Editor's Choice Main Category: Nutrition / Diet Also Included In: Obesity / Weight Loss / Fitness Article Date: 26 Jun 2012 - 0:00 PDT
Current ratings for: 'Vitamin B3 Found In Milk May Result In Substantial Health Benefits'
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According to the June issue of Cell Metabolism, high doses of the niacin-related vitamin precursor nicotinamide riboside (NR) prevent obesity in mice that have been fed a fatty diet. Furthermore, it increases muscle performance and energy expenditure, whilst preventing the development of diabetes development without any side effects.
The mouse experiment was designed by research leader Dr. Johan Auwerx and his Swiss team, whilst the team from Weill Cornell Medical College, who played leading role in uncovering the biological story of NR, found a method to administer sufficient doses of NR to the animals.
Dr. Anthony Sauve, a pharmacologist and organic chemist and associate professor of Pharmacology at Weill Cornell Medical College, remarked: "This study is very important. It shows that in animals, the use of NR offers the health benefits of a low-calorie diet and exercise - without doing either one."
Dr. Sauve, a pioneer and leader in investigating how NAD can signal adaptation in cells and in physiology, invented a simple method to efficiently synthesize NR on a large scale, was the first scientist to demonstrate that NR elevates nicotinamide adenine dinucleotide (NAD) levels in mammalian cells. NAD plays a key role in energy metabolism.
He states:
According to the Swiss team, NR is a "hidden vitamin", which is thought to occur in low levels in numerous foods, even though it is difficult to measure these levels. Overall, the researchers call the metabolic effects of NR "nothing short of astonishing."
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Vitamin B3 Found In Milk May Result In Substantial Health Benefits
