2, covers the price structure and Market structure covering the cost of raw materials, manufacturing cost, supplier detail of Testosterone Replacement Therapy Market;

Chapter 3, lists the technical specifications of Testosterone Replacement Therapy covering the capacity, production volume, manufacturing base, R&D status, and sources;

Chapter 4, represents the market analysis, sales channel, pricing trend, and import-export scenario of Testosterone Replacement Therapy;

Chapter 5 and 6, studies the regional presence of Global Testosterone Replacement Therapy market across North America, Europe, Asia-Pacific, Latin America, Middle East & Africa. Also, Testosterone Replacement Therapy Market analysis by Type is covered in this report;

Chapter 7 and 8, Testosterone Replacement Therapy market analysis by application and major manufacturers is covered in this report;

Chapter 9, Global and Regional Testosterone Replacement Therapy Industry trend analysis by different applications and product types is mentioned in this chapter;

Chapter 10, Enlist the regional and international Testosterone Replacement Therapy import-export scenario, utilization ratio, and supply chain analysis;

Chapter 11, The consumer analysis is covered in this chapter;

Chapter 12, presents the key research findings, conclusion, analyst views, data sources, and in-depth research methodology;

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Major points from Table of Contents for Global Testosterone Replacement Therapy Industry 2020 Market Research Report include:

1 Testosterone Replacement Therapy Market Overview

2 Global Testosterone Replacement Therapy Market Competition by Manufacturers

3 Global Testosterone Replacement Therapy Capacity, Production, Revenue (Value) by Region (2020-2026)

4 Global Testosterone Replacement Therapy Industry Supply (Production), Consumption, Export, Import by Region (2020-2026)

5 Global Testosterone Replacement Therapy Production, Revenue (Value), Price Trend by Type

6 Global Testosterone Replacement Therapy Market Analysis by Application

7 Global Testosterone Replacement Therapy Industry Manufacturers Profiles/Analysis

8 Testosterone Replacement Therapy Manufacturing Cost Analysis

9 Industrial Chain, Sourcing Strategy and Downstream Buyers

10 Marketing Strategy Analysis, Distributors/Traders

11 Market Effect Factors Analysis

12 Global Testosterone Replacement Therapy Market Forecast (2020-2026)

13 Research Findings and Conclusion

14 Appendix

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Testosterone Replacement Therapy Market Sales Segmentation and Analysis by Recent Trends, Development and Growth Factors by Regions Overview to 2026 -...

Hormone Replacement Therapy Market Outlook By Industry Size, Share, Revenue, Regions And Top Key Players Analysis From 2020-2029 – Jewish Life News

Posted: June 13, 2020 at 10:52 am

The research study on Global Hormone Replacement Therapy market 2019 presents an extensive analysis of current Hormone Replacement Therapy market size, drivers, trends, opportunities, challenges, as well as key Hormone Replacement Therapy market segments. Further, it explains various definitions and classification of the Hormone Replacement Therapy industry, applications, and chain structure.In continuation of this data, the Hormone Replacement Therapy report covers various marketing strategies followed by key players and distributors. Also explains Hormone Replacement Therapy marketing channels, potential buyers and development history. The intent of global Hormone Replacement Therapy research report is to depict the information to the user regarding Hormone Replacement Therapy market forecast and dynamics for the upcoming years. The Hormone Replacement Therapy study lists the essential elements which influence the growth of Hormone Replacement Therapy industry. Long-term evaluation of the worldwide Hormone Replacement Therapy market share from diverse countries and regions is roofed within the Hormone Replacement Therapy report. Additionally, includes Hormone Replacement Therapy type wise and application wise consumption figures.

The Final Report will cover the impact analysis of COVID-19 on this industry.

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After the basic information, the global Hormone Replacement Therapy Market study sheds light on the Hormone Replacement Therapy technological evolution, tie-ups, acquisition, innovative Hormone Replacement Therapy business approach, new launches and Hormone Replacement Therapy revenue. In addition, the Hormone Replacement Therapy industry growth in distinct regions and Hormone Replacement Therapy R;D status are enclosed within the report.The Hormone Replacement Therapy study also incorporates new investment feasibility analysis of Hormone Replacement Therapy. Together with strategically analyzing the key micro markets, the report also focuses on industry-specific drivers, restraints, opportunities, and challenges in the Hormone Replacement Therapy market.

