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Bill Turnbull reveals healthy diet and meditation are helping him battle cancer amid mood swings from hormone – The Sun

Posted: March 29, 2020 at 8:44 pm

BILL Turnbull has revealed how his new diet has made him feel more healthy as he battles cancer.

The news presenter was diagnosed with incurable prostate cancer in 2017, and also said hormone treatment has left him experiencing mood swings.

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Bill, 64, explained: "Most of the time, I am absolutely fine, I get hot flushes, they pass. But occasionally, I can feel my mood THREAT doorstep dipping.

"Now when we go down into a dip and I howl like a baby - well, like a grown man, which is much worse - I understand it is chemically induced and it will pass the next day. And it always does.

"At the moment, we are holding steady. I'm on a treatment called Radium 223. It was working very well for five months, now it is working sort of OK."

The telly favourite says lifestyle changes such as removing meat and dairy from his diet and taking up yoga and meditation have left him feeling healthier.

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And putting his career skills to good use, he conducted some research on plant-based diets.

The journalist told The Mirror: "I did a lot of research and it comes up time and time again that a wholefood, plant-based diet is good for you. It gets overwhelming, but it is great to be part of that cancer family.

"You get a lot of support from other people."

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FEELING BROODYStacey hints she could get pregnant again soon as she lusts over Joe Swash

baby can i hold youRonan Keating reveals wife Storm has given birth to their second child

'HELLO, LEGS OPEN!'Michelle Keegan almost flashes fans in Instagram chat with Olly Murs

NOT OUR GIRLDani Dyer cried during audition for Our Girl before Michelle Keegan won role

family completeJames and Ola Jordan finally share their baby daughter's name with fans

'where's storm?'Jac and Dan Osborne confuse fans with 'new puppies' in sweet family photo

Just last month, Bill temporarily returned to presenting duties as he reunited with Susanna Reid six years after they fronted BBC breakfast together.

However, the show, which took place on a Wednesday descended into chaos when he lost his earpiece in the ad break and Susanna mocked her co-presenter as she joked: "You know that they call Wednesday hump day. Bill is really having one of those Wednesdays."

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Bill Turnbull reveals healthy diet and meditation are helping him battle cancer amid mood swings from hormone - The Sun

Easy recipes to boost your mood during coronavirus lockdown – The Sun

Posted: March 29, 2020 at 8:44 pm

A HEALTHY diet is about far more than losing weight, and as coronavirus forces millions of people to lock themselves away from the world, it could prove invaluable for our mental health too.

While good nutrition has long been linked to a healthier mindset, experts have now revealed the simple act of cooking can make us happier too - offering a much-needed distraction and group activity inside.

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"Cooking can benefit our mental health because it is a mindful activity - right the way from meal prep to making the actual dish," says Dr Elena Touroni, a consultant psychologist and co-founder of The Chelsea Psychology Clinic.

"Provided were not on autopilot, when were cooking were free from distraction and fully engaged in what were doing."

Dr Clare Bailey, wife of TV favourite Dr Michael Mosleys, tells Sun Online that a healthy diet can dramatically reduce stress levels and even help with sleeplessness.

"The link lies in our gut. Eighty per cent of our serotonin - our happy hormone - is produced in the gut, so the healthier the gut the more emotionally resilient we are," she explains.

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Essentially she says the more relaxed and happy you're feeling, the more likely you are to enjoy a deep sleep - and in turn improve your bodys ability to fight infection.

Mental health charities have reported a surge in calls to their helplines and many people are feeling panicked by the financial insecurity, loneliness and uncertainty brought on by coronavirus and lockdown.

That's why The Sun's You're Not Alone campaign has launched a series to raise awareness of the pandemic's effect on mental wellbeing.

"Baking is a great activity to keep the kids busy and put smiles on their faces - and it's good therapy for stressed-out grown-ups, too," says baker Sarah Rainey.

Here, chefs share their recipes and tips for cheap and easy meals - from one pot wonders to three-ingredient cakes:

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(Serves 8-10)

YOU NEED

METHOD:

Preheat the oven to 200C (fan 180C) and grease and line a standard 2lb loaf tin with a little butter and greaseproof paper.

Sift the flour into a mixing bowl, and add the sugar followed by the beer. Pour the beer in gradually so it doesnt froth too much.

Mix everything together using a wooden spoon and transfer the dough to the tin.

Dust the top with a little flour before putting it in the oven. Bake the loaf for 45-50 minutes. Youll know its done when the crust on top turns golden (and you can stick a skewer down the centre of the loaf to check the inside is cooked through).

Turn it out onto a wire rack to cool.

If you cant get your hands on a dark beer, pale ale will do just fine or you could even use a can of low-sugar lemonade for a slightly sweet-slightly salted loaf that goes well with cheese.

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(Serves 2)

YOU NEED:

METHOD:

Heat the olive oil in a large frying pan over a low-medium heat. Once warm, add the garlic, fry until starting to turn golden, then add the spices and cook for a further 30 seconds.

Tip in the plum tomatoes, Worcestershire sauce, sugar, vinegar and cannellini beans. Season, bring to the boil, then simmer on a medium-high heat for 1520 minutes until slightly thickened.

Toast your bread and serve piled high with the beans, topped with a fried egg, if you like.

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(Makes 1 portion - 4 lettuce tacos)

YOU NEED:

METHOD:

Coat the chicken thigh in a mixture of paprika, a pinch of salt and pepper and a drizzle of olive oil.

Pan-fry the chicken over a low-medium heat, skin-side down first, for 1012 minutes on each side until cooked through and caramelised on the outside.

Remove from the heat and set the chicken to one side.

Add the couscous to the pan (off the heat), along with the water, and stir for a few seconds to incorporate all the pan juices, then leave the couscous to rest for a few minutes and plump up.

