AUSTIN, Texas -- Abby Solomons purse looks like a traveling pantry, full of sugary snacks.
My life basically revolves around food, she said.
And yet for all she eats, shes in a constant battle with starvation.
CBS News
Abby was born with a rare genetic disorder called neonatal progeroid syndrome. The mutation mangles noses and makes Abby look prematurely old.
It also prevents her body from making enough asprosin, a hormone that stimulates appetite.
Shes not hungry but still needs to eat all the time. The food feeds her brain just enough glucose to keep her from passing out.
But after a few bites, she feels full. Abby consumes half the amount of normal calories for a woman her age; and at 5 feet 10 inches, weighs just 99 pounds.
Shes eating, but not gaining weight.
I mean, its weird. I agree, Abby said.
Dr. Atul Chopra doesnt think its weird.
I think we are very fortunate that our paths crossed, mine and Abbys, Chopra said.
He thinks it could be an exciting breakthrough in the fight against obesity and diabetes.
CBS News
A geneticist at Baylor College of Medicine in Houston, Chopra analyzed Abbys DNA and replicated her condition in lab mice.
Hes now developing an antibody designed to shut down aprosins effect on the body.
That would be the hope here, that we can inject diabetic obese humans with an antibody against asprosin. And if it works anything like how it works in mice, then I think we have a game changer, Chopra said.
It certainly would be for Thomeshia Jones.
I dont like looking at myself in the mirror, she said.
At 17 years old, she weighs 380 pounds.
I was getting picked on every day. Like, non-stop, every day, she said.
CBS News
While Thomeshia is learning better eating habits at Texas Childrens Hospital teenage obesity program, she is desperate.
Next month, she will have bariatric surgery, which is something she would definitely avoid if she could.
Just the thought of surgery is scary. So if theres a way I can go about it without surgery, Im willing to do that, she said.
Which is just what Abby Solomons DNA may soon offer in the battle against obesity and diabetes.
Thats so cool, Abby said. I guess thats what I was put here to do. And thats why I was born this way.
Finally, Abbys appetite is voracious; Hungry to help.
2017 CBS Interactive Inc. All Rights Reserved.
See the rest here:
Woman's rare genetic disorder could hold the key to weight loss - CBS News