View Source of RelatedReports :

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Global Hormone Replacement Therapy Market Segmentation 2019: Hormone Replacement TherapyThe study also classifies the entire Hormone Replacement Therapy market on basis of leading manufacturers, different types, various applications and diverse geographical regions. Overall Hormone Replacement Therapy market is characterized by the existence of well-known global and regional Hormone Replacement Therapy vendors. These established Hormone Replacement Therapy players have huge essential resources and funds for Hormone Replacement Therapy research as well as developmental activities. Also, the Hormone Replacement Therapy manufacturers focusing on the development of new Hormone Replacement Therapy technologies and feedstock. In fact, this will enhance the competitive scenario of the Hormone Replacement Therapy industry.

The Leading Players involved in global Hormone Replacement Therapy market are:

By Therapy Type (Human Growth Hormone (HGH) Replacement Therapy, Testosterone Replacement Therapy, Thyroid Replacement Therapy, Estrogen Replacement Therapy)

By Application (Growth Hormone Deficiency,Menopause, Hypothyroidism, Male Hypogonadism, and Others)

By Route of Administration (Oral, Parenteral, and Others)

By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies) 

By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa )

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Worldwide Hormone Replacement Therapy Market Different Analysis:Competitors Review of Hormone Replacement Therapy Market: Report presents the competitive landscape scenario seen among top Hormone Replacement Therapy players, their company profile, revenue, sales, business tactics and forecast Hormone Replacement Therapy industry situations. Production Review of Hormone Replacement Therapy Market: It illustrates the production volume, capacity with respect to major Hormone Replacement Therapy regions, application, type, and the price. Sales Margin and Revenue Accumulation Review of Hormone Replacement Therapy Market: Eventually explains sales margin and revenue accumulation based on key regions, price, revenue, and Hormone Replacement Therapy target consumer. Supply and Demand Review of Hormone Replacement Therapy Market: Coupled with sales margin, the report depicts the supply and demand seen in major regions, among key players and for every Hormone Replacement Therapy product type. Also interprets the Hormone Replacement Therapy import/export scenario. Other key reviews of Hormone Replacement Therapy Market: Apart from the above information, correspondingly covers the company website, number of employees, contact details of major Hormone Replacement Therapy players, potential consumers and suppliers. Also, the strengths, opportunities, Hormone Replacement Therapy market driving forces and market restraints are studied in this report.

Highlights of Global Hormone Replacement Therapy Market Report:* This report provides in detail analysis of the Hormone Replacement Therapy and provides market size (US$ Million) and Cumulative Annual Growth Rate (CAGR (%)) for the forecast period: 2019 ; 2029. * It also elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for world Hormone Replacement Therapy market. * This study also provides key insights about Hormone Replacement Therapy market drivers, restraints, opportunities, new product launches, approvals, regional outlook, and competitive strategies adopted by the leading Hormone Replacement Therapy players. * It profiles leading players in the worldwide Hormone Replacement Therapy market based on the following parameters ; company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies and future plans. * Insights from Hormone Replacement Therapy report would allow marketers and management authorities of companies to make an informed decision with respect to their future product launches, market expansion, and Hormone Replacement Therapy marketing tactics. * The world Hormone Replacement Therapy industry report caters to various stakeholders in Hormone Replacement Therapy market. That includes investors, device manufacturers, distributors and suppliers for Hormone Replacement Therapy equipment. Especially incorporates government organizations, Hormone Replacement Therapy research and consulting firms, new entrants, and financial analysts. *Various strategy matrices used in analyzing the Hormone Replacement Therapy market would provide stakeholders vital inputs to make strategic decisions accordingly.

Global Hormone Replacement Therapy Market Report Provides Comprehensive Analysis of Following: ; Hormone Replacement Therapy Market segments and sub-segments ; Industry size ; Hormone Replacement Therapy shares ; Hormone Replacement Therapy Market trends and dynamics ; Market Drivers and Hormone Replacement Therapy Opportunities ; Supply and demand of world Hormone Replacement Therapy industry ; Technological inventions in Hormone Replacement Therapy trade ; Hormone Replacement Therapy Marketing Channel Development Trend ; Global Hormone Replacement Therapy Industry Positioning ; Pricing and Brand Strategy ; Distributors/Traders List enclosed in Positioning Hormone Replacement Therapy Market.

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Moreover, the report organizes to provide essential information on current and future Hormone Replacement Therapy market movements, organizational needs and Hormone Replacement Therapy industrial innovations. Additionally, the complete Hormone Replacement Therapy report helps the new aspirants to inspect the forthcoming opportunities in the Hormone Replacement Therapy industry. Investors will get a clear idea of the dominant Hormone Replacement Therapy players and their future forecasts.