Slice the chicken into thin strips, then assemble your tacos by spooning some of the peri peri-infused couscous onto each lettuce leaf, placing some chicken strips on top, then drizzling with the yogurt and sprinkling over some cracked black pepper.

Super Easy One Pound Meals by Miguel Barclays (8.95, Headline).

Nutritional tips for a good gut

There's no set rule when it comes to choosing what you eat each day, but Dr Bailey has shared a few simple diet tips to boost gut health and your ability to cope with stress:

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(Serves 2)

YOU NEED:

METHOD:

Preheat your oven to 180C/gas mark 6.

On a large baking tray, toss together the squash, chilli flakes, fennel and cumin seeds, cinnamon, garlic and oil, then season and roast for 20 minutes, or until the squash is starting to turn golden and soft but still holding its shape.

Toss the chickpeas through and roast in the oven for a further 10 minutes.

Meanwhile, boil the pasta in salted water according to pack instructions or until tender, reserve a mug of the cooking water, then drain.

Using a potato masher, roughly crush about half the butternut squash and chickpea mixture. Add the pasta, yogurt, parsley and enough of the reserved cooking water to the tray to coat the pasta in the sauce. Adjust the seasoning, top with the breadcrumb mixture and serve.

Take One Tin by Lola Milne (Kyle Books, 14.99). Photography by Lizzie Mayson.

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(Serves 4-6)

Preparation time: 15 minutes

Cooking time: (Pre-cook 10 minutes) Auto-low 8 hours, or high 4 hours

YOU NEED:

METHOD:

Preheat the slow cooker, if required.

Heat the oil in a large heavy-based pan over a medium heat, add the onion, and cook for 34 minutes until soft.

Season with salt and pepper, then stir through the garlic and celery and cook for a further 5 minutes or until the celery is soft.

Stir in the carrots, tarragon, and rosemary and cook for a minute before transferring everything to the slow cooker. Stir in the pured tomatoes and stock and cook on auto/low for 8 hours or on high for 4 hours.

Add the potatoes for the last 15 minutes of cooking.

When the potatoes are soft, add the beans and cook for 10 minutes, or until they are cooked but retain a bite.

Taste and season, remove the rosemary, and ladle into warmed large shallow bowls. Sprinkle over the Parmesan, if using, and serve with some crusty French bread.

The Slow Cook Book by Heather Whinney (DK, 16.99)

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(Makes 4)

YOU NEED:

METHOD:

Preheat the oven to 190C/Fan 170C. Grease 4 small ramekins with butter or flavourless oil.

Mix one tablespoon of icing sugar into the chocolate spread. Separate the eggs and whisk the yolks into the chocolate mixture. In another bowl, whisk the whites until they form stiff peaks. Slowly fold the whites into the chocolate mixture, a little at a time, taking care not to beat out the air.

Divide between the ramekins, filling each 2/3 full. Wipe excess batter off the rims so they rise. Bake on a tray in the centre of the oven, for 15-18 minutes until fluffy and risen. Dust the remaining icing sugar over the top and serve immediately topped, if you like, with ice cream or whipped cream.

Six Minute Showstoppers by Sarah Rainey is out on May 14th. Her first book, Three Ingredient Baking, (Michael Joseph, 12.99) is available now.

You're Not Alone

EVERY 90 minutes in the UK a life is lost to suicide.

It doesn't discriminate, touching the lives of people in every corner of society - from the homeless and unemployed to builders and doctors, reality stars and footballers.

It's the biggest killer of people under the age of 35, more deadly than cancer and car crashes.

And men are three times more likely to take their own life than women.

Yet it's rarely spoken of, a taboo that threatens to continue its deadly rampage unless we all stop and take notice, now.

That is whyThe Sun launched the You're Not Alone campaign.

The aim is that by sharing practical advice, raising awareness and breaking down the barriers people face when talking about their mental health, we can all do our bit to help save lives.

Let's all vow to ask for help when we need it, and listen out for others...You're Not Alone.

If you, or anyone you know, needs help dealing with mental health problems, the following organisations provide support:

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(Serves 10)

Preparation time: 25 minutes

Bakine time: 25 minutes

YOU NEED:

METHOD:

Heat the oven to 200C/180C fan/400F/Gas 6.

Blitz the biscuits in a food processor to fine crumbs. Remove 2 tablespoons of the crumbs and set aside. Add the melted butter to the crumbs in the food processor and blitz for a few seconds more until combined.

Transfer the buttery biscuit mixture to the prepared tin and use the back of a spoon to press it down firmly and evenly all the way to the edges of the tin to give an even base.

Place the egg yolks in a medium bowl. Using a balloon whisk, whisk in the condensed milk until fully incorporated. Then, slowly whisk in the lemon juice until combined. Pour the mixture on top of the biscuit base.

Place the egg whites in a clean, grease-free bowl and whisk with an electric hand whisk to stiff peaks.

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CORONAVIRUS CRISIS - STAY IN THE KNOW

Don't miss the latest news and figures - and essential advice for you and your family.

To receive The Sun's Coronavirus newsletter in your inbox every tea time, sign up here.

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Easy recipes to boost your mood during coronavirus lockdown - The Sun

SlimVision specializes in facial rejuvenation, total body aesthetics, and body shaping/weight loss through advanced technology. (032520) – KSNF/KODE -…

Posted: March 29, 2020 at 2:48 am

Posted: Mar 28, 2020 / 09:55 PM CDT / Updated: Mar 28, 2020 / 09:55 PM CDT

AtSlimVisionWeight Loss & Laser Center we provide our clients with a multitude of treatments in our medical spas relaxing environment, where our staff of expertly trained and certified professionals will treat you with care and individualized attention. Were confident that youll be completely satisfied with your experience, and your treatment results. Employing only a professionally-trained and courteous staff ensures that our clients will receive todays safest, state-of-the-art, non-surgical cosmetic treatment procedures, specially-tailored consultations and expert advice.

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Phone: (918) 542-8477Fax: (918) 542-6422

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SlimVision specializes in facial rejuvenation, total body aesthetics, and body shaping/weight loss through advanced technology. (032520) - KSNF/KODE -...

Weight Loss and Teen Board of Directors Was on Agenda for Kristin Kreuk’s Suspicious Girls By Design – Frank Report

Posted: March 29, 2020 at 2:48 am

By MK10ART

GBD Deep Dive Pt 3

At the end of September 2008, Kristin Kreuk posted about getting together with a group of (Nxivm) ladies. She lavished praises on pregnant Kendra and her close friend Allison Mack. This group of mainly unnamed women were Nxivm cult members. Of course, the Nxivm part was omitted in Kreuks post and it was simply described as a random gathering for no reason. Kendra and Tabbys attendance also shows that they were just as involved in the Nxivm group even if they never met Keith Raniere in person.

Allison Mack was Ranieres first line DOS slave.

Posted by Kristin | Filed underFab Females

There is something special when women come together. It is such a comfortable, warm and truly inspiring experience. About 15 ladies got together last night at my place, and it was soooo beautiful. We ate, chatted, avoided stepping on the dog, and really just hung out. A lot of our time was spent introducing each other and sharing why we value and love the ladies we brought with us There were some tears. Okay, a lot of tears. haha we are such girls. I love it

So we had Kendra and her belly, which is having plenty of movement these days. K is such a fabulous lady. She has a drive and determination that is very powerful. She talks a lot about being afraid all the time, which is something I do experience with her, but I also see her taking these great chances. I mean the woman has chosen to have a baby and build this company. At the same time. That is pretty balls.

And Tabby was there as well I see Tabs as a girl who has gone through a lot of shite and has chosen to create a positive and productive life. She left her life (and kitty) in L.A. and came to Vancouver in like two daysokay slight exaggeration, but still. Tabby has a really lovely girlish energy, combo-ed with an ability to call code beautiful.

Allie-mack is one of my dearest friends. She has been an inspiration to me in her ability to be open, and to translate her passions to others in a way that they get passionate too. Allison is so great at bringing people together to create. And her commitment to help others is something that we share. I have so enjoyed spending these years of my life in her presence.

And my dear friend Rose Who to me is the embodiment of woman. She is a pillar of strength and a force of female-ness. Intelligent, holistic and ultimately compassionate I see so much of the type of woman I want to be. Rose-y is now a beautiful mother of a seven month old girl, and this seems to have brought out a vulnerability in her that I hadnt experienced before. She is truly amazing

These are just a few of the wonderful gals that were present. And I say this because I think that it would be so lovely for all of you to get a group of your girlfriends together, learn about each other, connect, share your experiences That is essentially what GBD is about: bringing females together. I believe that women have an important perspective to offer the world. Now, this isnt about the exclusion of men, its about the focus on female. With men around I think it is more challenging for girls to just be girls. But the more I embrace my female-ness, the more I can appreciate and love men and other women for that matter. So, get a few or a lot of your gal friends together, and spend time together with the focus on female-ness. And share your experience with us!!!

Love,

Kristin

Tags:friends,Girls Rule!,kristin kreuk

Permalink|September 23rd, 2008

Frank published a story about this gathering here: https://frankreport.com/2018/10/30/reader-kristin-kreuk-describes-a-womens-meeting-at-her-home-only-problem-everyone-including-allison-mack-are-nxivm/

Frank writes, Sounds like Kristin Kook is describing a JNESS meeting that took place at her house. An all-female NXIVM group. All the women she wrote about in this post: Ally Wack, Tabby Chapman, Kendra and Rose Bhura were all in NXIVM. Mack, Bhura and Kendra were recruited by Kook and Chapman was a Smallville fan recruited by Mack. And apparently, now, at least one GBD girl, Jane recruited into NXIVM by Kristin Kook started in GBD and is now a branded sex slave. If thats true, thats really bad.

And there was Kreuk and Kendra denying (lying) GBD was not related to NXIVM without confirming or denying they were NXIVM cultists. Bad, very bad. This was just two years into Kreuks NXIVM involvement. She had already leveraged her fame to recruit for NXIVM through Acapella Innovations, College Project, Juicy Peach, and GBD. She was four years away from being named in Joe OHaras lawsuit as a likely future defendant. In two years time, she would be on Necker Island for a secret NXIVM cult summit where money laundering was said to of been planned.

Kreuk and Kendra claim that their activities with GBD had nothing to do with Nxivm and was completely innocent. Then why did Kreuk feel the need to hide the nature of her group of friends? If Kreuk and Kendra were doing nothing wrong, then why not bring up the empowerment group for women called Jness? (Even though we know now that it was really a misogynist group taught by Raniere.) Still, if Kreuk and Kendra were so innocent, why the secrecy? This writer believes that Kreuk and Kendra knew exactly what they were doing with GBD recruiting teens into Nxivm and they were under instruction to keep that hidden from GBD by Keith Raniere.

***

October 2008 started with more demands from the Smallville diva. She wanted some creations from the teenagers to compete for a spot on a GBD Teen Board of Directors.

Kreuk did not give any directions on what the teens should submit to compete. Naturally, this left the teens confused. When some of the teenagers asked for clarification, Kreuk was dismissive and gave nothing more than Do what you are inspired to do. Judging by the lack of comments to this (and other) posts, it seems most were inspired to do nothing. After all, they had homework to do.