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Hormone Replacement Therapy Market Outlook By Industry Size, Share, Revenue, Regions And Top Key Players Analysis From 2020-2029 - Jewish Life News

Why one-size-fits-all diets don’t work new study – The Conversation UK

Posted: June 13, 2020 at 10:51 am

The coronavirus pandemic has pushed health to the forefront of many peoples minds. And while the best way to avoid COVID-19 is not to catch the virus in the first place, were starting to understand why some people become seriously ill with the disease while others have only mild or no symptoms.

Age and frailty are the most important risk factors for severe COVID-19, but data from our COVID Symptom Study app, used by nearly four million people, has shown that diet-related conditions, such as obesity, heart disease and type 2 diabetes, are significant risk factors for ending up in hospital with the disease.

In the UK, around one in three adults are obese and many more are overweight. In the US, around two in five adults and nearly one in five children are obese. From generalised government nutritional guidelines to Instagram-worthy fad diets, theres no end of advice on how to lose weight. Clearly, it isnt working.

This is a complex problem to unpick. Factors such as sex, ethnicity, socioeconomic status and availability of healthy food all play a part. But on an individual level, we still understand relatively little about how each person should eat to optimise their health and weight.

In search of answers, our research team at Kings College London together with our colleagues at Massachusetts General Hospital, Stanford University and health science company ZOE launched PREDICT, the largest ongoing nutritional study of its kind in the world. Our first results have now been published in Nature Medicine.

PREDICT-1, the first phase of the PREDICT research programme, involved more than 1,000 adults (including hundreds of pairs of twins) who were continuously monitored for two weeks to discover how they respond to different foods.

Participants had an initial set-up day in hospital for detailed blood measurements and testing of responses after eating carefully designed set meals. They then carried out the rest of the study at home, following a schedule of set meals and their own free choice of foods. We measured a wide range of markers of nutritional responses and health from blood glucose, fat, insulin and inflammation levels to exercise, sleep and gut bacteria (microbiome) diversity.

This kind of detailed, ongoing analysis was made possible through the use of wearable technologies. These included continuous blood glucose monitors and digital activity trackers, which meant we could keep track of our participants blood sugar and activity levels 24/7. Simple finger-prick blood tests also allowed us to measure their blood fat levels on a regular basis.

All these measurements added up to millions of datapoints, which needed to be analysed with sophisticated machine learning techniques (a type of artificial intelligence) in order to spot patterns and make predictions.

The first thing we noticed was the wide variation in individual insulin, blood sugar and blood fat responses to the same meals, even for identical twins. For example, one twin might have healthy responses to eating carbohydrates but not fat, while the other twin is the opposite. Straight away, this tells us that we are all unique and that there is no perfect diet or correct way to eat that will work for everyone.

The observation that genetics only plays a minor role in determining how we respond to food also tells us that simple genetic tests claiming to determine the right diet for your genes are ineffective and misleading. Curiously, identical twins only shared around a third of the same gut microbe species, which may help to explain some of the variation in nutritional responses and also points towards an opportunity to improve health and weight by manipulating the microbiome.

We also discovered that the timing of meals affects nutritional responses in a personalised way. The same meal at breakfast caused a different nutritional response in some people when eaten for lunch. But in other people there was no difference, busting the myth that there are correct mealtimes that will work for all.

Another surprise was finding that the composition of meals in terms of calories, fat, carbohydrates, proteins and fibre (macronutrients or macros) also had a highly individualised effect on nutritional responses. Some people handle carbs better than fat, for example, while others have the opposite response. So prescriptive diets based on fixed calorie counts or macronutrient ratios are too simplistic and will not work for everyone.

However, despite the wide variability between participants, each persons own responses to identical meals eaten at the same times on different days were remarkably consistent. This makes it possible to predict how someone might respond to any food based on knowledge of their underlying metabolism.

Intriguingly, we found that the levels of inflammatory molecules in the blood varied by up to tenfold, even in seemingly healthy people, and that a rise in these inflammation markers was linked to having unhealthy responses to fat.

We use the term dietary inflammation to refer to these unhealthy metabolic effects that are triggered after eating. Repeatedly experiencing dietary inflammation brought on by excessive blood sugar and fat responses is linked with an increased risk of conditions such as heart disease, type 2 diabetes, non-alcoholic fatty liver disease and obesity.

On a more positive note, our findings suggest that it might be possible to improve weight management and long-term health by eating in a more personalised way designed to avoid triggering unhealthy inflammatory responses after meals.

When it comes to weight, weve traditionally put a huge emphasis on factors we have no control over, especially genetics. The fact is, while genetics plays a role, many more important factors affect how our metabolism, weight and health. Its time to move away from overly generalised guidelines, fad diets and one-size-fits-all plans and develop more personalised, scientific approaches to nutrition that understand and work together with our bodies, not against them.