Posted by Kristin | Filed underFab Females,General Blog

Just reminding you ladies that Oct. 1st is the final date for submissions for the GBD Teen Board of Directors!!! So send in your creations. Anything that shows why you would be great for the position! I am getting a lot of feedback re: the vague-ness of the submission request. There is no right or wrong way, just do what you are inspired to do! In our education system, things are so rule-bound and specific, I think that this really open request encourages a more true expression. Try not to think too much about what we want, cuz we arent looking for specifics, we are looking at your creations.

Thank you to those of you who have already submitted, beautiful work darlings!

xoxo

Kristin

***

The vagueness of Kristins requests sounds suspiciously similar to the directions (or lack thereof) that Raniere gave to Dani when she was locked in a room for 700 days. In Lauren Salzmans trial testimony she stated that Keith told her that in dealing with Dani, you do not want to tell her what to do or how to be. In other words, Dani was supposed to stay in the room until she figured out how to fix things without any directions from Keith. Dani didnt know what to say or do to get out. All she knew was that it was Keiths decision.

Keith would not tell her what to do but tell her to figure it out herself. Over and over Dani would write and write to no avail. Whatever she did wasnt good enough and she had no idea why. It was a complete mindf*ck by the psychopath Keith Raniere.

This same figure it out for yourself speech was now being sputtered by Kreuk to the GBD girls. Kreuk tells them to create something to compete for a board position but she wont give the any directions on what to create to compete. This complete lack of direction has Raniere written all over it. He probably chose the winners.

One reason for the lack of instructions could have been that it would allow Keith & Co. to pick whoever they wanted for the winners. The other applicants wouldnt know why the winner was chosen since all of the submissions would be completely different. With no clear indication as to whose submission was better than the others then, in theory, anyone could win. Anyone Keith chose.

Another reason for the lack of directions might have been because Kreuk had already requested videos of the girls multiple times (without much success apparently.) This open ended request for a creation of some kind seems to be another request for videos/pictures of the girls without openly saying it, which might look suspicious at this point. Keith would have understood that.

The whole idea of a teen board of directors for a website is suspicious in itself. GBD was only 3 months old at this point and wasnt involved in anything requiring a board of any kind. It appears the whole thing may have been a ruse to obtain more videos of the girls.

In other GBD news, also at the end of September, Tabby is having trouble sticking to her diet and asks for tips from the teenagers. Again, they made sure to reiterate the weight loss agenda that Keith believes in so strongly for young women.

Posted by Tabby | Filed underJourney

*Crickets chirp*

*another round of chirping*

Um hi guys! So! Its been a while since I updated you all on my journey. The journey turned more into an extended stop at the inn on the outskirts of town with lots of meat and mead. So, the update is that there is no changes in my weight lately because I havent attempted to loose it. I went back to a hybrid of my old eating style and my new eating style (which really means Subway Wraps for lunch and Romanos Macorni Grill for dinner). I dont really know why, at this point, I made that choice with the exception that Ive been away from home on an extended trip and I could pretty much get away with eating whatever I wanted. That and I injured my hip recently so I havent been able to get in any physical activity.

Do you guys ever experience that? What do you typically do to get over that hump?

xotabby

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Weight Loss and Teen Board of Directors Was on Agenda for Kristin Kreuk's Suspicious Girls By Design - Frank Report

Here’s how you can make chai masala at home that boosts immunity and aids weight loss – PINKVILLA

Posted: March 29, 2020 at 2:48 am

Masala not only adds flavour to the tea, but it is also great for the immunity. Read below to find out how you can this chai masala at home with all the available spices.

In India, usually, everyone begins their day with a hot cup of tea. Chai is not just a beverage for us, it is much more than that. Chai is a part of our morning ritual, and we cannot miss out on it by any means. However, when it comes to making a cup of tea, we add a lot more to it than just the basic tea powder and sugar. We add some masalas that only add more flavour to the tea, but also helps to improve our health in multiple ways. And hence, with that, the concept of masala chai is getting popular with time.

As you know we are under complete lockdown for a few days, so you can make the masala at home since it helps you build strong immunity. If you love chai, then here's the masala recipe that'll not only make you tea taste better but will make you strong, and will further aid weight loss.

Here are the ingredients you need:

To make this chai masala, you need to have 2 tbsp of green cardamom, 1 tbsp cloves, 2 tbsp black pepper, 3-4 sticks cinnamon and cup dry ginger powder. All these ingredients are known for their antibacterial and anti-inflammatory properties that help boost the immunity of the body during weather change. These Indian spices also keep the body warm and also provides you with much-needed energy. They promote digestion and furthermore aid weight loss.

Here's how you can make chai masala:

Before starting out, it is advisable to keep all the ingredients under the sun for at least 15 minutes. Post that, take a grinder jar and add all the ingredients into it. Grind them together to make a fine powder. Allow it to cool down and fill in an airtight glass container. And that's it your chai masala is ready. Add a pinch of it to your regular chai and stay healthy!

All these masalas, when blended together, provide a great number of antioxidants that help aid the immune system in fighting off oxidative damage and free radicals.

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Here's how you can make chai masala at home that boosts immunity and aids weight loss - PINKVILLA

Esperion Announces Three Data Presentations of the NEXLETOL (bempedoic acid) Tablet and the NEXLIZET (bempedoic acid and ezetimibe) Tablet at the…

Posted: March 29, 2020 at 2:47 am

ANN ARBOR, Mich., March 28, 2020 (GLOBE NEWSWIRE) -- Esperion (NASDAQ:ESPR) today announced that two pooled analyses from four Phase 3 clinical trials of NEXLETOL and results from the Phase 2 (1002-058) study of NEXLIZET were presented at the American College of Cardiologys 69th Scientific Session Together with World Congress of Cardiology (ACC.20/WCC).

A poster titled Bempedoic Acid 180 mg + Ezetimibe 10 mg Fixed Combination Drug Product vs Ezetimibe Alone or Placebo in Patients with Type 2 Diabetes and Hypercholesterolemia was presented by Harold E Bays, MD, FOMA, FTOS, FACC, FACE, FNLA. The poster highlighted that in the Phase 2 (1002-058) study, NEXLIZET significantly lowered LDL-Cholesterol (LDL-C) by a mean 40% compared to placebo, reduced high-sensitivity C-reactive protein (hsCRP) by 25% compared to baseline and resulted in no worsening of glycemic control. The incidence of adverse events rates were generally comparable to placebo.

In addition, a poster, titled Factors Influencing Bempedoic AcidMediated Reductions in High-sensitivity C-reactive Protein: Analysis of Pooled Patient-level Data from 4 Phase 3 Clinical Trials was presented by Eric S. G. Stroes, MD, PhD. The poster highlighted that in the pooled Phase 3 studies, NEXLETOL significantly lowered hsCRP in patients with hypercholesterolemia regardless of the presence or intensity of background statin therapy. In patients whose hsCRP levels were >2 mg/L at baseline, the analysis showed NEXLETOL significantly reduced this marker of inflammation by 42% at 12 weeks.

The third poster, titled Bempedoic Acid Efficacy and Safety in Patients at High Risk for CVD Treated with or Without Ezetimibe: Pooled Analysis of 4 Phase 3 Clinical Trials was presented by Maciej Banach, MD, PhD, FAHA, FESC. The pooled analysis showed that in the Phase 3 studies, NEXLETOL provided significant additional LDL-C lowering as well as significantly lowered other lipid (total cholesterol, non-HDL-C Apo B, HDL-C) endpoints, regardless of the presence of background ezetimibe. Importantly, the safety profile of NEXLETOL was similar with or without background ezetimibe therapy.

We are pleased with the final results of the Phase 2 study that highlight NEXLIZET achieved an impressive 40 percent LDL-C lowering, a significant 25 percent reduction in hsCRP and did not worsen glycemic control in patients with Type 2 diabetes. The additional pooled analyses from the Phase 3 LDL-C lowering development program demonstrate NEXLETOL can be safely added to multiple LDL-C medicines, which is important to help more patients reach their LDL-C goals, said Tim Mayleben, president and chief executive officer of Esperion. These additional analyses further affirm the efficacy and safety of our medicines for the millions of patients needing to lower their bad cholesterol.

NEXLETOLTM(bempedoic acid) Tablet

NEXLETOL is a first-in-class ATP Citrate Lyase (ACL) inhibitor that lowers LDL-C by reducing cholesterol biosynthesis and up-regulating LDL receptors. Phase 3 studies detailed in the label were conducted in more than 3,000 patients, with over 2,000 patients treated with NEXLETOL, demonstrated an average 18 percent placebo corrected LDL-C lowering when used in patients on moderate or high-intensity statins. NEXLETOL was approved by the FDA in February 2020.

Indication and Limitation of Use

NEXLETOL is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C. The effect of NEXLETOL on cardiovascular morbidity and mortality has not been determined.

Important Safety Information

Warnings and Precautions:

Adverse Reactions:

Drug Interactions:

Use in Specific Populations

Patients or their physicians are encouraged to report negative side effects of prescription drugs to the FDA. Visitwww.fda.gov/medwatchor call 1-800-FDA-1088 or report side effects to Esperion at 833-377-7633 (833 ESPRMED).

Click here to see thefull prescribing informationfor NEXLETOLTM(bempedoic acid) tablet.

NEXLIZETTM(bempedoic acid and ezetimibe) Tablet

NEXLIZET contains bempedoic acid and ezetimibe and lowers elevated LDL-C through complementary mechanisms of action by inhibiting cholesterol synthesis in the liver and absorption in the intestine. Phase 3 data demonstrated NEXLIZET lowered LDL-C by a mean of 38 percent compared to placebo when added on to maximally tolerated statins. NEXLIZET was approved by the FDA in February 2020.

Indication and Limitation of UseNEXLIZET is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C. The effect of NEXLIZET on cardiovascular morbidity and mortality has not been determined.

Important Safety Information

Contraindications:

Warnings and Precautions:

Adverse Reactions:

Drug Interactions:

Use in Specific Populations

Click here to see thefull prescribing information for NEXLIZET (bempedoic acid and ezetimibe) tablet. Patients or their physicians are encouraged to report negative side effects of prescription drugs to the FDA. Visitwww.fda.gov/medwatchor call 1-800-FDA-1088 or report side effects to Esperion at 833-377-7633 (833 ESPRMED).

CLEARCardiovascularOutcomes Trial

The effect of NEXLETOL on cardiovascular morbidity and mortality has not been determined. Esperion initiated a global cardiovascular outcomes trial (CVOT) to assess the effects of bempedoic acid on the occurrence of major cardiovascular events in patients with, or at high risk for, cardiovascular disease (CVD) who are only able to tolerate less than the lowest approved daily starting dose of a statin and are considered "statin averse." The CVOT known as CLEAR Cardiovascular Outcomes Trial is an event-driven, global, randomized, double-blind, placebo-controlled study that completed enrollment in August 2019 of 14,032 patients with hypercholesterolemia and high CVD risk at over 1,400 sites in 32 countries.

Esperion Therapeutics

Through scientific and clinical excellence, and a deep understanding of cholesterol biology, the experienced Lipid Management Team at Esperion is committed to developing new LDL-C lowering medicines that will make a substantial impact on reducing global cardiovascular disease, the leading cause of death around the world. For more information, please visitwww.esperion.comand follow us on Twitter atwww.twitter.com/EsperionInc.