For more on personalised nutrition, download and listen to our podcast, Medicine made for you, a series by The Anthill.

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Why one-size-fits-all diets don't work new study - The Conversation UK

Why it’s so difficult to lose weight: The hard truths – CNET

Posted: June 13, 2020 at 10:51 am

Weight loss is hard. It's even tougher when you fall victim to these hard truths.

Why is it so hard to lose weight? It's a question many, if not most, people have asked themselves, probably on many occasions. Aside from the obvious -- food is delicious, exerciseis hard and time is short -- there are many other factors that affect weight loss and that many people don't even know they fall victim to. Here are six that might be hindering your weight loss progress.

Instead of embarking on fad diet after fad diet, take a long-term approach to weight loss.

Everything on this list is somewhat of a hard truth, but this is often the hardest to accept (and change). If you approach weight loss with a short-term attitude, you may not make it anywhere except on the yo-yo diet train.

Without a long-term approach to weight loss, you may end up losing 10 or more pounds in two weeks and then suffer a rebound when you discover that regimen wasn't working for you. This is all too common when people embark on strict diets such as keto or paleo, or fad diets that promise rapid weight loss. In reality, for most people, a well-balanced diet that includes all food groups and even some treats works best in the long run.

Part of successful, sustainable weight loss -- i.e. losing the weight and keeping it off for good -- is understanding that fad diets, excessive exercise and "detoxes" don't usually work. They only last as long as your willpower lasts, and I'm willing to bet that's not more than two weeks to a couple of months.

There are no quick fixes, miracle cures or magic pills when it comes to weight loss, despite what the wellness industry might have you believe: Losing weight requires dedication to a plan that supports long-term healthy habits.

The general recommendation for weight loss is a rate of one to two pounds per week, although initial weight loss might surpass that for people who are very overweight, and then slow down to the suggested one to two pounds per week. Studies have shown this to be an effective way to lose weight without losing too much water or lean tissue -- and to avoid a rebound.

Overcoming an all-or-nothing mindset promotes long-term weight loss.

Many people who struggle with a short-term attitude also struggle with an all-or-nothing mindset. I myself began my health and fitness journey with this mindset. I cut out all (literally all!) processed foods: no bread, no pasta, no milk, no cheese, definitely no individually wrapped snacks. I basically existed on chicken, vegetables and berries.

This was great until it wasn't, and I ended up on a CVS run for all the chocolate and Goldfish I could hold in two hands. Then, because I'd "ruined" my diet, I would eat as much as I could physically handle, because, "Why not? I already ruined it."

Then, of course, I'd feel bad about the snacks I ate and return to my overly restrictive regimen the next day. This is a destructive cycle to be in, but it's something I see all the time as a personal trainer. An all-or-nothing mindset can keep you in a perpetual cycle of lose-gain-lose, not to mention shame and guilt around food.

This all-or-nothing concept applies to fitness, too: If you've been crushing workouts left and right but don't feel fitter or stronger, you might be doing too much. Toning it down could -- counterintuitively -- be the answer to improving your fitness (and playing the long game).

A supportive community, IRL or online, can keep you motivated to lose weight and stay fit.

Supportive friends, family members and significant others are critical to successful weight loss. If I was asked to cite the most common reason for not sticking to a healthy diet from my past personal training clients, I would say stigma.

That's right. As silly as it sounds, people really do get made fun of for eating healthy, especially in regions where food is an integral part of the culture. Growing up in southern Louisiana near New Orleans, I experienced this very often when I decided I was making changes to my diet.

At family gatherings and social outings, I'd get comments like, "That's all you're eating?" or, "You're really not going to eat any dessert?" or, laden with sarcasm, "Next time we'll have a salad potluck."

It's not fun to be ridiculed or scoffed at, especially for things you care about (like your health!), so it can be very easy to fall into a trap of eating -- and drinking -- for the sake of your social life. This is why a solid support system is key to long-term weight loss. Without it, the journey can feel lonely and intimidating.

If you currently feel you lack a support system, try having open conversations with your friends, family and partner about it. You can make it clear that they don't have to change their eating habits if they don't want to, but that your health means a lot to you and you'd appreciate it if they didn't mock or downplay your hard work.

If an IRL support system isn't working out, turn to online communities that promote both health and body positivity. I really love Fit Approach on Instagram, Health At Every Size and the Intuitive Eating Community. Reddit also has a great forum (/r/loseit) where you'll find lots of real-life stories about weight loss.

Exercise is important for an overall healthy lifestyle, but it's hard to lose weight from exercise alone.