Esperion Therapeutics Commitment to Patients with Hyperlipidemia

High levels of LDL-C can lead to a build-up of fat and cholesterol in and on artery walls (known as atherosclerosis), potentially leading to cardiovascular events, including heart attack and stroke. In the U.S., 96 million people, or more than 37 percent of the adult population, have elevated LDL-C. There are approximately 18 million people in the U.S. living with elevated levels of LDL-C despite taking maximally tolerated lipid-modifying therapy including individuals considered statin averse leaving them at high risk for cardiovascular events1. In the United States, more than 50 percent of atherosclerotic cardiovascular disease (ASCVD) patients and heterozygous familial hypercholesterolemia (HeFH) patients who are not able to reach their guideline recommended LDL-C levels with statins alone need less than a 40 percent reduction to reach their LDL-C threshold goal2.

Esperion's mission as the Lipid Management Company is to deliver oral, once-daily medicines that complement existing oral drugs to provide the additional LDL-C lowering that these patients need.

Forward-Looking Statements

This press release contains forward-looking statements that are made pursuant to the safe harbor provisions of the federal securities laws, including statements regarding the regulatory approval pathway for bempedoic acid tablet and the bempedoic acid / ezetimibe fixed dose combination tablet, the therapeutic potential of, and the clinical development plan for bempedoic acid tablet and the bempedoic acid / ezetimibe fixed dose combination tablet, including Esperion's timing, designs, plans for announcement of results regarding its CLEAR Outcomes study and other ongoing clinical studies for bempedoic acid tablet and the bempedoic acid / ezetimibe combination fixed dose tablet, timing for the review and approval of the NDAs and the MAAs, and Esperion's expectations for the market for medicines to lower LDL-C, including the commercial launch and market adoption of bempedoic acid tablet and the bempedoic acid / ezetimibe fixed dose combination tablet, if approved. Any express or implied statements contained in this press release that are not statements of historical fact may be deemed to be forward-looking statements. Forward-looking statements involve risks and uncertainties that could cause Esperion's actual results to differ significantly from those projected, including, without limitation, delays or failures in Esperions studies, that positive results from a clinical study of bempedoic acid may not be sufficient for EMA approval or necessarily be predictive of the results of future or ongoing clinical studies, that notwithstanding the completion of Esperions Phase 3 clinical development program for LDL-C lowering, the FDA or EMA require additional development in connection with seeking regulatory approval, or approval of an expanded indication, that existing cash resources may be used more quickly than anticipated, and the risks detailed in Esperion's filings with the Securities and Exchange Commission. Esperion disclaims any obligation or undertaking to update or revise any forward-looking statements contained in this press release, other than to the extent required by law.

References(1)Esperion market research on file: research project interviewing 350 physicians. Esperion Therapeutics, Inc. Sept-Oct 2018.(2)Data on file: analysis of NHANES database. Esperion Therapeutics, Inc. 2018.

Investor Contact:Alex SchwartzEsperion734-249-3386aschwartz@esperion.com

Media Contact:Ben ChurchEsperion734-864-6774bchurch@esperion.com

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Esperion Announces Three Data Presentations of the NEXLETOL (bempedoic acid) Tablet and the NEXLIZET (bempedoic acid and ezetimibe) Tablet at the...

The Global Chef: Diet and the fight against disease in West Africa – Traverse City Record Eagle

Posted: March 29, 2020 at 2:46 am

In the years 2014 through 2016 West Africa witnessed the largest Ebola virus outbreak since the virus was first discovered in 1976. The outbreak began in a rural Guinea village with a small boy and then his family. In weeks, Ebola travelled from the village across land borders to Sierra Leone and Liberia and spread to urban areas.

Within months Ebola became a global pandemic. In those two years, more than 11,000 people died in West Africa alone. (EVD kills 50 percent to 90 percent.) Ebola is still not fully eradicated.

West Africans have had to deal long and painfully with this virulent disease. To combat Ebola, or any disease, requires the dedicated work of doctors, nurses, scientists, government and life-saving medications together with our work of strengthening our immune systems.

That always includes diet. It may be the difference between surviving and dying.

Fumiaki Imamura and his research team from the University of Cambridge conducted a study analyzing West African diets for foods such as fruit, vegetables, legumes, whole grains, and fish, as well as foods containing fiber and omega-3s. The study used self-reported diet surveys from 187 countries, home to 89% of the worlds adult population. They also looked at the intake of unhealthy foods like sugary drinks, saturated fats and processed meats. (Researchers did not look at quantity of food 24 percent of West Africans are starving.)

According to the study, published in 2015 The Lancet Global Health, Taken all together, Sub-Saharan Africa, particularly West Africa, ranked better than wealthier regions in North America and Europe, probably because of a diet comprised of lean meats, vegetables, legumes and staple starches, with less processed foods than countries that fared worse (such as the U.S. and Russia). The study concluded that (most) inhabitants of West Africa enjoy healthier diets than counterparts in the United States, the United Kingdom, Japan or Canada.

Looking at just diet quality is not perfect, we know, Imamura said. For better public health, we should all look at social and environmental factors.

The studys shocking conclusion is that our eating habits are getting worse. Worldwide consumption of healthy foods has increased, but in wealthy countries that is outstripped by the growing consumption of unhealthy foods.

Fear of African food has led many people to avoid it. Africa is abundant with native foods, but very few are known, perhaps because of a perception that they are somehow inferior.

According to the National Academy of Sciences, Africa has more indigenous grains (millet, amaranth, groundnuts and rice) and native food plants (more than 2,000) than any other continent. Other indigenous foods include desert dates, butterfruit, kei apple, custard apples, guinea bananas, star apples, spirulina, tamarind, mushrooms, Ethiopian mustard, Hausa potatoes, tiger nuts, African bitter eggplant, spinach-like leaves of rosella plant, varieties of yams and legumes, and many herbs and spices.

In the online journal Nature, author Rachel Cernansky writes that Raymond Vodouhe, a plant breeder and geneticist with Bioversity International in Cotonou, Benin, and his team have focused work in West Africa on domesticating wild vegetables. Hardy wild plants help African families get through periods of drought or crop failure. Wild plants are threatened by deforestation and land-clearing. Researchers are domesticating wild vegetables so farmers have reliable access to indigenous vegetables and can better endure lean times.

Watermelon, coffee, black-eyed peas, kidney beans, sesame and okra migrated with slaves to the Caribbean, Europe and the New World. Along with abundant seafood (West Africa sits on the Atlantic Ocean), many legumes, whole grains, roots, tubers and greens this is a cuisine worth exploring.

Cookbook author and culinary historian Jessica B. Harris thinks that chicken yassa is an important key that opens the door for some people to African food. With simple ingredients, it is non-threatening. Its brilliant flavor comes from first being marinated, then grilled, and finally, stewed. Harris notes that all three techniques contribute to this strange and wondrous dish. Some recipes call for olives, carrots, and Dijon mustard to be simmered with the chicken.

Yields about 10 cups, 6 to 8 servings

6 lbs. bone-in chicken breasts, legs and thighs

1-1/4 to 1-1/3 C. fresh lime juice

5 T. olive or peanut oil, divided

2 chicken bouillon cubes, mashed (Maggi is good)

8 to 9 C. halved and sliced 1/4-inch thick onions

1 Scotch Bonnet chili

Cooked rice

Remove skin and excess fat from chicken parts and discard to yield 5-1/4 to 5-1/2 pounds chicken.

Zest 3 limes. Pour lime juice and zest into large mixing bowl. Stir in 2 tablespoons oil and bouillon cubes until dissolved. Transfer onions and chicken to bowl and rub mixture into chicken parts. Cover bowl and marinate 1 hour at room temperature or 2 hours refrigerated. Turn chicken halfway during marination. Remove chicken and drain excess marinade back into bowl.

Place chicken onto parchment-covered sheet pan or in mixing bowl and season with salt. Set a strainer over another bowl and pour marinade through. (Allow onions to drain while chicken cooks.) Reserve both onions and marinade separately.

Preheat broiler or grill over high heat. Working in batches, grill or broil chicken pieces, turning once, until browned but not cooked through. Set chicken aside in a bowl.

Heat remaining 3 tablespoons oil in a heavy 8-quart pot over medium heat. Add reserved drained onions, cover, and cook until soft and browned, 25 to 30 minutes. Sugars from the lime juice will caramelize on the bottom of the pan; stir onions and scrape bottom of pan occasionally. Pour marinade and the chili into onions. Transfer grilled chicken and any collected juices to pot, and tuck chicken into onions. Bring to a boil, lower heat, and simmer, partially covered, until chicken is cooked through, 30 to 45 minutes. Turn chicken once or twice so it cooks evenly.

To Serve: With tongs, transfer chicken to a platter. Taste sauce and season with salt if necessary. Pour or spoon onion sauce over top of chicken. Serve with rice.

Adapted from Yolele! Recipes from the Heart of Senegal by Pierre Thiam.

Black-eyed peas dont need long soaking and cooking so theyre ideal for meals in the heat of Africa or summer.

Yields 8 cups, 6 to 8 servings

2 C. dry black-eyed peas

1 to 1-1/3 C. peeled and 1/4-inch cubed tomato

1-1/4 C. peeled, seeded and 1/4-inch cubed cucumber

1 C. cored, seeded and 1/4-inch cubed red or green bell pepper

2/3 to 1 C. trimmed and finely sliced green onions

1 C. coarsely chopped Italian parsley

1 Scotch Bonnet or Serrano chili, stemmed, seeded and diced, to taste

1/2 C. olive or peanut oil

1/3 C. fresh lime juice, to taste

Rinse black-eyed peas, and soak in cold water 1 hour. Drain. Pour peas into 4-quart saucepan with 1 quart cold water. Bring to a boil over high heat. Lower heat to a simmer and cover. Simmer until peas are tender but not splitting, about 30 minutes. Strain peas, season with salt, and set aside.

In a large mixing bowl, toss together tomato, cucumber, bell pepper, green onions, parsley, and chili. Fold in oil, lime juice, salt, and freshly ground black pepper to taste. Fold in cooked black-eyed peas. Cover salad and allow flavors to develop 1 hour. Taste and season with more lime juice, salt, or pepper.

To Serve: Pile salad into serving vessel and serve chilled or at room temperature.

Adapted from Yolele! Recipes From the Heart of Senegal by Pierre Thiam.

This salad brings to mind a French Salade Nicoise, the classic composed salad. Senegalese cooks often stuff prawn or shrimp salads into avocado halves and serve as appetizers.

Adapted from Discovering Global Cuisines by Nancy Krcek Allen

Yields 4 servings

1 C. black-eyed peas

1/4 C. peeled and finely diced onion

3 T. oil, divided

6 T. fresh lime juice

2 large eggs

1 medium red bell pepper or 2 ounces sliced canned pimento

16 large peeled and de-veined shrimp

4 C./4 ounces clean, torn lettuce or baby greens

5 oz. plum tomatoes

Garnish: Italian parsley leaves

Soak black-eyed peas 1 hour in cold water. Drain peas, pour into 2-quart saucepan, and cover with water. Bring to a boil, lower heat, and simmer peas until tender, about 30 minutes. Cool peas and drain to yield about 2-1/2 cups cooked peas.

Measure 2 cups drained peas and set the extra 1/2 cup aside for another use. Toss 2 cups drained peas with onion, 2 tablespoons oil, and 2 tablespoons fresh lime juice. Season with salt and pepper; set dressed peas aside.

Place eggs into 2-quart saucepan and cover with cold water. Bring to a boil, cover pan and remove pan from heat. Time eggs 12 minutes. Remove eggs from hot water, crack the ends, and place in bowl of cold water 10 minutes. Peel eggs and quarter lengthwise into 8 wedges. Set aside.