If you're at all attuned to the wellness industry, you'll know this saying: "Abs are made in the kitchen, not the gym." Even if your goals don't include a shredded stomach, the adage is still relevant. You just can't out-exercise a poor diet.

Exercise should definitely be part of your overall approach to weight loss because it's proven to aid weight loss (not to mention its long list of other health benefits), but it's difficult to lose weight from exercise alone. Many people overestimate the number of calories they can burn from their workouts -- it's probably a lot less than you think.

For example, a 154-pound man will burn less than 450 calories during an intense, hour-long weight lifting workout. You can easily cancel that effort out if you don't pay any attention to your diet. The exact number of calories you burn during exercise depends on many factors, including your current weight, the intensity of the activity, the length of the workout, your age and your body composition.

Plus, focusing on only exercise can lead to a destructive cycle of exercising extra to burn off calories you feel you shouldn't have eaten. Or you may end up feeling like you need to "earn" your calories through exercise. Either way, taking this approach can lead to a strained relationship with food and exercise, as well as stalled weight loss.

There are exceptions to all rules. Some people, such as those who have spent years putting on muscle mass, can eat lots of calorie-dense food and not gain weight -- but even if you can eat whatever you want and lose or maintain your weight, that doesn't mean it's healthy for you.

A diet rich in fruit, vegetables, healthy fats, lean proteins and some whole grains will serve you best in terms of sustainable weight loss and health. Combined with a consistent exercise routine, you'll experience sustained weight loss and weight maintenance once you reach your goal weight.

Chronic stress and sleep deprivation can hinder weight loss progress.

Losing weight will be a helluva lot harder if you're chronically stressed, sleep-deprived or overworked. This scenario may sound familiar to you:

This is OK if it happens occasionally (everyone deserves a lazy evening every once in a while), but weight loss will seem impossible if this happens all the time.

The truth is, nutrition and exercise are only two components of a healthy life that can lead to weight loss. While important, too strong of a focus on nutrition and exercise can cause you to overlook other factors that are just as important: sleep and stress management.

Supplements don't work unless you do.

I hate to be the bearer of bad news, but that fat burner supplement in your medicine cabinet isn't going to do the work for you. While certain supplements may help you reach your weight loss goals, you have to work to make your supplements work.

For example, incorporating a daily protein shake in the mornings can help you feel fuller throughout the day, which may help keep cravings at bay. Increased protein intake can also help you build muscle, which aids in body recomposition.

Certain weight-loss supplements do have some evidence backing them, but no supplements are proven like the method that no one wants to take: eat fewer calories than you burn.

The information contained in this article is for educational and informational purposes only and is not intended as health or medical advice. Always consult a physician or other qualified health provider regarding any questions you may have about a medical condition or health objectives.

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Why it's so difficult to lose weight: The hard truths - CNET

Role of exercise and diet in weight loss – Can one work without the other? – Times Now

Posted: June 13, 2020 at 10:51 am

Role of exercise and diet in weight loss - Can one work without the other?  |  Photo Credit: iStock Images

New Delhi: We all know that exercise and diet play an important role in helping us lose weight and getting in shape. While a balanced diet and regular physical activity are both equally important to live a healthy, long life, when it comes to weight loss, one may have more effect on our weight, than the other. While some people rely on vigorous exercise to lose weight, others follow a strict diet. However, people who follow an exercise routine may also supplement it with a healthy diet, and for those who follow a strict diet, may also some form of physical activity in your routine.

But what happens when you do not? What happens to your body and the weight loss process, if you rely only on one of these key measures to lose weight? Let's find out.

If you are trying to lose weight, the diet maybe even more important than exercise. While exercise ensures that your muscles and body are able to use up the food you eat, it is a diet that ensures weight loss in an actual way. How many calories you consume, and the nutrients in your food determine the spare calories left unutilised at the end of the day, and the efficiency of your body functions. If you eat very high-calorie food or food that contains a lot of sugar, you are not likely to lose weight. At the same time, you also have to watch the intake of the various nutrients including fibre and protein for a healthy weight loss.

Exercise also plays an important role in weight loss. It is, in fact, extremely important to exercise if you are not on a strict diet, as exercise can help you burn the extra calories you consume. More than for weight loss, exercise is important to build strength in your body, and make your muscles and bones strong. Exercise also helps to tone your body and distribute fat equally at all places on your body.

Disclaimer: Tips and suggestions mentioned in the article are for general information purposes only and should not be construed as professional medical advice. Always consult your doctor or a professional healthcare provider if you have any specific questions about any medical matter.

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Role of exercise and diet in weight loss - Can one work without the other? - Times Now


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