Roast bell pepper over flame or under broiler until evenly blackened. Set aside in bowl, covered, until cooled. Peel pepper and discard stem, skin, membranes, and all seeds. Slice into thin julienne to yield about 1/2 cup, and set aside.

Steam shrimp or prawns until just cooked through and opaque, 3 to 5 minutes. Remove from steamer and cool. Refrigerate until needed.

Dice peeled avocado halves into 3/8- to 1/2-inch cubes and toss with 4 tablespoons lime juice and 1 tablespoon oil. Season with salt and pepper. Set aside.

Line up 4 large salad plates or shallow bowls. Lay a fourth of the lettuce on each plate. On each plate: Pile 1/2-cup black-eyed peas in the center. Spoon a fourth of avocado mixture over peas and greens. Slice plum tomato into twelve 1/4-inch thick rounds. Arrange 3 slices of tomato, 2 quarters hard-cooked egg and 4 prawns around the sides. Arrange sliced bell peppers (there will be some left over) or pimento slices across the top of the salad.

To Serve: Garnish salad with parsley leaves. Serve with salt and pepper grinder on table. Advise diners to toss salad before eating.

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The Global Chef: Diet and the fight against disease in West Africa - Traverse City Record Eagle

Suffering from thinning hair? Your diet could be the reason why – Telegraph.co.uk

Posted: March 29, 2020 at 2:46 am

Lets talk about hair loss. Yes, I know its not the sexiest beauty topic, but its nonetheless something many of us will have to deal with. It can be genetic, of course, which is classed as female pattern hair loss and is caused by an increase in male hormones in the body. Stress has an impact, too (it raises the testosterone levels in women), but what experts are increasingly seeing is diet-related hair loss.

Leading trichologist Anabel Kingsley has noted a rise in cases where women have lost hair after following a fad diet. Your hair is an essential tissue, she explains. If you dont have enough calories, carbohydrates or fats in your diet, your hair is the first thing to suffer. Your hair cells are the second-fastest dividing cells in your body and they need energy from carbohydrates to regenerate.

A lack of protein can also cause brittle hair, Kingsley tells me, but her biggest no-no? Juice fasting is awful for your hair. You can guarantee six to 12 weeks after a juice cleanse youll experience hair loss. Kingsley also suggests doing your homework before trying veganism, because it can have a detrimental effect on the hair. Always take a vitamin B12 supplement (its not found in plants), get plenty of iron from leafy greens and eat quinoa and chia seeds, which have complete proteins.

Everyone, vegan or not, should take a vitamin D capsule supplement to promote hair growth, too, says Kingsley. Every hair follicle has a vitamin D receptor, which influences the hair-growth cycle. Low vitamin D is linked to alopecia, so taking a supplement is an easy win to help with hair loss.

Thinning hair is trickier to style, too. In a recent survey of 2,000 women, Tresemm found that over half of us regularly have a bad hair day, whether its a lack of volume or hard-to-style cuts. I can relate. I met with the celebrity hairstylist Jenny Cho recently (she counts Scarlett Johansson and Charlize Theron among her regulars) and she shared her tips for managing thinning hair on a daily basis.

Dont brush your hair when its wet and tangled from the roots down, she advises. Start from the ends with a detangling brush and gently work your way up to the roots to prevent any breakage. Jenny also suggests using old-school mousse, such as Thickening Mousse by Bumble and bumble, to get more volume. (Before you say anything, mousse has come a long way from its crunchy 80s roots.) Use with abandon, ditch the juicediets and get some vitamin D.

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Suffering from thinning hair? Your diet could be the reason why - Telegraph.co.uk

Ayurvedic diet: Healthy conversion of lose weight with a Diet – The KXAN 36 News

Posted: March 29, 2020 at 2:46 am

For over 3500 years, people according to Ayurveda, an Indian science of health, which sees in the body the three fields of energy (Doshas): Vata, Pitta and Kapha life.

the theory:

is the Kapha Is too strong, it causes Obesity, as the body through improper diet to a lot of slag to form. Almost daily, massage and Yoga to bring the three in line and a reduction of the weight difference.

What are you allowed to eat?

salad, vegetables, milk, Oil and preferably Ghee (clarified Butter). Everything is diverse and seasoned, is to drink hot water. Meat, fish and eggs in moderation. Alcohol should be avoided.

using The decreasing promise: about a Kilo per month.

get the free vocabulary The food and preparation of Ayurvedic Kches to bring the Doshas in Balance and keep in line.

get the free vocabulary The Ayurvedic diet means that, for Most, a change in Diet.

The main meal is lunch, eaten in the evening should be light and not after 19 oclock to eat. Important: rest and attention when you eat.

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Ayurvedic diet: Healthy conversion of lose weight with a Diet - The KXAN 36 News

Exercise and diet with the that Adele got her new figure – Play Crazy Game

Posted: March 29, 2020 at 2:46 am

The british singer stars in a amazing weight loss

Last week, Adele debuted a new look on the birthday party of Drake.

Always elegant, but above all much more thin. Already this year, we had noticed the singer more interested in the gym, and less voluptuous. Month-to-month, and despite being very private even to post pics, we saw how the british lost weight. First, the media pointed out that this was due to his divorce, but what is certain is that Adele did it for herself and for her son, according to People.com.

Today, with about 10 kilograms less than several months ago, the singer of Someone like you looks fantastic, and it is all thanks to a particular diet, and 3 types of exercises, training several times a day, have given a new figure that is displaying with pride.

Watch in the video above all the details of the scheme almost obsessive Adele.

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Raju has an exquisite taste. For him, video games are more than entertainment and he likes to discuss forms and art.

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Exercise and diet with the that Adele got her new figure - Play Crazy Game


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